It Is A Collection Of Twelve Short Stories In The Characteristic Style Of The Author Creatively Employs Mythological Symbols To Manifest Collective Consciousness. Concealed In This Story Are Many Lessons For The Most Modern Fiction Writers Today. The Art Of Surendra Prakash Can Be Seen Scaling Dizzy Heights In This Work.
Written Indian history begins in sixth century bc with the history of Magadh (present day states of Jharkhand and Bihar). For almost a millennium Magadh dominated Indian history. The situation changed when Islamicized Turks entered India. The Mughals who followed the Turks ensured Bihar's economic prosperity; Patna became the most important centre of Himalayan trade. European Companies visited Patna to obtain a variety of goods, local as well as Himalayan. In the mid-eighteenth century Bihar and Bengal fell into the hands of Englishmen. A new chapter began. At the turn of the nineteenth century, Industrial Revolution began in Britain. The East India Company stopped trading in textiles. Instead, they promoted cotton cultivation in order that cotton was available to British textile factories. They promoted cultivation of indigo, needed by the textile manufacturing factories coming up. Land revenue source of the government's prime income, was collected even when agricultural output suffered massively. The government took deep interest in opium production but paid the cultivators less than the market price. British interference in agricultural matters caused wide spread agrarian distress. Indian society encountered many socio-religious reform movements. Raja Rammohun Roy and Swami Dayanand were major proponents of the new order. Stress was laid on gender equality, women empowerment and the modern system of education. Institutions for training doctors, engineers and scientists were opened. As time progressed, by and large, Biharis accepted the changes. Eventually social reform movements turned into the freedom movement in which Biharis played a leading role. This comprehensive volume is indispensable for scholars working on Bihar and modern and medieval South Asia. Please note: Taylor & Francis does not sell or distribute the Hardback in India, Pakistan, Nepal, Bhutan, Bangladesh and Sri Lanka
Gene therapy is emerging as a new class of therapeutics for the treatment of inherited and acquired diseases. However, poor cellular uptake and instability of DNA in the physiological milieu limits its therapeutic potential, hence a vector which can protect and efficiently transport DNA to the target cells must be developed. Nanotechnology-based non-viral vectors have been proposed as potential candidates. Various polymeric nanoparticles have been shown to be suitable, with high cellular uptake efficiencies and reduced cytotoxicity. These delivery vectors form condensed complexes with DNA which result in shielding against enzymatic degradation and enhanced cellular targeting. Advantages including easy manipulatibility, high stability, low cost and high payload, mean that nanoparticles from various polymers have been exploited. Gene therapy gives a systematic account of the many aspects of nanotechnology mediated gene therapy, from the preparation of nanoparticles to physicochemical characterization, and follows with applications in in vitro and in vivo models. This book emphasizes the various aspects of nanotechnology-based gene therapy, with initial chapters detailing the tools and techniques available for preparation and in vitro and in vivo characterization of nanoparticles. Later chapters provide exhaustive details on polymeric systems employed for gene therapy. Provides an overview of nanotechnology applications in gene therapy, from preparation of nanoparticles to in vitro and in vivo studies Details the tools and techniques available for preparation, characterization and in vitro and in vivo study of nanoparticles Details the limitations of nanoparticle-mediated gene therapy and proposes ways in which they may be overcome
The API (Association of Physicians of India) Textbook of Medicine consists of 28 sections across two comprehensive volumes covering a wide range of medical disorders. Fully revised and with 1588 images, illustrations and tables, this new edition has many new chapters on topics including nanotechnology and nano-medicine, and clinical approach to key manifestations. Each section is dedicated to a different medical phenomenon, including clinical pharmacology, endocrinology, dermatology, infectious diseases and nutrition. Also included is online access to teaching modules for teachers and students, questions and answers, an atlas/image bank, echocardiography and video EEG and common medical procedures with voice over.
Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids addresses several issues related to safe and effective delivery of nucleic acids (NAs) using nanoparticles. A further emphasis would be laid on the mechanism of delivery of NAs, the barriers encountered and the strategies adapted to combat them. An exhaustive account of the advantages as well shortcomings of all the delivery vectors being employed in delivery of various NAs will be provided. On final note the regulatory aspects of nanoparticles mediated NA would be discussed, with focus on their clinical relevance. The design and development of nucleic acid-based therapeutics for the treatment of diseases arising from genetic abnormalities has made significant progress over the past few years. NAs have been widely explored for the treatment of cancer and infectious diseases or to block cell proliferation and thereby caused diseases. Advances in synthetic oligonucleotide chemistry resulted in synthesis of NAs that are relatively stable in in vivo environments. However, cellular targeting and intracellular delivery of NAs still remains a challenge. Further development of NA-based therapeutics depends on the progress of safe and effective carriers for systemic administration. Nanomedicine has facilitated availability of vectors with diminished cytotoxicity and enhanced efficacy which are rapidly emerging as systems of choice. These vectors protect NAs from enzymatic degradation by forming condensed complexes along with targeted tissue and cellular delivery. During the past few years, a myriad reports have appeared reporting delivery of NAs mediated by nanoparticles. This book will provide an overview of nanoparticles being employed in the in vitro and in vivo delivery of therapeutically relevant NAs like DNA, siRNA, LNA, PNA, etc. - Provides a complete overview of the applicatiosn of nanomedicine in the delivery of nucleic acids, from characterization of nanoparticles, to in vitro and in vivo studies - Discusses delivery issues of less well explored nucleic acids, like PNAs, Ribozymes, DNAzymes, etc. - Summarizes the current state of research in nucleic acid delivery and underscores the future of nanomedicine in this field
Each year, Advances in Pediatrics focuses on providing current clinical information on important topics in pediatrics. This year, Dr. Carol Berkowitz has taken over as Editor, and she and her new editorial board have assembled top authors to provide updates on the following topics: Evaluation and Management of Febrile Infants
This pioneering work traces the migration of Indian traders to Russia, Iran, West Asia and South-East Asia in medieval times. The author concludes that Indian traders did not enjoy political and royal support, essential for success. He also affirms that crossing the seas did not lead to social boycott by their caste-men. This taboo came much later, probably with the advent of British rule in the nineteenth century. Please note: Taylor & Francis does not sell or distribute the Hardback in India, Pakistan, Nepal, Bhutan, Bangladesh and Sri Lanka
The Jain community in India, though small in number, is very important in the economic and social life of the country. Jain history becomes more important when we find that the community anticipated new commercial practices adopted by European trading countries from the sixteenth century onwards. Two Jain names stand out in history; they are Veerji Vora, in the seventeenth century and Jagat Seth of Bengal in the eighteenth century. A succession of Jagat Seths interacted with high government officials and were very influential in their time as this volume brings out.This volume contributes significantly to the study of merchant communities and colonial history in South Asia. Please note: Taylor & Francis does not sell or distribute the Hardback in India, Pakistan, Nepal, Bhutan, Bangladesh and Sri Lanka
The rapid technological development of new products, coupled with the growing consumer desire for the latest technology, has led to a new environmental problem: products that are discarded prematurely. But behind every problem lies an opportunity. Many of these products can be reprocessed, leading to savings in natural resources, energy, landfill s
This book discusses the experiences of cooperative enterprises in India that have been operated by or influenced to a significant extent by trade unions. It describes the origins of these movements in India presenting a political-strategic view of their development and, in some cases, their decline. The book also presents case studies of groundbreaking social experiments conducted in India in which trade unions have formed cooperatives for production and service provision for the working class movement. It also offers lessons learned from previous social experiments and explains how to use them for future strategies in the working class movement by using primary research undertaken on trade union cooperatives in India. With globalization often given as a reason for the decline of trade unions and transformative social movements, this book demonstrates that where movements declined it was due to their own internal weaknesses, while presenting successful case studies of movements which have shown resilience in the face of globalization. The book also gives an extensive criticism of India’s Self Employed Women’s Association as a model of a depoliticized trade union cooperative. The main lesson of this book is that cooperatives represent a viable strategy to build working class power in the 21st century in India, and elsewhere.
The book presents a comprehensive view of the Indian equity markets over the past two decades (1994-2014). Equity markets constitute the most important segment of stock exchanges; in fact, the status of equity returns is, by and large, considered as a barometer of the state of a country’s economy. Returns earned by the equity investors on their funds invested in equity markets have become a decisive factor in the growth of such markets. In this context, the book discusses all the major aspects of equity returns and also conducts a dis-aggregative analysis based on underlying factors like age, size, ownership structure, industry affiliation/sector, among others, to explain the factors affecting returns and risk. While on the one hand the study ascertains the market rates of return (earned) on equities from the investors’ perspective (by including both the capital gains and the dividend income), it also shows how to compute the rates of returns on equities from the corporate perspective (that is, rate of return earned on equity funds). It further assesses the required/expected rate of return and examines the volatility in stock returns, with a focus on its behaviour during the period of the study. It deepens investors’ understanding of equity investment, helping them to make more-informed investments. While of interest to the investor community, this book also contributes significantly to the existing literature on market returns and is a valuable reference resource for academics, researchers and market participants, financial institutions and other intermediaries, regulators and policy makers.
This work is the first monograph devoted solely to Bombax ceiba, popularly known as the Red Silk Cotton Tree. Consisting of seven chapters, it covers all relevant aspects of this plant, from its historical and spiritual importance, to its botanical characterization, pharmacognostical details and ethnobiological uses, to its scientific validation in various animal and human studies. Each part of the tree is of medicinal value and possesses many novel chemical constituents such as shamimicin, bombasin, bombamalone, bombamaloside etc. along with other bioactive secondary metabolites. The book presents the chemical structures of the most important constituents and highlights various pharmacological activities, predominantly antioxidant, anti-inflammatory, anti-mutagenic, hypoglycemic, hypotensive, hepatoprotective and fibrinolytic, which may prove to be a source for the development of a novel phyto-pharmaceutical agent to treat diabetes, heart disease and cancer. In addition, separate chapters deal with the commercial and ecological significance of B. ceiba, as well as a case study on its conservation. Numerous color illustrations are included to identify the plant and to justify its nickname, the “Little Bird’s Cafeteria”.
While there have been a large number of ongoing research projects and publications on the treatment of cancer, there is a limited number of books related to nanotechnology with emphasis on polymeric nanoparticles in cancer therapy. The book, covering all of the recent research work done on this basis, enlightens researchers and students with the benefits of polymeric nanomaterials in cancer. This book provides exhaustive knowledge on polymeric nanoparticles and cancer. - Provides a complete overview of the application of different polymeric nanoparticles in cancer therapeutics: from characterization of nanoparticles to in vitro and in vivo studies. - Contains a detailed description of the delivery of therapeutic molecules with different polymers realized with nanomedicine in cancer therapeutics. - Discusses newly developed promising polymers in cancer. - Describes polymeric nanoparticle and their role in theranostics pertaining to cancer. - Reviews clinical relevance of different polymeric formulations in the field of cancer
This book focuses on various aspects of nanotechnology based gene silencing. The initial chapters detail the techniques available for in vitro and in vivo characterization of nanoparticles. In the later chapters, exhaustive details about various polymeric systems employed for gene silencing has been accounted.
Grass pea (Lathyrus sativus L.) is an important cool-season legume species with wide genetic diversity spread across the continents. With the climate change scenario it has emerged as a viable crop option for fragile agro-ecosystems, where successful cultivation of major crop species is apparently not difficult. However, grass pea seeds are known to have a neurotoxin known as β-N-oxalyl-l-α, β-diaminopropionic acid (β-ODAP). Its overconsumption as a staple food in an unbalanced diet for an extended period of 3–4 months can cause spastic paraparesis of the legs in human beings. Therefore, β-ODAP needs to be reduced through genetic means to a safe level for human consumption. Unfortunately, a paucity of efforts towards development of genetic and genomic resources for this species has hampered the progress in breeding low ODAP varieties in the past. Some progress has been made in recent years for collection, conservation, characterization, evaluation and utilization of Lathyrus genetic resources at the national and international levels, resulting in large ex situ collections in various gene banks of the world. These resources need to be systematically characterized and evaluated for genetic improvement through conventional and contemporary approaches. In spite of a large number of wild relatives with useful traits, no significant efforts have been made for alien gene transfer in grass pea. This chapter reviews the present status of genetic and genomic resources of Lathyrus and their use in current breeding programmes.
This book systematically analyzes why constitutions do not survive in Nepal, despite sixty years of constitutional history. The author discusses the epistemology of ethnic federalism in Nepal and examines the challenges of nation building and post-nation constitutionalism. The work addresses the connection between ethnic identity, right to self-determination, constitution making and state restructuring, offering possible ways forward for Nepal. Chapters consider lessons to be drawn from the past and examine reasons for the abolition of monarchy in Nepal. The book highlights the major problems that the first elected Constituent Assembly (CA) faced in promulgating a new constitution, before it was dissolved in 2012. The concept of right to self-determination and its complexities at the domestic level are all explored, along with ways forward to address the problem of constitutionalism, ethnic federalism and democracy. The author offers solutions as to how the second CA could address problems to promulgate a new constitution. The book elaborates on the role that constitutionalism plays in constitution making and the survival of a constitution. Scholars of politics and international studies, policy makers and those with an interest in law and constitution in Asia will all find this work of interest.
This research paper examines Empowering Voices: The Role of Artificial Intelligence in Amplifying Women's Activism on Social Media in India the influence of social media on women‟s activism in India, highlighting its role in amplifying voices, fostering community, and mobilizing support for gender-related issues. Utilizing qualitative methods, including interviews with women activists and social media content analysis, the study identifies key themes in contemporary digital activism. The findings reveal that social media has empowered women to challenge societal norms and advocate for rights, notably through movements like #MeToo and the Shaheen Bagh protests. However, the paper also addresses significant challenges, such as online harassment and the need for intersectional representation. Overall, this research underscores the transformative potential of social media in shaping women‟s activism while advocating for safer digital spaces for all activists. The rise of social media has significantly transformed the landscape of activism across the globe. In India, women activists have leveraged these platforms to amplify their voices, mobilize support, and challenge societal norms. This paper explores the influence of social media on women‟s activism in India, focusing on its role in raising awareness, fostering community, and facilitating grassroots movements. Through qualitative analysis, this research highlights key case studies, explores various social media platforms, and examines the challenges faced by women activists in the digital space.
Courage to Dream' is not just a proud saga of passing the Civil Services Examination, it is a salute to the perseverance that makes man the best creature in the universe. 'Courage to Dream' is that perseverance which gives man the inspiration and courage to take up an insurmountable challenge. 'Courage to Dream' is a reality that has been experienced even before it became a piece of literature; and if someone finds a literary value in penning down such reality, then I shall consider myself blessed. In this book, there is love as well as yearning; there is struggle as well as success; there is shrewdness as well as innocence; there are roses as well as thorns. I could not save myself from getting brushed by the rarest colours of the life. The purpose of writing this book is not to glorify any person. Its purpose is to motivate the youth towards their path of duty with full dedication. If, after reading this book, even a single youth gets inspired to walk towards their dreams amid unfavourable circumstances, then I shall believe that I have succeeded in my purpose.
Step into the thrilling world of the "Chronicles of a Lady Police Inspector," where captivating short stories bring to life the gripping cases from the diaries of a tenacious detective. Brace yourself for a riveting journey through the intricate webs of crime, filled with unexpected twists and turns that will leave you on the edge of your seat. Each case is meticulously crafted to immerse you in the pulse-pounding world of police detection procedures. Experience firsthand the trials and tribulations faced by dedicated law enforcement personnel as they navigate the treacherous path of justice. Behind the headlines lie the untold stories of the traumatic experiences they endure, unveiling the relentless pursuit of truth amidst shrewd tactics employed by cunning culprits. Based on real-life police cases, these tales artfully blend fact and fiction, transporting you into the heart of the true cat-and-mouse game between hunter and hunted. With every page, you'll find yourself engrossed in the electrifying chase, unravelling clues alongside the Lady Police Inspector as she delves into the depths of the criminal underworld. Prepare to be captivated by these spellbinding stories that resonate with the essence of the 'who-done-it' genre. The "Chronicles of a Lady Police Inspector" will keep you guessing until the final revelation, as you embark on a captivating journey that will leave you breathless and craving for more. Get ready to unravel the secrets, solve the puzzles, and experience the thrill of justice served.
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