A complete explanation of the issues that determine private firmvalue Principles of Private Firm Valuation combines recent academicresearch and practical real-world experience to help readers betterunderstand the multitude of factors that determine private firmvalue. For the financial professional serving private firms-who areincreasingly being called upon to give advice on issues related tofirm valuation and deal structure-this comprehensive guidediscusses critical topics, including how firms create value and howto measure it, valuing control, determining the size of themarketability discount, creating transparency and the implicationsfor value, the value of tax pass-through entities versus a Ccorporation, determining transaction value, and the valuationimplications of FASB 141 (purchase price accounting) and 142(goodwill impairment). Dr. Stanley J. Feldman (Lowell, MA) is Associate Professor ofFinance at Bentley College, where he currently teaches courses incorporate finance with a focus on business valuation and businessstrategy at both the graduate and undergraduate levels. He is amember of the FASB Valuation Resource Group and is Chairman andcofounder of Axiom Valuation Solutions.
A complete explanation of the issues that determine private firmvalue Principles of Private Firm Valuation combines recent academicresearch and practical real-world experience to help readers betterunderstand the multitude of factors that determine private firmvalue. For the financial professional serving private firms-who areincreasingly being called upon to give advice on issues related tofirm valuation and deal structure-this comprehensive guidediscusses critical topics, including how firms create value and howto measure it, valuing control, determining the size of themarketability discount, creating transparency and the implicationsfor value, the value of tax pass-through entities versus a Ccorporation, determining transaction value, and the valuationimplications of FASB 141 (purchase price accounting) and 142(goodwill impairment). Dr. Stanley J. Feldman (Lowell, MA) is Associate Professor ofFinance at Bentley College, where he currently teaches courses incorporate finance with a focus on business valuation and businessstrategy at both the graduate and undergraduate levels. He is amember of the FASB Valuation Resource Group and is Chairman andcofounder of Axiom Valuation Solutions.
This fully revised and updated seventh edition provides a thorough overview and introduction to hearing science. Covering topics such as conductive and cochlear mechanisms, auditory pathways, and binaural and spatial hearing and including some new and updated diagrams and figures, this book serves as a great resource for both graduate students and professionals working in audiology and other fields like psychology, neuroscience, otolaryngology, and linguistics. This improved edition reflects the ever-changing field of hearing science.
**Selected for Doody's Core Titles® 2024 in Dentistry** Learn to prevent, recognize, and manage complications of local anesthesia administration. Written by Dr. Stanley Malamed, the leading expert on anesthesia in dentistry, the Handbook of Local Anesthesia, 7th Edition covers all the latest advances in science, instrumentation, and pain control techniques. From basic concepts to specific injection techniques, from dosage charts to the proper care and handling of equipment, this how-to guide provides in-depth, full-color coverage of key anesthesia topics, including specific hazards and errors in technique that may result in complications. Recognized as THE local anesthesia textbook in dentistry for over 30 years, the seventh edition has been thoroughly updated with the latest in safe anesthesia practices in dentistry. - Written by Dr. Stanley Malamed, one of the most in-demand and globally recognized experts on dental anesthesia and sedation. - Full-color photographs and line drawings enhance important points throughout book. - Step-by-step procedures cover the techniques for administering intraoral anesthesia. - Detailed descriptions of routes of anesthesia administration included throughout text. - Logical Organization of content divides book into four parts including –Drugs, The Armamentarium, Techniques of Regional Anesthesia in Dentistry, and Complications, Legal Considerations, Questions, and the Future - NEW! Updated and enhanced content throughout reflects latest research evidence. - NEW! Two added chapters cover problems in achieving pain control and their solutions; and recent advances in local anesthesia. - NEW! Addition of an Expert Consult Site allows you to search the entire book electronically.
From the development of each vaccine to its use in reducing disease, Plotkin's Vaccines, 7th Edition, provides the expert information you need to provide optimal care to your patients. This award-winning text offers a complete understanding of each disease, as well as the latest knowledge of both existing vaccines and those currently in research and development. Described by Bill Gates as "an indispensable guide to the enhancement of the well-being of our world," Plotkin's Vaccines is a must-have reference for current, authoritative information in this fast-moving field. - Includes complete information for each disease, including clinical characteristics, microbiology, pathogenesis, diagnosis, and treatment, epidemiology, and public health and regulatory issues – plus complete information for each vaccine, including its stability, immunogenicity, efficacy, duration of immunity, adverse events, indications, contraindications, precautions, administration with other vaccines, and disease-control strategies. - Analyzes the cost-benefit and cost-effectiveness of different vaccine options. - Helps you clearly visualize concepts and objective data through an abundance of tables and figures. - Covers the new oral cholera and zoster vaccines, as well as newly licensed meningococcal group B vaccines and a newly licensed dengue vaccine. - Brings you up to date on successful human trials of Ebola vaccines, an enterovirus 71 vaccine licensed in China, and new recommendations and changes to polio vaccines. - Features a new chapter on maternal immunization. - Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
From the latest vaccination evidence, recommendations, and protocols . . . to new vaccine development and the use of vaccines in reducing disease, Plotkin's Vaccines, 8th Edition, covers every aspect of vaccination. Now completely revised and updated from cover to cover, this award-winning text continues to provide reliable information from global authorities, offering a complete understanding of each disease, as well as the latest knowledge of both existing vaccines and those currently in research and development. Described by Bill Gates as "an indispensable guide to the enhancement of the well-being of our world," Plotkin's Vaccines is a must-have reference for current, authoritative information in this fast-moving field. - Contains all-new chapters on COVID-19, vaccine hesitancy, and non-specific effects of vaccines, as well as significantly revised content on new vaccine technologies such as mRNA vaccines, emerging vaccines, and technologies to improve immunization. - Presents exciting new data on evolution of adjuvants across the centuries, dengue vaccines, human papillomavirus vaccines, respiratory syncytial virus vaccines, tuberculosis vaccines, and zoster vaccines. - Provides up-to-date, authoritative information on vaccine production, available preparations, efficacy and safety, and recommendations for vaccine use, with rationales and data on the impact of vaccination programs on morbidity and mortality. - Provides complete coverage of each disease, including clinical characteristics, microbiology, pathogenesis, diagnosis, and treatment, as well as epidemiology and public health and regulatory issues. - Keeps you up to date with information on each vaccine, including its stability, immunogenicity, efficacy, duration of immunity, adverse events, indications, contraindications, precautions, administration with other vaccines, and disease-control strategies. - Covers vaccine-preventable diseases, vaccine science, and licensed vaccine products, as well as product technologies and global regulatory and public health issues. - Analyzes the cost-benefit and cost-effectiveness of different vaccine options. - Helps you clearly visualize concepts and objective data through an abundance of tables and figures. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
Completely revised and updated, this respected reference offers comprehensive and current coverage of every aspect of vaccination-from development to use in reducing disease. It provides authoritative information on vaccine production, available preparations, efficacy, and safety...recommendations for vaccine use, with rationales...data on the impact of vaccination programs on morbidity and mortality...and more. And now, as an Expert Consult title, it includes a companion web site offering this unparalleled guidance where and when you need it most! Provides a complete understanding of each disease, including clinical characteristics, microbiology, pathogenesis, diagnosis, and treatment, as well an epidemiology and public health issues. Offers comprehensive coverage of both existing vaccines and vaccines currently in the research and development stage. Examines vaccine stability, immunogenicity, efficacy, duration of immunity, adverse events, indications, contraindications, precautions, administration with other vaccines, and disease control strategies. Analyses the cost-benefit and cost-effectiveness of vaccines. Discusses the proper use of immune globulins and antitoxins. Illustrates concepts and objective data with approximately 600 tables and figures. Includes access to a companion web site offering the complete contents of the book - fully searchable - for rapid consultation from anyplace with an Internet connection.
Nueva edición de la obra de referencia en anestesia aplicada a la práctica odontológica de la mano del Dr. Stanley Malamed, reconocida autoridad de prestigio internacional en la disciplina. La obra llega ahora a su séptima edición, después de un largo recorrido desde el el año 1978 en que empezó su andadura. Así, una vez más "Handbook of local anesthesia" se posiciona como el best seller en su campo, recogiendo las últimas novedades tanto farmacológicas como tecnológicas para conseguir el doble objetivo que todo odontólogo quiere conseguir: eliminar totalmente el dolor en el paciente tanto en el proceso como en el momento de aplicarle el anestésico. De nuevo se presenta como una guía "how to" para la correcta práctica de la anestesia en la práctica odontológica, abarcando desde los conceptos básicos de las técnicas de inyección hasta las recomendaciones de dosis para cada uno de los procedimientos y el adecuado mantenimiento y uso del instrumental. La obra magníficamente ilustrada y a todo color aborda también todos aquellos casos en que se producen complicaciones tras la aplicación de un anestésico. Completa actualización de la inyección del ligamento periodontal (PDL)-incluyendo los métodos de administración del anestésico controlados mediante ordenador (c-CLAD). Administración de inyecciones locales de articaína (anestésico local de acción corta) mediante infiltraciones mandibulares en los adultos. Administración de soluciones tampón con los anestésicos para conseguir: disminuir el dolor en el momento de la inyección, disminuir el tiempo hasta el inicio del efecto anestésico y si cabe, una mayor intensidad de dicho efecto una vez producido. Completa actualización de los procedimientos para la administración de anestesia intraoral, siguiendo siempre la metodología del "step by step". Actualización y revisión de las diferentes técnicas para el control del dolor Inclusión de imágenes anatomo-clínicas más relevantes para comprender la base de las diferentes técnicas. Nueva edición del texto de referencia en la disciplina, con más de 40 años de trayectoria en el mercado y obra de primera elección para todo aquel que necesite conocer tanto los fármacos como las técnicas de aplicación más novedosas en todos los procesos odontológicos que precisen de anestesia. La obra se estructura en un total de 4 grandes secciones y se presenta como una guía "how to" que proporciona una cobertura en profundidad de todos los aspectos relativos a la anestesia, incluyendo aquellos riesgos y errores que pueden llevar a complicaciones. Cabe destacar la inclusión de dos nuevos capítulos; uno de ellos dedicado a los problemas que pueden aparecer para controlar el dolor y el otro dedicado a los avances más recientes producidos en el campo de la anestesia local. Así mismo, se ha procedido a la renovación total de dos de los capítulos ya existentes (el relativo a las consideraciones anestésicas en las diferentes especialidades odontológicas y el de las complicaciones locales). En último término, destacar que se han incluido nuevas imágenes anatomo-clínicas que son especialmente relevantes para comprender la base de las diferentes clínicas.
This book provides a broad overview of all aspects of modern lymphokine research. It begins with the ways in which lymphokines play a role in the activation of the immune response and concludes with their participation in various facets of host defense. It devotes special attention to structure, mechanism of action, and range application. In addition, this fascinating work also shows how lymphokines are involved in other physiologic responses, such as reparative reactions involving fibrosis and angiogenesis. This is an excellent resource for students and investigators in the biomedical sciences, as well as clinicians who require up-to-date information about our current understanding of immune processes.
Offering a state-of-the-art, authoritative summary of the most relevant scientific and clinical advances in the field, Principles and Practice of Movement Disorders provides the expert guidance you need to diagnose and manage the full range of these challenging conditions. Superb summary tables, a large video library, and a new, easy-to-navigate format help you find information quickly and apply it in your practice. Based on the authors' popular Aspen Course of Movement Disorders in conjunction with the International Parkinson and Movement Disorder Society, this 3rd Edition is an indispensable resource for movement disorder specialists, general neurologists, and neurology residents. - Explores all facets of movement disorders, including the latest rating scales for clinical research, neurochemistry, clinical pharmacology, genetics, clinical trials, and experimental therapeutics. - Provides the essential information you need for a clinical approach to diagnosis and management, with minimal emphasis on basic science. - Reflects recent advances in areas such as the genetics of Parkinsonian and other movement disorders, diagnostic brain imaging, new surgical approaches to patients with movement disorders, and new treatment guidelines for conditions such as restless legs syndrome. - Features a reader-friendly, full-color format, with plentiful diagrams, photographs, and tables. - Includes access to several hundred updated, professional-quality video clips that illustrate the manifestations of all the movement disorders in the book along with their differential diagnoses.
Long was I hugg'd close-long and long. Immense have been the preparations for me, Faithful and friendly the arms that have help'd me. Cycles ferried my cradle, rowing and rowing like friendly boatmen. For room to me stars kept aside in their own rings, They sent influences to look after what was to hold me. Before I was born out of my mother, generations guided me, My embryo has never been torpid, nothing could overlay it. -Walt Whitman, "Song of Myself" The womb is the seat of all mammalian life. In pregnancy, the uterus acquires this impor tance with the arrival of the fertilized egg, which takes up residence for periods ranging from about 2 weeks in the opossum to about 2 years in the elephant. The arrival of the embryo signals a crucial time for the establishment of pregnancy. For several days the blas tocyst remains free in the uterine lumen, where it depends on uterine secretions for its sur vival and differentiation. During this time, essential changes in the endometrium take place in preparation for attachment of the blastocyst and implantation. Early embryonic loss is an economic problem of global proportions in animal husbandry, where, in pigs and cattle for example, some 30% of all fertilizations fail to result in a pregnancy. In humans this figure may be even higher, and estimates of early spontaneous abortions range from 40 to 60% of all conceptions.
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