Ambiguous genitalia can be associated with disorders of sex development (DSD). DSD occurs when a person is born with discordant genetic, gonadal, or anatomic sex. Here we discuss typical-appearing external genital appearance in unaffected males and females followed by descriptions of ambiguous genitalia in newborns with 46,XY DSD, 46,XX DSD, syndromes associated with multiple congenital anomalies including, but not limited to, ambiguous genitalia, ovotesticular DSD, and mixed gonadal dysgenesis in newborns who possess a Y chromosome. We provide guidance to proceed with a clinical work-up to differentiation between types of DSD that result in ambiguous genitalia at birth. Finally, we discuss how gender assignments are made for newborns with DSD including ambiguous genitalia.
Many books and courses tackle natural language processing (NLP) problems with toy use cases and well-defined datasets. But if you want to build, iterate, and scale NLP systems in a business setting and tailor them for particular industry verticals, this is your guide. Software engineers and data scientists will learn how to navigate the maze of options available at each step of the journey. Through the course of the book, authors Sowmya Vajjala, Bodhisattwa Majumder, Anuj Gupta, and Harshit Surana will guide you through the process of building real-world NLP solutions embedded in larger product setups. You’ll learn how to adapt your solutions for different industry verticals such as healthcare, social media, and retail. With this book, you’ll: Understand the wide spectrum of problem statements, tasks, and solution approaches within NLP Implement and evaluate different NLP applications using machine learning and deep learning methods Fine-tune your NLP solution based on your business problem and industry vertical Evaluate various algorithms and approaches for NLP product tasks, datasets, and stages Produce software solutions following best practices around release, deployment, and DevOps for NLP systems Understand best practices, opportunities, and the roadmap for NLP from a business and product leader’s perspective
Fourteen-year-old Ashwathy heads the FBI branch of Kuttipuram, Kerala Of course, there is no such thing as the FBI branch of Kuttipuram, Kerala, but Ashwathy Venugopalan always believes in the impossible—life is more entertaining that way. And things only get more impossible in Ashwathy's life when God arrives in a boot and requests her to investigate the murder of a woman in her town. Can Ashwathy, the atheist, crack her first case with God by her side?
Ambiguous genitalia can be associated with disorders of sex development (DSD). DSD occurs when a person is born with discordant genetic, gonadal, or anatomic sex. Here we discuss typical-appearing external genital appearance in unaffected males and females followed by descriptions of ambiguous genitalia in newborns with 46,XY DSD, 46,XX DSD, syndromes associated with multiple congenital anomalies including, but not limited to, ambiguous genitalia, ovotesticular DSD, and mixed gonadal dysgenesis in newborns who possess a Y chromosome. We provide guidance to proceed with a clinical work-up to differentiation between types of DSD that result in ambiguous genitalia at birth. Finally, we discuss how gender assignments are made for newborns with DSD including ambiguous genitalia.
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