Title

Login

Join

Book's by Steve Essinger

Covers

List

Computational Systems Biology

Chapter 14. Advances in Machine Learning for Processing and Comparison of Metagenomic Data

By: Jean-Luc Bouchot,William L. Trimble,Gregory Ditzler,Yemin Lan,Steve Essinger,Gail Rosen

Write a review Read reviews Take a Quiz Solve Book Puzzle

Computational Systems Biology

Chapter 14. Advances in Machine Learning for Processing and Comparison of Metagenomic Data

By: Jean-Luc Bouchot,William L. Trimble,Gregory Ditzler,Yemin Lan,Steve Essinger,Gail Rosen

Recent advances in next-generation sequencing have enabled high-throughput determination of biological sequences in microbial communities, also known as microbiomes. The large volume of data now presents the challenge of how to extract knowledge—recognize patterns, find similarities, and find relationships—from complex mixtures of nucleic acid sequences currently being examined. In this chapter we review basic concepts as well as state-of-the-art techniques to analyze hundreds of samples which each contain millions of DNA and RNA sequences. We describe the general character of sequence data and describe some of the processing steps that prepare raw sequence data for inference. We then describe the process of extracting features from the data, assigning taxonomic and gene labels to the sequences. Then we review methods for cross-sample comparisons: (1) using similarity measures and ordination techniques to visualize and measure differences between samples and (2) feature selection and classification to select the most relevant features for discriminating between samples. Finally, in conclusion, we outline some open research problems and challenges left for future research.

Average ratings

N/A

5

0%

4

0%

3

0%

2

0%

1

0%

Solve jigsaw puzzle

Age

Page Count

61

Publisher

Elsevier Inc. Chapters

Published Date

ISBN 10

0128070153

ISBN 13

9780128070154

Procurement Systems

A Cross-Industry Project Management Perspective

By: Derek Walker,Steve Rowlinson

Write a review Read reviews Take a Quiz Solve Book Puzzle

Procurement Systems

A Cross-Industry Project Management Perspective

By: Derek Walker,Steve Rowlinson

Innovative and novel, this book extends its coverage of the topic well beyond the conventional themes of project solicitation and proposal evaluation. Using extensive experience gathered over five years of teaching postgraduate courses, Walker and Rowlinson build on Procurement Systems: A Guide to Best Practice in Construction to present a comprehensive and coherent volume that is invaluable to the wider project management community. Cross-disciplinary in approach, coverage includes general historical issues and practical discussions of different types of projects and their procurement needs. It provides and discusses cutting-edge research and thought leadership on issues such as: stakeholder management ethics and corporate governance issues business strategy implications on procurement e-business innovation and organizational learning cultural dimensions human resource development. Helping readers to design project procurement implementation paths that deliver sustainable value, this indispensable volume is key reading for students, lecturers and professionals working in or studying project management.

Average ratings

N/A

5

0%

4

0%

3

0%

2

0%

1

0%

Solve jigsaw puzzle

Age

Page Count

537

Publisher

Routledge

Published Date

ISBN 10

1134117914

ISBN 13

9781134117918