This book reflects Stephen Waxman's three decades of research on the form and functions of the brain and spinal cord. Building on his experience as a neuroscientist studying model systems as primitive as eels and as a neurologist studying humans, Waxman discusses a wide variety of topics, including the design principles that optimize neural function; molecular and cellular substrates of behavior; the role of glial cells in the brain; the molecular basis for pain; plasticity in the brain and spinal cord; strategies for promoting functional recovery in disorders such as multiple sclerosis, spinal cord injury, and stroke; and prospects for rebuilding the brain and spinal cord. The pieces provide example after example of the elegance of design of the nervous system, of the intricate interplay between structure and function in health and disease, and of the rich borderland between neuroscience and neurology.
Diseases of the Spine and Spinal Cord reviews the full spectrum of disorders affecting this region including primary spinal tumors and metastases, infection, degenerative diseases, and trauma. Presenting an inter-disciplinary perspective, the book includes up-to-date information on therapy [including neurosurgical], new information on developmental disorders of the spine, and a definitive chapter on trauma, including information on biomechanics. A separate chapter on pain syndromes also is included.
With more than 3500 high-quality drawings and photographs, this complete referenceprovides a solid foundation in basic science as well as step-by-step guidelines tohundreds of fixed prosthodontic procedures. Separate sections on planning andpreparation, clinical procedures, and laboratory procedures make it easier to look upthe information you need.• Illustrated procedures walk you through all the steps of treatment fromthe beginning to the final treatment result.• Summary charts provide a quick review of specific procedures such as ClassII inlay preparation and ceramic crown preparation, highlighting the indications,contraindications, advantages, disadvantages, preparation steps, recommendedarmamentarium, and criteria.• Prosthodontic Diagnostic Index helps you determine the appropriate treatmentsfor completely edentulous, partially edentulous, and dentate patients.
This book addresses the problem of articulatory speech synthesis based on computed vocal tract geometries and the basic physics of sound production in it. Unlike conventional methods based on analysis/synthesis using the well-known source filter model, which assumes the independence of the excitation and filter, we treat the entire vocal apparatus as one mechanical system that produces sound by means of fluid dynamics. The vocal apparatus is represented as a three-dimensional time-varying mechanism and the sound propagation inside it is due to the non-planar propagation of acoustic waves through a viscous, compressible fluid described by the Navier-Stokes equations. We propose a combined minimum energy and minimum jerk criterion to compute the dynamics of the vocal tract during articulation. Theoretical error bounds and experimental results show that this method obtains a close match to the phonetic target positions while avoiding abrupt changes in the articulatory trajectory. The vocal folds are set into aerodynamic oscillation by the flow of air from the lungs. The modulated air stream then excites the moving vocal tract. This method shows strong evidence for source-filter interaction. Based on our results, we propose that the articulatory speech production model has the potential to synthesize speech and provide a compact parameterization of the speech signal that can be useful in a wide variety of speech signal processing problems. Table of Contents: Introduction / Literature Review / Estimation of Dynamic Articulatory Parameters / Construction of Articulatory Model Based on MRI Data / Vocal Fold Excitation Models / Experimental Results of Articulatory Synthesis / Conclusion
An expert in pulmonary medicine shares a wide-ranging exploration of the human lung: the organ that explains our origins and holds the keys to our future. We take an average of 7.5 million breaths a year and some 600 million in our lifetime, and what goes on in our body each time oxygen is taken in and carbon dioxide expelled is nothing short of miraculous. “Our lungs are the lynchpin between our bodies and the outside world,” writes pulmonologist Michael Stephen. And yet, we too often take our lungs for granted. In Breath Taking, Stephen sheds much-needed light on our extraordinary lungs. He relates the history of oxygen on Earth and the evolutionary origins of breathing, and explores the healing power of breath and its spiritual potential. Stephen interweaves his narrative with scientific history, such as the development of the lung transplant, and poignant human stories, including his own frantic attempts to engage his son’s lungs at birth. Despite great advances in science, our lungs are ever more threatened. Asthma is on the rise, increasing anxiety leaves us vulnerable to disease, and COVID-19 has revealed that vulnerability in historic ways. Breath Taking offers inspiration and hope, inspiration, and vital perspective to us all.
The fourth edition of this internationally acclaimed, seminal textbook on the subject of clinical pediatric urology is completely updated. World-renowned experts in the field present state-of-the-art developments in all areas of clinical pediatric urology, from diagnosis to treatment and from theory to practice. Clinical Pediatric Urology is clinical in orientation and practical in presentation, covering every illness, diagnostic method and appropriate treatment in pediatric urology from the embryo onwards. Each chapter is lavishly illustrated with full color photographs and medical artwork. Tables, graphs and charts lend further support to the detailed and comprehensive text, all in a single, easily accessed volume. This is a useful and informative reference for students and specialists alike.
This book covers the normal anatomy of the human body as seen in the entire gamut of medical imaging. It does so by an initial traditional anatomical description of each organ or system followed by the radiological anatomy of that part of the body using all the relevant imaging modalities. The third edition addresses the anatomy of new imaging techniques including three-dimensional CT, cardiac CT, and CT and MR angiography as well as the anatomy of therapeutic interventional radiological techniques guided by fluoroscopy, ultrasound, CT and MR. The text has been completely revised and over 140 new images, including some in colour, have been added. A series of 'imaging pearls' have been included with most sections to emphasise clinically and radiologically important points. The book is primarily aimed at those training in radiology and preparing for the FRCR examinations, but will be of use to all radiologists and radiographers both in training and in practice, and to medical students, physicians and surgeons and all who use imaging as a vital part of patient care. The third edition brings the basics of radiological anatomy to a new generation of radiologists in an ever-changing world of imaging. This book covers the normal anatomy of the human body as seen in the entire gamut of medical imaging. It does so by an initial traditional anatomical description of each organ or system followed by the radiological anatomy of that part of the body using all the relevant imaging modalities. The third edition addresses the anatomy of new imaging techniques including three-dimensional CT, cardiac CT, and CT and MR angiography as well as the anatomy of therapeutic interventional radiological techniques guided by fluoroscopy, ultrasound, CT and MR. The text has been completely revised and over 140 new images, including some in colour, have been added. A series of 'imaging pearls' have been included with most sections to emphasise clinically and radiologically important points. The book is primarily aimed at those training in radiology, but will be of use to all radiologists and radiographers both in training and in practice, and to medical students, physicians and surgeons and all who use imaging as a vital part of patient care. The third edition brings the basics of radiological anatomy to a new generation of radiologists in an ever-changing world of imaging. - Anatomy of new radiological techniques and anatomy relevant to new staging or treatment regimens is emphasised. - 'Imaging Pearls' that emphasise clinically and radiologically important points have been added throughout. - The text has been revised to reflect advances in imaging since previous edition. - Over 100 additional images have been added.
This text is intended to reinforce the importance of a systematic patient assessment and management approach to paramedic students by presenting them with 20 case studies on the most important trauma emergencies they are likly to encounter in the field. emergencies
Now in its 7th edition, this popular, must-have text remains the only encyclopedic resource for veterinary internal medical problems. The internationally acclaimed "gold standard" offers unparalleled coverage of pathophysiology, diagnosis, and treatment of diseases affecting dogs and cats, as well as the latest information on the genome, clinical genomics, euthanasia, innocent heart murmurs, hyperbaric medicine, home prepared and raw diets, obesity, botulism, artificial pacing of the heart, cancer vaccines, and more. The 7th edition combines the convenience of a two-volume printed textbook with the enhanced functionality of an Expert Consult website that enables you to electronically search your entire book and study more efficiently. With instant access to the most reliable information available, you’ll always be at the forefront of veterinary care! Fully searchable online text provides fast, easy access to the most reliable information in the field. More than 150 clinical algorithms throughout the text aid in disease-identification and decision-making. Expanded online chapter content enhances your understanding through additional text, illustrations, tables, and boxes. Hyperlinked client information sheets streamline reference of specific conditions and enhance communication with clients. Extensive online reference list directs you to full-text PubMed abstracts for additional research. Thoroughly updated and expanded content, including 90 new chapters, addresses the latest developments across the full spectrum of small animal care. Companion Expert Consult website enhances your learning experience with the ability to search the entire electronic text instantly, make notes, and highlight content for easy review. Expert Consult also gives you instant access to: More than 150 procedural videos that guide you step-by-step through essential procedures. An interactive drug formulary that makes it easier to find and cross-reference key drug information. Audio files that help you identify heart abnormalities by their sound.
Apply the latest scientific and clinical advances with Wall & Melzack's Textbook of Pain, 6th Edition. Drs. Stephen McMahon, Martin Koltzenburg, Irene Tracey, and Dennis C. Turk, along with more than 125 other leading authorities, present all of the latest knowledge about the genetics, neurophysiology, psychology, and assessment of every type of pain syndrome. They also provide practical guidance on the full range of today's pharmacologic, interventional, electrostimulative, physiotherapeutic, and psychological management options. Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located. Benefit from the international, multidisciplinary knowledge and experience of a "who's who" of international authorities in pain medicine, neurology, neurosurgery, neuroscience, psychiatry, psychology, physical medicine and rehabilitation, palliative medicine, and other relevant fields. Translate scientific findings into clinical practice with updates on the genetics of pain, new pharmacologic and treatment information, and much more. Easily visualize important scientific concepts with a high-quality illustration program, now in full color throughout. Choose the safest and most effective management methods with expanded coverage of anesthetic techniques. Stay abreast of the latest global developments regarding opioid induced hyperalgesia, addiction and substance abuse, neuromodulation and pain management, identification of specific targets for molecular pain, and other hot topics.
The Comprehensive Treatment of the Aging Spine provides all the state-of-the-art coverage you need on both operative and non-operative treatments for different clinical pathologies of the aging spine. Dr James Yue and a team of talented, pioneering orthopedic surgeons and neurosurgeons cover hot topics like minimally invasive fusion, dynamic stabilization, state-of-the-art intraspinous and biologic devices, and more...in print and online. Search the full text and access a video library online at expertconsult.com. Master the very latest techniques and technologies through detailed step-by-step surgical instructions, tips, and pearls. Stay current on the state-of-the-art in intraspinous and biologic devices—such as Stent (Alphatec) and Optimesh Spineology; thoracic techniques—kyphoplasty, vertebroplasty, and spacers; and conservative treatment modalities—including injection therapies, acupuncture, and yoga. Make expert-guided decisions on techniques and device selection using the collective clinical experience of pioneering editors and contributors. Identify the advantages and disadvantages for the full range of available microsurgical and endoscopic techniques for management of cervical, thoracic, and lumbar spine pathology—minimally invasive fusion, reconstruction, decompression, and dynamic stabilization.
This Gold Standard in clinical child neurology presents the entire specialty in the most comprehensive, authoritative, and clearly written fashion. Its clinical focus, along with relevant science, throughout is directed at both the experienced clinician and the physician in training. New editor, Dr. Ferriero brings expertise in neonatal neurology to the Fourth Edition. New chapters: Pathophysiology of Hypoxic Ischemic Encephalopathy, Congenital Disorders of Glycosylation, Pediatric Neurotransmitter Diseases, Neurophysiology of Epilepsy, Genetics of Epilepsy, Pediatric Neurorehabilitation Medicine, Neuropsychopharmacology, Pain and Palliative Care Management, Ethical Issues in Child Neurology
Since 1975, Dr. Kenneth Swaiman's classic text has been the reference of choice for authoritative guidance in pediatric neurology, and the 6th Edition continues this tradition of excellence with thorough revisions that bring you fully up to date with all that's new in the field. Five new sections, 62 new chapters, 4 new editors, and a reconfigured format make this a comprehensive and clearly-written resource for the experienced clinician as well as the physician-in-training. - Nearly 3,000 line drawings, photographs, tables, and boxes highlight the text, clarify key concepts, and make it easy to find information quickly.
Netter's Pediatrics, edited by Drs. Todd Florin and Stephen Ludwig, is a rich visual aid with more than 500 images by Dr. Frank Netter and other artists working in his style that will help you diagnose and care for children with common clinical conditions. This is the first time that Netter's drawings of pediatric illness are brought together in a single volume. The superb, accurate artwork accompanies up-to-date text contributed by physicians at the prestigious Children's Hospital of Philadelphia. The book provides you with all the at-a-glance information you need for a quick overview of common issues from nutrition, allergy, infectious disease, and adolescent medicine, to cancer and heart disease. This user-friendly, clinical reference is also a great tool for patient and staff education. - Efficiently review key details for each condition with 500 detailed, crystal-clear images provided by Frank H. Netter and others working in the Netter tradition. - Apply dependable, concise, clinical advice from a team of physicians at Children's Hospital of Philadelphia, one of the top children's hospitals in the U.S. - Get answers at a glance during pediatric rotations when studying for exams or preparing for consultations.
The field of neurology is being transformed, from a therapeutically nihilistic discipline with few effective treatments, to a therapeutic specialty which offers new, effective treatments for disorders of the brain and spinal cord. This remarkable transformation has bridged neuroscience, molecular medicine, and clinical investigation, and represents a major triumph for biomedical research. This book, which contains chapters by more than 29 internationally recognized authorities who have made major contributions to neurotherapeutics, tells the stories of how new treatments for disabling disorders of the nervous system, such as stroke, multiple sclerosis, Parkinson's disease, and migraine, were developed, and explores evolving themes and technologies that offer hope for even more effective treatments and ultimately cures for currently untreatable disorders of the brain and spinal cord. The first part of this book reviews the development of new therapies in neurology, from their inception in terms of basic science to their introduction into the clinical world. It also explores evolving themes and new technologies. This book will be of interest to everyone – clinicians and basic scientists alike – interested in diseases of the brain and spinal cord, and in the quest for new treatments for these disorders.* Presents the evolution of the field of neurology into a therapeutic discipline * Discusses lessons learned from past successes and applications to ongoing work* Explores the future of this field
Pastor Payne Donovan was weary to the bone. He often wondered if he made any difference in people's lives or if his church had any impact on the world around him. In the midst of Payne's despair, George Carlson, head of a genetic laboratory called SarkiSystems, offers hope to revive and embolden Payne's ministry by a merging of faith and technology. Dazzled by George's charisma, Payne agrees to go to a meeting and soon finds himself deeply entangled in a plan to revive the faith of the world. But the more Payne invests in the plan, the more broken his family becomes. Pastor Donovan must let go of the hope that SarkiSystems offers in order to find healing for his family and true hope for the world.
Cable Any Kind of Audio or Video Installation Put complete performance specifications for analog and digital audio and video installations -- from professional recording studios to living room theatres -- in the palm of your hand! Audio/Video Cable Installer’s Pocket Guide packs over 200 illustrations that clarify all the methods, procedures, and tools you need to successfully tackle even the most complex installation job. Great for everyone from home enthusiasts to professional engineers and technicians, the convenient take-along size is as perfect for professionals working out in the field as it is for hobbyists tinkering in the basement. Author Stephen Lampen, an industry pro, anticipates and answers your every question on analog and digital audio, analog and digital video, including high definition video cabling; connectors; using Category 5, 5e, and 6 to carry audio and video; installation; and much more.
Listening combines broad coverage of acoustics, speech and music perception psychophysics, and auditory physiology with a coherent theoretical orientation in a lively and accessible introduction to the perception of music and speech events. Handel treats the production and perception of music and speech in parallel throughout the text, arguing that their production and perception follows identical principles; music and speech share the same formal properties, involve the same cognitive mechanisms, and cannot exist in separate "modules." The way that a sound is produced determines the physical properties of the acoustic wave. These properties in turn lead to the perception of the event. The initial chapters take up physical processes, including a section on characterization of sound and discussion of the way instruments and speech produce musical sound. Handel explains how the environment affects perceived sounds, including reflection, reverberation, diffraction, and the Doppler effect. Subsequent chapters take up psychological processes: partitioning smeared sounds into discrete events, identifying sound sources, the units and phrases of speech and music, and speech and music rhythms. The final chapter provides a detailed treatment of the physiology and neurophysiology of the auditory system. All of the author's explanations are coherent and clear, and this strategy includes discussing particular pieces of research in detail rather than covering many things superficially Handel analyzes causes as well as describing phenomena and sets out for the reader the difficulties inherent in the research methods he discusses. He defines the physical, musical, and psychological terms used, even the most basic ones, and covers all of the experimental methods and statistical procedures in the text. A Bradford Book.
This book is a cross-cultural reference volume of all attested numerical notation systems (graphic, non-phonetic systems for representing numbers), encompassing more than 100 such systems used over the past 5,500 years. Using a typology that defies progressive, unilinear evolutionary models of change, Stephen Chrisomalis identifies five basic types of numerical notation systems, using a cultural phylogenetic framework to show relationships between systems and to create a general theory of change in numerical systems. Numerical notation systems are primarily representational systems, not computational technologies. Cognitive factors that help explain how numerical systems change relate to general principles, such as conciseness or avoidance of ambiguity, which apply also to writing systems. The transformation and replacement of numerical notation systems relates to specific social, economic, and technological changes, such as the development of the printing press or the expansion of the global world-system.
This is a comprehensive and up-to-date presentation of the processes by which biological systems, most notably the nervous system, affect behaviour. A fantastic art program, an applauded accessible writing style and a host of pedagogical features make the text relevant to the lives of the students taking biological psychology.
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