This collection of challenging and well-designed test problems arising in literature studies also contains a wide spectrum of applications, including pooling/blending operations, heat exchanger network synthesis, homogeneous azeotropic separation, and dynamic optimization and optimal control problems.
Polysaccharides and related high molecular weight glycans are hugely diverse with wide application in Biotechnology and great opportunities for further exploitation. An Introduction to Polysaccharide Biotechnology – a second edition of the popular original text by Tombs and Harding – introduces students, researchers, clinicians and industrialists to the properties of some of the key materials involved, how these are applied, some of the economic factors concerning their production and how they are characterized for regulatory purposes.
Rutter’s Child and Adolescent Psychiatry has become an established and accepted textbook of child psychiatry. Now completely revised and updated, the fifth edition provides a coherent appraisal of the current state of the field to help trainee and practising clinicians in their daily work. It is distinctive in being both interdisciplinary and international, in its integration of science and clinical practice, and in its practical discussion of how researchers and practitioners need to think about conflicting or uncertain findings. This new edition now offers an entirely new section on conceptual approaches, and several new chapters, including: neurochemistry and basic pharmacology brain imaging health economics psychopathology in refugees and asylum seekers bipolar disorder attachment disorders statistical methods for clinicians This leading textbook provides an accurate and comprehensive account of current knowledge, through the integration of empirical findings with clinical experience and practice, and is essential reading for professionals working in the field of child and adolescent mental health, and clinicians working in general practice and community pediatric settings.
Maidstone in the Great War tells the remarkable story of this Kent county town's immense contribution to the Great War effort from the outbreak of war in 1914, to the long-awaited Allied victory in 1918. Maidstone has a long and illustrious military history it even had its own Civil War battle, dating back to 1648 and with the onset of the First World War, its civilians, like thousands of communities up and down the country, sent their men off to fight for their king and country. The town paid a hefty price as it lost nearly 900 of its young men. The harbinger of death catered for all strands of society, from the richest to the poorest, from those who toiled in the fields, to the loftiest of society. The book looks at the war year by year and how it directly and indirectly affected Maidstone. As more and more of its young men were killed and wounded, everyday life, or what passed for everyday life, continued the best that it could. The town's incredible support for the war on the Home Front was apparent from the very beginning. When the Mayor of Maidstone appealed to the town's people to support Lord Kitchener's request for blankets for his New Army, they responded in droves. Convalescing soldiers were tended to as passionately as Belgium refugees were looked after by the town's people; they freely and happily did this while coping with the unsettling reality that one or more of their loved ones may never return from the war. This is a superb account of the people of Maidstone's outstanding determination to see the war through.
To what extent should parents be allowed to use reproductive technologies to determine the characteristics of their future children? And is there something morally wrong with parents who wish to do this? Choosing Tomorrow's Children provides answers to these (and related) questions. In particular, the book looks at issues raised by selective reproduction, the practice of choosing between different possible future persons by selecting or deselecting (for example) embryos, eggs, and sperm. Wilkinson offers answers to questions including the following. Do children have a 'right to an open future' and, if they do, what moral constraints does this place upon selective reproduction? Should parents be allowed to choose their future children's sex? Should we 'screen out' as much disease and disability as possible before birth, or would that be an objectionable form of eugenics? Is it acceptable to create or select a future person in order to provide lifesaving tissue for an existing relative? Is there a moral difference between selecting to avoid disease and selecting to produce an 'enhanced' child? Should we allow deaf parents to use reproductive technologies to ensure that they have a deaf child?
Managing the Drug Discovery Process: How to Make It More Efficient and Cost-Effective thoroughly examines the current state of pharmaceutical research and development by providing chemistry-based perspectives on biomedical research, drug hunting and innovation. The book also considers the interplay of stakeholders, consumers, and the drug firm with attendant factors, including those that are technical, legal, economic, demographic, political, social, ecological, and infrastructural. Since drug research can be a high-risk, high-payoff industry, it is important to researchers to effectively and strategically manage the drug discovery process. This book takes a closer look at increasing pre-approval costs for new drugs and examines not only why these increases occur, but also how they can be overcome to ensure a robust pharmacoeconomic future. Written in an engaging manner and including memorable insights, this book is aimed at redirecting the drug discovery process to make it more efficient and cost-effective in order to achieve the goal of saving countless more lives through science. A valuable and compelling resource, this is a must-read for all students and researchers in academia and the pharmaceutical industry. Considers drug discovery in multiple R&D venues, including big pharma, large biotech, start-up ventures, academia, and nonprofit research institutes Analyzes the organization of pharmaceutical R&D, taking into account human resources considerations like recruitment and configuration, management of discovery and development processes, and the coordination of internal research within, and beyond, the organization, including outsourced work Presents a consistent, well-connected, and logical dialogue that readers will find both comprehensive and approachable
How elections are reported has important implications for the health of democracy and informed citizenship. But, how informative are the news media during campaigns? What kind of logic do they follow? How well do they serve citizens?e Based on original research as well as the most comprehensive assessment of election studies to date, Cushion and Thomas examine how campaigns are reported in many advanced Western democracies. In doing so, they engage with debates about the mediatization of politics, media systems, information environments, media ownership, regulation, political news, horserace journalism, objectivity, impartiality, agenda-setting, and the relationship between media and democracy more generally. Focusing on the most recent US and UK election campaigns, they consider how the logic of election coverage could be rethought in ways that better serve the democratic needs of citizens. Above all, they argue that election reporting should be driven by a public logic, where the agenda of voters takes centre stage in the campaign and the policies of respective political parties receive more airtime and independent scrutiny. The book is essential reading for scholars and students in political communication and journalism studies, political science, media and communication studies.
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