You Can't Padlock an Idea examines the educational programs undertaken at the Highlander Folk School in Tennessee and looks specifically at how these programs functioned rhetorically to promote democratic social change. Founded in 1932 by educator Myles Horton, the Highlander Folk School sought to address the economic and political problems facing communities in Appalachian Tennessee and other southern states. To this end Horton and the school's staff involved themselves in the labor and civil rights disputes that emerged across the south over the next three decades. Drawing on the Highlander archives housed at the Wisconsin Historical Society, the Avery Research Center in South Carolina, and the Highlander Research and Education Center in Tennessee, Stephen A. Schneider reconstructs the pedagogical theories and rhetorical practices developed and employed at Highlander. He shows how the school focused on developing forms of collective rhetorical action, helped students frame social problems as spurs to direct action, and situated education as an agency for organizing and mobilizing communities. Schneider studies how Highlander's educational programs contributed to this broader goal of encouraging social action. Specifically he focuses on four of the school's more established programs: labor drama, labor journalism, citizenship education, and music. These programs not only taught social movement participants how to create plays, newspapers, citizenship schools, and songs, they also helped the participants frame the problems they faced as having solutions based in collective democratic action. Highlander's programs thereby functioned rhetorically, insofar as they provided students with the means to define and transform oppressive social and economic conditions. By providing students with the means to comprehend social problems and with the cultural agencies (theater, journalism, literacy, and music) to address these problems directly, Highlander provided an important model for understanding the relationships connecting education, rhetoric, and social change.
2014 BMA Medical Book Awards Highly Commended in Anaesthesia category! Apply the latest scientific and clinical advances with Wall & Melzack's Textbook of Pain, 6th Edition. Drs. Stephen McMahon, Martin Koltzenburg, Irene Tracey, and Dennis C. Turk, along with more than 125 other leading authorities, present all of the latest knowledge about the genetics, neurophysiology, psychology, and assessment of every type of pain syndrome. They also provide practical guidance on the full range of today's pharmacologic, interventional, electrostimulative, physiotherapeutic, and psychological management options. Benefit from the international, multidisciplinary knowledge and experience of a "who's who" of international authorities in pain medicine, neurology, neurosurgery, neuroscience, psychiatry, psychology, physical medicine and rehabilitation, palliative medicine, and other relevant fields. Access the complete contents online anytime, anywhere at www.expertconsult.com. Translate scientific findings into clinical practice with updates on the genetics of pain, new pharmacologic and treatment information, and much more. Easily visualize important scientific concepts with a high-quality illustration program, now in full color throughout. Choose the safest and most effective management methods with expanded coverage of anesthetic techniques. Stay abreast of the latest global developments regarding opioid induced hyperalgesia, addiction and substance abuse, neuromodulation and pain management, identification of specific targets for molecular pain, and other hot topics.
Clinicians recognize that monitoring psychotropic levels provides invaluable information to optimize therapy and track treatment adherence, but they lack formal training specifically focused on the use of plasma antipsychotic levels for these purposes. As new technologies emerge to rapidly provide these results, the opportunity to integrate this information into clinical care will grow. This practical handbook clarifies confusing concepts in the literature on use of antipsychotic levels, providing clear explanations for the logic underlying clinically relevant concepts such as the therapeutic threshold and the point of futility, and how these apply to individual antipsychotics. It offers accessible information on the expected correlation between dosages and trough levels, and also provides a clear explanation of how to use antipsychotic levels for monitoring oral antipsychotic adherence, and methods to help clinicians differentiate between poor adherence and variations in drug metabolism. An essential resource for psychiatrists, psychiatric nurse practitioners, and mental health professionals worldwide.
This book provides a detailed view of the molecular structures of DNA and RNA and how they are recognised by small molecules and proteins. Extensive source material is provided, including information on relevant web sites and computer programmes. The major methods of structural investigation for nucleic acids: X-ray crystallography, NMR, and molecular modelling are reviewed and their scope and limitations (in the context of nucleic acids) discussed. Also covered are the conformational features of nucleic acid building blocks, including a description of how base-pair morphologies are analysed; the structures of DNA double helices and helical oligonucleotides, emphasising current ideas on sequence-dependent structure; and DNA-DNA interactions, including triplexes and quadruplexes. The principles of RNA folding, ribosome, and ribozyme structure are also surveyed. Both covalent and non-covalent nucleic acid interactions with small molecules are described, with the emphasis on recognition principles and sequence specific gene recognition. The principles of protein - nucleic acid are covered, focussing on regulatory proteins. Nucleic Acid Structure and Recognition will therefore equip readers with a good understanding of all the important aspects of this major field. The Nucleic Acid Database (NDB) crystallographic and NMR structures for the nucleic acid structures described in the book are freely available through the Nucleic Acid Structure and Recognition website.
Between 1790 and 1850, waves of Anglo-Americans, African Americans, and European immigrants flooded the Old Northwest (modern-day Ohio, Indiana, Michigan, Illinois, and Wisconsin). They brought with them a mosaic of Christian religious belief. Stephen T. Kissel draws on a wealth of primary sources to examine the foundational role that organized religion played in shaping the social, cultural, and civic infrastructure of the region. As he shows, believers from both traditional denominations and religious utopian societies found fertile ground for religious unity and fervor. Able to influence settlement from the earliest days, organized religion integrated faith into local townscapes and civic identity while facilitating many of the Old Northwest's earliest advances in literacy, charitable public outreach, formal education, and social reform. Kissel also unearths fascinating stories of how faith influenced the bonds, networks, and relationships that allowed isolated western settlements to grow and evolve a distinct regional identity. Perceptive and broad in scope, America’s Religious Crossroads illuminates the integral relationship between communal and spiritual growth in early Midwestern history.
The successful structure of the previous edition of Principles of Fermentation Technology has been retained in this third edition, which covers the key component parts of a fermentation process including growth kinetics, strain isolation and improvement, inocula development, fermentation media, fermenter design and operation, product recovery, and the environmental impact of processes. This accurate and accessible third edition recognizes the increased importance of animal cell culture, the impact of the post-genomics era on applied science and the huge contribution that heterologous protein production now makes to the success of the pharmaceutical industry. This title is ideally suited for both newcomers to the industry and established workers as it provides essential and fundamental information on fermentation in a methodical, logical fashion. Stanbury, Whitaker and Hall have integrated the biological and engineering aspects of fermentation to make the content accessible to members of both disciplines with a focus on the practical application of theory. This text collates all the fermentation fundamentals into one concise reference, making it a valuable resource for fermentation scientists, as well as those studying in the field. - Retains its successful structure and covers all components of the fermentation process - Integrates the biological and engineering aspects of fermentation to discuss the most recent developments and advancements in the field - Written in a style accessible to readers from either a biological or engineering background with each chapter supported by an extensive bibliography
Since 1975, Dr. Kenneth Swaiman's classic text has been the reference of choice for authoritative guidance in pediatric neurology, and the 6th Edition continues this tradition of excellence with thorough revisions that bring you fully up to date with all that's new in the field. Five new sections, 62 new chapters, 4 new editors, and a reconfigured format make this a comprehensive and clearly-written resource for the experienced clinician as well as the physician-in-training. - Nearly 3,000 line drawings, photographs, tables, and boxes highlight the text, clarify key concepts, and make it easy to find information quickly.
Seeking a broad reexamination of visual culture through the lenses of ecocriticism, environmental justice, and animal studies, this compendium offers a diverse range of art-historical criticism formulated within an ecological context. Picture Ecology brings together scholars whose contributions extend chronologically and geographically from 11th-century Chinese painting to contemporary photography of California wildfires. The book's 17 interdisciplinary essays provide a dynamic, cross-cultural approach to an increasingly vital area of study, emphasizing the environmental dimensions inherent in the content and materials of aesthetic objects. Picture Ecology provides valuable new approaches for considering works of art, in ways that are timely, intellectually stimulating, and universally significant.
This softcover manual covers all procedures and techniques necessary for certification in critical care from the internal medicine, anesthesiology, and surgical critical care certification exam. Each procedure or monitoring technique discusses indications/contraindications, equipment, anatomy, techniques, postprocedure care, and complications. Specific nursing indications are indicated where appropriate.
A comprehensive review of toxicology for the small animal practitioner! Guest editors Safdar Khan and Stephen Hooser present articles on trends of animal poisoning cases in the USA, use of lipid emulsions, epidemiology of mushroom poisoning cases, toxicology of ADHD drugs, toxicology of human NSAIDS, diagnostic toxicology with emphasis on how to investigate or what to do in food-related outbreaks, toxicology of avermectins (ivermectins, moxidectin, doramectin, selamectin), rodenticides toxicosis, include difethiolone, toxicology of newer pesticides, toxicology of explosives, recently recognized nephrotoxic agents/toxicants, calcium channel blocker toxicosis, adverse effects, and more!
This book presents a practical framework for the application of big data, cloud, and pervasive and complex systems to sustainable solutions for urban environmental challenges. It covers the technologies, potential, and possible and impact of big data on energy efficiency and the urban environment. The book first introduces key aspects of big data, cloud services, pervasive computing, and mobile technologies from a pragmatic design perspective, including sample open source firmware. Cloud services, mobile and embedded platforms, interfaces, operating system design methods, networking, and middleware are all considered. The authors then explore in detail the framework, design principles, architecture and key components of developing energy systems to support sustainable urban environments. The included case study provides a pathway to improve the eco-efficiency of urban transport, demonstrating how to design an energy efficient next generation urban navigation system by leveraging vast cloud data sets on user-behavior. Ultimately, this resource maps big data’s pivotal intersection with rapid global urbanization along the path to a sustainable future.
This book examines the role of neurons in multiple sclerosis (MS) and the changes that occur in neurons as a result of MS. It places MS in a new and important perspective that not only explains the basis for symptom production, remission, and progress in MS, but also promises to open up new therapeutic possibilities.* Brings together the latest information from clinical, pathological, imaging, molecular, and pharmacological realms to explore the neurobiology of Multiple Sclerosis* Places MS in a new and important perspective that promises to open up new therapeutic avenues* Superbly illustrated and referenced
A practical, user-friendly book providing clear strategies to help psychiatric practitioners reason through therapeutic and management options, construct back-up plans, incorporate shared decision-making, and devise personalized treatment algorithms using all therapeutic modalities. Featuring summary tables and illustrative case vignettes.
Despite the lack of guidance available for practitioners, extensive polypharmacy has become the primary method of treating patients with severe and chronic mood, anxiety, psychotic or behavioral disorders. This ground-breaking new book provides an overview of psychopharmacology knowledge and decision-making strategies, integrating findings from evidence-based trials with real-world clinical presentations. It adopts the approach and mind-set of a clinical investigator and reveals how prescribers can practice 'bespoke psychopharmacology', tailoring care to the individualized needs of patients. Practitioners at all levels of expertise will enhance their ability to devise rationale-based treatments, targeting manifestations of dysfunctional neural circuitry and dimensions of psychopathology that cut across conventional psychiatric diagnoses. Presented in a user-friendly, practical, full-colour layout and incorporating summary tables, bullet points, and illustrative case vignettes, it is an invaluable guide for all healthcare professionals prescribing psychotropic medications, including psychiatry specialists, primary care physicians, and advanced practice registered nurses.
Contains numerous color illustrations of the characteristic clinical and histological manifestations of viral ailments to aid in quick diagnosis and treatment. Mucocutaneous Manifestations of Viral Diseases outlines a brief taxonomy and history of each disease a timeline of infection and progression clinical
Clinical Respiratory Medicine provides practical guidance to help you more effectively diagnose and manage the full range of pulmonary disorders, including those seen in today's most challenging patient populations. In print and online, this medical reference book delivers the answers you need to ensure the best outcomes. - Better manage and treat patients with pulmonary disease with complete clinical coverage of the critical information relevant to your everyday practice, presented in a templated, user-friendly format. - Find critical information quickly with the help of diagnostic algorithms. - Test your knowledge of respiratory medicine with the help of 400 brand-new review questions. - Watch and learn. Over 25 videos of practical procedures are available online at www.expertconsult.com. - Thoroughly understand the needs and recognize co-morbidities of particular patient populations through entirely new chapters on lung structure, echocardiography, and obesity and its effects. - Access the latest research and advancements in lung cancer, benign tumors, and the importance of pulmonary physiology in understanding lung function and the disease processes that occur.
Lichens are a unique form of plant life, the product of a symbiotic association between an alga and a fungus. The beauty and importance of lichens have long been overlooked, despite their abundance and diversity in most parts of North America and elsewhere in the world. This stunning book--the first accessible and authoritative guidebook to lichens of the North American continent--fills the gap, presenting superb color photographs, descriptions, distribution maps, and keys for identifying the most common, conspicuous, or ecologically significant species. The book focuses on 805 foliose, fruticose, and crustose lichens (the latter rarely included in popular guidebooks) and presents information on another 700 species in the keys or notes; special attention is given to species endemic to North America. A comprehensive introduction discusses the biology, structure, uses, and ecological significance of lichens and is illustrated with 90 additional color photos and many line drawings. English names are provided for most species, and the book also includes a glossary that explains technical terms. This visually rich and informative book will open the eyes of nature lovers everywhere to the fascinating world of lichens.
Mason's World Encyclopedia of Livestock Breeds and Breeding describes breeds of livestock worldwide as well as a range of breed-related subjects such as husbandry, health and behaviour. This definitive and prestigious reference work presents easily accessible information on domestication (including wild ancestors and related species), genetics and breeding, livestock produce and markets, as well as breed conservation and the cultural and social aspects of livestock farming. Written by renowned livestock authorities, these volumes draw on the authors' lifelong interest and involvement in livestock breeds of the world, presenting a unique, comprehensive and fully cross-referenced guide to cattle, buffalo, horses, pigs, sheep, asses, goats, camelids, yak and other domesticants.
Beatrix von Falklenburg, the childless wife of an impoverished and, it must be said, neglectful, Count, was living the life of a Prague socialite when a murder involving her elderly uncle pulled her into the orbit of Edward VII of England and the German Kaiser. And into that of a Prague police inspector, as well as into a deeper interaction with her unflappable butler, Müller, and her lady's maid, Sabine. All of which is recounted in The Countess of Prague. Her role in that 1904 investigation has brought her to the attention of the Hapsburg Emperor Franz Josef I, who has her summoned to his palace in Vienna. There he tasks her with probing the "murder/suicide" in 1889 at Crown Prince Rudolf's hunting lodge at Mayerling and looking for possible papers that might contain revealing information or evidence of what happened there. Did Rudolf murder Baroness Marie Vetsera and shoot himself? And might there remain something that would reveal "the dreaded secret" that could topple the Hapsburg dynasty, as rumor had long hinted? Something that has survived to 1905? But before Trixie is handed her assignment, a terrible murder occurs on a snowy Prague funicular railway. Inspector Schneider pulls her away from a night at the opera to the crime scene. The only clue to the identity of the decapitated corpse is a tiny slip of paper in his waistcoat pocket - a piece of paper with Trixie's telephone number on it. Thus she becomes involved in what proves to be the murder of the Great Orsini, Master Illusionist, and in what follows. It's an investigation she cannot drop, despite her mission for her Emperor.
Managing the Drug Discovery Process, Second Edition thoroughly examines the current state of pharmaceutical research and development by providing experienced perspectives on biomedical research, drug hunting and innovation, including the requisite educational paths that enable students to chart a career path in this field. The book also considers the interplay of stakeholders, consumers, and drug firms with respect to a myriad of factors. Since drug research can be a high-risk, high-payoff industry, it is important to students and researchers to understand how to effectively and strategically manage both their careers and the drug discovery process. This new edition takes a closer look at the challenges and opportunities for new medicines and examines not only the current research milieu that will deliver novel therapies, but also how the latest discoveries can be deployed to ensure a robust healthcare and pharmacoeconomic future. All chapters have been revised and expanded with new discussions on remarkable advances including CRISPR and the latest gene therapies, RNA-based technologies being deployed as vaccines as well as therapeutics, checkpoint inhibitors and CAR-T approaches that cure cancer, diagnostics and medical devices, entrepreneurship, and AI. Written in an engaging manner and including memorable insights, this book is aimed at anyone interested in helping to save countless more lives through science. A valuable and compelling resource, this is a must-read for all students, educators, practitioners, and researchers at large—indeed, anyone who touches this critical sphere of global impact—in and around academia and the biotechnology/pharmaceutical industry. - Considers drug discovery in multiple R&D venues - big pharma, large biotech, start-up ventures, academia, and nonprofit research institutes - with a clear description of the degrees and training that will prepare students well for a career in this arena - Analyzes the organization of pharmaceutical R&D, taking into account human resources considerations like recruitment and configuration, management of discovery and development processes, and the coordination of internal research within, and beyond, the organization, including outsourced work - Presents a consistent, well-connected, and logical dialogue that readers will find both comprehensive and approachable - Addresses new areas such as CRISPR gene editing technologies and RNA-based drugs and vaccines, personalized medicine and ethical and moral issues, AI/machine learning and other in silico approaches, as well as completely updating all chapters
The apocalypse is a motif that lies behind many religious beliefs and practices. 'War in Heaven/Heaven on Earth' theorizes the apocalyptic as it has arisen in a variety of religious traditions, from Native American religion to Islam in Northern Nigeria and new terrorist movements. Millennial theory and history are explored from the perspective of social psychology, sociology and post-modern philosophy. The volume is unique in applying an analysis of millennial themes to a comparative study of religion.
This unique and practical resource provides the most complete and concise summary of underlying principles and approaches to studying nucleic acid structure, including discussion of x-ray crystallography, NMR, molecular modelling, and databases. Its focus is on a survey of structures especially important for biomedical research and pharmacological applications. To aid novices, Principles of Nucleic Acid Structure includes an introduction to technical lingo used to describe nucleic acid structure and conformations (roll, slide, twist, buckle, etc.). This completely updated edition features expanded coverage of the latest advances relevant to recognition of DNA and RNA by small molecules and proteins. In particular, the reader will find extensive new discussions on: RNA folding, ribosome structure and antibiotic interactions, DNA quadruplexes, DNA and RNA protein complexes, and short interfering RNA (siRNA). This handy guide ends with a complete list of resources, including relevant online databases and software. - Completely updated with expanded discussion of topics such as RNA folding, ribosome structure and antibiotic interactions, DNA quadruplexes, DNA and RNA protein complexes, and short interfering RNA (siRNA) - Includes a complete list of resources, including relevant online databases and software - Defines technical lingo for novices
Your days spent fruitlessly scouring textbooks and websites for credible vet information are over! Now you can get the whole story — the accurate story — all in one place. Introducing The Textbook of Veterinary Internal Medicine, Expert Consult, 8th Edition. Still the only comprehensive resource for veterinary internal medical problems, this faculty-and-student-favorite offers unparalleled coverage of pathophysiology, diagnosis, and disease treatments for dogs and cats. In addition to new chapters and discussions on the industry’s most topical issues, this "gold standard in vet medicine" comes with hundreds of original videos, algorithms, and learning tools to really bring all the information to life. There’s no better source to help you unlock the secrets of veterinary medicine than Ettinger’s! Fully searchable online text offers quick access to the most trusted information in the field. Complete library of over 500 original clinical videos you can believe in. Instead of fruitless YouTube searches, each video expertly breaks down veterinary procedures and important signs of diseases and disorders that are difficult or impossible to understand from written descriptions alone. In-depth coverage of timely issues includes expert explanations on topics such as the genome, clinical genomics, euthanasia, innocent heart murmurs, hyperbaric medicine, home prepared and raw diets, obesity, botulism, artificial pacing of the heart, and cancer vaccines. Thousands of references accessible from the printed book with the click of a QR code. 256 all-new client information sheets can be downloaded, customized, and printed as client handouts. 214 new and updated clinical algorithms aid in disease identification and decision-making. Exclusive access to Expert Consult Online website offers the complete library of original video clips, heart sounds, the full collection of client information sheets, and hyperlinking of references to their source abstracts in PubMed. NEW! In-depth coverage of the latest information and trends in small animal internal medicine. Completely new section on minimally-invasive interventional procedures includes techniques for treating respiratory, cardiovascular, gastrointestinal, urologic/nephrologic, and neoplastic disorders. 17 new chapters address the major clinicopathologic abnormalities that occur in canine and feline laboratory testing. Completely new section on management of mutually-antagonistic comorbidities spotlights concurrent cardiac and renal disease, concurrent infection in patients requiring immunosuppression, and concurrent diabetes mellitus and corticosteroid-dependent disease. Expert explanations on topics such as evidence-based medicine, distinguishing behavioral disorders from medical neurologic disorders, blood transfusion techniques, hyperadrenocorticism (Cushing’s disease), chronic kidney disease, respiratory and inhalant therapy, and many more.
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