For more than 40 years, dozens of film directors, writers and producers tried and failed to adapt John Kennedy Toole's Pulitzer Prize-winning novel A Confederacy of Dunces. Along the way lawsuits were filed, filming locations destroyed, friendships shattered, reputations trashed, production companies bankrupted. Drawing on exclusive interviews, internal documents and private correspondence, this book tells the remarkable story of the non-making of A Confederacy of Dunces as a breathless and absurdist thriller. Celebrity appearances include John Belushi, Steven Soderbergh, Stephen Fry, Robin Williams, Warren Beatty and Harvey Weinstein, among others.
This book is an outgrowth of a collection of 100 problems chosen to celebrate the 100th anniversary of the undergraduate math honor society Pi Mu Epsilon. Each chapter describes a problem or event, the progress made, and connections to entries from other years or other parts of mathematics. In places, some knowledge of analysis or algebra, number theory or probability will be helpful. Put together, these problems will be appealing and accessible to energetic and enthusiastic math majors and aficionados of all stripes. Stephan Ramon Garcia is WM Keck Distinguished Service Professor and professor of mathematics at Pomona College. He is the author of four books and over eighty research articles in operator theory, complex analysis, matrix analysis, number theory, discrete geometry, and other fields. He has coauthored dozens of articles with students, including one that appeared in The Best Writing on Mathematics: 2015. He is on the editorial boards of Notices of the AMS, Proceedings of the AMS, American Mathematical Monthly, Involve, and Annals of Functional Analysis. He received four NSF research grants as principal investigator and five teaching awards from three different institutions. He is a fellow of the American Mathematical Society and was the inaugural recipient of the Society's Dolciani Prize for Excellence in Research. Steven J. Miller is professor of mathematics at Williams College and a visiting assistant professor at Carnegie Mellon University. He has published five books and over one hundred research papers, most with students, in accounting, computer science, economics, geophysics, marketing, mathematics, operations research, physics, sabermetrics, and statistics. He has served on numerous editorial boards, including the Journal of Number Theory, Notices of the AMS, and the Pi Mu Epsilon Journal. He is active in enrichment and supplemental curricular initiatives for elementary and secondary mathematics, from the Teachers as Scholars Program and VCTAL (Value of Computational Thinking Across Grade Levels), to numerous math camps (the Eureka Program, HCSSiM, the Mathematics League International Summer Program, PROMYS, and the Ross Program). He is a fellow of the American Mathematical Society, an at-large senator for Phi Beta Kappa, and a member of the Mount Greylock Regional School Committee, where he sees firsthand the challenges of applying mathematics.
North American Wildland Plants contains descriptions of the salient characteristics of the most important wildland plants of North America. This comprehensive reference assists individuals with limited botanical knowledge as well as natural resource professionals in identifying wildland plants. The two hundred species of wildland plants in this book were selected because of their abundance, desirability, or poisonous properties. Each illustration has been enhanced with labels pointing to key characteristics to facilitate the identification of unknown plants. Each plant description includes plant characteristics, an illustration of the plant with enlarged parts, and a general distribution map for North America. Each species description includes nomenclature; life span; origin; season of growth; inflorescence, flower or spikelet, or other reproductive parts; vegetative parts; and growth characteristics. Brief notes are included on habitat; livestock losses; and historic, food, and medicinal uses. This third edition contains additional refinements in the nomenclature, distribution, illustrations, and descriptions of plants.
A vast swath of prairie situated between the Missouri River and the Rocky Mountains, the North American Great Plains extend across ten states in the United States and three provinces in Canada. The dominant vegetation is grass—both the native species that have long thrived here and the cultivated crops such as corn, wheat, and sorghum that are the result of human agricultural activity. This comprehensive guide, written by three grass specialists, is an invaluable tool for identification of the approximately 450 species of grasses that occur on the Great Plains. In each description, the authors cover distribution, habitat, forage value, and toxicity and include a detailed black-and-white illustration of the grass as well as a range map. Intended as a reference for landowners, rangeland specialists, students, state and federal agency professionals, and nongovernment conservation organizations, Grasses of the Great Plains will serve a wide audience of users involved in and dedicated to grassland management.
There are only few discoveries and new technologies in physical sciences that have the potential to dramatically alter and revolutionize our electronic world. Topological insulators are one of them. The present book for the first time provides a full overview and in-depth knowledge about this hot topic in materials science and condensed matter physics. Techniques such as angle-resolved photoemission spectrometry (ARPES), advanced solid-state Nuclear Magnetic Resonance (NMR) or scanning-tunnel microscopy (STM) together with key principles of topological insulators such as spin-locked electronic states, the Dirac point, quantum Hall effects and Majorana fermions are illuminated in individual chapters and are described in a clear and logical form. Written by an international team of experts, many of them directly involved in the very first discovery of topological insulators, the book provides the readers with the knowledge they need to understand the electronic behavior of these unique materials. Being more than a reference work, this book is essential for newcomers and advanced researchers working in the field of topological insulators.
Foreign direct investment (FDI) assumed a prominent role in Central East Europe (CEE) early on in the transition process. Foreign investors were assigned the task of restructuring markets, providing capital and knowledge for investment in technologically outdated and financially ailing firms.
Combining economic, social-psychological and sociological approaches to trust, this book provides a general theoretical framework to causally explain conditional and unconditional trust; it also presents an experimental test of the corresponding integrative model and its predictions. Broadly, it aims at advancing a cognitive turn in trust research by highlighting the importance of (1) an actor ́s context-dependent definition of the situation and (2) the flexible and dynamic degree of rationality involved. In essence, trust is as “multi-faceted” as there are cognitive routes that take us to the choice of a trusting act. Therefore, variable rationality has to be incorporated as an orthogonal dimension to the typological space of trust. The theory presents an analytically tractable model; the empirical test combines trust games, high- and low-incentive conditions, framing manipulations, and psychometric measurements, and is complemented by decision-time analyses.
The author develops the effective-mass theory of excitons in low-dimensional semiconductors and describes numerical methods for calculating the optical absorption including Coulomb interaction, geometry, and external fields. The theory is applied to Fano resonances in low-dimensional semiconductors and the Zener breakdown in superlattices. Comparing theoretical results with experiments, the book is essentially self-contained; it is a hands-on approach with detailed derivations, worked examples, illustrative figures, and computer programs. The book is clearly structured and will be valuable as an advanced-level self-study or course book for graduate students, lecturers, and researchers.
The Oxford Handbook for the Foundation Programme returns for a new edition with clear and thorough clinical guidance and honest advice to help you excel in your first two years as a doctor. This edition has been fully updated in line with the latest guidelines and gives you practical, step-by-step guidance on everything from neurological to gastroenterlogical presentations. Emergency presentations are easily identifiable, giving you fast access to the information you need. This edition also includes a fully revised chapter on pharmacopeia with references to the British National Formulary, as well as chapters on practical procedures and interpreting results, acting as a guide for surviving on - and off - the wards. The Oxford Handbook for the Foundation Programme is also a unique resource for things they don't teach you at medical school about being a doctor and life on the wards. The authors have drawn on their own experiences and careful research to help you understand issues ranging from your pay and pension, stress and workplace relations, paperwork, and career development. This is an excellent resource for Foundation Programme trainees and medical students preparing themselves for life as a doctor. With this pocket-sized guide at your side you'll never be alone on the wards again.
This volume addresses the question of what it is like to be depressed. Despite the vast amount of research that has been conducted into the causes and treatment of depression, the experience of depression remains poorly understood. Indeed, many depression memoirs state that the experience is impossible for others to understand. However, it is at least clear that changes in emotion, mood, and bodily feeling are central to all forms of depression, and these are the book's principal focus. In recent years, there has been a great deal of valuable philosophical and interdisciplinary research on the emotions, complemented by new developments in philosophy of psychiatry and scientifically-informed phenomenology. The book draws on all these areas, in order to offer a range of novel insights into the nature of depression experiences. To do so, it brings together a distinguished group of philosophers, psychiatrists, anthropologists, clinical psychologists and neuroscientists, all of whom have made important contributions to current research on emotion and/or psychiatric illness.
This text provides discussion of the principle of freedom of establishment and focuses on the key issue of determining where a corporation has its 'seat' for legal purposes.
The experimental method is one commonly applied to issues of environmental economics; this book brings together 63 leading researchers in the area and their latest work exploring the behavioural underpinnings of experimental environmental economics. The essays in this volume will be illuminating for both researchers and practitioners, specific
This book examines the dynamic evolution of Western détente policies which sought to transform Europe and overcome its Cold War division through more communication and engagement. Kieninger challenges the traditional Cold War narrative that détente prolonged the division of Europe and precipitated America’s decline in the aftermath of the Vietnam War. Rather, he argues that policymakers in the U.S. Department of State and in Western Europe envisaged the stability enabled by détente as a precondition for change, as Communist regimes saw a sense of security as a prerequisite for opening up their societies to Western influence over time. Kieninger identifies the Helsinki Accords, Lyndon Johnson’s bridge building, and Willy Brandt’s Ostpolitik as efforts aimed at constructive changes in Eastern Europe through a multiplication of contacts, communication, and cooperation on all societal levels. This study also illuminates the longevity of America’s policy of peaceful change against the background of the nuclear stalemate and the military status quo.
This is a monograph written for the young and advanced researcher who is entering the field of wet granular matter, keen to understand the basic physical principles governing this state of soft matter. It treats wet granulates as a ternary system consisting of the grains, a primary, and a secondary fluid. After generally addressing wetting phenomena and outlining the basic facts on dry granular systems, a chapter on basic mechanisms and their effects is dedicated to every region of the ternary phase diagram. Effects of grain shape and roughness are considered as well. Rather than addressing engineering aspects like existing books on this topic do, this book aims to provide a generalized framework suitable for those who want to understand these systems on a more fundamental basis. It spans a wide scope of questions, ranging from possible general principles behind the emergence of structure and pattern, to the interpretation of geological outcrop features we encounter in nature.
This book provides the first comprehensive analysis of the immediate and likely longer-term consequences of Brexit for the UK’s competition law regime and includes the competition and subsidy control provisions of the EU-UK Trade and Cooperation Agreement. It has been written to be of value to scholars and practitioners of competition law, whilst also providing a useful guide to readers with only limited understanding of competition rules. The book provides a detailed critical discussion of how Brexit impacts on five key aspects of competition policy in the UK: legislation, institutions and cooperation; antitrust rules that prohibit anti-competitive agreements and the abuse of a dominant position; private enforcement, in particular actions for damages; regulation of mergers and acquisitions; and State aid or subsidy control rules.
North American Wildland Plants is the sixth edition of North American Range Plants. This comprehensive reference contains the salient characteristics of the most important wildland plants of North America and will help individuals with limited botanical knowledge as well as natural resource professionals to identify wildland plants. The two hundred species of wildland plants in this book were selected because of their abundance, desirability, or poisonous properties. ø Each of the illustrations has been enhanced to maximize the use of this book as a field guide. Each plant description includes characteristics for identification, an illustration of the plant with enlarged parts, and a general distribution map for North America. Each species description includes nomenclature; life span; origin; season of growth; inflorescence, flower or spikelet, or other reproductive parts; vegetative parts; and growth characteristics. Brief notes are included on habitat; livestock losses; and historic, food, and medicinal uses.
North American Range Plants has established itself as an essential source in the identification of important range plants. The two hundred plants described were selected on the basis of their abundance, desirability, or poisonous properties. These plants comprise the Master Plant List for the International Range Plant Identification contest, sponsored by the Society for Range Management. Each plant description includes characteristics for identification, an illustration of the plant with enlarged plant parts, and a general distribution map for North America. Each species description includes nomenclature, life span, origin, season of growth, inflorescence, flower or other reproductive parts, vegetative parts, and habitat.
Following their occupation by the Third Reich, Warsaw and Minsk became home to tens of thousands of Germans. In this exhaustive study, Stephan Lehnstaedt provides a nuanced, eye-opening portrait of the lives of these men and women, who constituted a surprisingly diverse population—including everyone from SS officers to civil servants, as well as ethnically German city residents—united in its self-conception as a “master race.” Even as they acclimated to the daily routines and tedium of life in the East, many Germans engaged in acts of shocking brutality against Poles, Belarusians, and Jews, while social conditions became increasingly conducive to systematic mass murder.
Neuroleptic malignant syndrome (NMS) and other hyperthermic conditions are rare complications of antipsychotic drugs that can cause discomfort, disability, and even death. As a result, every psychiatrist, physician, and mental health care professional needs to understand and identify these disorders in time to prevent a fatal outcome. Neuroleptic Malignant Syndrome and Related Conditions is an important tool for clinicians, outlining a framework for understanding, diagnosing, treating, and preventing these little-understood disorders. This new edition extensively updates and revises the first edition, integrating an explosion of findings that have occurred since the earlier edition was published in 1989. In addition to NMS, chapters focus on antipsychotic drug-related heatstroke, hyperthermia associated with other neuropsychiatric drugs, and malignant catatonia, as well as A new chapter on serotonin syndrome, the first comprehensive review to appear in the world literature. With the proliferation of serotonergic drugs such as Selective Serotonin Reuptake Inhibitors (SSRIs), the incidence of adverse reactions is on the rise, and this information will help practitioners spot early warning signals. Important information on thermoregulatory mechanisms to help clinicians understand the pathogenesis of hyperthermic conditions. With an understanding of the basic mechanisms underlying these conditions, practitioners will develop more effective strategies for recognition, diagnosis, and treatment. Written by four internationally renowned authorities on NMS, Neuroleptic Malignant Syndrome and Related Conditions is the most comprehensive resource on the subject in existence. With nearly 850 citations in the reference section, it is a must for researchers -- and for practitioners who need a practical approach based on the most current science.
This book provides an overview of automatic test pattern generation (ATPG) and introduces novel techniques to complement classical ATPG, based on Boolean Satisfiability (SAT). A fast and highly fault efficient SAT-based ATPG framework is presented which is also able to generate high-quality delay tests such as robust path delay tests, as well as tests with long propagation paths to detect small delay defects. The aim of the techniques and methodologies presented in this book is to improve SAT-based ATPG, in order to make it applicable in industrial practice. Readers will learn to improve the performance and robustness of the overall test generation process, so that the ATPG algorithm reliably will generate test patterns for most targeted faults in acceptable run time to meet the high fault coverage demands of industry. The techniques and improvements presented in this book provide the following advantages: Provides a comprehensive introduction to test generation and Boolean Satisfiability (SAT); Describes a highly fault efficient SAT-based ATPG framework; Introduces circuit-oriented SAT solving techniques, which make use of structural information and are able to accelerate the search process significantly; Provides SAT formulations for the prevalent delay faults models, in addition to the classical stuck-at fault model; Includes an industrial perspective on the state-of-the-art in the testing, along with SAT; two topics typically distinguished from each other.
This book presents an integrated framework for developing and testing computational models in psychology and related disciplines. Researchers and students are given the knowledge and tools to interpret models published in their area, as well as to develop, fit, and test their own models.
In the 1980s, traditional Business Intelligence (BI) systems focused on the delivery of reports that describe the state of business activities in the past, such as for questions like "How did our sales perform during the last quarter?" A decade later, there was a shift to more interactive content that presented how the business was performing at the present time, answering questions like "How are we doing right now?" Today the focus of BI users are looking into the future. "Given what I did before and how I am currently doing this quarter, how will I do next quarter?" Furthermore, fuelled by the demands of Big Data, BI systems are going through a time of incredible change. Predictive analytics, high volume data, unstructured data, social data, mobile, consumable analytics, and data visualization are all examples of demands and capabilities that have become critical within just the past few years, and are growing at an unprecedented pace. This book introduces research problems and solutions on various aspects central to next-generation BI systems. It begins with a chapter on an industry perspective on how BI has evolved, and discusses how game-changing trends have drastically reshaped the landscape of BI. One of the game changers is the shift toward the consumerization of BI tools. As a result, for BI tools to be successfully used by business users (rather than IT departments), the tools need a business model, rather than a data model. One chapter of the book surveys four different types of business modeling. However, even with the existence of a business model for users to express queries, the data that can meet the needs are still captured within a data model. The next chapter on vivification addresses the problem of closing the gap, which is often significant, between the business and the data models. Moreover, Big Data forces BI systems to integrate and consolidate multiple, and often wildly different, data sources. One chapter gives an overview of several integration architectures for dealing with the challenges that need to be overcome. While the book so far focuses on the usual structured relational data, the remaining chapters turn to unstructured data, an ever-increasing and important component of Big Data. One chapter on information extraction describes methods for dealing with the extraction of relations from free text and the web. Finally, BI users need tools to visualize and interpret new and complex types of information in a way that is compelling, intuitive, but accurate. The last chapter gives an overview of information visualization for decision support and text.
Since a reform in 2010, foreign investors can establish a Foreign-Invested Limited Partnership Enterprise (FILPE) in China together with Chinese or foreign investors. The FILPE can be combined with a domestic or foreign corporate general partner, thus allowing for a structure that offers the flexibility and taxation conditions of a partnership while protecting its investors against personal liability like a company. The book explores from the perspective of a foreign investor if the FILPE is an attractive investment vehicle by analysing whether it provides the characteristics that are internationally recognized as constituting a standard corporate form. Among these characteristics, the three that are most strongly interconnected and interdependent form the core of the analysis: legal personality, limited liability and transferable ownership interest. These are analyzed in context of China's restrictive framework of foreign investment regulations and enterprise organization law.
Managing Human Resources for Environmental Sustainability The Society for Industrial and Organizational Psychology (SIOP) is the premier membership organization for those practicing industrial and organizational psychology. The Society's mission is to enhance human well-being and performance in organizational and work settings by promoting the science, practice, and teaching of industrial and organizational (I-O) psychology. I-O psychologists apply research that improves the well-being and performance of people and the organizations that employ them. This involves everything from workforce planning, employee selection, and leader development to studying job attitudes and job motivation, implementing work teams, and facilitating organizational change. SIOP is a nonprofit organization with more than 6,000 members. While an independent organization with its own governance, SIOP is also a division within the American Psychological Association and an organizational affiliate of the Association for Psychological Science.
Quickly reference the answers you need to the most important clinical questions in orthopedics with Orthopedic Secrets. Fully updated throughout, this classic medical reference book covers the entire range of essential topics in orthopedics, organized by subspecialty, for rapid access to the knowledge you need for success both in practice and on board and recertification exams. - Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. - Zero in on key orthopedic information with a question-and-answer format, bulleted lists, mnemonics, and practical tips from the authors. - Enhance your reference power with "Key Points" boxes and lists of useful websites. - Review essential material efficiently with a "Top 100 Secrets" chapter, perfect for last-minute study or self-assessment. - Take a fresh, updated approach to orthopedics with new editors and authors from the world-class orthopedic program at the University of Pennsylvania. - Focus on the details most relevant to your needs through a new case-based approach that's perfect for student or resident reference/review, or for any practitioner looking for a broad overview of the field.
An Innovative Approach to Studying and Treating Cancer: Targeting pH describes one of the few characteristics of cancer that is not shared by normal tissues: the reversal or inversion of the pH gradient when intracellular pH becomes alkaline and extracellular pH becomes acid. This is now recognized as one of the most selective and differential hallmarks of all cancer cells and tissues, being the opposite of the condition found in normal tissues and a potential target in order to achieve either a stable disease or even regression with no toxicity. The book discusses topics such as lactic acid and its transport system in the pH paradigm, mechanisms to decrease extra cellular pH and increase intracellular pH, NHE-1 activity in cancer, carbonic anhydrases, vacuolar ATPase proton pump, and the sodium-bicarbonate cotransporter system. Additionally, it discusses complementary pharmacological interventions, cellular acidification and extracellular alkalinization as a new and integral approach to cancer treatment. - Analyzes the mechanisms that lead to the inversion of pH gradient in cancer tissues - Summarizes almost 100 years of research on pH inversion in cancer in one single source, discussing the most relevant and updated researches in the field - Proposes new efficient treatments against cancer using pH inversion mechanisms, either with new drugs like proton transport inhibitors and proton pump inhibitors (PTIs and PPIs) or with repurposed drugs
This book gives readers the tools they need to achieve work design that is ergonomically effective while remaining economically feasible. Whether studying work design/ergonomics in a college classroom, preparing for the Board of Certification in Professional Ergonomics (BCPE) exam, or working as a professional in the field, readers can depend on this book to provide them with the information they need. Work Design is a single source for ergonomics, work design, and work measurement. Its engineering orientation equips readers with practical design information and procedures; its explicit organization, conversational style, and clear explanations make it easy to read and understand. The book's many charts and graphics dynamically illustrate important concepts and principles, and its extensive references give readers confidence in the material.
Time and Poverty in Western Welfare States is the English-language adaptation of one of the most important contributions to welfare economics published in recent years. Professors Leibfried and Leisering offer a time-based (dynamic) analysis of the study of poverty, and suggest the need for a radical re-think of conventional theoretical and policy approaches. The core of this study is the empirical analysis of the life course of recipients of 'Social Assistance' in Germany, although the conclusions are put into a wider context of socio-economic and socio-political analysis and comparative observations are made with other countries, notably the USA. Time, Life and Poverty will be of interest to upper-level students, researchers and policy-makers in a wide range of social science disciplines, including: economics, social policy, sociology, psychology and European studies.
The book is considered a guideline for systemic personnel development in controlling of nationally and internationally active companies on the basis of a targeted development of competencies. In particular, the challenges posed by digitalization and globalization are considered and substantiated with the help of empirical studies. Employees and managers in controlling as well as HR managers in companies gain a deeper understanding of the necessity and the components of systematic personnel development. The goals are the formation of high-performance teams in controlling as well as the identification of personal career paths on the way to top management tasks as CFO. The focus of the personnel development model is on the transfer of the competence-oriented development approach, which, in addition to the traditionally considered technical and methodological competencies, also takes into account social and personal competencies as well as additional digital and intercultural competencies. The book is rounded off by a survey of the current situation, the definition of a target situation to be aimed at, the discussion of suitable further training measures and the monitoring of the level of competency achieved, and illustrates concrete career concepts.
Examines the post-1970s area of the Austrian economic tradition, from its revival to its contemporary directions and development. The book comprises texts on the relationship of Austrian economics to Institutionalism, Evolution, and Post-Keynesian economics to present a look at "the way forward".
Written by well-respected experts, this how-to guide provides patterns for the design of human computer human interaction (HCHI). An increasing number of applications are currently designed for use by more than one user, eg: multi-player games, interactive web sites, mobile phones, collaborative learning systems, interactive workspaces and smart environments. In these areas there is a shift from (HCI) human computer interaction to (HCHI) human computer human interaction. The role of patterns in this movement is twofold: 1st – patterns focus on the human user of the system; 2nd – patterns assist developers in the development process of groupware applications.
Write maintainable, extensible, and durable software with modern C++. This book is a must for every developer, software architect, or team leader who is interested in good C++ code, and thus also wants to save development costs. If you want to teach yourself about writing clean C++, Clean C++ is exactly what you need. It is written to help C++ developers of all skill levels and shows by example how to write understandable, flexible, maintainable, and efficient C++ code. Even if you are a seasoned C++ developer, there are nuggets and data points in this book that you will find useful in your work. If you don't take care with your code, you can produce a large, messy, and unmaintainable beast in any programming language. However, C++ projects in particular are prone to be messy and tend to slip into bad habits. Lots of C++ code that is written today looks as if it was written in the 1980s. It seems that C++ developers have been forgotten by those who preach Software Craftsmanship and Clean Code principles. The Web is full of bad, but apparently very fast and highly optimized C++ code examples, with cruel syntax that completely ignores elementary principles of good design and well-written code. This book will explain how to avoid this scenario and how to get the most out of your C++ code. You'll find your coding becomes more efficient and, importantly, more fun. What You'll Learn Gain sound principles and rules for clean coding in C++ Carry out test driven development (TDD) Discover C++ design patterns and idioms Apply these design patterns Who This Book Is For Any C++ developer and software engineer with an interest in producing better code.
Prostate Cancer Metabolism: From Biochemistry to Therapeutics shows the peculiarities of prostate cancer metabolism, emphasizing the targetable aspects – that have not been considered in conventional treatment protocols. The book specifically addresses treatment of the castration-resistant stage of prostate cancer proposing many repurposed drugs and nutraceuticals to complement, not replace, standard therapies. The large body of evidence supporting these concepts makes them deserving of further research and well-designed clinical trials. It discusses lipid, cholesterol, glutamine, and glucose metabolisms and their impact on prostate cancer. Additionally, it explains how current established drugs can be repurposed to improve treatment outcomes. The concepts set out in the book, that deal with cancer at the cellular/molecular level, help identify new avenues of research and treatments to pursue that do not affect well-being whilst offer consistent benefits. Since most practicing physicians have not studied basic biochemistry since medical school, each chapter begins with a brief review of the topic to facilitate an understanding of the metabolically-oriented approach to targeting prostate cancer. Conventional treatments are not discussed here since they are covered in textbooks and specialized updates that abound in the medical literature. It is a valuable resource for cancer researchers, oncologists, clinicians and members of biomedical field who want to learn more about prostate cancer metabolism and how to apply recent findings in the field to bedside. - Explains the basic aspects of prostate cancer metabolism, including its biochemistry which has a pivotal role in clinical practice - Discusses new drugs and nutraceuticals with a metabolism-centered approach - Offers practical bedside approach in combination with molecular and biochemical fundamentals to help readers identify and provide the best treatment to their patients
In the mountain of books that have been written about the Third Reich, surprisingly little has been said about the role played by the German nobility in the Nazis' rise to power. While often confidently referred to, the 'fateful' role played by the German nobility is rarely, if ever, investigated in any real detail. Nazis and Nobles now fills this gap, providing the first systematic investigation of the role played by the nobility in German political life between Germany's defeat in the First World War in 1918 and the consolidation of Nazi power in the 1930s. As Stephan Malinowski shows, the German nobility was too weak to prevent the German Revolution of 1918 but strong enough to take an active part in the struggle against the Weimar Republic. In a real twist of historical irony, members of the nobility were as prominent in the destruction of Weimar democracy as they were to be years later in Graf Stauffenberg's July 1944 bomb plot against Hitler. In this skilful portrait of an aristocratic world that was soon to disappear, Malinowski gives us for the first time the in-depth story of the German nobility's social decline and political radicalization in the inter-war years - and the troubled mésalliance to which this was to lead between the majority of Germany's nobles and the National Socialists.
Completely updated and in brilliant full color, Merritt's Neurology, 13th Edition, remains your reference of choice for outstanding guidance on neurologic protocols, treatment guidelines, clinical pathways, therapeutic recommendations, and imaging. Greatly reorganized for ease of use, the 13th Edition features more than 30 new chapters that keep will you up to date with every aspect of your field. Now for the first time, you’ll find dozens of video clips online that demonstrate the clinical signs and symptoms of neurologic disorders. Features: Visualize neurologic topics more easily than ever with an all-new, full-color format throughout. Benefit from the fresh perspective of new editors Dr. Elan Louis and Dr. Stephan Mayer, in addition to 180 expert contributors who offer guidance in their areas of expertise. Stay current with today’s hottest topics, thanks to new chapters on the global burden of neurological disease; magnetic resonance imaging and other imaging modalities; sleep studies; mild cognitive impairment; concussion; restless legs syndrome; seizures in children; HIV, fetal alcohol syndrome, and drug effects; and many more. Find the information you need more quickly thanks to a reorganized format. In 153 succinct chapters, you’ll find the essentials you need on signs and symptoms, diagnostic tests, and neurologic disorders of all etiologies. Watch approximately 40 video clips online to gain a clear understanding of the clinical signs and symptoms of neurologic disorders. Get the up-to-date information you need from the practical, readable resource that’s trusted and used by neurologists, primary care physicians, and residents.
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