Show Tunes fully chronicles the shows, songs, and careers of the major composers of the American musical theatre, from Jerome Kern's earliest interpolations to the latest hits on Broadway. Legendary composers like Gershwin, Rodgers, Porter, Berlin, Bernstein, and Sondheim have been joined by more recent songwriters like Stephen Schwartz, Stephen Flaherty, Michael John LaChiusa, and Adam Guettel. This majestic reference book covers their work, their innovations, their successes, and their failures. Show Tunes is simply the most comprehensive volume of its kind ever produced, and this newly revised and updated edition discusses almost 1,000 shows and 9,000 show tunes. The book has been called "a concise skeleton key to the Broadway musical" (Variety) and "a ground-breaking reference work with a difference" (Show Music)-or, as the Washington Post observed, "It makes you sing and dance all over your memory." The eagerly anticipated Fourth Edition, updated through May, 2009, features the entire theatrical output of forty of Broadway's leading composers, in addition to a wide selection of work by other songwriters. The listings include essential production data and statistics, the most extensive information available on published and recorded songs, and lively commentary on the shows, songs, and diverse careers. Based on meticulous research, the book also uncovers dozens of lost musicals-including shows that either closed out of town or were never headed for Broadway-and catalogs hundreds of previously unknown songs, including a number of musical gems that have been misplaced, cut, or forgotten. Informative, insightful, and provocative, Show Tunes is an essential guide for anyone interested in the American musical.
Laboratory Investigations in Molecular Biology presents well-tested protocols in molecular biology that are commonly used in currently active research labs. It is an ideal laboratory manual for college level courses in molecular biology. Because of the modular organization of the manual, laboratory courses can be assembled that would be ideal for science professionals, graduate students, undergraduate students and even advanced high school students in AP courses. The manual is also intended to be useful as a laboratory "bench reference". The experiments are designed to guide students through realistic research projects and to provide students with instruction in methods and approaches that can be immediately translated into research projects conducted in modern research laboratories. Although these experiments have been conducted and optimized over 20 years of teaching the New England Biolabs Molecular Biology Summer Workshops, they are real research projects, not "canned" experiments. Based on extensive teaching experience using these protocols, the authors have found that conducting these experiments as described in these protocols serves to effectively instruct students and science professions in the basic methods of molecular biology. An additional unique feature is that the protocols described in the manual are accompanied by available reagent kits that provide quality-tested, pre-packaged reagents to ensure the successful application of these protocols in a laboratory course setting.
Presents elements of clinical trial methods that are essential in planning, designing, conducting, analyzing, and interpreting clinical trials with the goal of improving the evidence derived from these important studies This Third Edition builds on the text’s reputation as a straightforward, detailed, and authoritative presentation of quantitative methods for clinical trials. Readers will encounter the principles of design for various types of clinical trials, and are then skillfully guided through the complete process of planning the experiment, assembling a study cohort, assessing data, and reporting results. Throughout the process, the author alerts readers to problems that may arise during the course of the trial and provides common sense solutions. All stages of therapeutic development are discussed in detail, and the methods are not restricted to a single clinical application area. The authors bases current revisions and updates on his own experience, classroom instruction, and feedback from teachers and medical and statistical professionals involved in clinical trials. The Third Edition greatly expands its coverage, ranging from statistical principles to new and provocative topics, including alternative medicine and ethics, middle development, comparative studies, and adaptive designs. At the same time, it offers more pragmatic advice for issues such as selecting outcomes, sample size, analysis, reporting, and handling allegations of misconduct. Readers familiar with the First and Second Editions will discover revamped exercise sets; an updated and extensive reference section; new material on endpoints and the developmental pipeline, among others; and revisions of numerous sections. In addition, this book: • Features accessible and broad coverage of statistical design methods—the crucial building blocks of clinical trials and medical research -- now complete with new chapters on overall development, middle development, comparative studies, and adaptive designs • Teaches readers to design clinical trials that produce valid qualitative results backed by rigorous statistical methods • Contains an introduction and summary in each chapter to reinforce key points • Includes discussion questions to stimulate critical thinking and help readers understand how they can apply their newfound knowledge • Provides extensive references to direct readers to the most recent literature, and there are numerous new or revised exercises throughout the book Clinical Trials: A Methodologic Perspective, Third Edition is a textbook accessible to advanced undergraduate students in the quantitative sciences, graduate students in public health and the life sciences, physicians training in clinical research methods, and biostatisticians and epidemiologists. This book is accompanied by downloadable files available below under the DOWNLOADS tab. These files include: MATHEMATICA program – A set of downloadable files that tracks the chapters, containing code pertaining to each. SAS PROGRAMS and DATA FILES used in the book. The following software programs, included in the downloadables, were developed by the author, Steven Piantadosi, M.D., Ph.D: RANDOMIZATION – This program generates treatment assignments for a clinical trial using blocked stratified randomization. CRM – Implements the continual reassessment methods for dose finding clinical trials. OPTIMAL – Calculates two-stage optimal phase II designs using the Simon method. POWER – This is a power and sample size program for clinical trials. Executables for installing these programs can also be found at https://risccweb.csmc.edu/biostats/. Steven Piantadosi, MD, PhD, is the Phase One Foundation Distinguished Chair and Director of the Samuel Oschin Cancer Institute, and Professor of Medicine at Cedars-Sinai Medical Center in Los Angeles, California. Dr. Piantadosi is one of the world’s leading experts in the design and analysis of clinical trials for cancer research. He has taught clinical trials methods extensively in formal courses and short venues. He has advised numerous academic programs and collaborations nationally regarding clinical trial design and conduct, and has served on external advisory boards for the National Institutes of Health and other prominent cancer programs and centers. The author of more than 260 peer-reviewed scientific articles, Dr. Piantadosi has published extensively on research results, clinical applications, and trial methodology. While his papers have contributed to many areas of oncology, he has also collaborated on diverse studies outside oncology including lung disease and degenerative neurological disease.
Enforcing Morality is written for scholars and graduate students working in the fields of philosophy, law and political theory. It provides both a critical overview of debates on the enforcement of morality and a defense of a distinctive position on the topic.
For Paine, Wollstonecraft, and Williams, the crisis in representation was actually a variety of representational crises. That they returned to the paradigms of the past to resolve the crisis signified that they were rewriting the Revolution within the textual space of the tradition they had originally opposed.
People who are themselves scheduled for surgery or whose family members are scheduled for surgery will be drawn to this book, which demystifies anesthesia. The author is an associate professor of anesthesia at the University of Pittsburgh and has written several anesthesia textbooks. He describes the various options for anesthesia, and explains the pros and cons"--Provided by publisher.
Covering the broad range of benign and malignant disorders that affect the hematopoietic system, Hematopathology, 3rd Edition, remains your #1 source of authoritative information in this fast-changing field. Edited by Dr. Elaine Jaffe and a team of globally renowned, expert co-editors, it offers a wealth of up-to-date information in an easily accessible format, equipping you to deliver more accurate and actionable pathology reports. Comprehensive in scope, this highly illustrated, practical text is a must-have resource for residents and practicing pathologists alike. - Helps you navigate the latest changes in the classification of hematolymphoid neoplasms, providing guidance for use of both the International Consensus Classification (ICC) and 5th edition of the WHO classification. - Incorporates the latest molecular/cytogenetic information, regarding newly recognized entities and the latest diagnostic criteria. - Provides you with today's most effective guidance in evaluating specimens from the lymph nodes, bone marrow, peripheral blood, and more, with authoritative information on the pathogenesis, clinical and pathologic diagnosis, and treatment for each. - Details the latest insights on the molecular biology of benign and malignant hematologic disorders. - Features more than 1,100 high-quality color images that mirror the findings you encounter in practice. - Uses an easy-to-navigate, templated format with standard headings in each chapter. - Includes information on disease progression and prognosis, helping you better understand the clinical implications of diagnosis. - Shares the knowledge and expertise of new editors, Drs. Lisa Rimsza, Attilio Orazi, and Steven Swerdlow, providing expertise in molecular diagnostics, bone marrow and lymph node biopsies.
The premier reference in obstetrics for more than a century – now even more relevant to today's practice Williams Obstetrics is the most detailed, comprehensive, and rigorously referenced text on the subject. Written by an author team from the world-renowned Parkland Hospital, the hallmarks of this classic are its thoroughness, scientific basis, and practical applicability for the obstetrician at the bedside. This edition of Williams Obstetrics continues to emphasize the scientific-based underpinnings and evidence-based practices of the specialty. This is accomplished by using incorporating more than 3,000 new literature citations and guidelines from the most trusted professional and academic organizations. One of the important features of the twenty-fourth edition is a greater focus on the fetus as a patient and an expanded discussion of fetal diagnosis and therapy. This is complemented by more than 100 new sonographic and MR images of common fetal abnormalities. A new reorganization of the text enables the book to highlight more effectively the myriad disorders that may complicate pregnancy. Williams Obstetrics provides a convenient, clinically relevant text of value to the busy practitioner. The book summarizes important new data that has influenced evidence-based management to improve pregnancy outcomes. Much of this data is conveniently distilled into newly created tables and diagnostic and treatment algorithms. During discussion, numerous sources are cited to provide evidence-based options for patient management. Additionally, nearly 900 images complement the text, many of which are new or enhanced. These include sonograms, MR images, photographs, diagrams, and graphs. This edition of Williams Obstetrics continues to provide clinicians with everything they need to know about the practice of obstetrics with a level of authority and quality of presentation not found in any other resource.
Offering a multifaceted, practical approach to the complex topic of clinical assessment, Practical Guide to the Assessment of Clinical Competence, 3rd Edition, is designed to help medical educators employ better assessment methods, tools, and models directly into their training programs. World-renowned editors and expert contributing authors provide hands-on, authoritative guidance on outcomes-based assessment in clinical education, presenting a well-organized, diverse combination of methods you can implement right away. This thoroughly revised edition is a valuable resource for developing, implementing, and sustaining effective systems for assessing clinical competence in medical school, residency, and fellowship programs. - Helps medical educators and administrators answer complex, ongoing, and critical questions in today's changing medical education system: Is this undergraduate or postgraduate medical student prepared and able to move to the next level of training? To be a competent and trusted physician? - Provides practical suggestions and assessment approaches that can be implemented immediately in your training program, tools that can be used to assess and measure clinical performance, overviews of key educational theories, and strengths and weaknesses of every method. - Covers assessment techniques, frameworks, high-quality assessment of clinical reasoning and procedural competence, psychometrics, and practical approaches to feedback. - Includes expanded coverage of fast-moving areas where concepts now have solid research and data that support practical ways to connect judgments of ability to outcomes—including work-based assessments, clinical competency committees, milestones and entrustable professional assessments (EPAs), and direct observation. - Offers examples of assessment instruments along with suggestions on how you can apply these methods and instruments in your own setting, as well as guidelines that apply across the medical education spectrum. - Includes online access to videos of medical interviewing scenarios and more, downloadable assessment tools, and detailed faculty guidelines. - An eBook version is included with purchase. The eBook allows you to access all of the text, figures, and references, with the ability to search, make notes and highlights, and have content read aloud.
A concise and updated review of prostate cancer pathologic diagnosis with emphasis on practical issues and recent developments in the field. Each chapter addresses the basic diagnostic features, differential diagnoses, pitfalls and ways to resolve the problem. Additionally, a brief introduction of prostate cancer screening, clinical management and treatment are summarized. Recent development of immunohistochemistry, molecular testing in the diagnosis, prognosis and treatment are also reviewed. Finally, current knowledge of molecular alteration of prostate cancer carcinogenesis and impact in diagnosis and treatment are discussed.
DeVita, Hellman, and Rosenberg's Cancer: Principles & Practice of Oncology, 10th edition has garnered universal acclaim as the world’s definitive, standard-setting oncology reference. More than 400 respected luminaries explore today’s most effective strategies for managing every type of cancer by stage of presentation - discussing the role of all appropriate therapeutic modalities as well as combined-modality treatments. This multidisciplinary approach will help your cancer team collaboratively face the toughest clinical challenges and provide the best possible care for every cancer patient. Access the complete contents online or on your mobile device, with quarterly updates reflecting late-breaking developments in cancer care, free for the first year on LWW Health Library. Take full advantage of the latest advances with brand-new chapters on Hallmarks of Cancer, Molecular Methods in Cancer, Oncogenic Viruses, Cancer Screening, and new sections on Genetic testing and counseling for cancer, plus comprehensive updates throughout – including coverage of the newest biologic therapies. Make optimal, well-coordinated use of all appropriate therapies with balanced, multidisciplinary advice from a surgeon, a medical oncologist, and a radiation oncologist in each major treatment chapter. Review the latest molecular biology knowledge for each type of cancer and its implications for improved management. Make the best decisions on cancer screening and prevention, palliative care, supportive oncology, and quality-of-life issues
Recent scientific advances have revolutionized cancer research and practice, creating a body of molecular biology information that is important to research scientists and clinical oncologists alike. Cancer: Principles and Practice of Oncology: Primer of the Molecular Biology of Cancer, 3rd Edition, keeps you up to date with all that’s new in this rapidly changing field. Derived from DeVita, Hellman, and Rosenberg’s Cancer: Principles and Practice of Oncology – widely regarded as the definitive clinical reference in oncology – the third edition of this popular Primer provides a single-volume, highly focused reference on every important frontier in the molecular biology of cancer.
Understand and apply the scientific advances that are revolutionizing cancer research and practice with Cancer: Principles and Practice of Oncology: Primer of the Molecular Biology of Cancer. Derived from DeVita, Hellman, and Rosenberg’s Cancer: Principles and Practice of Oncology – widely hailed as the definitive clinical reference in oncology – the second editon of this popular Primer focuses on the molecular biology information that is of critical importance to research scientists and clinical oncologists alike. Get up-to-date, dependable coverage of every important frontier in aspect of the molecular biology of cancer with contributions from a noteworthy roster of leading scientists and clinicians, featuring an updated version of the classic “Hallmarks of Cancer” by Hanahan and Weinberg See how molecular biology advances are impacting clinical practice with separate chapters on each of the 19 most common cancer types. Navigate the challenges and ethical dilemmas of cancer genetics with a thorough section chapters on genetic counseling and genetic testing.
Selected from the world’s leading comprehensive cancer textbook, this tightly focused resource provides you with the practical, cutting-edge information you need to provide the best cancer care to each patient. Lymphomas and Leukemias: From Cancer: Principles & Practice of Oncology, 10th Edition, offers a complete and balanced view of this rapidly changing field, meeting the needs of oncology/hematology practitioners, fellows, and others who need an in-depth understanding of leukemias and lymphomas. The print reference gives you the solid, dependable guidance you have come to expect from this outstanding title, and the Inkling version features new quarterly updates written by a team of experts selected by the authors. Delivers focused, comprehensive information on leukemias and lymphomas drawn from the world’s leading cancer textbook, DeVita, Hellman, and Rosenberg’s Cancer: Principles & Practice of Oncology. Covers the full range of adult lymphomas and leukemias, including the molecular biology of lymphomas and acute and chronic leukemias; Hodgkin’s lymphoma; non-Hodgkin’s lymphoma; cutaneous lymphomas; management of acute and chronic leukemias, future directions and new treatments; myelodysplastic syndromes; plasma cell neoplasms; and more. Includes comprehensive information on leukemias and lymphomas of childhood, including supportive, long-term, palliative, and hospice care. Discusses in detail the growing importance of prevention and screening, giving you the understanding you need to improve your patients’ chances for a healthier, cancer-free life. Explains how the latest developments in biologic therapy apply to leukemias and lymphomas. Provides exhaustive coverage of combined modality cancer treatment, helping you determine when and how to integrate modalities in patient treatment. Ensures that you are fully up to date thanks to easy, mobile access to quarterly updates.
Selected from the world’s leading comprehensive cancer textbook, this tightly focused resource provides you with the practical, cutting-edge information you need to provide the best cancer care to each patient. Cancer of the Breast: Cancer: Principles & Practice of Oncology, 10th Edition, offers a comprehensive and balanced view of this rapidly changing field, meeting the needs of oncology practitioners, fellows, and others who need an in-depth understanding of breast cancer. The print reference gives you the solid, dependable guidance you’ve come to expect from this outstanding title, and the Inkling version features new quarterly updates written by a team of experts selected by the authors.
Selected from the world’s leading comprehensive cancer textbook, this tightly focused resource provides you with the practical, cutting-edge information you need to provide the best cancer care to each patient. Colon and Other Gastrointestinal Cancers: Cancer: Principles & Practice of Oncology, 10th Edition, offers a comprehensive and balanced view of this rapidly changing field, meeting the needs of oncology practitioners, fellows, and others who need an in-depth understanding of colon and GI cancer. The print reference gives you the solid, dependable guidance you’ve come to expect from this outstanding title, and the Inkling version features new quarterly updates written by a team of experts selected by the authors.
Fetal and Neonatal Physiology, edited by Drs. Polin, Fox, and Abman, focuses on physiologic developments of the fetus and newborn and their impact on the clinical practice of neonatology. A must for practice, this 4th edition brings you the latest information on genetic therapy, intrauterine infections, brain protection and neuroimaging, and much more. Gain a comprehensive, state-of-the-art understanding of normal and abnormal physiology, and its relationship to disease in the fetus and newborn premature infant, from Dr. Richard Polin and other acknowledged worldwide leaders in the field. Understand the implications of fetal and neonatal physiology through chapters devoted to clinical correlation. Apply the latest insights on genetic therapy, intrauterine infections, brain protection and neuroimaging, and much more. Effectively manage the consequences of intrauterine infections with three new chapters covering intrauterine infection and preterm birth, intrauterine infection and brain injury, and intrauterine infection and chronic lung disease.
Fetal and Neonatal Physiology, edited by Drs. Polin, Fox, and Abman, focuses on physiologic developments of the fetus and newborn and their impact on the clinical practice of neonatology. A must for practice, this 4th edition brings you the latest information on genetic therapy, intrauterine infections, brain protection and neuroimaging, and much more. You'll also have easy access to the complete contents and illustrations online at expertconsult.com. Gain a comprehensive, state-of-the-art understanding of normal and abnormal physiology, and its relationship to disease in the fetus and newborn premature infant, from Dr. Richard Polin and other acknowledged worldwide leaders in the field. Understand the implications of fetal and neonatal physiology through chapters devoted to clinical correlation. Apply the latest insights on genetic therapy, intrauterine infections, brain protection and neuroimaging, and much more. Effectively manage the consequences of intrauterine infections with three new chapters covering intrauterine infection and preterm birth, intrauterine infection and brain injury, and intrauterine infection and chronic lung disease. Access the complete contents and illustrations online at expertconsult.com - fully searchable! Get the latest developments and a full understanding of the distinct physiology of the fetus and newborn so you can treat and manage sick newborns and preemies.
China’s emergence in Africa is the most significant development for the continent since at least the end of the Cold War. Of the permanent members of the UN Security Council, China is also the largest contributor in terms of troop numbers to United Nations Peacekeeping Operations (UNPKO). While China’s potential to be a force for change in Africa is undeniable, there are wildly varied and sometimes unrealistic expectations in both the West and Africa of China’s role in Africa. A more detailed and nuanced understanding of Chinese motivations in its African engagement is necessary, in order to work effectively with China for African peace, security and development. With Liberia, Darfur and South Sudan as case studies, Kuo comprehensively examines the "Chinese peace" and places it within the context of the liberal peace debate. He does so using primary sources translated from the original Chinese, as well as interviews conducted in Mandarin with Chinese policymakers, academics, diplomats as well as Chinese company managers and businessmen working in Liberia and South Sudan. He also traces and analyses the Chinese discourse of peace, from traditional Chinese political philosophy, through Mao Zedong and Deng Xiaoping to post-reform and the Xi Jinping era.
Activist New York surveys New York City's long history of social activism from the 1650's to the 2010's. Bringing these passionate histories alive, Activist New York is a visual exploration of these movements, serving as a companion book to the highly-praised Museum of the City of New York exhibition of the same name. New York's primacy as a metropolis of commerce, finance, industry, media, and ethnic diversity has given it a unique and powerfully influential role in the history of American and global activism. Steven H. Jaffe explores how New York's evolving identities as an incubator and battleground for activists have made it a "machine for change." In responding to the city as a site of slavery, immigrant entry, labor conflicts, and wealth disparity, New Yorkers have repeatedly challenged the status quo. Activist New York brings to life the characters who make up these vibrant histories, including David Ruggles, an African American shopkeeper who helped enslaved fugitives on the city's Underground Railroad during the 1830s; Clara Lemlich, a Ukrainian Jewish immigrant who helped spark the 1909 "Uprising of 20,000" that forever changed labor relations in the city's booming garment industry; and Craig Rodwell, Karla Jay, and others who forged a Gay Liberation movement both before and after the Stonewall Riot of June 1969. Permanent exhibition: Puffin Foundation Gallery, Museum of the City of New York, USA.
Robert Schaeffer and Douglas West are best friends living in Oklahoma in 1963when they discover that they both sense a calling to become ministers in a mainline Christian denomination. But from seminary and their early years in ministry to their golden years looking back on what it takes to lead a congregation, a stimulating, sometimes puzzling, yet often inspirational world of theological controversies and congregational concerns would unfold for these two men of God. A Church Wide Enough for Everyone follows these two men on their journey to demonstrate the continuing relevance of the Christian faith in a postmodern world. After moving to Berkeley, California, to attend college and seminary, they have little time to ponder the vast social changes taking place before they immediately enter into intensive critical study of the Bible and Christian theology. And as Robert is then thrust into the ordained ministry with his wife, Faye, both men must in their own ways face the political, cultural, and ideological pressures of each passing decade, responding to challenges from both within the church and from outsiders. Are mainline churchesand Christian theologydead? Or might they be revitalized in the current century? A Church Wide Enough for Everyone and the inspired journeys of two ministers offers a window into how this revitalization and new understanding is possible.
Psychology: from inquiry to understanding 2e continues its commitment to emphasise the importance of scientific-thinking skills. It teaches students how to test their assumptions, and motivates them to use scientific thinking skills to better understand the field of psychology in their everyday lives. With leading classic and contemporary research from both Australia and abroad and referencing DSM-5, students will understand the global nature of psychology in the context of Australia’s cultural landscape.
This wide-ranging study of the Pacific Islands provides a dynamic and provocative account of the peopling of the Pacific, and its broad impact on world history. Spanning over 50,000 years of human presence in an area which comprises one-third of our planet – Melanesia, Micronesia and Polynesia – the narrative follows the development of the region, from New Guinea's earliest settlement to the creation of the modern Pacific states. Thoroughly revised and updated in light of the most recent scholarship, the second edition includes: • an overview of the events and developments in the Pacific Islands over the last decade • coverage of the latest archaeological discoveries • several new maps • an updated and expanded bibliography Steven Roger Fischer's unique text provides a highly accessible and invaluable introduction to the history of an area which is currently emerging as pivotal in international affairs. A History of the Pacific Islands traces the human history of nearly one-third of the globe over a fifty-thousand year span. This is history on a grand scale, taking the islands of Melanesia, Micronesia and Polynesia from prehistoric culture to the present day through a skilful interpretation of scholarship in the field. Fischer's familiarity with work in archaeology and anthropology as well as in history enriches the text, making this a book with wide appeal for students and general readers.
Thousands of African men, women, and children worked on European-owned tobacco farms in colonial Zimbabwe from 1890 to 1945. Contrary to some commonly held notions, these people were not mere bystanders as European capitalism penetrated into Zimbabwe, but helped to shape the work and the living conditions they encountered as they entered wage employment. Steven Rubert's fine study draws on a rich variety of sources to illuminate the lives of these workers. The central focus of the study is the organization of workers' compounds, the social relationships there, and the labor of women and children, paid and unpaid. Rubert's findings indicate the beginnings of a moral economy on the tobacco farms prior to 1945.
A brilliant, witty, and altogether satisfying book." — New York Times Book Review The classic work on the development of human language by the world’s leading expert on language and the mind In The Language Instinct, the world's expert on language and mind lucidly explains everything you always wanted to know about language: how it works, how children learn it, how it changes, how the brain computes it, and how it evolved. With deft use of examples of humor and wordplay, Steven Pinker weaves our vast knowledge of language into a compelling story: language is a human instinct, wired into our brains by evolution. The Language Instinct received the William James Book Prize from the American Psychological Association and the Public Interest Award from the Linguistics Society of America. This edition includes an update on advances in the science of language since The Language Instinct was first published.
This unique reference presents 59 biographies of people who were key to the sea services being reasonably prepared to fight the Japanese Empire when the Second World War broke out, and whose advanced work proved crucial. These intelligence pioneers invented techniques, procedures, and equipment from scratch, not only allowing the United States to hold its own in the Pacific despite the loss of most of its Fleet at Pearl Harbor, but also laying the foundation of today’s intelligence methods and agencies. One-hundred years ago, in what was clearly an unsophisticated pre-information era, naval intelligence (and foreign intelligence in general) existed in rudimentary forms almost incomprehensible to us today. Founded in 1882, the U.S. Office of Naval Intelligence (ONI)—the modern world’s “oldest continuously operating intelligence agency”—functioned for at least its first forty years with low manning, small budgets, low priority, and no prestige. The navy’s early steps into communications intelligence (COMINT), which included activities such as radio interception, radio traffic analysis, and cryptology, came with the 1916 establishment of the Code and Signals Section within the navy’s Division of Communications and with the 1924 creation of the “Research Desk” as part of the Section. Like ONI, this COMINT organization suffered from low budgets, manning, priority, and prestige. The dictionary focuses on these pioneers, many of whom went on, even after World War II, to important positions in the Navy, the State Department, the Armed Forces Security Agency, the National Security Agency, and the Central Intelligence Agency. It reveals the work and innovations of well and lesser-known individuals who created the foundations of today’s intelligence apparatus and analysis.
Regulation of Securities: SEC Answer Book, Fourth Edition is your complete guide to understanding and complying with the day-to-day requirements of the federal securities laws that affect all public companies. Using a question-and-answer format similar to that which the SEC has embraced, this valuable desk reference provides concise, understandable answers to the most frequently asked compliance questions, and ready access to key statutes, regulations, and court decisions. Designed for both beginners and seasoned professionals, the volume contains approximately 1,400 pages organized in 23 self-contained chapters. Each chapter covers the basics before moving into the nuanced details, meeting the needs of those who seek a general understanding of a topic as well as those grappling directly with critical issues. Twice-yearly supplements keep the book current in this rapidly evolving field. Whether you are a lawyer, accountant, corporate executive, director or investor, youand’ll be able to quickly find concise answers to essential questions about the Dodd-Frank Act, Exchange Act registration and reporting, executive compensation disclosure, derivatives disclosure, managementand’s discussion and analysis, audit committee responsibilities, Sarbanes-Oxley, electronic filing, interactive financial data, tender offers, proxy solicitations, insider trading, going private transactions, shareholdersand’ rights, SEC investigations, criminal enforcement, securities class actions, and much more!
All new medicines and devices undergo early phase trials to assess, interpret and better understand their efficacy, tolerability and safety. An Introduction to Statistics in Early Phase Trials describes the practical design and analysis of these important early phase clinical trials and provides the crucial statistical basis for their interpretation. It clearly and concisely provides an overview of the most common types of trials undertaken in early phase clinical research and explains the different methodologies used. The impact of statistical technologies on clinical development and the statistical and methodological basis for making clinical and investment decisions are also explained. Conveys key ideas in a concise manner understandable by non-statisticians Explains how to optimise designs in a constrained or fixed resource setting Discusses decision making criteria at the end of Phase II trials Highlights practical day-to-day issues and reporting of early phase trials An Introduction to Statistics in Early Phase Trials is an essential guide for all researchers working in early phase clinical trial development, from clinical pharmacologists and pharmacokineticists through to clinical investigators and medical statisticians. It is also a valuable reference for teachers and students of pharmaceutical medicine learning about the design and analysis of clinical trials.
The cornerstone text on visual science – now more clinically relevant than ever SELF-ASSESSMENT QUIZ IN EACH CHAPTER A Doody’s Core Title for 2021! Through five acclaimed editions, this trusted text has bridged the gap between basic visual science and clinical application. The Fifth Edition continues this mission with a more streamlined presentation and an even greater focus on clinical relevancy. Wide in scope, the book covers every clinically important aspect of visual science, including color vision and its defects, spatial vision, temporal aspects of vision, psychophysics, physiology, and development and maturation of the visual system. This edition has been dramatically enhanced, with all figures in beautiful full color and the addition of new clinical images (including color vision tests and fundus photographs). All chapters have been thoroughly revised to reflect the latest advances in basic science, while increasing their clinical orientation. You will also find self-assessment questions at the end of every chapter and current references from leaders in each subfield. The information presented in Visual Perception, Fifth Edition cannot be found in any other single volume. The book’s unique linkage of basic science and clinical application makes it of value to optometric and ophthalmologic students, faculty, and researchers. If you require a comprehensive text on visual science that imparts fundamental concepts in an engaging and interesting style, your search ends here.
This will help us customize your experience to showcase the most relevant content to your age group
Please select from below
Login
Not registered?
Sign up
Already registered?
Success – Your message will goes here
We'd love to hear from you!
Thank you for visiting our website. Would you like to provide feedback on how we could improve your experience?
This site does not use any third party cookies with one exception — it uses cookies from Google to deliver its services and to analyze traffic.Learn More.