Insects exhibit incredible physiological diversity, making them ideal model organisms for the purpose of this book. The authors draw together the central issues in physiology (nutrition, water balance, temperature, etc.), treating each in sufficient detail to give researchers a broad update in summary form, as well as senior students a feel for current work in the field. In addition, they examine patterns in physiological variation, and go on to explore the mechanisms underlying this variation as well as the ecological and evolutionary consequences.
Drs. Cohen, Powderly and Opal, three of the most-respected names in infectious disease medicine, lead a diverse team of international contributors to bring you the latest knowledge and best practices. Extensively updated, the fourth edition includes brand-new information on advances in diagnosis of infection; Hepatitis C; managing resistant bacterial infections; and many other timely topics. An abundance of photographs and illustrations; a practical, clinically-focused style; highly-templated organization; and robust interactive content combine to make this clinician-friendly resource the fastest and best place to find all of the authoritative, current information you need. - Hundreds of full-color photographs and figures provide unparalleled visual guidance. - Consistent chapter organization and colorful layouts make for quick searches. - Clinically-focused guidance from "Practice Points" demonstrates how to diagnose and treat complicated problems encountered in practice. - The "Syndromes by Body System", "HIV and AIDS", and "International Medicine" sections are designed to reflect how practicing specialists think when faced with a patient. - Sweeping updates include new or revised chapters on: - Hepatitis C and antivirals - Fungal infection and newer antifungals - Microbiome and infectious diseases as well as advances in diagnosis of infection; Clostridium difficile epidemiology; infection control in the ICU setting; Chlamydia trachomatis infection; acquired syndromes associated with autoantibodies to cytokines;; management of multidrug resistant pathogens; probiotics, polymyxins, and the pathway to developing new antibiotics - HIV including HIV and aging, antiretroviral therapy in developing countries, and cure for HIV. - Online Antimicrobial pharmacokinetics mannequin, as well an all new HIV medicine mannequin are a useful visual source of treatment information
Comprehensive and lavishly illustrated, McKee's Pathology of the Skin, 5th Edition, is your reference of choice for up-to-date, authoritative information on dermatopathology. You'll find clinical guidance from internationally renowned experts along with details on etiology, pathogenesis, histopathology, and differential diagnosis – making this unique reference unparalleled in its wealth of clinical and histopathological material. The 5th Edition of this classic text is a must-have resource for practicing dermatopathologists and general pathologists who sign out skin biopsies. - Covers pathological aspects of skin diseases in addition to providing superb descriptions and illustrations of their clinical manifestations – the only available reference with this unique combination of features. - Integrates dermatopathology, clinical correlations, and clinical photographs throughout, and features bulleted lists of clinical features and differential diagnosis tables for easy reference. - Contains more than 5,000 superb histopathologic and clinical illustrations that demonstrate the range of histologic manifestations. - Brings you fully up to date with key molecular aspects of disease, the capabilities and limitations of molecular diagnostics, and targeted/personalized medicine. - Features up-to-date information on biologics, drug eruptions, and other developments in therapeutics. - Helps you stay current with the latest diagnostic tumor markers and other new developments in immunohistochemistry. - Includes a completely revised chapter on cutaneous lymphoma that reflects recent WHO-EORTC classification changes, as well as new coverage of sentinel lymph node biopsy for melanoma. - Shares the knowledge of the main editor Dr. J. Eduardo Calonje, along with co-editors Thomas Brenn, and Alexander Lazar, and new co-editor Steven D. Billings who offers expertise on both dermatopathology and soft tissue tumors. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
Announcing the second volume of DeVita, Lawrence and Rosenberg's groundbreaking series, Cancer: Principles & Practice of Oncology—Annual Advances in Oncology. This series of annual volumes focuses on the most significant changes in oncologic research and practice that have taken place during the preceding year. Each volume identifies scientific and clinical areas in oncology that are rapidly changing and show a high potential for affecting the management of cancer patients in the future. These areas may reflect current controversies in oncology and every effort is made to provide clear direction for the practicing oncologist.
Now more than ever, doctors are being targeted by government prosecutors and whistleblowers challenging the legality of their relationships with drug and device companies. With reputations at stake and the risk of civil and criminal liability, it is incumbent upon doctors to protect themselves. Managing Relationships with Industry: A Physician's Compliance Manual is an indispensable resource for doctors, professional societies, academic medical centers, community hospitals, and group practices struggling to understand the ever changing law and ethical standards on interactions with pharmaceutical and device companies. It is the first comprehensive summary of the law and ethics on physician relationships with industry written for the physician. Authored by a former state Attorney General, Harvard Medical School Professor, health care lawyer and professor of ethics, Managing Relationships approaches the topic from a balanced and reasoned perspective adding to the on-going national dialogue and debate on the proper limits to medicine's relationship with industry. - The first complete and up-to-date summary and analysis of the law and ethics on physician-industry relationships - Focuses on major enforcement actions and whistleblower lawsuits and the lessons learned for physicians - Provides options and guidance for maintaining compliant relationships and avoiding traps for the unwary - Covers both drug and device company relationships - Summarizes the types of industry relationships that are necessary and productive and those that are harmful and abusive - Details the law and ethics for each type of relationship including gifts, off-label uses and marketing, CME, speaker's bureaus, free samples, grants, consulting arrangements, etc. - Includes sample contracts for permissible consulting and CME speaker engagements
Pharmacology and Physiology in Anesthetic Practice is a comprehensive review of how anesthetic drugs work in the human body. This text has long been required reading for anesthesia residents and student nurse anesthetists. This title provides foundational content in the field of anesthesiology. Understanding and applying the concepts explained in this text are crucial to competence as an anesthesiologist.
DeVita, Hellman, and Rosenberg's Cancer: Principles & Practice of Oncology, 10th edition has garnered universal acclaim as the world’s definitive, standard-setting oncology reference. More than 400 respected luminaries explore today’s most effective strategies for managing every type of cancer by stage of presentation - discussing the role of all appropriate therapeutic modalities as well as combined-modality treatments. This multidisciplinary approach will help your cancer team collaboratively face the toughest clinical challenges and provide the best possible care for every cancer patient. Access the complete contents online or on your mobile device, with quarterly updates reflecting late-breaking developments in cancer care, free for the first year on LWW Health Library. Take full advantage of the latest advances with brand-new chapters on Hallmarks of Cancer, Molecular Methods in Cancer, Oncogenic Viruses, Cancer Screening, and new sections on Genetic testing and counseling for cancer, plus comprehensive updates throughout – including coverage of the newest biologic therapies. Make optimal, well-coordinated use of all appropriate therapies with balanced, multidisciplinary advice from a surgeon, a medical oncologist, and a radiation oncologist in each major treatment chapter. Review the latest molecular biology knowledge for each type of cancer and its implications for improved management. Make the best decisions on cancer screening and prevention, palliative care, supportive oncology, and quality-of-life issues
The standard-setting text in oncology for 40 years, DeVita, Hellman and Rosenberg’s Cancer: Principles and Practice of Oncology, 12th Edition, provides authoritative guidance and strategies for managing every type of cancer by stage and presentation. Drs. Vincent T. DeVita, Jr., Theodore S. Lawrence, and Steven A. Rosenberg oversee an outstanding team of expert contributing authors who keep you up to date and fully informed in this fast-changing field. This award-winning reference is also continually updated on Health Library and VitalSource platforms for the life of the edition.
Both pain and addiction are tremendous public health problems. Practitioners of every stripe say that they learned precious little about pain or addiction in their training and readily admit that instruction on the interface of pain and addiction is nonexistent. The recent problem of prescription drug abuse has only served to highlight the fact that these two worlds need unificationthose who treat pain must be informed about the risks of controlled substances and those who treat addiction need to better and more fully understand their benefits. Nowhere is the pooled knowledge of pain management and addiction medicine brought together to allow for a greater appreciation of the risks of addiction when treating people with pain and the pain problems of those with chemical dependency. This major new volume brings this vast knowledge base together, presenting an array of perspectives by the foremost thought leaders at the interface of pain and chemical dependency, and is the most comprehensive resource on the subject to date. There have been an increasing number of seminars devoted to this topic and a new society, The International Society on Pain and Chemical Dependency, has recently been formed, and this volume is destined to become the classic text on this multidisciplinary subject. It will appeal to anesthesiologists, neurologists, rehab physicians, palliative care staff, pain center physicians, and psychologists.
A guide to "when to" and "what to" rather than "how to," this book provides evidence-based surgical reviews to provide credible answers to age-old surgical management questions. The management issues presented are oriented toward interventions and use evidence-based techniques to assess the safety and efficacy of new treatments and rehabilitative or preventative interventions. Each chapter is organized around the key questions essential to delineating the current status of evidence related to the subject reviewed. Publications from the past decade are cited that provide Level I and II evidence using the Oxford scale. Throughout Elective General Surgery, careful assessment of the validity of intervention studies and the strength of the evidence that they provide underlies the choices of cited publications. The information presented in this volume guides the scientific surgeon in providing state-of-the-art care and in optimizing the use of medical resources without losing sight of the need to address the unique needs of individual patients.
Selected from the world’s leading comprehensive cancer textbook, this tightly focused resource provides you with the practical, cutting-edge information you need to provide the best cancer care to each patient. Lymphomas and Leukemias: From Cancer: Principles & Practice of Oncology, 10th Edition, offers a complete and balanced view of this rapidly changing field, meeting the needs of oncology/hematology practitioners, fellows, and others who need an in-depth understanding of leukemias and lymphomas. The print reference gives you the solid, dependable guidance you have come to expect from this outstanding title, and the Inkling version features new quarterly updates written by a team of experts selected by the authors. Delivers focused, comprehensive information on leukemias and lymphomas drawn from the world’s leading cancer textbook, DeVita, Hellman, and Rosenberg’s Cancer: Principles & Practice of Oncology. Covers the full range of adult lymphomas and leukemias, including the molecular biology of lymphomas and acute and chronic leukemias; Hodgkin’s lymphoma; non-Hodgkin’s lymphoma; cutaneous lymphomas; management of acute and chronic leukemias, future directions and new treatments; myelodysplastic syndromes; plasma cell neoplasms; and more. Includes comprehensive information on leukemias and lymphomas of childhood, including supportive, long-term, palliative, and hospice care. Discusses in detail the growing importance of prevention and screening, giving you the understanding you need to improve your patients’ chances for a healthier, cancer-free life. Explains how the latest developments in biologic therapy apply to leukemias and lymphomas. Provides exhaustive coverage of combined modality cancer treatment, helping you determine when and how to integrate modalities in patient treatment. Ensures that you are fully up to date thanks to easy, mobile access to quarterly updates.
Consultations of Gastroenterology practitioners are frequently sought for many complex issues relating to acute and chronic liver disease. Many of the disease entities are uncommon and complicated in scope. Liver disease may occur in the setting of other chronic medical conditions and involve other organ systems, with recommendations for diagnostic strategies and therapeutic approaches somewhat challenging. Serious consequences are often the rule with misdiagnosed or inadequately treated liver disease. Dr. Flamm has provided a framework for approaching consultation for common liver-related problems for the gastroenterology practitioner. Articles are devoted to the following topics: Common Findings and Interpretation for the Clinician; Genetic Testing in Liver Disease: What to Order and When; Acute Liver Failure; Liver Disease in Oncology Patients; Primary Sclerosing Cholangitis: What the Gastroenterologist/Hepatologist Needs to Know; An Update on the Treatment and Follow up of Patients with PBC; Wilson’s Disease: Diagnosis, Treatment, and Follow Up; Follow Up of the Post-Liver Transplantation Patient: A Primer for the Practicing Gastroenterologist; Liver Disease in Patients on Total Parenteral Nutrition; Treatment Strategies in NAFLD: What’s Coming; Resistance Testing in Chronic HCV; and HCV genotype 3: Treatment Approach and Natural History.
Fetal & Neonatal Physiology provides neonatologist fellows and physicians with the essential information they need to effectively diagnose, treat, and manage sick and premature infants. Fully comprehensive, this resource continues to serve as an excellent reference tool, focusing on the basic science needed for exam preparation and the key information required for full-time practice. The 5th edition is the most substantially updated and revised edition ever. In the 5 years since the last edition published, there have been thousands of publications on various aspects of development of health and disease; Fetal and Neonatal Physiology synthesizes this knowledge into definitive guidance for today's busy practitioner. Offers definitive guidance on how to effectively manage the many health problems seen in newborn and premature infants. Chapters devoted to clinical correlation help explain the implications of fetal and neonatal physiology. Allows you to apply the latest insights on genetic therapy, intrauterine infections, brain protection and neuroimaging, and much more. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, images, and references from the book on a variety of devices. Features a fantastic new 4-color design with 1,000 illustrations, 170+ chapters, and over 350 contributors. 16 new chapters cover such hot topics as Epigenetics; Placental Function in Intrauterine Growth Restriction; Regulation of Pulmonary Circulation; The Developing Microbiome of the Fetus and Newborn; Hereditary Contribution to Neonatal Hyperbilirubinemia; Mechanistic Aspects of Phototherapy for Neonatal Hyperbilirubinemia; Cerebellar Development; Pathophysiology of Neonatal Sepsis; Pathophysiology of Persistent Pulmonary Hypertension of the Newborn; Pathophysiology of Meconium Aspiration Syndrome; Pathophysiology of Ventilator Dependent Infants; Pathophysiology of Hypoxic-Ischemic Brain Injury; Pathophysiology of Neonatal White Matter Injury; Pathophysiology of Meningitis; Pathophysiology of Preeclampsia; and Pathophysiology of Chorioamnionitis. New Pathophysiology of Neonatal Diseases section highlights every process associated with a disease or injury, all in one place. In-depth information, combined with end-of-chapter summaries, enables deep or quick use of the text.
Rothman-Simeone The Spine helps you achieve optimal outcomes in the clinical practice of spine surgery in adults and children. Drs. Harry N. Herkowitz, Steven R. Garfin, Frank J. Eismont, Gordon R. Bell, Richard Balderston, and an internationally diverse group of authorities help you keep up with the fast-paced field and get the best results from state-of-the-art treatments and surgical techniques, such as spinal arthroplasty and the latest spinal implants and equipment. An all-new full-color design and surgical videos online at www.expertconsult.com make this classic text more invaluable than ever before. Get the best results from the full range of both surgical and non-surgical treatment approaches with guidance from the world’s most trusted authorities in orthopaedic spine surgery. Find important information quickly through pearls, pitfalls, and key points that highlight critical points. Watch experts perform key techniques in real time with videos, on DVD and online, demonstrating minimally invasive surgery: SED procedure; thorascopic techniques; lumbar discectomy; pedicle subtraction osteotomy (PSO); C1, C2 fusion; intradural tumor; cervical laminoforaminoty; and much more. Apply the newest developments in the field thanks to expert advice on minimally invasive surgery, spinal arthroplasty and the latest spinal implants and equipments. See procedures clearly through an all new full-color design with 2300 color photographs and illustrations placed in context. Access the fully searchable contents of text online at www.expertconsult.com.
Get comprehensive, practical coverage of both surgical and non-surgical treatment approaches from the world's most trusted authorities in spine surgery and care. Rothman-Simeone and Herkowitz's The Spine, 7th Edition, edited by Drs. Steven R. Garfin, Frank J. Eismont, Gordon R. Bell, Jeffrey S. Fischgrund, and Christopher M. Bono, presents state-of-the-art techniques helping you apply today's newest developments in your practice. - Highlights critical information through the use of pearls, pitfalls, and key points throughout the text, as well as more than 2,300 full-color photographs and illustrations. - Offers a newly revised, streamlined format that makes it easier than ever to find the information you need. - Contains new chapters on the clinical relevance of finite element modeling and SI joint surgery. - Includes an expanded section on minimally invasive spine surgery, including recent developments and future directions. - Provides the latest evidence-based research from high-quality studies, including new randomized controlled trials for lumbar stenosis, surgery, fusion, and injections. - Presents the knowledge and expertise of new international contributors, as well as new editorial leadership from Dr. Steven Garfin. - Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
The premier reference in obstetrics for more than a century – now even more relevant to today's practice Williams Obstetrics is the most detailed, comprehensive, and rigorously referenced text on the subject. Written by an author team from the world-renowned Parkland Hospital, the hallmarks of this classic are its thoroughness, scientific basis, and practical applicability for the obstetrician at the bedside. This edition of Williams Obstetrics continues to emphasize the scientific-based underpinnings and evidence-based practices of the specialty. This is accomplished by using incorporating more than 3,000 new literature citations and guidelines from the most trusted professional and academic organizations. One of the important features of the twenty-fourth edition is a greater focus on the fetus as a patient and an expanded discussion of fetal diagnosis and therapy. This is complemented by more than 100 new sonographic and MR images of common fetal abnormalities. A new reorganization of the text enables the book to highlight more effectively the myriad disorders that may complicate pregnancy. Williams Obstetrics provides a convenient, clinically relevant text of value to the busy practitioner. The book summarizes important new data that has influenced evidence-based management to improve pregnancy outcomes. Much of this data is conveniently distilled into newly created tables and diagnostic and treatment algorithms. During discussion, numerous sources are cited to provide evidence-based options for patient management. Additionally, nearly 900 images complement the text, many of which are new or enhanced. These include sonograms, MR images, photographs, diagrams, and graphs. This edition of Williams Obstetrics continues to provide clinicians with everything they need to know about the practice of obstetrics with a level of authority and quality of presentation not found in any other resource.
The leading obstetrics reference for more than a century -- now in full-color and with a greater emphasis on evidence-based practice Written by a team of expert authors from world-renowned Parkland Hospital, this rigorously referenced, landmark resource tells you everything you need to know about the practice of obstetrics in a unified, consistent tone not found in other texts. For decades, ob-gyn practitioners and residents have hailed the book for its thoroughness, scientific orientation, and practical applicability at the bedside. Williams Obstetrics is reinforced throughout by a timely emphasis on evidence-based medicine, supported by state-of-the-art ultrasound images and original illustrations. The book's comprehensive coverage begins with an incisive look at maternal anatomy and physiology, and fetal growth and development. The text then progresses to the antepartum period, labor and delivery, the fetus and newborn, the peurperium period, obstetric complications, and medical and surgical complications. New to this Edition 1,100 brand-new, precisely rendered full-color illustrations Evidence-based medicine is highlighted in the text through the use of icons, better familiarizing you with the latest clinical guidelines and standards of care Greater use of headings and subheadings to quickly lead you to the content you need Improved algorithms and tables clearly and concisely present Class I evidence for diagnosis and treatment In-depth coverage of abnormal obstetrics -- from obstetrical hemorrhage and preterm birth, to reproductive tract abnormalities -- provides the most clinically relevant perspectives in this pivotal area
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