The 5th edition of this popular introduction to statistics for the medical and health sciences has undergone a significant revision, with several new chapters added and examples refreshed throughout the book. Yet it retains its central philosophy to explain medical statistics with as little technical detail as possible, making it accessible to a wide audience. Helpful multi-choice exercises are included at the end of each chapter, with answers provided at the end of the book. Each analysis technique is carefully explained and the mathematics kept to minimum. Written in a style suitable for statisticians and clinicians alike, this edition features many real and original examples, taken from the authors' combined many years' experience of designing and analysing clinical trials and teaching statistics. Students of the health sciences, such as medicine, nursing, dentistry, physiotherapy, occupational therapy, and radiography should find the book useful, with examples relevant to their disciplines. The aim of training courses in medical statistics pertinent to these areas is not to turn the students into medical statisticians but rather to help them interpret the published scientific literature and appreciate how to design studies and analyse data arising from their own projects. However, the reader who is about to design their own study and collect, analyse and report on their own data will benefit from a clearly written book on the subject which provides practical guidance to such issues. The practical guidance provided by this book will be of use to professionals working in and/or managing clinical trials, in academic, public health, government and industry settings, particularly medical statisticians, clinicians, trial co-ordinators. Its practical approach will appeal to applied statisticians and biomedical researchers, in particular those in the biopharmaceutical industry, medical and public health organisations.
Provides students and practitioners with a clear, conciseintroduction to the statistics they will come across in theirregular reading of clinical papers. Written by three experts with wide teaching and consultingexperience, Medical Statistics: A Textbook for the HealthSciences, Fourth Edition: Assumes no prior knowledge of statistics Covers all essential statistical methods Completely revised, updated and expanded Includes numerous examples and exercises on the interpretationof the statistics in papers published in medical journals From the reviews of the previous edition: "The book has several excellent features: it is written bystatisticians, is.... well presented, is well referenced.... and isshort." THE LANCET "Many statisticians are concerned at the generally poorstandard of statistics in papers published in medical journals.Perhaps this could be remedied if more research workers would sparea few hours to read through Campbell and Machin's book."BRITISH MEDICAL JOURNAL "... a simple, interesting and insightful introduction tomedical statistics... highlyrecommended." STATISTICAL METHODS IN MEDICALRESEARCH "Campbell and Machin found the golden mean... this book canbe recommended for all students and all medicalresearchers." ISCB NEWSLETTER
A complete guide to understanding cluster randomised trials Written by two researchers with extensive experience in the field, this book presents a complete guide to the design, analysis and reporting of cluster randomised trials. It spans a wide range of applications: trials in developing countries, trials in primary care, trials in the health services. A key feature is the use of R code and code from other popular packages to plan and analyse cluster trials, using data from actual trials. The book contains clear technical descriptions of the models used, and considers in detail the ethics involved in such trials and the problems in planning them. For readers and students who do not intend to run a trial but wish to be a critical reader of the literature, there are sections on the CONSORT statement, and exercises in reading published trials. Written in a clear, accessible style Features real examples taken from the authors’ extensive practitioner experience of designing and analysing clinical trials Demonstrates the use of R, Stata and SPSS for statistical analysis Includes computer code so the reader can replicate all the analyses Discusses neglected areas such as ethics and practical issues in running cluster randomised trials How to Design, Analyse and Report Cluster Randomised Trials in Medicine and Health Related Research provides an excellent reference tool and can be read with profit by statisticians, health services researchers, systematic reviewers and critical readers of cluster randomised trials.
An essential, up-to-date guide to the design of studies and selection of the correct QoL instruments for observational studies and clinical trials. Quality of Life (QoL) outcomes or Person/Patient Reported Outcome Measures (PROMs) are now frequently being used in randomised controlled trials (RCTs) and observational studies. This book provides a practical guide to the design, analysis and interpretation of studies that use such outcomes. QoL outcomes tend to generate data with discrete, bounded and skewed distributions. Many investigators are concerned about the appropriateness of using standard statistical methods to analyse QoL data and want guidance on what methods to use. QoL outcomes are frequently used in cross-sectional surveys and non-randomised health-care evaluations. Provides a user-friendly guide to the design and analysis of clinical trials and observational studies in relation to QoL outcomes. Discusses the problems caused by QoL outcomes and presents intervention options to help tackle them. Guides the reader step-by-step through the selection of appropriate QoLs. Features exercises and solutions and a supporting website providing downloadable data files. Illustrated throughout with examples and case studies drawn from the author’s experience, this book offers statisticians and clinicians guidance on choosing between the numerous available QoL instruments.
Effective data presentation is an essential skill for anybody wishing to display or publish research results, but when done badly, it can convey a misleading or confusing message. This new addition to the popular “How to” series explains how to present data in journal articles, grant applications or research presentations clearly, accurately and logically, increasing the chances of successful publication.
The fourth edition of this internationally acclaimed, seminal textbook on the subject of clinical pediatric urology is completely updated. World-renowned experts in the field present state-of-the-art developments in all areas of clinical pediatric urology, from diagnosis to treatment and from theory to practice. Clinical Pediatric Urology is clinical in orientation and practical in presentation, covering every illness, diagnostic method and appropriate treatment in pediatric urology from the embryo onwards. Each chapter is lavishly illustrated with full color photographs and medical artwork. Tables, graphs and charts lend further support to the detailed and comprehensive text, all in a single, easily accessed volume. This is a useful and informative reference for students and specialists alike.
In The Politics of Myth, Stephen Knight studies nine figures still vividly alive, all of them appearing in twenty-first century film and television. Analysing how they relate to the major themes of Power, Resistance and Knowledge, he shows how fact and fiction mix to help us explore and understand the complexities of our world. Surprising mythic shifts occur across time. Robin Hood can be a tough anti-authoritarian, a genial aristocrat, a Saxon patriot; Queen Elizabeth I has been seen as a Protestant heroine, a love-lorn lady, even a grumpy manipulator. From Merlin's multiple manifestations and Sherlock Holmes's smoking habits to the ongoing arguments about Ned Kelly, this book explores the richness and the range of figures of myth.
Nova Scotia is one of Canada's most exciting and picturesque holiday destinations. This guidebook puts its best and most beautiful attractions at your fingertips. The completely revised fifth edition of this popular guide features new sections on the province's rich natural and cultural attractions -- sea kayaking, hiking, the best beaches and golf courses, museums and craft shops -- written by more than a dozen local experts. The emphasis is on cultural and heritage attractions carefully selected for the discriminating visitor. Also included are listings for accommodation, shopping, restaurants and visitor attractions, all with full website information, as well as useful travel information on transport, customs, and much more.
Provides students and practitioners with a clear, conciseintroduction to the statistics they will come across in theirregular reading of clinical papers. Written by three experts with wide teaching and consultingexperience, Medical Statistics: A Textbook for the HealthSciences, Fourth Edition: Assumes no prior knowledge of statistics Covers all essential statistical methods Completely revised, updated and expanded Includes numerous examples and exercises on the interpretationof the statistics in papers published in medical journals From the reviews of the previous edition: "The book has several excellent features: it is written bystatisticians, is.... well presented, is well referenced.... and isshort." THE LANCET "Many statisticians are concerned at the generally poorstandard of statistics in papers published in medical journals.Perhaps this could be remedied if more research workers would sparea few hours to read through Campbell and Machin's book."BRITISH MEDICAL JOURNAL "... a simple, interesting and insightful introduction tomedical statistics... highlyrecommended." STATISTICAL METHODS IN MEDICALRESEARCH "Campbell and Machin found the golden mean... this book canbe recommended for all students and all medicalresearchers." ISCB NEWSLETTER
An essential, up-to-date guide to the design of studies and selection of the correct QoL instruments for observational studies and clinical trials. Quality of Life (QoL) outcomes or Person/Patient Reported Outcome Measures (PROMs) are now frequently being used in randomised controlled trials (RCTs) and observational studies. This book provides a practical guide to the design, analysis and interpretation of studies that use such outcomes. QoL outcomes tend to generate data with discrete, bounded and skewed distributions. Many investigators are concerned about the appropriateness of using standard statistical methods to analyse QoL data and want guidance on what methods to use. QoL outcomes are frequently used in cross-sectional surveys and non-randomised health-care evaluations. Provides a user-friendly guide to the design and analysis of clinical trials and observational studies in relation to QoL outcomes. Discusses the problems caused by QoL outcomes and presents intervention options to help tackle them. Guides the reader step-by-step through the selection of appropriate QoLs. Features exercises and solutions and a supporting website providing downloadable data files. Illustrated throughout with examples and case studies drawn from the author’s experience, this book offers statisticians and clinicians guidance on choosing between the numerous available QoL instruments.
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