This issue provides important updates on the management of disorders of the anorectum and pelvic floor. Expert authors provide information on hemorrhoidal issues, anorectal anatomy and imaging techniques, fissure and anal stenosis, rectal prolapse, and anal abscess and fistula. Other articles are devoted to sexually transmitted and infectious diseases, treatment of radiation proctitis, and pruiritis ani. Readers will come away with a full understanding of the current strategies for diagnosis and management of these disorders.
Master Techniques in General Surgery: Colon and Rectal Surgery: Anorectal Operations is a volume in a series that presents common and advanced procedures in the major subspecialities of general surgery. The series is overseen by Josef F. Fischer, MD, editor of the classic two-volume reference Mastery of Surgery. Master Techniques in General Surgery: Colon and Rectal Surgery: Anorectal Operations is written by acknowledged master surgeons, emphasizes surgical procedures, and is lavishly illustrated with original full-color drawings. The contributors fully explain their preferred techniques in step-by-step, thoroughly illustrated detail, assess indications and contraindications, offer guidelines on preoperative planning, and discuss outcomes, complications, and follow-up. Coverage includes hemorrhoidectomies, anal fistula and sphincter procedures, procedures for perineal prolapse and excision of rectal carcinoma, among others. A companion website will offer fully searchable content of the book, an image bank, and procedural videos.
Monoclonal antibodies (MAbs) are currently the major class of protein bio therapeutic being developed by biotechnology and pharmaceutical companies. Monoclonal Antibodies discusses the challenges and issues revolving around development of a monoclonal antibody produced by recombinant DNA technology into a therapeutic agent.This book covers downstream processing which includes design of processes to manufacture the formulation, formulation design, fill and finish into closure systems and routes of administration. The characterization of the final drug product is covered where the use of biophysical methods combined with genetic engineering is used to understand the solution properties of the formulation. The latter has become very important since many indications such as arthritis and asthma require the development of formulations for subcutaneous delivery (SC). The development of formulations for IV delivery is also important and comes with a different set of challenges. The challenges and strategies that can overcome these limitations are discussed in this book, starting with an introduction to these issues, followed by chapters detailing strategies to deal with them. Subsequent chapters explore the processing and storage of mAbs, development of delivery device technologies and conclude with a chapter on the future of mAbs in therapeutic remedies. - Discusses the challenges to develop MAbs for intravenous (IV) and subcutaneous delivery (SC) - Presents strategies to meet the challenges in development of MAbs for SC and IV administration - Discusses the use of biophysical analytical tools coupled with MAb engineering to understand what governs MAb properties at high concentration
Obstetrics: Normal and Problem Pregnancies: First South Asia Edition remains your go-to choice for authoritative guidance on managing today's obstetric patient. International experts put the latest knowledge in this specialty at your fingertips, with current and relevant information on everything from fetal origins of adult disease, to improving global maternal health, to important topics in day-to-day obstetric practice. Highly readable, well-illustrated, and easy to understand, this best-selling obstetrics reference is an ideal tool for residents and clinicians. • Sweeping updates appear throughout, including four new chapters: "Vaginal Birth After Cesarean Delivery," "Placenta Accreta," "Obesity," and "Improving Global Maternal Health: Challenges and Opportunities." • New Glossary presents the most frequently used key abbreviations for easy reference. • Expanded use of bolded statements and key points, as well as additional tables, flow diagrams, and bulleted lists, facilitates and enhances the mastery of each chapter. • More than 100 images in the chapter on ultrasound provide an important resource for normal and abnormal fetal anatomy. • Collective wisdom of global experts in the field is offered.
After 30 years, Obstetrics: Normal and Problem Pregnancies remains your go-to choice for authoritative guidance on managing today’s obstetric patient. International experts put the latest knowledge in this specialty at your fingertips, with current and relevant information on everything from fetal origins of adult disease, to improving global maternal health, to important topics in day-to-day obstetrical practice. Highly readable, well-illustrated, and easy to understand, this bestselling obstetrics reference is an ideal tool for residents and clinicians. Take advantage of the collective wisdom of global experts in the field, including two new editors— Drs. Vincenzo Berghella and William Grobman -- and nearly 30 new contributors. Gain a new perspective on a wide range of today's key issues - all evidence-based and easy to read. Sweeping updates throughout including four new chapters: ‘Vaginal Birth after Cesarean Delivery’; ‘Placenta Accreta’; ‘Obesity’; and ‘Improving Global Maternal Health: Challenges and Opportunities’ New Glossary of the most frequently used key abbreviations for easy reference Expanded use of bolded statements and key points as well as additional tables, flow diagrams, and bulleted lists facilitates and enhances the mastery of each chapter More than 100 images in the Obstetrical Ultrasound chapter provide an important resource for normal and abnormal fetal anatomy
Introduce your students to the important new features that the latest version of Microsoft Office has to offer with the focused approach found in Cable/Freund/Monk/Sebok/Starks/Vermaat's MICROSOFT Office 365 & OFFICE 2019 INTRODUCTORY. Part of the acclaimed Shelly Cashman Series, this edition continues the series' strong history of innovation with an enhanced learning approach designed to engage students, improve retention and prepare learners for success with Microsoft Office. A trademark step-by-step, screen-by-screen approach encourages students to expand their understanding of the software through experimentation, critical thought and personalization while also engaging them in real-world scenarios to reinforce critical skills to make them successful in their educational and professional careers. In addition, MindTap and updated SAM (Skills Assessment Manager) online resources are available to guide additional study and ensure successful results. Important Notice: Media content referenced within the product description or the product text may not be available in the ebook version.
Now you can combine strong computer concepts from the best-selling DISCOVERING COMPUTERS with proven step-by-step instruction on Microsoft Office 2016 in one convenient book. DISCOVERING COMPUTERS & MICROSOFT OFFICE 365 & OFFICE 2016: A FUNDAMENTAL COMBINED APPROACH delivers the best of the acclaimed Shelly Cashman Series in a single resource. As part of the Series that has effectively introduced computer skills to millions of students like you, this book encourages critical thought, personalization, and experimentation with the latest Microsoft Office 365 and Office2016 software. Updated and revised computer concepts content throughout this edition reflect the evolving needs of those learning computing today with an exclusive focus on the skills you need to be successful in college and beyond. Enhancements to the book and accompanying resources ensure DISCOVERING COMPUTERS & MICROSOFT OFFICE 2016 delivers today's most effective introduction to Microsoft Office 2016.
Discover how to fully utilize the latest version of Microsoft Office with the focused approach found in Shelly Cashman Series MICROSOFT OFFICE 365 & OFFICE 2016: INTERMEDIATE. This new edition is part of the acclaimed Shelly Cashman Series that has effectively introduced computer skills to millions of students like you. Shelly Cashman Series MICROSOFT OFFICE 365 & OFFICE 2016: INTERMEDIATE continues the Series' strong history of innovation with an enhanced learning approach designed to address your needs, no matter what your learning style. A trademark step-by-step, screen-by-screen approach helps expand your understanding of Microsoft Office 2016 through experimentation, critical thought, and personalization. This new edition delivers some of today's most effective educational materials specifically designed to capture your attention, improve retention, and prepare you for success in working with Microsoft Office 2016.
No matter what level of computer experience readers have, the practical, user-friendly Shelly Cashman Series MICROSOFT WINDOWS 10: COMPREHENSIVE can equip today’s learners with the skills and knowledge to effectively navigate and utilize Microsoft Windows 10. Part of the acclaimed Shelly Cashman Series, this book offers a trademark, step-by-step, screen-by-screen approach that encourages readers to expand their understanding of the Microsoft Windows 10 operating system through experimentation, exploration, and advanced planning. Proven hands-on features and accompanying online resources keep readers’ attention and prepare learners for future success in working with both MS Office and Windows 10. Important Notice: Media content referenced within the product description or the product text may not be available in the ebook version.
Discover how to utilize the most advanced features within the latest version of Microsoft Office with Shelly Cashman Series MICROSOFT OFFICE 365 & OFFICE 2016: ADVANCED. This new edition is part of the acclaimed Shelly Cashman Series that has effectively introduced computer skills to millions. Shelly Cashman Series MICROSOFT OFFICE 365 & OFFICE 2016: ADVANCED continues the Series’ strong history of innovation with an enhanced learning approach designed to address the varied learning styles of today’s readers. A trademark step-by-step, screen-by-screen approach helps readers expand their understanding of higher-level Microsoft Office 2016 skills through experimentation, critical thought, and personalization. This new edition promises to capture and hold readers’ attention, improve retention, and prepare readers for success in working with the most advanced aspects of Microsoft Office 2016. Important Notice: Media content referenced within the product description or the product text may not be available in the ebook version.
No matter what your depth or range of experience, the practical, user-friendly Shelly Cashman Series MICROSOFT WINDOWS 10: COMPREHENSIVE can equip you with the complete skills and thorough knowledge you need to effectively navigate and fully utilize Microsoft Windows 10. Part of the acclaimed Shelly Cashman Series, this book offers a trademark, step-by-step, screen-by-screen approach that encourages you to expand your understanding of the Microsoft Windows 10 operating system through experimentation, exploration, and advanced planning. You'll find proven, hands-on features and accompanying online resources specifically designed to keep your attention and prepare you for future success in working with MS Office and Windows.
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