Short, factual description of the book (summary of what it includes, without subjective or promotional language.) This book, for upper undergraduate and graduate students and professionals in the field, is used to provide an overview of how the environment impacts exercise"--
Finally, the authoritative resource that serious cyclists have been waiting for has arrived. The perfect blend of science and application, Cycling Science takes you inside the sport, into the training room and research lab, and onto the course. A remarkable achievement, Cycling Science features the following: • Contributions from 43 top cycling scientists and coaches from around the world • The latest thinking on the rider-machine interface, including topics such as bike fit, aerodynamics, biomechanics, and pedaling technique • Information about environmental stressors, including heat, altitude, and air pollution • A look at health issues such as on-bike and off-bike nutrition, common injuries, fatigue, overtraining, and recovery • Help in planning training programs, including using a power meter, managing cycling data, off-the-bike training, cycling specific stretching, and mental training • The latest coaching and racing techniques, including pacing theories, and strategies for road, track, MTB, BMX, and ultra-distance events In this book, editors and cycling scientists Stephen Cheung, PhD, and Mikel Zabala, PhD, have assembled the latest information for serious cyclists.
Since 1975, Dr. Kenneth Swaiman's classic text has been the reference of choice for authoritative guidance in pediatric neurology, and the 6th Edition continues this tradition of excellence with thorough revisions that bring you fully up to date with all that's new in the field. Five new sections, 62 new chapters, 4 new editors, and a reconfigured format make this a comprehensive and clearly-written resource for the experienced clinician as well as the physician-in-training. - Nearly 3,000 line drawings, photographs, tables, and boxes highlight the text, clarify key concepts, and make it easy to find information quickly.
Cantonese: A Comprehensive Grammar is a complete reference guide to Cantonese as spoken by native speakers in Hong Kong. It presents a fresh and accessible description of the language, concentrating on the real patterns of use in current Cantonese. This makes it the ideal reference source for all learners and users of Cantonese, irrespective of level, in schools, colleges, universities and adult classes of all types. Moreover, it will provide a lasting and reliable resource for all fluent speakers of the language. The book is organized to promote a thorough understanding of Cantonese grammar. Arranged by both syntactic categories and language functions, the Grammar provides an in-depth treatment of structures and pays special attention to idiom and speech registers. Explanations are full, clear and free of jargon. An extensive index, numbered paragraphs and generous use of headings and cross-references provide readers with easy access to the information they require. Features include: Comprehensive pronunciation section Full use of examples from films, advertising and authentic conversations Cantonese-English parallels highlighted throughout the book All examples given in characters as well as pinyin
Increase speed, power, endurance, and efficiency with Cutting-Edge Cycling. You’ll learn how to apply the latest in cycling research, science, and technology to train smarter, ride longer, and race faster. Renowned cycling coach Hunter Allen and leading scientist Stephen Cheung share the most recent biomechanical, physiological, and technical advances and research, why they matter, and how you can incorporate them for maximal training and optimal performance. From the latest information on periodization, lactate threshold, and recovery to bike positioning, pedaling technique, and cadence, Cutting-Edge Cycling covers every aspect of conditioning, preparation, and competition in this physically demanding sport. Additional coverage includes interviews that cover a broad range of topics: interpreting lab results, fatigue, monitoring training, high-intensity training, prevention of and recovery from overtraining, pacing, bike fit, power meter quadrant analysis, hydration, and cooling strategies. If you’re serious about gaining the edge on the competition, Cutting-Edge Cycling is one guide you shouldn’t be without.
The application of knowledge of drug disposition, and skills in pharmacokinetics, are crucial to the development of new drugs and to a better understanding of how to achieve maximum benefit from existing ones. The book takes the reader from basic concepts to a point where those who wish to will be able to perform pharmacokinetic calculations and be ready to read more advanced texts and research papers. The book will be of benefit to students of medicine, pharmacy, pharmacology, biomedical sciences and veterinary science, including those who have elected to study the topic in more detail, such as via electives and special study modules. It will be of benefit to those involved in drug discovery and development, pharmaceutical and medicinal chemists, as well as budding toxicologists and forensic scientists who require the appropriate knowledge to interpret their findings and as an introductory text for clinical pharmacologists. Early chapters describe the basic principles of the topic while the later ones illustrate the application of those principles to modern approaches to drug development and clinical use. Full colour illustrations facilitate the learning experience and supporting material for course leaders and students can be found on the Companion Web Site "Another book on PK? Yes and there should be and it should be DD & PK. It is good, unique, and does fill a currently unmet need for those working in the xenobiotic arena. DD & PK is just like the perfect mystery novel—the one “you just can’t put down.” However, unlike a mystery novel which requires only one reading to find the answer, the reader of DD & PK will learn more than an answer to a single question. The reader will find many solutions to a wide variety of mysterious problems associated with the time course and actions of xenobiotics." —International Journal of Toxicology, John A. Budny, PhD, President, PharmaCal, Ltd, 2018 "This book has many innovations that make a welcome addition to the bookshelves of a wide range of pharmaceutical scientists. The effective use of figures and tables to summarize and clarify a wide range of issues is to be commended, as are the learning objectives at the start of the chapter coupled with the summary at the end providing a succinct way in understanding the objectives of the chapter and together with links to a website provides accessibility for all from the neophyte pharmacokineticist to the consultant physician. A book all in the Pharma industry should be aware of." —Int. J. of Pharmacokinetics, Howard M. Hill, ResolvPharma, 2018 "Overall, Introduction to Drug Disposition and Pharmacokinetics offers its readership an in-depth view of classic pharmacokinetic concepts. This book would be an excellent choice for a pharmacokinetics elective or as an adjunctive text for an introductory course. This book reviews a wide array of clinically relevant topics and encourages the reader to apply the knowledge gained to all medi-cations. A robust and varied amount of online material is provided to enhance understanding and encourage discussion. It is likely that all readers, novice or experienced pharmacists, would find value in this textbook." — Currents in Pharmacy Teaching and Learning, Milena McLaughlin, Midwestern University Chicago College of Pharmacy, 2018 "In summary, this is an excellent textbook for students new to the field of pharmaceutics and medical, pharmacy, and veterinary students, particularly those who envision a career in drug development research in either academia or industry." —Veterinary Pathology Review, John K. Amory, University of Washington, 2018
Despite the fact that elderly persons have a 33-35% chance of falling and becoming injured, most are ill-prepared. According to the World Health Organization, falls cause over 50% of accidental injuries and 39% of fatal injuries in the elderly. They are the fifth leading cause of death in the general population. Falls can be either non-mechanical, related to underlying illness or debilitation, or they can be mechanical, related to accidental trips and slips and caused by environmental factors such as poor lighting, surprise steps, lack of grab bars, and slippery bathroom floors. Non-mechanical falls can be related to cognitive disorders, such as stroke or dementia, or to frailty. They can also be related to over-medicating with sedatives, diabetic medications, or blood pressure therapy. Falls can be the consequence of aging or chronic diseases such as heart disease, diabetes, kidney disease, or cancer. Patients with any of these disorders may have poor muscle tone, walking disorders, or a loss of equilibrium. Mechanical falls may be completely avoided by fall-proofing the home environment. This book outlines several practical tips for eliminating potential home hazards and reviews each of the major causes of falls to help the patient and his or her caregiver, as well as the health provider, prevent falling by adapting one's lifestyle. The book also covers exercise programs and community programs that can be established and used to minimize the risk of falling in the elderly. Given that falls are common and that the majority of persons who fall are ill-prepared, this book will raise awareness of fall-prevention measures that can help reduce falls and fall-related injuries.
Drug Disposition and Pharmacokinetics The most up-to-date edition of a leading reference in drug disposition and pharmacokinetics In this new, fully-revised edition of Drug Disposition and Pharmacokinetics: Principles and Applications for Medicine, Toxicology and Biotechnology the authors deliver an authoritative and comprehensive discussion of the fate of drug molecules in the body, as well as its implications for pharmacological and clinical effects. The text offers a unique and balanced approach that combines discussion of the specific physical and biological factors affecting the absorption, distribution, metabolism, and excretion of drugs, with mathematical assessments of plasma and body fluid concentrations. The book assumes little prior knowledge and is an ideal reference for practicing professionals in industry as well as researchers and academics. This latest edition provides readers with a new introductory chapter, as well as new chapters covering monoclonal antibodies, the role of stereochemistry in drug disposition and pharmacokinetics, DMPK in non-human species, and the recent use of AI in drug development. Readers will also find: Thorough introductions to drug disposition, pharmacokinetics, and pharmacokinetic modeling In-depth treatments of the kinetics of drug elimination and the relationship between concentration and effect, including PK–PD modeling Comprehensive discussions of predictive pharmacokinetics and the disposition of biological molecules, including peptides and monoclonal antibodies Detailed examinations of the effects of sex, pregnancy, age, and disease, as well as drug monitoring in therapeutics and the use of AI in drug development and treatment Perfect for professionals and researchers working with the scientific aspects of drug disposition in human and veterinary medicine, toxicology, and pharmacology. Drug Disposition and Pharmacokinetics will earn a place in the libraries of students of senior-level courses in pharmacy.
This best-selling resource has a worldwide reputation as the leader in its field. Focusing on human immunology and biology, while also reporting on scientific experimentation and advancement, it provides comprehensive coverage of state-of-the-art basic science as well as authoritative guidance on the practical aspects of day-to-day diagnosis and management. This new edition includes 700 full-color illustrations and a new, more accessible format to make finding information a snap for the busy practitioner. Includes a glossary of allergy and immunology for quick and easy reference. Contains keypoints and clinical pearls highlighted to find important information quickly. links to useful online resources both for you and for your patients. Offers contributions from hundreds of international authorities for world-class expertise in overcoming any clinical challenge. Contains 400 new illustrations, 700 in all, to better illustrate complex immunology. Covers the very latest in the field, including hot topics such as food allergy and immunotherapy. Includes the latest guidelines from The National Asthma Education and Prevention Program (NAEPP). Utilizes a new, more user-friendly full-color format for easier reference.
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