Surya K. De's Books

Medicines for Cancer

Mechanism of Action and Clinical Pharmacology of Chemo, Hormonal, Targeted, and Immunotherapies

By: Surya K. De

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Medicines for Cancer

Mechanism of Action and Clinical Pharmacology of Chemo, Hormonal, Targeted, and Immunotherapies

By: Surya K. De

Medicines for Cancer: Mechanism of Action and Clinical Pharmacology of Chemo, Hormonal, Targeted, and Immunotherapies covers most known anti-cancer therapeutics. Cancer is the second leading cause of death worldwide, with its various forms resulting in nearly one out of every six mortalities each year. This book describes all US FDA-approved drugs (up to 2021), such as small molecules, peptides, monoclonal antibodies, whole antibodies, gene therapy, antibody-drug conjugates, cell therapy, and immunotherapies, along with information on their generic and brand names, medical uses, details dosage, mechanisms of actions, pharmacokinetics and side effects. Chemical structures of small molecules, small peptides, antibody-drug conjugates are also provided. This book is ideal for medicinal chemists, oncologists, and pharmacologists, but it will also be indispensable for professional researchers, whether they are working in the clinic or the pharmaceutical industry. - Covers precise information on each drug treatment - Catalogues and lists all FDA-approved drugs for cancer group by chemical classes - Provides easy access to specific drugs

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Page Count

634

Publisher

Elsevier

Published Date

ISBN 10

0443133131

ISBN 13

9780443133138

Applied Organic Chemistry

Reaction Mechanisms and Experimental Procedures in Medicinal Chemistry

By: Surya K. De

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Applied Organic Chemistry

Reaction Mechanisms and Experimental Procedures in Medicinal Chemistry

By: Surya K. De

An indispensable guide for all synthetic chemists who want to learn about the most relevant reactions and reagents employed to synthesize important heterocycles and drugs! The synthesis of natural products, bioactive compounds, pharmaceuticals, and drugs is of fundamental interest in modern organic chemistry. New reagents and reaction methods towards these molecules are being constantly developed. By understanding the mechanisms involved and scope and limitations of each reaction applied, organic chemists can further improve existing reaction protocols and develop novel efficient synthetic routes towards frequently used drugs, such as Aspirin or Penicillin. Applied Organic Chemistry provides a summary of important (name) reactions and reagents applied in modern organic chemistry and drug synthesis. It covers rearrangement, condensation, olefination, metathesis, aromatic electrophilic substitutions, Pd-catalyzed C-C bond forming reactions, multi-component reactions, as well as oxidations and reductions. Each chapter is clearly structured, providing valuable information on reaction details, step-by-step mechanism, experimental procedures, applications, and (patent) references. By providing mechanistic information and representative experimental procedures, this book is an indispensable guide for researchers and professionals in organic chemistry, natural product synthesis, pharmaceutical, and medicinal chemistry, as well as post-graduates preparing themselves for a job in the pharmaceutical industry. Hot Topic: Reviews important classes of organic reactions (incl. name reactions) and reagents in medicinal chemistry. Useful: Provides information on reaction details, common reagents, and functional group transformations used to synthesize natural products, bioactive compounds, drugs, and pharmaceuticals, e.g. Aspirin, Penicillin. Unique: For every reaction the mechanism is explained step by step, and representative experimental procedures are given, unlike most books in this area. User-friendly: Chapters are clearly structured making it easy for the reader to compare different reactions. Applied Organic Chemistry is an indispensable guide for researchers and professionals in organic chemistry, natural product synthesis, pharmaceutical, and medicinal chemistry, as well as post-graduates preparing themselves for a job in the pharmaceutical industry.

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Page Count

856

Publisher

John Wiley & Sons

Published Date

ISBN 10

3527347852

ISBN 13

9783527347858

Fundamentals of Cancer Detection, Treatment, and Prevention

By: Surya K. De

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Fundamentals of Cancer Detection, Treatment, and Prevention

By: Surya K. De

Fundamentals of Cancer Detection, Treatment, and Prevention The professional guide to cancer diagnosis and therapy for researchers and clinicians In Fundamentals of Cancer Detection, Treatment, and Prevention, distinguished researcher Surya K. De delivers a concise and authoritative guide to cancer treatment, diagnosis, and prevention. The book offers a comprehensive overview of cancer in humans, from its causes, symptoms, and diagnosis to the variety of treatment options available today. Intuitively organized by cancer type, this guide provides concise information on risk factors, diagnosis, and treatment options for all commonly encountered tumors, including surgery, radiation therapy, chemotherapy, and immunotherapy. All US FDA-approved drugs—like small molecules, peptides, monoclonal antibodies, whole antibodies, gene therapy, antibody-drug conjugates, and cell therapies—are considered, and information about their generic and brand names, clinical uses, and mechanisms of action is presented. Readers will also find: A thorough overview of human cancers, including cancer risk factors and possible preventions Comprehensive explorations of bladder, blood, brain, and spinal cord cancers Practical discussions of breast, colorectal, cervical, kidney, and liver cancer In-depth examinations of lung, skin, ovarian, vaginal, vulvar, pancreatic, and prostate cancers, as well as mesothelioma Perfect for pharmaceutical chemists, oncologists, pharmacologists, and medicinal chemists, Fundamentals of Cancer Detection, Treatment, and Prevention is an indispensable guide for professional researchers, whether they are working in the clinic or the pharmaceutical industry.

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Page Count

500

Publisher

John Wiley & Sons

Published Date

ISBN 10

3527838570

ISBN 13

9783527838578

Hydrocarbon Chemistry

By: George A. Olah,Arpad Molnar,G. K. Surya Prakash

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Hydrocarbon Chemistry

By: George A. Olah,Arpad Molnar,G. K. Surya Prakash

This book provides an unparalleled contemporary assessment of hydrocarbon chemistry – presenting basic concepts, current research, and future applications. • Comprehensive and updated review and discussion of the field of hydrocarbon chemistry • Includes literature coverage since the publication of the previous edition • Expands or adds coverage of: carboxylation, sustainable hydrocarbons, extraterrestrial hydrocarbons • Addresses a topic of special relevance in contemporary science, since hydrocarbons play a role as a possible replacement for coal, petroleum oil, and natural gas as well as their environmentally safe use • Reviews of prior edition: “...literature coverage is comprehensive and ideal for quickly reviewing specific topics...of most value to industrial chemists...” (Angewandte Chemie) and “...useful for chemical engineers as well as engineers in the chemical and petrochemical industries.” (Petroleum Science and Technology)

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Page Count

1240

Publisher

John Wiley & Sons

Published Date

ISBN 10

1119390532

ISBN 13

9781119390534

Microstructure Sensitive Design for Performance Optimization

By: Brent L. Adams,Surya R. Kalidindi,David T. Fullwood

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Microstructure Sensitive Design for Performance Optimization

By: Brent L. Adams,Surya R. Kalidindi,David T. Fullwood

The accelerating rate at which new materials are appearing, and transforming the engineering world, only serves to emphasize the vast potential for novel material structure and related performance. Microstructure Sensitive Design for Performance Optimization (MSDPO) embodies a new methodology for systematic design of material microstructure to meet the requirements of design in optimal ways. Intended for materials engineers and researchers in industry, government and academia as well as upper level undergraduate and graduate students studying material science and engineering, MSDPO provides a novel mathematical framework that facilitates a rigorous consideration of the material microstructure as a continuous design variable in the field of engineering design. - Presents new methods and techniques for analysis and optimum design of materials at the microstructure level - Authors' methodology introduces spectral approaches not available in previous texts, such as the incorporation of crystallographic orientation as a variable in the design of engineered components with targeted elastic properties - Numerous illustrations and examples throughout the text help readers grasp the concepts

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