Vitamin C: A 500-Year Scientific Biography from Scurvy to Pseudoscience is the compelling story of the history and science behind vitamin C. Vitamin C begins with scurvy, which afflicted Europe for four hundred years and killed millions. The reasons that a disease whose cure was known from the outset persisted over that time are at once baffling and familiar, and these trials eventually lead to invention of the science of epidemiology. Author Stephen M. Sagar MD then chronicles the discovery of vitamins at the beginning of the twentieth century, a story that encapsulates the rise of a scientific approach to nutrition but with surprising twists and turns. As vitamin science became more acquainted with the mainstream, scientist Linus Pauling reached new heights of fame and influence by popularizing the practice of taking megadoses of vitamin C to prevent colds – a claim that was not necessarily backed by data. This kickstarted the growth of the $40 billion vitamin and supplement industry, which has since prospered all while ignoring science. This unique and engrossing narrative reveals how medical science functions in the real world and how it has changed over the centuries. Featuring swashbuckling sailors, arctic explorers, penny-pinching bureaucrats, academicians with clashing egos, and intrepid scientists working in malaria-infested jungle laboratories, the story of C is in many ways the story of how science gets done (and undone). From the trial and error of early explorers to the scientific breakthroughs made by biochemists and the birth of the modern supplement industry, this revelatory book tells the story of how cherished beliefs, self-interest, and politics often intertwine with scientific progress.
Vitamin C: A 500-Year Scientific Biography from Scurvy to Pseudoscience is the compelling story of the history and science behind vitamin C. Vitamin C begins with scurvy, which afflicted Europe for four hundred years and killed millions. The reasons that a disease whose cure was known from the outset persisted over that time are at once baffling and familiar, and these trials eventually lead to invention of the science of epidemiology. Author Stephen M. Sagar MD then chronicles the discovery of vitamins at the beginning of the twentieth century, a story that encapsulates the rise of a scientific approach to nutrition but with surprising twists and turns. As vitamin science became more acquainted with the mainstream, scientist Linus Pauling reached new heights of fame and influence by popularizing the practice of taking megadoses of vitamin C to prevent colds – a claim that was not necessarily backed by data. This kickstarted the growth of the $40 billion vitamin and supplement industry, which has since prospered all while ignoring science. This unique and engrossing narrative reveals how medical science functions in the real world and how it has changed over the centuries. Featuring swashbuckling sailors, arctic explorers, penny-pinching bureaucrats, academicians with clashing egos, and intrepid scientists working in malaria-infested jungle laboratories, the story of C is in many ways the story of how science gets done (and undone). From the trial and error of early explorers to the scientific breakthroughs made by biochemists and the birth of the modern supplement industry, this revelatory book tells the story of how cherished beliefs, self-interest, and politics often intertwine with scientific progress.
Introducing the most dramatically revised edition of Harrison's ever! Now with NEW bonus DVD with 37 chapters and more than 500 brand new images and video clips! MORE THAN TRUSTED, BEYOND ESSENTIAL . . . The #1 selling medical textbook worldwide, Harrison's has defined internal medicine for millions of clinicians and students. The new Seventeenth Edition retains Harrison's acclaimed balance of pathobiology, cardinal signs and manifestations of disease, and best approaches to patient management, yet has been massively updated to give you an innovative array of bold new features and content. If ever there was one must-have resource for clinicians and students - this is it! UNMATCHED EXPERTISE AT YOUR FINGERTIPS As an unprecedented amount of medical information bombards you and your patients, where do you go to sort it out and make sense of it all? When your patients request clarification on something they've “printed off” where do you turn for expert explanations? The same trusted resource physicians and students have turned to for over fifty years: Harrison's Principles of Internal Medicine. Now more than ever, trust Harrison's to filter and clarify the exploding knowledge base, to highlight the breakthroughs, and to deliver a clear, balanced distillation of the best and most current information on which to base clinical decisions. THE MOST EXCITING AND EXTENSIVELY REVISED EDITION EVER! Here are just a few of the reasons why the new 17th Edition of Harrison's is the best edition yet: Bonus companion DVD featuring: 37 new “e-chapters”; over 500 brand-new radiological, laboratory, and clinical images, including complete atlases; state-of-the-art video clips; an Image Bank of nearly all the illustrations contained in the parent text, and much more Expanded, modernized illustration program with more than 800 brand-new, additional illustrations-a 60% increase over the previous edition Dozens of brand new chapters on vital topics in medical education and clinical practice: Global Issues in Medicine: Patient Safety and Health Quality; Health Disparities: Atlas of EKGs; Clinical Management of Obesity: Atlas of Hematology: Atlases of Chest, Neurological, and Cardiovascular Radiology, and much more! Also included a complete new Section on biological foundations and emerging clinical applications of regenerative medicine! Brand new, reader-friendly text design optimizes the full-color format An expanded, innovative focus on global health NEW Global Advisory Board comprised of 11 prominent medical experts from Asia, India, Europe, and South America Revision of the popular On Line Learning Center, which offers more skill-sharpening self-assessment questions and answers, plus additional case studies for helping you apply Harrison's content to the daily care of patients Harrison's related products are available in a full suite of formats to meet all your educational and clinical needs. Harrison's Practice of Medicine is a complete database of more than 700 clinical topics formatted for use at the point of care. The Harrison's Manual of Medicine is one of the most popular and heavily used handbook-sized resources in internal medicine. The Harrison's Self-Assessment and Board Review features more than 1000 board-type cases and questions and highlights the use of Harrison's as a great board prep resouce.
Market: Internists and family physicians (100,000), internal medicine and family practice residents (30,000), physician assistants and nurse practitioners (100,000), second, third, and fourth year medical students (18,000), neurologists (6,000)
THE NEW COLOR OF MEDICINE HUNDREDS OF DIAGRAMS AND CLINICAL PHOTOS INTEGRATED INTO THE TEXT – FOR THE FIRST TIME IN FULL COLOR *This description refers to the single-volume of Harrison's Principles of Internal Medicine, 16/e. The Harrison's name is synonymous with internal medicine. HPIM continues to be the most authoritative and #1 selling medical textbook throughout the world. From its unique section on signs and symptoms through to the most comprehensive coverage of most all conditions seen by physician’s, Harrison's is the internal medicine reference of choice. Harrison's 16th Edition features new, expanded, revised and updated material on the key topics in medical practice today. From the latest research findings to up-to-the-minute advances in diagnostic and treatment methodologies, Harrison's puts the facts you need at your fingertips. The 16th Edition improves on a winning formula with: *State-of-the-art coverage of over 4,700 diseases and disorders—more than any other internal medicine text – in the areas of oncology and hematology; infectious diseases; cardiology; pulmonology; gastroenterology; clinical immunology; rheumatology; endocrinology; and neurology *A brand new full color format—665 full color drawings, 175 clinical and laboratory images, and hundreds of boxes, tables, and algorithms that use color to guide you to the information you need ASAP in everyday patient care *Thorough revision and updates of virtually all chapters *The addition of key new chapters – including extensive new coverage of Critical Care Medicine *145 algorithms for making accurate clinical decisions fast at the point of care *1,160 easy-access tables for immediate access to vital information and formulas *Cardinal manifestations of disease/signs and symptoms in 55 chapters (you’ll find yourself turning to this section over and over again). Here you will find all the major manifestations, such as fever, pain, aches and rash, presented in depth, with a referral that takes you to the disease section for the complete chapter. Stay a step ahead of everyday practice with the most authoritative, comprehensive, and useful guide to the entire spectrum of internal medicine.
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