New epidemics such as AIDS and 'mad cow' disease have dramatized the need to explore the factors underlying rapid viral evolution and emerging viruses. Now available in paperback, this comprehensive book is the first to describe this multifaceted new field. The book places viral evolution and emergence in a historical context, describes the interaction of viruses with hosts, and details the advances in molecular biology and epidemiology that have provided the tools necessary to track developing viral epidemics and to detect new viruses far more successfully than could be done in the recent past. Case histories and practical suggestions for the prevention of future epidemics are given. From reviews of the hardback: "excellent examples of emerging virus diseases ... an excellent training resource, and should be required reading for all infectious disease and public health professionals.
A succinct review of hundreds of studies on the regulation of protein mass and protein turnover in the human body. The book summarizes the biochemistry of protein synthesis and breakdown, and explains the methods that are used to examine protein metabolism in humans, together with their limitations. Chapters review the effects of nutrition, hormones, metabolic substrates, and physical activity, while various topics of clinical interest include cancer, diabetes, tissue injury, pregnancy, renal disease, muscular dystrophies, and other conditions. Normal values are presented for turnover of proteins in the whole body and individual organs, and for turnover of many individual proteins. This is thus a valuable resource for physiologists, nutritionists, and clinicians interested in the regulation of body protein stores in health and disease. For scientists primarily interested in the basic aspects of protein metabolism, it shows how the basic knowledge is being applied to the study of humans.
In this “engrossing, well-documented, and highly readable” (San Francisco Chronicle) New York Times bestseller, three veteran reporters draw on top sources inside and outside the U.S. government to reveal Washington's secret strategies for combating germ warfare and the deadly threat of biological and chemical weapons. Today Americans have begun to grapple with two difficult truths: that there is no terrorist threat more horrifying—and less understood—than germ warfare, and that it would take very little to mount a devastating attack on American soil. Featuring an inside look at how germ warfare has been waged throughout history and what form its future might take (and in whose hands), Germs reads like a gripping detective story told by fascinating key figures: American and Soviet medical specialists who once made germ weapons but now fight their spread, FBI agents who track Islamic radicals, the Iraqis who built Saddam Hussein's secret arsenal, spies who travel the world collecting lethal microbes, and scientists who see ominous developments on the horizon. With clear scientific explanations and harrowing insights, Germs is a vivid, masterfully written—and timely—work of investigative journalism.
The overwhelming victory of Henry V's English army at Agincourt in October 1415 has passed into myth as one of the defining events of the Hundred Years War against France, as a feat of arms outshining the previous famous English victories at Crcy and Poitiers, and as a milestone in English medieval history. This epic story of how an exhausted, outnumbered army, commanded by an inspirational leader, crushed a huge French force on French soil has given rise to legends and misconceptions that make it difficult for us to reach a clear understanding of what really happened on the battlefield 600 years ago. But that is what Stephen Cooper attempts in this thoroughgoing, perceptive and fascinating reconstruction and reassessment of the battle and its history. In graphic detail he describes the battle itself and the military expedition that led to it. He examines the causes of the conflict and the controversies associated with it, and traces how the story of the battle has been told over the centuries, by eyewitnesses and chroniclers and by the historians of the present day.As featured in the Yorkshire Post, The Star (Sheffield) and Rotherham Advertiser.
In words and photographs, the story of visionary architect Addison Mizner * Introduced the Mediterranean Revival and Spanish Colonial Revival styles to southern Florida * Designed and developed the resort town of Boca Raton * Designed the exquisite Everglades Club in Palm Beach Addison Mizner transformed Palm Beach and South Florida with his visionary architecture. He designed, among many others, the landmark Everglades Club in Palm Beach and the Boca Raton Resort and Club in Boca Raton. In this detailed biography, Stephen Perkins and James Caughman examine Mizner's life and origins, and explore how the events of his life influenced his marvelous architectural legacy.
The history of anthropology at Harvard is told through vignettes about the people, famous and obscure, who shaped the discipline at Harvard College and the Peabody Museum. The role of amateurs and private funders in the early growth of the field is highlighted, as is the participation of women and of students and scholars of diverse ethnicities.
This is a complete history of the England rugby union team - told by the players themselves. Based on a combination of painstaking research into the early years of the England team through exclusive interviews with a vast array of Test match stars from before the Second World War to the present day, world-renowned rugby writers Stephen Jones and Nick Cain delve to the very heart of the English international rugby union experience, painting a unique and utterly compelling picture of the game in the only words that can truly do so: the players' own. This is the definitive story of English Test match rugby - a story etched in blood, sweat and tears; a story of great joy and heart-breaking sorrow; a story of sacrifice, agony, endeavour and triumph. Behind the Rose lifts the lid on what it is to play for England - the trials and tribulations behind the scenes, the glory, the drama and the honour on the field, and the heart-warming tales of friendship and humour off it. Absorbing and illuminating, this is a must-have for all supporters who have ever dreamed of walking the hallowed corridors of Twickenham as a Test match player, preparing themselves for battle in the changing rooms and then marching out to that field of dreams with the deafening roar of the crowd in their ears and the red rose emblazoned on their chest.
Of all the costly campaigns fought across the Western Front during the First World War, none strikes a more chilling chord than Passchendaele. Even now, more than ninety years on, the very mention of the name is enough to conjure up apocalyptic images of desolation and misery on a quite bewildering scale – humanity drowning in a sea of mud. Passchendaele has come to serve as a symbol of the folly and futility of war, chiefly remembered for its carnage and profligate waste of human lives. It also stands as testament to the endurance and extraordinary courage displayed by men of all ranks and nationalities. During the 3 1⁄2 month long struggle, which claimed the lives of more than 60,000 British and Commonwealth servicemen, 61 men were adjudged to have performed deeds worthy of the Empire's highest award for valour – the Victoria Cross. Men from Australia, Canada, New Zealand and South Africa were among their number, alongside men from England, Ireland, Scotland and Wales. They came from all walks of life, counting humble privates and, for the first time, a general among their ranks. This is a lasting memorial to a body of men who deserve to be numbered among the bravest of the brave.
The history of Tokyo is as eventful as it is long. A concise yet detailed overview of this fascinating, centuries-old city, Tokyo: A Biography is a perfect companion volume for history buffs or Tokyo-bound travelers looking to learn more about their destination. In a whirlwind journey through Tokyo's past from its earliest beginnings up to the present day, this Japanese history book demonstrates how the city's response to everything from natural disasters to regime change has been to reinvent itself time and again. A calamitous fire results in a massive expansion of the city's territory. A debate over the Samurai code creates far-reaching social change. A malleable boy becomes the figurehead for powerful forces which change an ancient feudal society into a modern industrialized power within a generation. Utter destruction wipes the slate clean again so Tokyoites may start all over. And so it goes. Tokyo's story is riveting, and by the end of Tokyo: A Biography, readers see a city almost unrivaled in its uniqueness, a place that--despite its often tragic history--still shimmers as it prepares to face the future.
The text provides basic and comprehensive coverage of all aspects of surgery for the vitreous and the retina. The key to this volume is that it is technique based, thus giving the surgeon clear instructions on how to perform vitreoretinal surgery. Not only is this book authoritative, it is practical. Each chapter is fully illustrated with the steps performed in the actual surgical operation.
This book explores how social groups in the urban fringe of Abuja, Nigeria, engaged with a series of development projects spanning 15 years (2003 to 2018) which focused on the enhancement of food security for farming households. The groups were at the heart of these development projects and the book presents the many insights that were gained by farmers and project agents working within these partnerships and provides advice for those seeking to do the same. The book also explores how the social groups attempted to lever benefits from being near to the fastest growing city in Africa and a centre of economic and political power. While much has been written about social groups and their embeddedness within wider social networks in Africa and in other parts of the world, the exploration of the role of social groups within development projects is an area that remains relatively unchartered and this book seeks to fill that important gap in knowledge. It provides an important contribution for all those researching and working with social groups in the developing world.
We all view the ubiquitous term ‘sustainability’ as a worthwhile goal. But how can we apply the principles of sustainability in the real world, at the sharp end of communities in developing nations where income insecurity is the troubled norm? This volume provides some practical answers, explaining the precepts of the ‘sustainable livelihood approach’ (SLA) through the case study of a microfinance scheme in Africa. The case study, centered around the work of the Catholic Church’s Diocesan Development Services organization, involved an SLA implemented over two years designed in part to help enhance its existing microfinance operation through closer links between local communities and international donors. The book’s central conclusion is that we must move beyond the concept of sustainable livelihood itself, with its in-built polarities between developed and developing nations, and embrace a more global notion of ‘sustainable lifestyle’; a more nuanced and inclusive approach that encompasses not just how we make a sustainable living, but how we can live sustainable lives.
Praise for the first edition: 'This book should be of interest to anyone interested in sustainable development, and especially sustainability indicators. Bell and Morse easily succeed in exposing the fundamental paradoxes of these concepts and, more importantly, they offer us a way forward. Readers ... will find their practical recommendations for those attempting to do sustainability analysis in the field most welcome, which is also the book's greatest strength.' Local Environment: The International Journal of Justice and Sustainability 'This book makes a valuable contribution to the theory and practice of using indicators for sustainability. It introduces systems ideas and a range of tools and techniques that have the potential to broaden and deepen our understanding of a whole range of complex situations. Well worth a closer look.' Christine Blackmore, Open University 'This is a book that explores new ways of thinking about how to measure sustainability... It offers stimulating food for thought for environmental educators and researchers.' Environmental Education Research 'This book tells me, as an SI 'practitioner', where I have been and why, and more importantly how I should be thinking in order to effectively present to and empower the local community in the years ahead.' David Ellis, Principal Pollution Monitoring Officer, Norwich City Council 'A practical guide to the development of sustainability indicators which offers a systemic and participative way to use them at local scale. Our preliminary results are highly positive and the approach is applicable in many contexts.' Elisabeth Coudert, Programme Officer Prospective and Regional Development, Blue Plan The groundbreaking first edition of Sustainability Indicators reviewed the development and value of sustainability indicators and discussed the advantage of taking a holistic and qualitative approach rather than focusing on strictly quantitative measures. In the new edition the authors bring the literature up to date and show that the basic requirement for a systemic approach is now well grounded in the evidence. They examine the origins and development of Systemic Sustainability Analysis (SSA) as a theoretical approach to sustainability which has been developed in practice in a number of countries on an array of projects since the first edition. They look at how SSA has evolved into the practical approaches of Systemic Prospective Sustainability Analysis (SPSA) and IMAGINE, and, in particular, how a wide range of participatory methodologies have been adopted over the years. They also provide an assessment of the strengths and weaknesses of projects that undertake work in the general field of sustainable development.
Chapter 3: Systemic Sustainability Analysis and Prospective; Introduction; The importance of the subjective; Background to CAMP Malta; Technical specification for SSA; Familiarizing the Maltese SSA team; What are SSA and SPSA and how are they different?; SPSA and Blue Plan approaches; Chapter 4: Doing SPSA: Some Reflective Experience; Introduction; Stage 1: Find out how things are: reflection; Stage 2: Understand the context for sustainability indicators: reflection/connection; Stage 3: Gather the stakeholders in the sustainability indicator process: reflection/connection.
Corporate Social Responsibility (CSR) has become an important concept in the last few decades. Although it originated in the developed countries of the West, the concept has been embraced and adapted by corporations and policy-making agencies in many developing countries. Not surprisingly, given the importance of growth and development as policy objectives in these countries, CSR has had a significant impact on sustainable development. Sustainable Development and Corporate Social Responsibility explores the evolution of CSR across the developed and developing world, with a particular focus on China and sustainable development. Through an extensive review of the literature and relevant case studies, the book examines whether CSR can make a contribution to sustainable development, how the patterns of CSR in developed Western economies compare to that in the rapidly growing economy of China, what trade-offs take place between CSR and economic growth as well as the future of CSR and its possible impact on the global sustainable development agenda. This book is a valuable resource for academics and upper-level undergraduate and postgraduate students in the fields of human/social geography, economics, business studies, sustainable development, development studies and environmental studies.
This title was first published in 2000: Sustainable development has grown to compass cultural, socio-economic, political and environmental issues, and the use of Sustainability indicators (SIs) is seen by many as central to its implementation. After all, how can one ’do’ sustainable development unless one knows when it has been attained? The adoption of SIs in such a context is logical, but does present a number of practical difficulties. So far much of the published material consists of theoretical SI frameworks, with little practical experience on their use in development scenarios. In contrast, this volume is based on the results of a six year project designed to develop and evaluate the use of SLs in a Nigerian village. For the first time this takes into consideration the views and perspectives of the local population, and in doing so addresses key issues that are vital for anyone attempting to put sustainable development into practice.
This invaluable book contains the collected papers of Stephen Smale. These are divided into eight groups: topology; calculus of variations; dynamics; mechanics; economics; biology, electric circuits and mathematical programming; theory of computation; miscellaneous. In addition, each group contains one or two articles by world leaders on its subject which comment on the influence of Smale's work, and another article by Smale with his own retrospective views.
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