Raging Heart is so revealing that the book itself became part of the actual O.J. Simpson murder trial. It is the only book to trace the path of O.J. and Nicole’s fatal love story through the eyes of the people who really knew them. Acclaimed journalist Sheila Weller gained the unprecedented cooperation of Nicole Brown Simpson’s family, and had exclusive access to O.J. and Nicole’s friends who reveal private information here for the first time. Though the story that unfolds in Raging Heart was never fully explored in court, the revelations from its incisive reporting sent shock waves through the trial. Raging Heart is full of explosive information from people who knew, but couldn’t—or wouldn’t—tell their stories on the witness stand. As vivid as a home movie, Raging Heart is an explicit, heartrending look behind the verdict of the century—and the one book the O.J. Simpson jurors would be astonished to read.
The only book dedicated to physiologically-based pharmacokinetic modeling in pharmaceutical science Physiologically-based pharmacokinetic (PBPK) modeling has become increasingly widespread within the pharmaceutical industry over the last decade, but without one dedicated book that provides the information researchers need to learn these new techniques, its applications are severely limited. Describing the principles, methods, and applications of PBPK modeling as used in pharmaceutics, Physiologically-Based Pharmacokinetic (PBPK) Modeling and Simulations fills this void. Connecting theory with practice, the book explores the incredible potential of PBPK modeling for improving drug discovery and development. Comprised of two parts, the book first provides a detailed and systematic treatment of the principles behind physiological modeling of pharmacokinetic processes, inter-individual variability, and drug interactions for small molecule drugs and biologics. The second part looks in greater detail at the powerful applications of PBPK to drug research. Designed for a wide audience encompassing readers looking for a brief overview of the field as well as those who need more detail, the book includes a range of important learning aids. Featuring end-of-chapter keywords for easy reference a valuable asset for general or novice readers without a PBPK background along with an extensive bibliography for those looking for further information, Physiologically- Based Pharmacokinetic (PBPK) Modeling and Simulations is the essential single-volume text on one of the hottest topics in the pharmaceutical sciences today.
Sioui has produced a work not only of metahistory but of moral reflections. He contrasts Euroamerican ethnocentrism and feelings of racial superiority with the Amerindian belief in the "Great Circle of Life" and shows that human beings must establish intellectual and emotional connections with the entire living world if they hope to achieve abundance, quality, and peace for all. Sioui is proud to be a Huron and an Amerindian and is fully aware of the injustices that the aboriginal people of North America have suffered - and continue to suffer - at the hands of Euroamericans. He is convinced that the greatness of Amerindians does not lie only in the past but that Native peoples will play an even more important role in the future by providing ideas essential to creating aviable way of life for North America and the world. While this is a polemical work, Sioui never descends to recrimination or vituperative condemnation, even when that might seem justified. Instead, he has given us a polemic that is written at the level of philosophy.
When a lion cub named Leonardo falls in love with a turtle named Turnip, she takes him for a journey through the mysteries of her world in the depths of the ocean.
A little wooly teddy bear, a long journey to the ends of the earth, and magical complicity between words and images, this story reveals Mr. Man's great heart.
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