This issue of Cardiology Clinics, edited by Dr. Stephen Nicholls, focuses on Lipidology. Topics include, but are not limited to: Impact of lipoproteins on atherobiology; Lessons from genomic studies; Lipids and lipoproteins in risk prediction; Optimizing statins and ezetimibe in guideline focused management; Statin intolerance; Lipid lowering agents and diabetes risk; PCSK9 inhibitors; Bempedoic Acid; Triglyceride rich lipoproteins; Omega 3 Fatty Acids; Lipoprotein; CETP inhibitors; HDL infusions; and Targeting HDL functionality.
Edited by two cardiovascular directors and featuring over 30 contributors, Cardiovascular Imaging for Clinical Practice is an essential guide for cardiologists-on-the-go. This handy, paperback text provides current information on how to incorporate imaging modalities into clinical practice. Presented in an easy-to-read format for quick reference and comprehension, Cardiovascular Imaging for Clinical Practices features clinical scenarios for practical application and over 200 photos and illustrations. Accessible, informative, compact, Cardiovascular Imaging for Clinical Practices is the perfect reference for busy healthcare professionals!
Practical Approach to Diagnosis & Management of Lipid Disorders is a useful guide designed to assist physicians in making an accurate assessment and developing a comprehensive treatment plan for patients with lipid disorders. This concise and informative manual covers key topics such as regulation of lipids and their role in atherosclerosis, clinical approach to evaluation, therapeutic approaches, management of specific patient populations, and the role of imaging modalities.
Managing the Drug Discovery Process, Second Edition thoroughly examines the current state of pharmaceutical research and development by providing experienced perspectives on biomedical research, drug hunting and innovation, including the requisite educational paths that enable students to chart a career path in this field. The book also considers the interplay of stakeholders, consumers, and drug firms with respect to a myriad of factors. Since drug research can be a high-risk, high-payoff industry, it is important to students and researchers to understand how to effectively and strategically manage both their careers and the drug discovery process. This new edition takes a closer look at the challenges and opportunities for new medicines and examines not only the current research milieu that will deliver novel therapies, but also how the latest discoveries can be deployed to ensure a robust healthcare and pharmacoeconomic future. All chapters have been revised and expanded with new discussions on remarkable advances including CRISPR and the latest gene therapies, RNA-based technologies being deployed as vaccines as well as therapeutics, checkpoint inhibitors and CAR-T approaches that cure cancer, diagnostics and medical devices, entrepreneurship, and AI. Written in an engaging manner and including memorable insights, this book is aimed at anyone interested in helping to save countless more lives through science. A valuable and compelling resource, this is a must-read for all students, educators, practitioners, and researchers at large—indeed, anyone who touches this critical sphere of global impact—in and around academia and the biotechnology/pharmaceutical industry. Considers drug discovery in multiple R&D venues - big pharma, large biotech, start-up ventures, academia, and nonprofit research institutes - with a clear description of the degrees and training that will prepare students well for a career in this arena Analyzes the organization of pharmaceutical R&D, taking into account human resources considerations like recruitment and configuration, management of discovery and development processes, and the coordination of internal research within, and beyond, the organization, including outsourced work Presents a consistent, well-connected, and logical dialogue that readers will find both comprehensive and approachable Addresses new areas such as CRISPR gene editing technologies and RNA-based drugs and vaccines, personalized medicine and ethical and moral issues, AI/machine learning and other in silico approaches, as well as completely updating all chapters
Featuring contributions from respected theologians J.I. Packer, D.A. Carson, Colin Brown, Peter Toon, and many others, this thorough and practical survey of Christianity's basic beliefs and their meanings and applications for modern life also includes a user-friendly glossary and brief articles on the key shapers of Christian faith throughout history.
The decision to release someone from psychiatric hospital, forensic services or prison is often controversial, and forensic psychologists play a key role in assessing the risk of recidivism. In Violence Risk, Chris Webster and Steve Hucker discuss the accuracy of prediction and highlight how violence assessments would improve if well-established findings became entrenched in clinical and research practice. Although the authors write the majority of the text, specialist colleagues add essential material on subjects such as averting spousal assault, sex offending, and improving community support.
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