This first monograph in the new AAPS book series concisely reviews important aspects of powder and particle systems and the critical quality attributes that should be used as a guide to future developments intended to maximize the control of product quality and performance. Drs. Hickey and Giovagnoli have written an essential primer for any scientists involved in powder or particle research and manufacturing. It is appropriate for those just entering the field or as a rapid reference for the experienced pharmaceutical scientist. The authors have both academic and industrial experience and the coverage includes solid state chemistry; crystallization; physical processes; particle size and distribution;particle interaction;manufacturing processes;quality by design;and a general discussion of the industry. Pharmaceutical Powder and Particles is intended to concisely review important aspects of powder and particle systems and the critical quality attributes that should be used as a guide to future developments intended to maximize the control of product quality and performance.
The formulation of Maxwell’s equations completely defines the connection between the electric field and the magnetic field, definitively unifying electricity and magnetism and at the same time providing a theoretical synthesis of all the experimental phenomena connected to these areas. In his revolutionary 1864 memoir where J.C. Maxwell presented his equations, he cites a handful of scientists, which were at the basis of his Theory. This book, in its first part, presents an insight on all these latter scientists, reconstructing the scientific network behind Maxwell’s unification and, in the second part, focuses on the Italians in such a network: Ottaviano Fabrizio Mossotti and Riccardo Felici, with a further insight on the connections between Maxwell and Italy and, in particular, Tuscany.
Clinical neuropsychology, i.e. the study of patients with cognitive disorders due to lesions of the central nervous system, has for many years been the leading or, in the case of language, the only source of knowledge about the neural basis of cognitive function. This state of affairs has changed considerably in the last two decades. The “cognitive revolution” has led to extensive developments in the modelling of cognitive functioning in normal subjects; at the same time, modern functional imaging techniques have provided new opportunities for the investigation of normal subjects engaged in cognitive tasks. These recent advances, together with other developments in the field of neurophysiology and experimental psychology, have been instrumental in the definition of a new field of investigation, called “cognitive neuroscience”. This increasing body of knowledge must be confronted, and whenever possible integrated, with the teachings of clinical neuropsychology. The aim of this book is to provide an introduction to this “basic science” from the vantage point of the possible applications to the practice of behavioural and cognitive neurology. It attempts to integrate cognitive neuroscience and the clinical practice of behavioural and cognitive neurology. For this reason, the review of the classical syndrome of neuropsychology, such as aphasia, unilateral neglect and dementia, is preceded by a summary of current cognitive models. The first section is thus devoted to selective summaries of current models of cognitive functions and of their neurological correlates; the second discusses diagnostic issues; the third provides an overview of clinical presentations, and attempts an integration with the first section; finally, the fourth section is devoted to treatment and management issues./a
This first monograph in the new AAPS book series concisely reviews important aspects of powder and particle systems and the critical quality attributes that should be used as a guide to future developments intended to maximize the control of product quality and performance. Drs. Hickey and Giovagnoli have written an essential primer for any scientists involved in powder or particle research and manufacturing. It is appropriate for those just entering the field or as a rapid reference for the experienced pharmaceutical scientist. The authors have both academic and industrial experience and the coverage includes solid state chemistry; crystallization; physical processes; particle size and distribution;particle interaction;manufacturing processes;quality by design;and a general discussion of the industry. Pharmaceutical Powder and Particles is intended to concisely review important aspects of powder and particle systems and the critical quality attributes that should be used as a guide to future developments intended to maximize the control of product quality and performance.
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