Managing the Drug Discovery Process, Second Edition thoroughly examines the current state of pharmaceutical research and development by providing experienced perspectives on biomedical research, drug hunting and innovation, including the requisite educational paths that enable students to chart a career path in this field. The book also considers the interplay of stakeholders, consumers, and drug firms with respect to a myriad of factors. Since drug research can be a high-risk, high-payoff industry, it is important to students and researchers to understand how to effectively and strategically manage both their careers and the drug discovery process. This new edition takes a closer look at the challenges and opportunities for new medicines and examines not only the current research milieu that will deliver novel therapies, but also how the latest discoveries can be deployed to ensure a robust healthcare and pharmacoeconomic future. All chapters have been revised and expanded with new discussions on remarkable advances including CRISPR and the latest gene therapies, RNA-based technologies being deployed as vaccines as well as therapeutics, checkpoint inhibitors and CAR-T approaches that cure cancer, diagnostics and medical devices, entrepreneurship, and AI. Written in an engaging manner and including memorable insights, this book is aimed at anyone interested in helping to save countless more lives through science. A valuable and compelling resource, this is a must-read for all students, educators, practitioners, and researchers at large—indeed, anyone who touches this critical sphere of global impact—in and around academia and the biotechnology/pharmaceutical industry. - Considers drug discovery in multiple R&D venues - big pharma, large biotech, start-up ventures, academia, and nonprofit research institutes - with a clear description of the degrees and training that will prepare students well for a career in this arena - Analyzes the organization of pharmaceutical R&D, taking into account human resources considerations like recruitment and configuration, management of discovery and development processes, and the coordination of internal research within, and beyond, the organization, including outsourced work - Presents a consistent, well-connected, and logical dialogue that readers will find both comprehensive and approachable - Addresses new areas such as CRISPR gene editing technologies and RNA-based drugs and vaccines, personalized medicine and ethical and moral issues, AI/machine learning and other in silico approaches, as well as completely updating all chapters
Darkstar Rising By Susan K. Hamilton Live by the sword. Die by the sword. Youngest daughter of the ruling house of Illauren, Princess Kiara - the Darkstar - has worked tirelessly to undermine the rule of the Pretender-Queen, Ushan, and restore her brother to his rightful place on the throne. Now the time has come, and Darkstar is riding out to bring the people of Illauren to her brothers side. But an accident changes her plans. Darkstar suddenly discovers secrets about herself that have been hidden since childhood. Secrets that will transform her from an "ordinary" princess into one of the most powerful women on the continent. And with that power comes choices. Choices that may change the course of history itself. Choices that could destroy everyone and everything Darkstar is fighting to protect
Provides reproducible outline portraits of 15 scientists who lived between 384 B.C. and 1955 A.D., and brief biographical information about each individual.
Provides reproducible outline portraits of 15 mathematicians who lived between 624 B.C. and 1624 A.D., and brief biographical information about each individual.
Provides short biographies and reproducible outline portraits of 15 scientists: Maria Mitchell, Marie Curie, Mary Engle Pennington, Lillie Minoka-Hill, Lise Meitner, Margaret Morse Nice, Tilly Edinger, Maria Goeppert-Mayer, Rachel Carson, Myra Adele Logan, Dorothy Crowfoot Hodgkin, Chien-Shiung Wu, Rosalind Franklin, Eugenie Clark, and Angella Ferguson.
Outstanding contributors to mathematics are profiled in reproducible one-page biographies and line-drawn portraits. The first book in this three-part series, Mathematicians, Book I, highlights the mathematicians from 624 B.C. to 1642 A.D., such as Pythagoras, Plato, Aristotle, Fibonacci, Galileo, and Euclid, and their mathematical findings. In Mathematicians, Book II, mathematicians from 1571 to 1855, such as Descartes, Pascal, Gregory, Newton, Bernoulli, Leibnez, and Euler, teach students about the fascinating mathematical revelations from the 16th to 19th centuries. Woman Mathematicians highlights the lives and work of female mathematicians from Hypatia, Agnesi, Germain, and Somerville to Lovelace, Kovalevskaya, Scott, Young, and many more!
Provides reproducible outline portraits of 15 scientists who lived between 384 B.C. and 1955 A.D., and brief biographical information about each individual.
This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work. This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.
This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work. This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.
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