This book provides the first comprehensive review of research that addresses the immunomodulation of gastrointestinal motility. Results from this new field of research are important for understanding motility disturbances and symptom-generation in a variety of clinical gastroenterological problems, including ulcerative colitis, Crohn's disease, enteric infections, and food allergies. The book provides overviews on current perspectives regarding the nature of inflammatory processes, inflammatory mediators, and other immune factors. It also describes a variety of experimental approaches that have been used to study the interactions between immune cells and smooth muscle or enteric nerves. The approaches include in vivo, as well as in vitro studies. Researchers involved in the general field of immunophysiology, as well as the more specific fields of gastrointestinal motility and inflammatory bowel diseases will find this book to be invaluable in their research.
In Black Reconstruction W.E.B. Du Bois wrote, "The slave went free; stood for a brief moment in the sun; then moved back again toward slavery." His words echo across the decades as the civil rights revolution, marked by the passage of landmark civil rights laws in the '60s, has seen those gains steadily and systematically whittled away. As history testifies, revolution nearly always triggers its antithesis: counterrevolution. In this book Steinberg provides an analysis of this backlash, tracing the reverse flow of history that has led to the current national reckoning on race. Steinberg puts counterrevolution into historical and theoretical perspective, exploring the "victim-blaming" and "colorblind" discourses that emerged in the post-segregation era and undermined progress toward racial equality, and led to the gutting of affirmative action. This book reflects Steinberg's long career as a critical race scholar, culminating with his assessment of our current moment and the possibilities for political transformation.
This text, now in its fully-updated third edition, continues to offer a comprehensive synthesis of the key issues associated with tourism, leisure and recreation.
The kidney is an organ with complex organogenesis susceptible to numerous misadventures in development and is exposed to a diverse array of insults of hematogenous and lower urinary tract origin. This Atlas of Medical Renal Pathology provides an overview of the development, macroscopic and microscopic features of the normal kidney. This is followed by a comprehensive survey of developmental and cystic kidney diseases, vascular diseases and tubulointerstitial diseases. An emphasis is placed on gross diagnostic findings with detailed histological correlates. In addition, the histological, immunofluorescent, immunohistochemical and ultrastructural features of the major glomerular diseases and renal transplantation pathology are presented. This compendium of non-neoplastic kidney diseases illustrates the vast majority diseases you are likely to encounter in surgical and autopsy pathology.
Advanced Therapy of Inflammatory Bowel Disease - Second Edition The main emphasis of this new edition is on diagnosis, therapy and patient management, along with disease activity measures, IBD databases, and the use of diagnostic tests in clinical decision making. Each chapter consists of recommendations from an expert in the ......
We have a decade or less to radically slow global warming before we risk hitting irreversible tipping points that will lock in catastrophic climate change. The good news is that we know how to slow global warming enough to avert disaster. Cut Super Climate Pollutants Now! explains how a 10-year sprint to cut short-lived “super climate pollutants” -- primarily HFC refrigerants, black carbon (soot), and methane -- can cut the rate of global warming in half, so we can stay in the race to net zero climate emissions by 2050.
The Geography of Tourism and Recreation presents the first comprehensive introduction to tourism, leisure and recreation and the relationships between them. This accessible text includes a wealth of international case studies spanning Europe, North America, Australasia and China. Each chapter highlights the methods used by geographers to analyse recreation and tourism. It also introduces new perspectives from gender studies and postmodernism and examines key issues including * the demand and supply of recreation and tourism * the role of public policy, planning and management * the impact of tourism and recreation on urban, rural, mountain and coastal environments * tourism and recreation in wilderness areas and other peripheral regions. The use of student text features makes it ideal for course use.
Our Energy Future is an introductory textbook for a college course in energy production, alternative and renewable fuels, and related issues involved in building a sustainable energy future. Our society is consuming energy at an alarming rate as trends in energy consumption continue to rise. Jones and Mayfield explore the creation and history of fossil fuels, their impact on the environment, and how they have become critical to our society. They warn that continuing fuel-usage patterns could permanently damage our environment. Jones and Mayfield also outline how the adoption of sustainable biofuels will be key to our future energy stability. They discuss a number of renewable energy options, and then discuss different biofuel feedstocks and their potential as replacements for petroleum-based products. This book emphasizes the importance of continued scientific, agricultural, and engineering development, while outlining the political and environmental challenges that are coupled with a complete shift from fossil fuels to renewable energy and biomass. Our Energy Future is an excellent, accessible resource for undergraduate students studying biofuels and bioenergy."--Provided by publisher.
Law and Society in England 1750–1950 is an indispensable text for those wishing to study English legal history and to understand the foundations of the modern British state. In this new updated edition the authors explore the complex relationship between legal and social change. They consider the ways in which those in power themselves imagined and initiated reform and the ways in which they were obliged to respond to demands for change from outside the legal and political classes. What emerges is a lively and critical account of the evolution of modern rights and expectations, and an engaging study of the formation of contemporary social, administrative and legal institutions and ideas, and the road that was travelled to create them. The book is divided into eight chapters: Institutions and Ideas; Land; Commerce and Industry; Labour Relations; The Family; Poverty and Education; Accidents; and Crime. This extensively referenced analysis of modern social and legal history will be invaluable to students and teachers of English law, political science, and social history.
The fourth edition of Corporate Finance takes an applied approach to cover all the latest research and topic areas important to students taking Finance courses. The new edition provides an international perspective on all areas of corporate finance and has been updated to include discussion on current trends such as the rise of populism and trade barriers on international finance, the advent of Financial Technology, and key regulatory changes impacting the sector. Understanding and Application •Clear, user-friendly style •Example boxes in every chapter provide hypothetical examples to illustrate theoretical concepts such as cash flow timing, dividend smoothing and differential growth. •Real World Insight boxes use real companies like Siemens, Avast and Adidas to show how they have applied corporate finance theories and concepts to their businesses and business decisions. •Chapter links in the margin provide quick cross-referencing to show students the connections between topics. Practice and Proficiency •Mini and Practical cases present scenarios and questions to practice applying what you have learnt. •Rigorous testing: between 30 and 40 Questions and Problems per chapter are categorised by topic and level of difficulty. •Numbered maths equations and key notation boxes listing the variables and acronyms that will be encountered in each chapter, designed to encourage mastery of Maths. •Exam Questions designed to take 45 minutes and test you on material learned in a more formal exam style. •Connect® resources include algorithmic questions designed to ensure equations and calculations are not learned by rote but by thorough understanding and practice New to This Edition •Updated discussions on peer-to-peer trading, cash flow forecasting methods, import/export partners and additional investment appraisal methods •Updated chapters on corporate governance to reflect global changes, efficient markets and mergers and acquisition to reflect new research, financial distress to reflect new data with discussion on trends and insolvencies and fully updated chapter on Leasing to reflect new IFRS standards •New section on Modified Internal Rate of Return and Margin of Safety in Investment Appraisal, Net Asset Value, Islamic Financing, and alternatives to CAPM to reflect research developments • NEW: This edition has now been updated with 8 new videos that covers a worked example from the text and each video has associated concept check questions. The videos are now available on Connect® and cover: • Chapter 1 & 2: Introduction to Finance and Corporate Governance • Chapter 5: Long-Term Financing • Chapter 6: Investment Appraisal • Chapter 9 & 10: Risk and Return • Chapter 15 and 16: Equity and Debt Valuation • Chapter 20: Advanced Capital Budgeting • Chapter 21: Dividends • Chapter 22: Options David Hillier is Associate Principal and Executive Dean of the University of Strathclyde Business School. A Professor of Finance, David was recognized as being in the top 3 per cent of the most prolific finance researchers in the world over the past 50 years (Heck and Cooley, 2009) and appears regularly in the media as a business commentator.
With this fully revised fourth edition, Dr Stahl returns to the essential roots of what it means to become a neurobiologically empowered psychopharmacologist, expertly guided in the selection and combination of treatments for individual patients in practice. Embracing the unifying themes of 'symptom endophenotypes', dimensions of psychopathology that cut across syndromes, and 'symptoms and circuits', every aspect of the text has been updated to the frontiers of current knowledge, with the clarity of explanation and illustration that only Dr Stahl can bring. Integrating much of the basic neuroscience into the clinical chapters, and with major additions in the areas of psychosis, antipsychotics, antidepressants, impulsivity, compulsivity and addiction, this is the single most readily readable source of information on disease and drug mechanisms. This remains the essential text for all students and professionals in mental health seeking to understand and utilize current therapeutics, and to anticipate the future for novel medications.
Fully updated for its Fifth Edition, Principles and Practice of Psychopharmacotherapy summarizes the latest data on hundreds of drug and device-based therapies and offers practical, evidence-based guidelines and treatment strategies for virtually every psychiatric disorder. Highlights of this edition include expanded coverage of pharmacogenomics, updates on treatments for elderly patients, and discussion of mechanisms of action for drugs used in sleep disorders, especially narcolepsy.
This will help us customize your experience to showcase the most relevant content to your age group
Please select from below
Login
Not registered?
Sign up
Already registered?
Success – Your message will goes here
We'd love to hear from you!
Thank you for visiting our website. Would you like to provide feedback on how we could improve your experience?
This site does not use any third party cookies with one exception — it uses cookies from Google to deliver its services and to analyze traffic.Learn More.