Understand a vital new bioanalytical technique with this comprehensive introduction to measuring temperature on the cellular scale Most organisms have highly controlled body temperatures, fluctuations in which are therefore sensitive indicators of changes in body function. In recent years, the development of fluorescent molecular thermometers and related intracellular temperature probes has enabled researchers to track these fluctuations at the cellular rather than the organismic level, opening up a whole new field of study in cell and molecular biology. Intracellular Thermometry with Fluorescent Molecular Thermometers provides bioanalytical researchers with an introduction to these technologies and their current and future applications. Starting off with a discussion of temperature as a key factor in biological regulation, it provides an authoritative overview of available fluorescent temperature probes, their characteristics and potential applications. Intracellular Thermometry with Fluorescent Molecular Thermometers readers will also find: Step by step instructions for constructing an intracellular thermometry experiment and validating results Comprehensive discussion of existing applications A vision for the future development of thermal biology as an independent discipline Authored by a pioneer in the field of intracellular thermometry, Intracellular Thermometry with Fluorescent Molecular Thermometers is ideal for researchers in analytical chemistry, cell biology, molecular biology, biophysics, or any related subjects.
Offers a comprehensive overview of NAND flash memories, with insights into NAND history, technology, challenges, evolutions, and perspectives Describes new program disturb issues, data retention, power consumption, and possible solutions for the challenges of 3D NAND flash memory Written by an authority in NAND flash memory technology, with over 25 years’ experience
Braid theory and knot theory are related via two famous results due to Alexander and Markov. Alexander's theorem states that any knot or link can be put into braid form. Markov's theorem gives necessary and sufficient conditions to conclude that two braids represent the same knot or link. Thus, one can use braid theory to study knot theory and vice versa. In this book, the author generalizes braid theory to dimension four. He develops the theory of surface braids and applies it tostudy surface links. In particular, the generalized Alexander and Markov theorems in dimension four are given. This book is the first to contain a complete proof of the generalized Markov theorem. Surface links are studied via the motion picture method, and some important techniques of this method arestudied. For surface braids, various methods to describe them are introduced and developed: the motion picture method, the chart description, the braid monodromy, and the braid system. These tools are fundamental to understanding and computing invariants of surface braids and surface links. Included is a table of knotted surfaces with a computation of Alexander polynomials. Braid techniques are extended to represent link homotopy classes. The book is geared toward a wide audience, from graduatestudents to specialists. It would make a suitable text for a graduate course and a valuable resource for researchers.
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