Safely and effectively prescribe today's full spectrum of topical, intralesional, and systemic drugs for dermatologic disorders! Dr. Steven E. Wolverton and a team of leading international experts explain what drugs to use, when to use them...and what to watch out for. Handheld software - included with the book - provides full-text explanations as well as at-a-glance summaries of key pharmacologic information, instantly accessible wherever and whenever questions about skin pharmaceuticals arise. Provides at-a-glance access to key information including summaries of indications/contraindications, dosage guidelines, drug interactions, drug monitoring guidelines, adverse effects, and treatment protocols. Features a consistent organization throughout to expedite fast reference. Provides purchase information for major drugs, to help you and your patients. Includes a highly detailed, disease-specific index, helping you to evaluate drug options for each disease discussed. .Highlights key controversies and provides expert guidance in a Question and Answer feature. Presents new chapters on TNF Inhibitors, Signal II Cytokine Inhibitors, Pimicrolimus, IV Immunoglobulin, Drug-Induced Malignancies, Polymorphisms, and non-dermatologic drugs related to dermatologic problems. Features updates on new drug findings and new research, especially findings on predicting an individual response to drugs on the basis of ethnicity and gender.
From Stephen Coonts comes a novel of high octane excitement, featuring Tommy Carmellini in his most dangerous mission yet: The Assassin. In the finale of Coonts's last novel The Traitor, the ruthless and brilliant Al Qaeda leader who nearly succeeded in blowing up a meeting of the Group of 7 in Paris slipped the noose and escaped. But Abu Qasim has another trick up his sleeve: he has offered to pay a the Mafia a fortune to help him bring New York to its knees. The CIA learns that something is up and a worried president sends his best—Jake Grafton and his secret weapon, Tommy Carmellini. Tommy is soon in grave danger as he tries to piece the deadly puzzle together. Set amidst ticking bombs and flying bullets, the stakes have never been higher. Will Tommy put it all together in time t stop the disaster? Or will the terrorists set events in motion that will leave America reeling?
In Inwood's biography of this forgotten scientist, Robert Hooke and his world are vividly recreated with all their contradictions, successes, and failures. The Forgotten Genius is an absorbing and compelling study of this unduly overlooked man.
In this book, the authors give an up-to-date account of thermoluminescence (TL) and other thermally stimulated phenomena. Although most recent experimental results of TL in different materials are described in some detail, the main emphasis in the present book is on general processes, and the approach is more theoretical. Thus the details of the possible processes which can take place during the excitation of the sample, and during its heating, are carefully analysed. The methods for analysing TL glow curves are critically discussed, and recommendations as to their application are made. Also discussed is the expected behavior of these phenomena as functions of the experimental parameters, for example, dose of excitation. The consequences of the main applications of TL (for example, radiation dosimetry) are also discussed in detail as are the similarities and dissimilarities of other thermally stimulated phenomena, and the simultaneous measurements of the latter and TL.
This unique study of the Church of England between the 1660s and 1720s addresses the neglected research area of the Reformed school of thought and its powerful influence on the later eighteenth century church and evangelical revival. Hampton also explores consequences for understanding Anglican identity today.
Much expanded, fully revised, and with many more new illustrations, this remains the essential text for anyone who has to master the complexities of psychopharmacology.
James Boggs (1919-1993) and Grace Lee Boggs (1915-2015) were two largely unsung but critically important figures in the black freedom struggle. Born and raised in Alabama, James Boggs came to Detroit during the Great Migration, becoming an automobile worker and a union activist. Grace Lee was a Chinese American scholar who studied Hegel, worked with Caribbean political theorist C. L. R. James, and moved to Detroit to work toward a new American revolution. As husband and wife, the couple was influential in the early stages of what would become the Black Power movement, laying the intellectual foundation for racial and urban struggles during one of the most active social movement periods in recent U.S. history. Stephen Ward details both the personal and the political dimensions of the Boggses' lives, highlighting the vital contributions these two figures made to black activist thinking. At once a dual biography of two crucial figures and a vivid portrait of Detroit as a center of activism, Ward's book restores the Boggses, and the intellectual strain of black radicalism they shaped, to their rightful place in postwar American history.
German bombers are arriving daily, seeking to decimate England. But in a rural Hampshire village, things have remained fairly quiet—until an elderly loner, Will Blackwell, is brutally murdered. The method of his killing bears the hallmarks of the traditional vanquishing of a witch, and indeed, local legend claims that as a boy, Blackwell encountered a ghostly black dog sent from the devil, who struck a bargain for Blackwell’s soul.Not long after the murder, a young woman who is carrying the illegitimate child of a fighter pilot also is violently killed; then a local drunkard ends up in an abandoned mill with the back of his head bashed in. As the Germans continue their relentless attack, Detective Inspector Thomas Lamb rushes to solve the crimes. Do the killer’s motivations lie in the murky regions of the occult?
Death and Mr. Pickwick is a vast, richly imagined, Dickensian work about the rough-and-tumble world that produced an author who defined an age. Like Charles Dickens did in his immortal novels, Stephen Jarvis has spun a tale full of preposterous characters, shaggy-dog stories, improbable reversals, skulduggery, betrayal, and valor-all true, and all brilliantly brought to life in his unputdownable book. The Posthumous Papers of the Pickwick Club, featuring the fat and lovable Mr. Pickwick and his Cockney manservant, Sam Weller, began as a series of whimsical sketches, the brainchild of the brilliant, erratic, misanthropic illustrator named Robert Seymour, a denizen of the back alleys and grimy courtyards where early nineteenth-century London's printers and booksellers plied their cutthroat trade. When Seymour's publishers, after trying to match his magical etchings with a number of writers, settled on a young storyteller using the pen name Boz, The Pickwick Papers went on to become a worldwide phenomenon, outselling every other book besides the Bible and Shakespeare's plays. And Boz, as the young Charles Dickens signed his work, became, in the eyes of many, the most important writer of his time. The fate of Robert Seymour, Mr. Pickwick's creator, a very different story-one untold before now. Few novels deserve to be called magnificent. Death and Mr. Pickwick is one of them.
Religion appears to be about God, messiahs, churchgoing, and morality, but that is only the appearance. It is really about lust, rage, grief, love and the other core emotions. Why We Need Religion is about the way religion successfully manages human emotions, for the good of the individual and the group.
How did the concept of the secular state emerge and evolve in Australia and how has it impacted on its institutions? This is the most comprehensive study to date on the relationship between religion and the state in Australian history, focusing on the meaning of political secularity in a society that was from the beginning marked by a high degree of religious plurality. This book tracks the rise and fall of the established Church of England, the transition to plural establishments, the struggle for a public Christian-secular education system, and the eventual separation of church and state throughout the colonies. The study is unique in that it does not restrict its concern with religion to the churches but also examines how religious concepts and ideals infused apparently secular political and social thought and movements making the case that much Australian thought and institution building has had a sacral-secular quality. Social welfare reform, nationalism, and emerging conceptions of citizenship and civilization were heavily influenced by religious ideals, rendering problematic traditional linear narratives of secularisation as the decline of religion. Finally the book considers present day pluralist Australia and new understandings of state secularity in light of massive social changes over recent generations.
Tormented girls writhing in agony, stern judges meting out harsh verdicts, nineteen bodies swinging on Gallows Hill. The stark immediacy of what happened in 1692 has obscured the complex web of human passion, individual and organized, which had been growing for more than a generation before the witch trials. Salem Possessed explores the lives of the men and women who helped spin that web and who in the end found themselves entangled in it. From rich and varied sources—many previously neglected or unknown—Paul Boyer and Stephen Nissenbaum give us a picture of the events of 1692 more intricate and more fascinating than any other in the already massive literature on Salem. “Salem Possessed,” wrote Robin Briggs in The Times Literary Supplement, “reinterprets a world-famous episode so completely and convincingly that virtually all the previous treatments can be consigned to the historical lumber-room.” Not simply a dramatic and isolated event, the Salem outbreak has wider implications for our understanding of developments central to the American experience: the breakup of Puritanism, the pressures of land and population in New England towns, the problems besetting farmer and householder, the shifting role of the church, and the powerful impact of commercial capitalism.
This delightful book is the first comprehensive architectural guide to Bath, England's finest Georgian city. Full of new discoveries and lively descriptions, the book follows in the tradition of the celebrated Pevsner series. The great set-pieces of Bath - the famous Grand Pump Room, the Circus, the Royal Crescent - form a splendid sequence in a charming urban landscape developed by a long succession of gifted architects. The city's Roman roots are represented by its extraordinary baths, its medieval prosperity by the splendid Abbey. Exquisite crescents, terraces and villas grace the surrounding hills.
Prepare to think as you explore these wildly disparate literary short stories by author, composer, and producer Stephen Geez. Avoiding any single genre, this collection showcases Geez’s storytelling from southern gothic to contemporary drama to coming-of-age, humor, sci-fi, and fantasy—all finessed to say something about who we are and what we seek. Some of these have been passed around enough to need a shot of penicillin, others so virgin they have never known the seductive gaze of a reader’s eyes. So when life’s currents get to pulling too hard, don’t fight it, just open the book and discover nineteen new ways of going with the flow, because NOW more than ever Comes this Time to Float.
From Rodney King and “driving while black” to claims of targeting of undocumented Latino immigrants, relationships surrounding race, ethnicity, and the police have faced great challenge. Race, Ethnicity, and Policing includes both classic pieces and original essays that provide the reader with a comprehensive, even-handed sense of the theoretical underpinnings, methodological challenges, and existing research necessary to understand the problems associated with racial and ethnic profiling and police bias. This path-breaking volume affords a holistic approach to the topic, guiding readers through the complexity of these issues, making clear the ecological and political contexts that surround them, and laying the groundwork for future discussions. The seminal and forward-thinking twenty-two essays clearly illustrate that equitable treatment of citizens across racial and ethnic groups by police is one of the most critical components of a successful democracy, and that it is only when agents of social control are viewed as efficient, effective, and legitimate that citizens will comply with the laws that govern their society. The book includes an introduction by Robin S. Engel and contributions from leading scholars including Jeffrey A. Fagan, James J. Fyfe, Bernard E. Harcourt, Delores Jones-Brown, Ramiro Martínez, Jr., Karen F. Parker, Alex R. Piquero, Tom R. Tyler, Jerome H. Skolnick, Ronald Weitzer, and many others.
Drawn from the best-selling second edition of Essential Psychopharmacology, in this revised and updated new book Steve Stahl covers the many dimensions of psychosis (causes, pathophysiology, treatment and the role of dopamine). New material includes discussion of a promising new agent, aripiprazole, the first in a new class of dopamine stabilizers; the use of anticonvulsant agents; and the newest atypical antipsychotic ziprasidone. This book will be essential reading for all professionals treating psychosis, and students who need to know the mechanisms of drug actions. CME self-assessment tests are included.
Was there a advanced prehistoric civilization in ancient Egypt? Who were the people who built the great pyramids and carved the Great Sphinx? Did the pyramids serve as energy devices and not as tombs for kings? Independent Egyptologist Stephen S. Mehler has spent over 30 years researching the answers to these questions and believes the answers are "Yes!" An indigenous oral tradition still exists in Egypt, and Mehler has been able to uncover and study it with the help of a living master of this tradition, Abd1El Hakim Awyan. He has also been given permission to share these teachings—presented heretofore in fragments by other researchers—to the Western World, teachings that unfold a whole new understanding of ancient Egypt"--Publisher's description.
Annotation This first volume of the Savage Frontier series is a comprehensive account of the formative years of the legendary Texas Rangers. Stephen L. Moore provides fresh detail about each ranging unit formed during the Texas Revolution and narrates their involvement in the pivotal battle of San Jacinto and later battles at Parker's Fort, the Elm Creck Fight, Post Oak Springs Massacre, and the Stone Houses Fight. Of particular interest to the reader will be the various rosters of the companies, which are found throughout the book. The first edition was previously published by Republic of Texas Press in paperback only; it has now been reprinted in hardcover and paperback.
The structures of living tissues are continually changing due to growth and response to the tissue environment, including the mechanical environment. Tissue Mechanics is an in-depth look at the mechanics of tissues. Tissue Mechanics describes the nature of the composite components of a tissue, the cellular processes that produce these constituents, the assembly of the constituents into a hierarchical structure, and the behavior of the tissue’s composite structure in the adaptation to its mechanical environment. Organized as a textbook for the student needing to acquire the core competencies, Tissue Mechanics will meet the demands of advanced undergraduate or graduate coursework in Biomedical Engineering, as well as, Chemical, Civil, and Mechanical Engineering. Key features: Detailed Illustrations Example problems, including problems at the end of sections A separate solutions manual available for course instructors A website (http://tissue-mechanics.com/) that has been established to provide supplemental material for the book, including downloadable additional chapters on specific tissues, downloadable PowerPoint presentations of all the book's chapters, and additional exercises and examples for the existing chapters. About the Authors: Stephen C. Cowin is a City University of New York Distinguished Professor, Departments of Biomedical and Mechanical Engineering, City College of the City University of New York and also an Adjunct Professor of Orthopaedics, at the Mt. Sinai School of Medicine in New York, New York. In 1985 he received the Society of Tulane Engineers and Lee H. Johnson Award for Teaching Excellence and a recipient of the European Society of Biomechanics Research Award in 1994. In 1999 he received the H. R. Lissner medal of the ASME for contributions to biomedical engineering. In 2004 he was elected to the National Academy of Engineering (NAE) and he also received the Maurice A. Biot medal of the American Society of Civil Engineers (ASCE). Stephen B. Doty is a Senior Scientist at Hospital for Special Surgery, New York, New York and Adjunct Professor, School of Dental and Oral Surgery, Columbia University, New York, NY. He has over 100 publications in the field of anatomy, developmental biology, and the physiology of skeletal and connective tissues. His honors include several commendations for participation in the Russian/NASA spaceflights, the Spacelab Life Science NASA spaceflights, and numerous Shuttle missions that studied the influence of spaceflight on skeletal physiology. He presently is on the scientific advisory board of the National Space Biomedical Research Institute, Houston, Texas.
Now in its 7th edition, this popular, must-have text remains the only encyclopedic resource for veterinary internal medical problems. The internationally acclaimed "gold standard" offers unparalleled coverage of pathophysiology, diagnosis, and treatment of diseases affecting dogs and cats, as well as the latest information on the genome, clinical genomics, euthanasia, innocent heart murmurs, hyperbaric medicine, home prepared and raw diets, obesity, botulism, artificial pacing of the heart, cancer vaccines, and more. The 7th edition combines the convenience of a two-volume printed textbook with the enhanced functionality of an Expert Consult website that enables you to electronically search your entire book and study more efficiently. With instant access to the most reliable information available, you’ll always be at the forefront of veterinary care! Fully searchable online text provides fast, easy access to the most reliable information in the field. More than 150 clinical algorithms throughout the text aid in disease-identification and decision-making. Expanded online chapter content enhances your understanding through additional text, illustrations, tables, and boxes. Hyperlinked client information sheets streamline reference of specific conditions and enhance communication with clients. Extensive online reference list directs you to full-text PubMed abstracts for additional research. Thoroughly updated and expanded content, including 90 new chapters, addresses the latest developments across the full spectrum of small animal care. Companion Expert Consult website enhances your learning experience with the ability to search the entire electronic text instantly, make notes, and highlight content for easy review. Expert Consult also gives you instant access to: More than 150 procedural videos that guide you step-by-step through essential procedures. An interactive drug formulary that makes it easier to find and cross-reference key drug information. Audio files that help you identify heart abnormalities by their sound.
The American Association for the Advancement of Science's report on Vision and Change in Undergraduate Biology Education suggests that instructors "can no longer rely solely on trying to cover a syllabus packed with topics" but rather should "introduce fewer concepts but present them in greater depth." They further suggest that the principles embodied in a set of core concepts and competencies should be the basis for all undergraduate biology courses, including those designed for nonmajors. The theme of Tools for Critical Thinking in Biology will be the first and most fundamental of these competencies: the ability to apply the process of science. Biology courses and curricula must engage students in how scientific inquiry is conducted, including evaluating and interpreting scientific explanations of the natural world. The book uses diverse examples to illustrate how experiments work, how hypotheses can be tested by systematic and comparative observations when experiments aren't possible, how models are useful in science, and how sound decisions can be based on the weight of evidence even when uncertainty remains. These are fundamental issues in the process of science that are important for everyone to understand, whether they pursue careers in science or not. Where other introductory biology textbooks are organized by scientific concepts, Tools for Critical Thinking in Biology will instead show how methods can be used to test hypotheses in fields as different as ecology and medicine, using contemporary case studies. The book will provide students with a deeper understanding of the strengths and weaknesses of such methods for answering new questions, and will thereby change the way they think about the fundamentals of biology.
The natural history museum is a place where the line between "high" and "low" culture effectively vanishes--where our awe of nature, our taste for the bizarre, and our thirst for knowledge all blend happily together. But as Stephen Asma shows in Stuffed Animals and Pickled Heads, there is more going on in these great institutions than just smart fun. Asma takes us on a wide-ranging tour of natural history museums in New York and Chicago, London and Paris, interviewing curators, scientists, and exhibit designers, and providing a wealth of fascinating observations. We learn how the first museums were little more than high-toned side shows, with such garish exhibits as the pickled head of Peter the Great's lover. In contrast, today's museums are hot-beds of serious science, funding major research in such fields as anthropology and archaeology. "Rich in detail, lucid explanation, telling anecdotes, and fascinating characters.... Asma has rendered a fascinating and credible account of how natural history museums are conceived and presented. It's the kind of book that will not only engage a wide and diverse readership, but it should, best of all, send them flocking to see how we look at nature and ourselves in those fabulous legacies of the curiosity cabinet."--The Boston Herald.
The poetry of Horace was central to Victorian male elite education and the ancient poet himself, suitably refashioned, became a model for the English gentleman. Horace and the Victorians examines the English reception of Horace in Victorian culture, a period which saw the foundations of the discipline of modern classical scholarship in England and of many associated and lasting social values. It shows that the scholarly study, translation and literary imitation of Horace in this period were crucial elements in reinforcing the social prestige of Classics as a discipline and its function as an indicator of 'gentlemanly' status through its domination of the elite educational system and its prominence in literary production. The book ends with an epilogue suggesting that the framework of study and reception of a classical author such as Horace, so firmly established in the Victorian era, has been modernised and 'democratised' in recent years, matching the movement of Classics from a discipline which reinforces traditional and conservative social values to one which can be seen as both marginal and liberal.
No single human invention has transformed war more than the airplane—not even the atomic bomb. Even before the Wright Brothers’ first flight, predictions abounded of the devastating and terrible consequences this new invention would have as an engine of war. Soaring over the battlefield, the airplane became an unstoppable force that left no spot on earth safe from attack. Drawing on combat memoirs, letters, diaries, archival records, museum collections, and eyewitness accounts by the men who fought—and the men who developed the breakthrough inventions and concepts—acclaimed author Stephen Budiansky weaves a vivid and dramatic account of the airplane’s revolutionary transformation of modern warfare. On the web: http://www.budiansky.com/
The South's system of Jim Crow racial oppression is usually understood in terms of legal segregation that mandated the separation of white and black Americans. Yet, as Stephen A. Berrey shows, it was also a high-stakes drama that played out in the routines of everyday life, where blacks and whites regularly interacted on sidewalks and buses and in businesses and homes. Every day, individuals made, unmade, and remade Jim Crow in how they played their racial roles--how they moved, talked, even gestured. The highly visible but often subtle nature of these interactions constituted the Jim Crow routine. In this study of Mississippi race relations in the final decades of the Jim Crow era, Berrey argues that daily interactions between blacks and whites are central to understanding segregation and the racial system that followed it. Berrey shows how civil rights activism, African Americans' refusal to follow the Jim Crow script, and national perceptions of southern race relations led Mississippi segregationists to change tactics. No longer able to rely on the earlier routines, whites turned instead to less visible but equally insidious practices of violence, surveillance, and policing, rooted in a racially coded language of law and order. Reflecting broader national transformations, these practices laid the groundwork for a new era marked by black criminalization, mass incarceration, and a growing police presence in everyday life.
Apply the latest scientific and clinical advances with Wall & Melzack's Textbook of Pain, 6th Edition. Drs. Stephen McMahon, Martin Koltzenburg, Irene Tracey, and Dennis C. Turk, along with more than 125 other leading authorities, present all of the latest knowledge about the genetics, neurophysiology, psychology, and assessment of every type of pain syndrome. They also provide practical guidance on the full range of today's pharmacologic, interventional, electrostimulative, physiotherapeutic, and psychological management options. Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located. Benefit from the international, multidisciplinary knowledge and experience of a "who's who" of international authorities in pain medicine, neurology, neurosurgery, neuroscience, psychiatry, psychology, physical medicine and rehabilitation, palliative medicine, and other relevant fields. Translate scientific findings into clinical practice with updates on the genetics of pain, new pharmacologic and treatment information, and much more. Easily visualize important scientific concepts with a high-quality illustration program, now in full color throughout. Choose the safest and most effective management methods with expanded coverage of anesthetic techniques. Stay abreast of the latest global developments regarding opioid induced hyperalgesia, addiction and substance abuse, neuromodulation and pain management, identification of specific targets for molecular pain, and other hot topics.
Celebrating the centenary of women legislators’ membership in the Arkansas General Assembly, Stateswomen shines a light on the women who have served as some of the state’s central decision makers. Drawing on documentary research and oral histories, Lindsley Armstrong Smith and Stephen A. Smith present lively, concise biographies for the nearly 150 women legislators who have served in the general assembly to date, chronicling their personal histories, volunteer work and social activism, and legislative victories. In a probing introduction, the authors examine the neglected role of women in Arkansas political history alongside the “long history of resistance to full citizenship rights for women in Arkansas”—demonstrating that political representation is essential for improving opportunities in the wider society. The first comprehensive study dedicated to these trailblazing Arkansas legislators, Stateswomen will surely inspire history buffs, community-minded citizens, and political hopefuls alike.
Based on a decade of archaeological investigation and historical research, this book tells the story of the Copes of Hanwell Castle in north Oxfordshire and the creation of a garden with links to the development of scientific thinking in Oxford in the late seventeenth century. New research using Robert Plot’s Natural History of Oxfordshire as a starting point has uncovered details of a remarkable family and their rise and tragic downfall, their social circle, that included some great names in the development of early scientific thinking, and their garden that in effect became a place dedicated to the wonders of technology. The complex tale weaves together the activities of a royalist agent, Richard Allestree, a prodigious musician, Thomas Baltzar, John Claridge, a Hanwell Shepherd with a penchant for weather forecasting, and Sir Anthony Cope who in an atmosphere of secrecy and distrust began to gather together a community that eventually was named by Plot as The New Atlantis, a reference to a book published earlier in the century by Sir Francis Bacon in which he suggests a model for a Utopian science-focused society. The book also chronicles the program of archaeological excavation that has uncovered several unusual garden features and, most significantly of all, describes in detail the unique collection of seventeenth-century terracotta garden urns, an assemblage that is unparalleled in post-medieval archaeology. This collection was destroyed in a single episode of vandalism around 1675 and has been preserved in deeply buried deposits of mud and silt. Their analysis and reconstruction is opening new insights into the decorative schemes of seventeenth-century gardens. There is coverage of other gardens of the period and their surviving features as well as an examination of early science and how gardens impacted on its development in many ways.
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