MOLECULAR BIOTECHNOLOGY Therapeutic Applications and Strategies SUNIL MAULIK and SALIL D. PATEL Recombinant DNA technology, or genetic engineering, has revolutionized our understanding of life at the molecular level-giving us a detailed picture of the living cell's functions and spawning diverse biotechnologies that use molecules, cells, tissues, and even entire organisms. This introduction to molecular biotechnology is a practical, up-to-date guide to this rapidly growing field. Based on courses taught by the authors to biotechnology professionals, Molecular Biotechnology: Therapeutic Applications and Strategies applies the principles of modern biotechnology to advances and trends in the development of therapeutic strategies and approaches to disease prevention and intervention. By focusing on select applications and strategies, this volume exemplifies the convergence of biological, chemical, and informational advances in the discovery of novel targets and drugs. This multidisciplinary approach, essential to the development of commercial therapeutic molecules, includes carefully selected real-world examples from the pharmaceutical and biotechnology industries. Specific topics covered include: * Genome Based Medicine and the Human Genome Project * Human Gene Therapy * Combinatorial Chemistry * Rational Drug Design * Reengineering the Immune System User-friendly and organized for maximum understanding, Molecular Biotechnology: Therapeutic Applications and Strategies is an excellent text/reference for biotechnology professionals, researchers, physicians, students, managers, industry analysts, and investors interested in learning more about the field of molecular biotechnology.
Kathak, the Indian classical dance form prevalent in the North, has a long past. Nurtured in the holy precincts of the Hindu temples, Kathak dance has over the centuries, attained refinement and enriched itself with various hues and embellishments. The art of story-telling which found expression in various forms like the Akhyana by the Manabhattas of Gujarat, the Pandavani by the artistes telling stories in Madhya Pradesh, the Harikathas and Kalakshepams of the South, the Kirtanas of the West, the art of Wari-liba, story-telling of the North-East, specially of Manipur, reflects the rich heritage Kathak has inherited over the years. In forms such as Baithakachi Lavani and the bhava to the Ghazals the range is both varied and vast. Though essentially seen in its solo form, Kathak in its Natya aspects shares a large corpus of the Rasalilas of Brindavan. Its journey from the Hindu temples to the courts of the Mughals is quite fascinating and the various elements it has imbibed over the different periods in history have given Kathak an equisite character. The Persian influence, the patronage of the Muslim kings, the flowering of the two main gharanas (schools), the Jaipur and the Lucknow, and the contribution of the Maharaj Brothers, the famous descendants of Kalka-Bindadin, viz.; Acchan Maharaj, Shambhu Maharaj, Lacchu Maharaj and Birju Maharaj, the great gurus of Jaipur like Jailalji and Sunder Prasadji portray Kathak as it has developed in recent times. Whereas the Choreographic attempts by Madame Menaka and later on by Birju Maharaj and Kumudini Lakhia provide a perspective for viewing Kathak in its many-faceted forms. The footwork, the nritta pieces like tode, tukde, parans, the improvisational aspects and the simple graceful gats and gat-nikas, the illusion of miniature paintings coming to life and many other aspects are vividly captured in this most comprehensive and thoroughl;y researched book on Kathak. It has an attractive section on the contemporary practitioners ranging from Birju Maharaj, Sitara Devi, Damayanti Joshi, Kumudini Lakhia, Rohini Bhate, Roshan Kumari, Gopi Krishna, Durgalal to the young exponents who carry forward the tradition in the present times. Lavishly illustrated with colour and black and white photographs and designed by Dolly Sahiar the many-splendoured beauty of Kathak is captured in this volume, which should appeal to the cognoscenti and lay readers alike.
MOLECULAR BIOTECHNOLOGY Therapeutic Applications and Strategies SUNIL MAULIK and SALIL D. PATEL Recombinant DNA technology, or genetic engineering, has revolutionized our understanding of life at the molecular level-giving us a detailed picture of the living cell's functions and spawning diverse biotechnologies that use molecules, cells, tissues, and even entire organisms. This introduction to molecular biotechnology is a practical, up-to-date guide to this rapidly growing field. Based on courses taught by the authors to biotechnology professionals, Molecular Biotechnology: Therapeutic Applications and Strategies applies the principles of modern biotechnology to advances and trends in the development of therapeutic strategies and approaches to disease prevention and intervention. By focusing on select applications and strategies, this volume exemplifies the convergence of biological, chemical, and informational advances in the discovery of novel targets and drugs. This multidisciplinary approach, essential to the development of commercial therapeutic molecules, includes carefully selected real-world examples from the pharmaceutical and biotechnology industries. Specific topics covered include: * Genome Based Medicine and the Human Genome Project * Human Gene Therapy * Combinatorial Chemistry * Rational Drug Design * Reengineering the Immune System User-friendly and organized for maximum understanding, Molecular Biotechnology: Therapeutic Applications and Strategies is an excellent text/reference for biotechnology professionals, researchers, physicians, students, managers, industry analysts, and investors interested in learning more about the field of molecular biotechnology.
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