Stephen Greenblatt argued in these celebrated essays that the art of the Renaissance could only be understood in the context of the society from which it sprang. His approach - 'New Historicism' - drew from history, anthropology, Marxist theory, post-structuralism, and psychoanalysis and in the process, blew apart the academic boundaries insulating literature from the world around it. Learning to Curse charts the evolution of that approach and provides a vivid and compelling exploration of a complex and contradictory epoch.
This authoritative, timely, and comprehensively referenced compendium on the bacteriophages explores current views of how viruses infect bacteria. In combination with classical phage molecular genetics, new structural, genomic, and single-molecule technologies have rendered an explosion in our knowledge of phages. Bacteriophages, the most abundant and genetically diverse type of organism in the biosphere, were discovered at the beginning of the 20th century and enjoyed decades of used as anti-bacterial agents before being eclipsed by the antibiotic era. Since 1988, phages have come back into the spotlight as major factors in pathogenesis, bacterial evolution, and ecology. This book reveals their compelling elegence of function and their almost inconceivable diversity. Much of the founding work in molecular biology and structural biology was done on bacteriophages. These are widely used in molecular biology research and in biotechnology, as probes and markers, and in the popular method of assesing gene expression.
Stephen Greenblatt argued in these celebrated essays that the art of the Renaissance could only be understood in the context of the society from which it sprang. His approach - 'New Historicism' - drew from history, anthropology, Marxist theory, post-structuralism, and psychoanalysis and in the process, blew apart the academic boundaries insulating literature from the world around it. Learning to Curse charts the evolution of that approach and provides a vivid and compelling exploration of a complex and contradictory epoch.
In the eight years since the publication of the second edition of this Guide, psycho phannacotherapy has made many advances not only through the discovery of new medications but by the effective directing of their use to an ever-increasing variety of clinical disorders. These welcome developments are reflected in the concurrent growth and development of the Guide itself, which now enters adulthood with renewed vigor. Under the thoughtful and scholarly leadership of Dr. Alan Gelenberg, the third edition has undergone a significant transformation designed to meet the needs of the modem clinician. The panel of contributors is nearly double that of the former edition with the addition of nine new authors, who have helped in the major revision and rewriting of the text and in a broadening of the topics included. As a conse quence, the reader is assured of a thorough and thoroughly up-to-date coverage of current psychopharmacology that is both accurate and aimed at clinical utility. Having reached maturity, the third edition, while maintaining the lineaments of its earlier versions, is a considerably expanded and strengthened guide to treatment. Although now more encyclopedic in content, the new Practitioner' s Guide to Psy choactive Drugs retains the virtues of a clinical vade mecum that informed its predecessors and have eamed it a place by the patient's bedside for weIl over a decade. One may confidently anticipate its long and flourishing career in the years ahead. John C. Nemiah, M.D.
The sixteen essays assembled in this volume, four of them co-authored, chart the successive phases of a professional life lived in the interstices of Bible and "theory." Engaging such texts as the Song of Songs, 4 Maccabees, Mark, Luke-Acts, John, and Romans, and such themes as the quest for the historical Jesus, the essays simultaneously traverse postmodernism, deconstruction, New Historicism, autobiographical criticism, cultural studies, postcolonial studies, masculinity studies, queer theory, and "posttheory." Individual essay introductions and periodic annotated bibliographies make the volume an advanced introduction to biblical literary criticism. --From publisher's description.
Renaissance Self-Fashioning is a study of sixteenth-century life and literature that spawned a new era of scholarly inquiry. Stephen Greenblatt examines the structure of selfhood as evidenced in major literary figures of the English Renaissance—More, Tyndale, Wyatt, Spenser, Marlowe, and Shakespeare—and finds that in the early modern period new questions surrounding the nature of identity heavily influenced the literature of the era. Now a classic text in literary studies, Renaissance Self-Fashioning continues to be of interest to students of the Renaissance, English literature, and the new historicist tradition, and this new edition includes a preface by the author on the book's creation and influence. "No one who has read [Greenblatt's] accounts of More, Tyndale, Wyatt, and others can fail to be moved, as well as enlightened, by an interpretive mode which is as humane and sympathetic as it is analytical. These portraits are poignantly, subtly, and minutely rendered in a beautifully lucid prose alive in every sentence to the ambivalences and complexities of its subjects."—Harry Berger Jr., University of California, Santa Cruz
Fully updated for its Fifth Edition, Principles and Practice of Psychopharmacotherapy summarizes the latest data on hundreds of drug and device-based therapies and offers practical, evidence-based guidelines and treatment strategies for virtually every psychiatric disorder. Highlights of this edition include expanded coverage of pharmacogenomics, updates on treatments for elderly patients, and discussion of mechanisms of action for drugs used in sleep disorders, especially narcolepsy.
This new book provides a unified, in-depth, readable introduction to the multipredictor regression methods most widely used in biostatistics: linear models for continuous outcomes, logistic models for binary outcomes, the Cox model for right-censored survival times, repeated-measures models for longitudinal and hierarchical outcomes, and generalized linear models for counts and other outcomes. Treating these topics together takes advantage of all they have in common. The authors point out the many-shared elements in the methods they present for selecting, estimating, checking, and interpreting each of these models. They also show that these regression methods deal with confounding, mediation, and interaction of causal effects in essentially the same way. The examples, analyzed using Stata, are drawn from the biomedical context but generalize to other areas of application. While a first course in statistics is assumed, a chapter reviewing basic statistical methods is included. Some advanced topics are covered but the presentation remains intuitive. A brief introduction to regression analysis of complex surveys and notes for further reading are provided.
Drug Disposition and Pharmacokinetics The most up-to-date edition of a leading reference in drug disposition and pharmacokinetics In this new, fully-revised edition of Drug Disposition and Pharmacokinetics: Principles and Applications for Medicine, Toxicology and Biotechnology the authors deliver an authoritative and comprehensive discussion of the fate of drug molecules in the body, as well as its implications for pharmacological and clinical effects. The text offers a unique and balanced approach that combines discussion of the specific physical and biological factors affecting the absorption, distribution, metabolism, and excretion of drugs, with mathematical assessments of plasma and body fluid concentrations. The book assumes little prior knowledge and is an ideal reference for practicing professionals in industry as well as researchers and academics. This latest edition provides readers with a new introductory chapter, as well as new chapters covering monoclonal antibodies, the role of stereochemistry in drug disposition and pharmacokinetics, DMPK in non-human species, and the recent use of AI in drug development. Readers will also find: Thorough introductions to drug disposition, pharmacokinetics, and pharmacokinetic modeling In-depth treatments of the kinetics of drug elimination and the relationship between concentration and effect, including PK–PD modeling Comprehensive discussions of predictive pharmacokinetics and the disposition of biological molecules, including peptides and monoclonal antibodies Detailed examinations of the effects of sex, pregnancy, age, and disease, as well as drug monitoring in therapeutics and the use of AI in drug development and treatment Perfect for professionals and researchers working with the scientific aspects of drug disposition in human and veterinary medicine, toxicology, and pharmacology. Drug Disposition and Pharmacokinetics will earn a place in the libraries of students of senior-level courses in pharmacy.
A portrait of Elizabethan England and how it contributed to the making of William Shakespeare discusses how he moved to London lacking money, connections, and a formal education and rose to became his age's foremost playwright.
Handbook on ERISA Litigation cuts through complicated statutory provisions andtells you which ERISA claims are recognized by which courts and how tolitigate them.
Reconceptualizing the Literacies in Adolescents' Lives, Second Edition focuses on exploring the impact of young people's identity-making practices in mediating their perceptions of themselves as readers and writers in an era of externally mandated reforms. What is different in the Second Edition is its emphasis on the importance of valuing adolescents' perspectives--in an era of skyrocketing interest in improving literacy instruction at the middle and high school levels driven by externally mandated reforms and accountability measures. A central concern is the degree to which this new interest takes into account adolescents’ personal, social, and cultural experiences in relation to literacy learning. In this new edition of Reconceptualizing the Literacies in Adolescents’ Lives students’ voices and perspectives are featured front and center in every chapter. Particular attention is given throughout to multiple literacies--especially how information and new communication technologies are changing learning from and with text. Nine of the 15 chapters are new; all other chapters are thoroughly updated. The volume is structured around four main themes: * Situating Adolescents’ Literacies–addressing how young people use favorite texts to perform their identities; how they counter school-based constructions of incompetence; and how they re/construct their literate identities in relation to certain kinds of gendered expectations, pedagogies, and cultural resources; * Positioning Youth as Readers and Writers–stressing the importance of classroom discourse, cultural capital, agency, and democratic citizenship in mediating adolescents’ literate identities; * Mediating Practices in Young People’s Literacies–looking at issues of language, social class, race, and culture in shaping how adolescents represent themselves and are represented by others; and * Changing Teachers, Teaching Changes–capturing the productive ambiguities associated with teaching urban adolescents to read and write in changing times, encouraging students to conduct action research on topics that are personally relevant, and using ‘enabling constraints’ as a concept to formulate policies on adolescent literacy instruction. Reconceptualizing the Literacies in Adolescents’ Lives, Second Edition is an essential volume for researchers, faculty, teacher educators, and graduate students in the field of adolescent literacy education.
Now established as the indispensable formulary in psychopharmacology, this latest edition of The Prescriber's Guide has been completely revised and updated to reflect the most current practice in the use of psychotropic drugs. Easy to navigate and easy to use, The Prescriber's Guide combines evidence-based information with clinically informed guidance to support clinicians in making the most effective prescribing decisions for the good of their patients. With coverage of twelve brand-new drugs – including antidepressants, antipsychotics, hypnotics, nonstimulants for ADHD and medical foods – and incorporating information on the newest indications, new formulations, new recommendations and new safety data, this edition continues to provide the essential practical support required by anyone prescribing in the field of mental health.
This completely revised and updated edition of Stephen M. Stahl's much-acclaimed Prescriber's Guide is the latest addition to the Essential Psychopharmacology range. Seven new drugs have been added, and every drug has been revised and updated to take into account new regulations and uses. In full color throughout, and with four or more pages for each of the more than 100 psychotropic drugs, Stephen M. Stahl distills his great expertise into a pragmatic formulary that gives all the information a prescriber needs to treat patients effectively. Each drug is covered in five categories: general therapeutics, dosing and use, side effects, special populations, and pearls. Target icons appear next to key categories for each drug so the prescriber can go easily and instantly to the information needed. Several indices are included, listing drugs by name (generic and international), use, and class. In addition, Dr. Stahl indicates which drugs have FDA approval and also gives the FDA Use-in-Pregnancy Ratings.
The music of Gustav Mahler repeatedly engages with Romantic notions of redemption. This is expressed in a range of gestures and procedures, shifting between affirmative fulfilment and pessimistic negation. In this groundbreaking study, Stephen Downes explores the relationship of this aspect of Mahler's music to the output of Benjamin Britten, Kurt Weill and Hans Werner Henze. Their initial admiration was notably dissonant with the prevailing Zeitgeist - Britten in 1930s England, Weill in 1920s Germany and Henze in 1950s Germany and Italy. Downes argues that Mahler's music struck a profound chord with them because of the powerful manner in which it raises and intensifies dystopian and utopian complexes and probes the question of fulfilment or redemption, an ambition manifest in ambiguous tonal, temporal and formal processes. Comparisons of the ways in which this topic is evoked facilitate new interpretative insights into the music of these four major composers.
Molecular Biology is a rapidly advancing field with a constant flow of new information and cutting-edge developements that impact our lives. Lewin's GENES has long been the essential resource for providing the teaching community with the most modern presentation to this dynamic area of study. GENES XI continues this tradition by introducing the most current data from the field, covering gene structure, sequencing, organization, and expression. It has enlisted a wealth of subject-matter experts, from top institutions, to provide content updates and revisions in their individual areas of study. A reorganized chapter presentation provides a clear, more student-friendly introduction to course material than ever before. - Updated content throughout to keep pace with this fast-paced field.- Reorganized chapter presentation provides a clear, student-friendly introduction to course material.- Expanded coverage describing the connection between replication and the cell cycle is included, and presents eukaryotes as well as prokaryotes.- Available with new online Molecular Biology Animations.- Online access code for the companion website is included with every new book. The companion website offers numerous study aids and learning tools to help students get the most out of their course.- Instructor's supplements include: PowerPoint Image Bank, PowerPoint Lecture Slides, and Test Bank.
While many introductory public administration textbooks contain a dedicated chapter on ethics, The Public Administration Profession is the first to utilize ethics as a lens for understanding the discipline. Analyses of the ASPA Code of Ethics are deftly woven into each chapter alongside complete coverage of the institutions, processes, concepts, persons, history, and typologies a student needs to gain a thorough grasp of public service as a field of study and practice. Features include: A significant focus on "public interests," nonprofit management, hybrid-private organizations, contracting out and collaborations, and public service at state and local levels. A careful examination of the role that religion may play in public servants’ decision making, as well as the unignorable and growing role that faith-based organizations play in public administration and nonprofit management at large. End-of-chapter ethics case studies, key concepts and persons, and dedicated "local community action steps" in each chapter. Appendices dedicated to future public administration and nonprofit career management, writing successful papers throughout a student’s career, and professional codes of ethics. A comprehensive suite of online supplements, including: lecture slides; quizzes and sample examinations for undergraduate and graduate courses containing multiple choice, true-false, identifications, and essay questions; chapter outlines with suggestions for classroom discussion; and suggestions for use of appendices, e.g., how to successfully write a short term paper, a brief policy memo, resume, or a book review. Providing students with a comprehensive introduction to the subject while offering instructors an elegant new way to bring ethics prominently into the curriculum, The Public Administration Profession is an ideal introductory text for public administration and public affairs courses at the undergraduate or graduate level.
This third edition provides a comprehensive, colorful, up-to-date, and accessible presentation of AI without sacrificing theoretical foundations. It includes numerous examples, applications, full color images, and human interest boxes to enhance student interest. New chapters on deep learning, AI security, and AI programming are included. Advanced topics cover neural nets, genetic algorithms, natural language processing, planning, and complex board games. A companion disc is provided with resources, applications, and figures from the book. Numerous instructors’ resources are available upon adoption. Features: • Includes new chapters on deep learning, AI security, and AI programming • Provides a comprehensive, colorful, up to date, and accessible presentation of AI without sacrificing theoretical foundations • Uses numerous examples, applications, full color images, and human interest boxes to enhance student interest • Introduces important AI concepts e.g., robotics, use in video games, neural nets, machine learning, and more thorough practical applications • Features over 300 figures and color images with worked problems detailing AI methods and solutions to selected exercises • Includes companion files with resources, simulations, and figures from the book • Provides numerous instructors’ resources, including: solutions to exercises, Microsoft PP slides, etc. The companion files are available online by emailing the publisher with proof of purchase at info@merclearning.com.
In this "tale of two disciplines," Stephen D. Moore and Yvonne Sherwood invite the reader into a paradox: just as the wider field of literary studies has now come to operate "after theory," biblical scholars continue their long search for an elusive Holy Grail?a definitive literary-critical theory. Understanding that paradox requires revisiting the peculiar history by which the curious figure of the biblical scholar was invented during the Enlightenment, and how contemporary biblical scholarship continues?however unwittingly?to pursue Enlightenment goals.
Is the American judiciary still the least dangerous branch, as Alexander Hamilton and legal scholar Alexander Bickel characterized it? Unlike legislatures or administrative agencies, courts do not make policy so much as direct and redirect policy as it is implemented. The judicial contribution to policymaking involves the infusion of constitutional rights into the realm of public policy, and as the government has grown, the courts have become more powerful from doing more and more of this. Powers and Rothman explore the impact of the federal courts, providing a brief account of the development of constitutional law and an overview of the judiciary's impact in six controversial areas of public policy. •Busing •Affirmative action •Prison reform •Mental health reform •Procedural reforms in law enforcement •Electoral redistricting In each of these areas, the authors review significant cases that bear on the particular policy, exploring the social science evidence to assess the impact of the courts on policies—and the consequences of that intervention. Powers and Rothman conclude that judicial intervention in public policy has often brought about undesirable consequences, sometimes even for the intended beneficiaries of government intervention.
Now in its twelfth edition, Lewin's GENES continues to lead with new information and cutting-edge developments, covering gene structure, sequencing, organization, and expression. Leading scientists provide revisions and updates in their individual field of study offering readers current data and information on the rapidly changing subjects in molecular biology.
This Gold Standard in clinical child neurology presents the entire specialty in the most comprehensive, authoritative, and clearly written fashion. Its clinical focus, along with relevant science, throughout is directed at both the experienced clinician and the physician in training. New editor, Dr. Ferriero brings expertise in neonatal neurology to the Fourth Edition. New chapters: Pathophysiology of Hypoxic Ischemic Encephalopathy, Congenital Disorders of Glycosylation, Pediatric Neurotransmitter Diseases, Neurophysiology of Epilepsy, Genetics of Epilepsy, Pediatric Neurorehabilitation Medicine, Neuropsychopharmacology, Pain and Palliative Care Management, Ethical Issues in Child Neurology
Confidently diagnose, treat, and manage patient conditions with the only comprehensive book on the market devoted solely to equine internal medicine. Filled with fully updated content on principles of treatment and contributions from internationally known equine experts, Equine Internal Medicine, 4th Edition focuses on the basic pathophysiologic mechanisms that underlie the development of various equine diseases. A problem-based approach outlines how to apply the latest clinical evidence directly to the conditions you will encounter in practice. A new companion website with over 120 video clips presents diseases and disorders that cannot be explained as well through words - Updated information throughout, including the most recent drug information. Current and well-referenced content on equine diseases and treatment techniques cites the latest books and journals. - Internationally known equine experts present information on problems affecting horses throughout the world — and provide contributions that enable practitioners and students to approach disease and treatment of equine patients with more authority and understanding. - User-friendly exterior and interior design makes the book appealing to both the equine internal medicine practitioner and the veterinary student. Easy-to-find information facilitates a more thorough understanding with minimal frustration. - Organized and consistent coverage among chapters allows you to easily find information on a specific topic. - NEW! Fully updated and revised sections on disorders and principles of treatment. - NEW! Problem-based approach outlines how to apply the latest clinical evidence directly to the conditions you will encounter in practice. - NEW! Pathophysiology is emphasized throughout, providing a sound basis for discussions of the diagnosis, treatment, and prognosis that follow. - NEW! Body systems chapters begin with a thorough discussion of the diagnostic method appropriate to the system, including physical examination, clinical pathology, radiography, endoscopy, and ultrasonography. - NEW and UNIQUE! Companion website includes more than 120 video clips linked to content from chapters on cardiovascular and neurologic system disorders. - NEW! Flow charts, diagrams, and algorithms clarify complex material.
There are two basic rules for writing nonfiction, says historian and award-winning author Stephen J. Pyne. Rule 1: You can’t make stuff up. Rule 2: You can’t leave out known stuff that affects our understanding. Follow these rules, and you are writing nonfiction. Writing for different audiences and genres will require further guidelines. But all readers expect that style and story (or more broadly, theme) will complement one another. Style and Story is for those who wish to craft nonfiction texts that do more than simply relay facts and arguments. Pyne explains how writers can employ literary tools and strategies to have art and craft add value to their theme. With advice gleaned from nearly a dozen years of teaching writing to graduate students, Pyne offers pragmatic guidance on how to create powerful nonfiction, whether for an academic or popular audience. Each chapter offers samples that span genres, showcasing the best kinds of nonfiction writing. Pyne analyzes these examples that will help writers understand how they can improve their nonfiction through their choice of voice, words, structure, metaphors, and narrative. Pyne builds on his previous guide, Voice and Vision, expanding the range of topics to include openings and closings, humor and satire, historical writing, setting scenes, writing about technical matters and deep details, long and short narration, reading for craft, and thoughts on writing generally. He also includes in this volume a set of exercises to practice writing techniques. Style and Story will be treasured by anyone, whether novice or expert, who seeks guidance to improve the power of their nonfiction writing.
Your days spent fruitlessly scouring textbooks and websites for credible vet information are over! Now you can get the whole story — the accurate story — all in one place. Introducing The Textbook of Veterinary Internal Medicine, Expert Consult, 8th Edition. Still the only comprehensive resource for veterinary internal medical problems, this faculty-and-student-favorite offers unparalleled coverage of pathophysiology, diagnosis, and disease treatments for dogs and cats. In addition to new chapters and discussions on the industry’s most topical issues, this "gold standard in vet medicine" comes with hundreds of original videos, algorithms, and learning tools to really bring all the information to life. There’s no better source to help you unlock the secrets of veterinary medicine than Ettinger’s! Fully searchable online text offers quick access to the most trusted information in the field. Complete library of over 500 original clinical videos you can believe in. Instead of fruitless YouTube searches, each video expertly breaks down veterinary procedures and important signs of diseases and disorders that are difficult or impossible to understand from written descriptions alone. In-depth coverage of timely issues includes expert explanations on topics such as the genome, clinical genomics, euthanasia, innocent heart murmurs, hyperbaric medicine, home prepared and raw diets, obesity, botulism, artificial pacing of the heart, and cancer vaccines. Thousands of references accessible from the printed book with the click of a QR code. 256 all-new client information sheets can be downloaded, customized, and printed as client handouts. 214 new and updated clinical algorithms aid in disease identification and decision-making. Exclusive access to Expert Consult Online website offers the complete library of original video clips, heart sounds, the full collection of client information sheets, and hyperlinking of references to their source abstracts in PubMed. NEW! In-depth coverage of the latest information and trends in small animal internal medicine. Completely new section on minimally-invasive interventional procedures includes techniques for treating respiratory, cardiovascular, gastrointestinal, urologic/nephrologic, and neoplastic disorders. 17 new chapters address the major clinicopathologic abnormalities that occur in canine and feline laboratory testing. Completely new section on management of mutually-antagonistic comorbidities spotlights concurrent cardiac and renal disease, concurrent infection in patients requiring immunosuppression, and concurrent diabetes mellitus and corticosteroid-dependent disease. Expert explanations on topics such as evidence-based medicine, distinguishing behavioral disorders from medical neurologic disorders, blood transfusion techniques, hyperadrenocorticism (Cushing’s disease), chronic kidney disease, respiratory and inhalant therapy, and many more.
Public health surveillance is the systematic, ongoing assessment of the health of a community, based on the collection, interpretation, and use of health data. Surveillance provides information necessary for public health decision making and interventions. In the third edition of Principles and Practice of Public Health Surveillance, the editors present an organized approach to planning, developing, and implementing public health surveillance systems in response to the rapidly changing field of public health. Substantially revised and expanded on, this edition continues to examine further the expansion of surveillance of disease and health determinants, as well as the recent advances in data management and informatics. Major sections of the book focus on bioresponse and preparedness, risk behaviors, and environmental exposure, while the ethical considerations and policy justification for public health surveillance are also explored. Drawing largely from the experience of the Centers for Disease Control and Prevention and other experts in the field, this book provides an excellent framework that collectively improves the surveillance foundation of public health. It will continue to serve as the standard text in the field, an invaluable resource for public health students and the desk reference for public health practitioners.
Explaining the English Revolution studies the years 1649 to 1653, from regicide to the establishment of the Cromwellian Commonwealth, during which time English writers 'took stock' of a disordered England stripped of the traditional ideas of political, moral, and social order and considered the possibilities for a politically and religiously reordered state.
Since 1975, Dr. Kenneth Swaiman's classic text has been the reference of choice for authoritative guidance in pediatric neurology, and the 6th Edition continues this tradition of excellence with thorough revisions that bring you fully up to date with all that's new in the field. Five new sections, 62 new chapters, 4 new editors, and a reconfigured format make this a comprehensive and clearly-written resource for the experienced clinician as well as the physician-in-training. - Nearly 3,000 line drawings, photographs, tables, and boxes highlight the text, clarify key concepts, and make it easy to find information quickly.
Facilitates a rapprochement between psychology and physics. Brings measurement and mathematics into the study of the mind. This detailed and engaging account fills a deep gap in the history of psychology.
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