Known to generations of cinema-lovers as the evergreen hero of blockbuster hits like Dil Ek Mandir, Ayee Milan ki Bela, Arzoo and Sangam, Rajendra Kumar Tuli was truly the ‘Jubilee Star’ of Hindi cinema in the 1960s. Jubilee Kumar is the so-far-untold story of the man behind the superstar – one who went from riches to rags early in life, but whose determination, prudence and humility saw him surmount countless hurdles, and win the affection and admiration of colleagues and fans alike. A dispossessed refugee following Partition, Kumar’s struggles intensified as he travelled from Sialkot to Bombay to try his luck in films, suffering homelessness and hunger before he got a break as an assistant director. Overcoming both prejudice in the industry and his own insecurities, he eventually rose to unimaginable fame and popularity as a leading man in films and a respected producer. Touching candidly upon his life both on-screen and off it, this intimate account reveals Kumar – often through his own reminiscences and the recollections of others – as a hard-headed businessman, a generous and empathetic senior colleague, a gallant co-star to his female leads, a good-natured rival to peers and, above all, an upright and principled family man who rose above the many temptations of life in the Indian film industry. A riveting tale of struggle and stardom, fame and disillusionment, love, heartbreak and loss, Jubilee Kumar unwraps the many layers of an icon whose achievements and charisma few of his rivals or successors have been able to match.
It is becoming increasingly important to examine the relationship between the outcomes of a clinical trial and the costs of the medical therapy under study. The results of such analysis can affect reimbursement decisions for new medical technologies, drugs, devices or diagnostics. It can aid companies seeking to make claims about the cost-effectiveness of their product, as well as allowing early consideration of the economic value of therapies which may be important to improving initial adoption decisions. It is also vital for addressing the requirements of regulatory bodies. Economic Evaluation in Clinical Trials provides practical advice on how to conduct cost-effectiveness analyses in controlled trials of medical therapies. This new edition has been extensively rewritten and revised; topics discussed range from design issues such as the types of services that should be measured and price weights, to assessment of quality-adjusted life years. Illustrative materials, case histories and worked examples are included to encourage the reader to apply the methods discussed. These exercises are supported with datasets, programmes and solutions made available online.
This book takes readers on a journey through the evolution of agricultural communities in southern India, from their historical roots to the recent global neo-liberal era. It offers insights into a unique combination of themes, with a particular focus on agrarian change and urbanisation, specifically in the state of Karnataka where both aspects are significant and co-exist. Based on case studies from Karnataka in South India, the book presents a regional yet integrated multi-disciplinary framework for analysing the persistence, resilience and future of small farmer units. In doing so, it charts possible futures for small farm holdings and identifies means of integrating their progress and sustainability alongside that of the rest of the economy. Further, it provides arguments for the relevance of small holdings in connection with sustainable livelihoods and welfare at the grass roots, while also catering to the welfare needs of society at the macro level. The book makes a valuable contribution to the scholarship of agrarian as well as peri-urban transdisciplinary literature. For agrarian academics, students and the teaching community, the book’s broad and topical coverage make it a valuable resource. For development practitioners and for those working on issues related to urbanisation, urban peripheries and the rural–urban interface, this book offers a new perspective that considers the primary sector on par with the secondary and tertiary. It also offers an insightful guide for policymakers and non-government organisations working in this area.
According to the current scenario, the reduction of the time it takes for a product to launch in the market is important for the company’s success. Colloidal and supramolecular delivery systems are designed to conquer the numerous pharmacokinetic impediments that result in untimely inactivation, reduced drug absorption, redundant circulation, and eradication. This book is designed to guide you towards the colloidal and supramolecular drug delivery systems along with their classifications, methods of preparations, their characterization and the regulatory strategies that are adopted to launch a nano-system based formulation in the markets. This book will give knowledge to researchers and graduate students regarding colloidal and supramolecular drug delivery systems and their applications in numerous fields, and can serve as a comprehensive guide and reference for their research and study.
This book demonstrates that gender is a key component of conflict and peace discourse. The marginalization of women in conflict and peace is all pervasive. Kashmir is a mirror image of this global scenario. Kashmiri women aided the militant movement in significant ways though they did not take part in direct combat. They played key roles to sustain and nourish the movement – as protestors, protectors and motivators, and facilitators. Their experiences of participation in the conflict, however, remain subdued by the dominant masculinist discourse. Kashmiri women are excluded from the militancy discourse as contributors as well as from peacemaking discourse as stakeholders. The study interrogates theory and practice of women's participation in conflict and argues that changed gender-roles during conflict do not necessarily revolutionize socially ascribed norms. The book also examines the experiences of women in sustaining conflict to make a case for their due place in negotiating formal peace.
Global Perspectives of the Transmission of Zoonotic RNA Viruses from Wild Animal Species to Humans: Zoonotic, Epizootic, and Anthropogenic Transmission Viral Pathogens elaborates on the current knowledge surrounding the transmission of zoonotic RNA viruses from different wild animal species to humans, including updates on the reverse transmission of pathogens to humans across the globe, with coverage of rodents, pigs, birds and primates. This reference goes beyond the phenomena occurring in African and American regions to provide further study of zoonotic pathogens from the entire world, including various parts of Asia such as India. The book comprehensively covers new knowledge on many diverse wild primate species for a global perspective on the phenomena of cross-species transmissions of pathogenic RNA viruses. Against the backdrop of the current global Covid-19 pandemic, this reference helps solve the problem of incomplete knowledge on global epidemiology of zoonotic RNA viruses. RNA viruses have pandemic, epidemic and epizootic potentials caused by Influenza viruses, Avian Influenza viruses, and other infectious viruses. - Provides global coverage of the transmission of zoonotic infectious RNA viruses with epidemic and pandemic potentials in natural settings, with a new focus on India which is largely overlooked - Provides data related to the transmission of different zoonotic RNA viruses, SIVs, SFVs and Influenza viruses in India - Delivers background information on related RNA viruses like SARS, SRASCoV2, HIV-1, HIV-2, restriction factors, endogenous retroviruses and lentiviruses and other environmental data which is relevant for a comprehensive understanding of zoonotic events across the world
Two Muslim teens in Texas fight for access to abortion while one harbors a painful secret in this funny and heartfelt near-future speculative novel perfect for fans of Unpregnant. In a not-too-distant America, abortions are prosecuted and the right to choose is no longer an option. But best friends Laylah and Noor want to change the world. After graduating high school, they’ll become an OBGYN and a journalist, but in the meantime, they’re working on an illegal guide to abortion in Texas. In response to the unfair laws, underground networks of clinics have sprung up, but the good fight has gotten even more precarious as it becomes harder to secure safe medication and supplies. Both Layla and Noor are passionate about getting their guide completed so it can help those in need, but Laylah treats their project with an urgency Noor doesn’t understand—that may have something to do with the strange goings-on between their mosque and a local politician. Fighting for what they believe in may involve even more obstacles than they bargained for, but the two best friends will continue as they always have: together.
The environment and climate change are the most important issues in the modern world. This book will contribute to a better understanding of concepts in the field of the environment and other related fields, as well as assisting students in scoring higher marks in a number of competitive exams. This book is focused on the environment, including subjects like environmental ecology, hydrogeology, bio-diversity, natural hazards and disaster management, climate change and other environmental problems. Some of the topics discussed in the book include environmental laws, soil science, natural disasters, the Earth's internal structure, sea floor spreading, plate tectonics, food chains, carbon sequestration, agriculture, ecological succession, and government and non-governmental organizations working in the field of environmental issues, among others.
Concepts and Methodology in Cancer Diagnostics: An Immunological, Biochemical and Molecular Approach provides an exclusive combination of all basics and recent techniques, methodology, and advancements in the field of cancer diagnostics. With a strong focus on the procedures and techniques involved in cancer diagnostics, content also gives insights into the molecular tests required for different tumors for the administration of targeted drugs and precision medicine. In 11 chapters. The book also introduces the methods and technologies based on DNA and RNA based biomarkers, biochemical and immunological markers, genetic signatures, epigenetic changes and exosomes in blood, and tissue and body fluids. Readers will find a compilation of imperative topics and lists of the necessary materials and reagents needed, step-by-step instructions, readily reproducible laboratory protocols, as well as tips on troubleshooting and known pitfalls. This book is a valuable resource for medical professionals and researchers who want to understand the concepts of validated protocols and methodologies in diagnosing cancer, its prognosis, and predictive value. - Discusses and provides solutions for quality control procedures in antibody tests in cancer diagnostics - Gives insights into the limitations and biasness of biomarker testing, specifically immunohistochemical and molecular markers - Provides procedures and addresses the challenges related to quality control, proficiency testing, accuracy, and precision of biomarker testing in cancer - Explores numerous methods used in basic and diagnostic laboratories to characterize cancer-related biomarkers, including cancer risk assessment, diagnosis, and determination of cancer progression
This concise and comprehensive guide describes the complexities, key concepts and mechanisms of the immune system in a simplified manner. The book provides a clear and accessible overview of the body’s defence mechanisms, covering various aspects such as the structure and function of immune cells, the mechanisms of antigen recognition and response, the regulation of immune responses through the release of cytokines, and dysfunctions of the immune system which lead to autoimmunity and hypersensitivity. Additionally, it covers different immunological techniques and the latest developments in immunotherapy, including the use of monoclonal antibodies. The multiple-choice questions and answers provided at the end of each chapter will further enhance the understanding of the book’s readership.
There is a need of strengthening the global and local response to cope with the threat of climate change and adverse effects of rising anthropogenic activities in the mountain ecosystem. This book provides an up-to-date and comprehensive scientific and technical knowledge based on climate and land cover change impact assessment, adaptation and mitigation strategies in the Indian Himalayan watershed. The text updates the understanding scientific analysis to promote evidence-based policy formulation at regional and local levels. It can be used as reference materials with regards to climate and land cover change for those new learners interested in the mountainous region. This comprehensive book covers a wide range of potential research areas including climate change scenarios, science and its applications, adaptation to climate change-theory and assessment, water resources, agriculture, forest, biodiversity, and ecosystems, indigenous knowledge etc.
This book presents a comprehensive analysis of the intricate security situation prevailing in Balochistan. It explores and establishes correlations between the internal structural vulnerabilities and fault lines of the Pakistani state with the external influences exerted on the region. Employing a rigorous examination of both primary and secondary data, the volume critically examines the multifaceted nature of organised violence in Balochistan. In addition to separatist movements, the presence of religious militancy and cross-border terrorism is thoroughly examined. The book delves into the external involvement of regional and global powers in the intricate tapestry of violence within Balochistan, thereby shedding light on the emerging geopolitical landscape and the corresponding power dynamics in the region. It also analyses how the implementation of largescale developmental initiatives, particularly facilitated by China under the auspices of the China–Pakistan Economic Corridor (CPEC), has elevated the geostrategic significance of Balochistan while simultaneously entangling it in the vortex of regional power politics. This volume will be of interest to scholars and researchers specializing in geopolitics, International Relations, and South Asian studies.
Wings Of Rhapsody Wings Of Rhapsody - A Dalliance Of Poems is an anthology of poems written by Mumbai based poetess Ms. Seema K Jayaraman. This collection is an eclectic mix of poems written over a period of three decades. Seema is a visual artist painting with words. 'Seema writes with a naturalistic, lyrical style, her work on the page begs to be read aloud. Her work hearkens to a romantic tradition, drawing on landscape and nature her craft is a contemporary one.’ - Guest Curator Ciarán Hodgers, Leaveners’ ‘Poets’ Corner’ UK introduces Seema K Jayaraman as showcased Poet of the month December 2015. 'Seema's poems are like photographs in words, one can open the book to any page for a feeling of true human history. lots of love and best wishes for the book!, -Mana (Spiritual healer, Popular author of Soul Science) 'Seema's poems sometimes feel like song, they have a beat, some are mystical..' - Aneish Kumar (MD, BONY, Mumbai) 'Seema's poems are thought- provoking, they churn you up with lucid images and strong emotions. A book of poems which heals. I loved it.' Keep writing.....and healing...Love.’ -Dr Trupti Jayin (Clinical psychologist, PLR expert) 'Seema, a poet / poetess like you only come around every 100 years or more, this is your star, your destiny. Your ink is indeed blessed.' - John Kavangah, UK (Poet, Author, Critic) 'Mesmerising! Original and ingenious crafting of words and images. Delight to read and savor.' - Oormila V Prahlad, Australia (Artist, Poetess and Accomplished Pianist)
Can’t sleep soundly? Don’t feel like stepping out of the house? Having suicidal thoughts? You might be depressed and don’t know it yet. According to a WHO study, a mindboggling 35.9 percent of India suffers from Major Depressive Episodes (MDE). Yet depression remains a much evaded topic, quietly brushed under the carpet by most of us. In Beating the Blues, India’s leading clinical psychologist, psychotherapist, and trauma researcher Seema Hingorrany provides a comprehensive, step-by-step guide to treating depression, examining what the term really means, its signs, causes, and symptoms. The book will equip you with: • Easy-to-follow self-help strategies and result-oriented solutions • Ways of preventing a depression relapse • Everyday examples, statistics, and interesting case-studies • Workbooks designed for Seema’s clients With clients ranging from celebrities and models to teenagers, married couples, and children, Seema decodes depression for you. Informative and user-friendly, with a foreword by Indu Shahani, the Sheriff of Mumbai, Beating the Blues is an invaluable guide for those who want to deal with depression but don’t know how
This book helps clinicians to optimally and appropriately utilize homocysteine levels in the diagnosis, prediction and management of and research into vascular disease and many other conditions. It also familiarizes readers with the pathophysiology and clinical implications of hyperhomocysteinemia. Laboratory investigations are gaining importance in the diagnosis and prognosis of patients, and as such, scientists and laboratorians are constantly attempting to identify new markers that will help in earlier diagnosis and better prognostication of conditions with high morbidity and mortality, as well as high prevalence. According to the WHO, developing countries are home to 80% of patients with coronary artery disease (CAD) and stroke – conditions with a mortality second only to cancer. Intensive research in these areas has resulted in the identification of homocysteine (declared the ‘marker of the millennium’) and several new markers for the diagnosis and prediction of CAD and stroke. The book is a valuable resource for clinicians and consultants in practice, as well as for postgraduate and undergraduate students of medicine, biotechnology and biochemistry.
I Gutching is a book meant for EVERY working professional and student who aspires a zestful career. The material here is especially of value to Business Leaders, Managers, Human Resource specialists, Trainers and those in the teaching field. This book will compel you to start valuing Natural Intelligence and look beyond Corporate Casteism. It will teach you how to look for Natural avenues for self-growth. Observation skills is the pivot of career success. You will create fair playgrounds for everyone and be able to transform self, teams, departments, organization and policies - making you someone who upholds a thriving environment where ALL flourish. The book is written in a style that delivers Key Concepts first and then follows it up with 7 stories to test YOUR observation skills. How Open is your 3rd eye. Are you Gutching?
This book provides an in-depth coverage on competency mapping and assessment centre and includes an extensive list of generic competencies, competency models for HR, leadership, model for future competency, automobile sector, and academic institutions and experiences of some consultancy assignments. It presents the complete know-how of developing a competency framework in detail for all practitioners and professionals. The volume examines ‘what, why, how’ on the subject and extensive support models that have been developed over years of research, consultancy, and training experience across private, public, and government sectors in India, Bangladesh, Saudi Arabia, Nepal, the UK, and other countries. The book has been designed to help scholars and practitioners to understand, develop, manage, and map competencies with their organizations. The chapters are illustrated with figures and tables, along with examples, for a better understanding. The glossary of job task analysis will be helpful in job analysis, which is one of the most important tasks in developing competency models. The volume would be useful to both the academic and corporate world. The students, researchers, and faculty of business management courses, especially those specializing in human resource management, will have an in-depth understanding of ‘What and Why’ of competency frameworks, models, and assessment centre. It will be an essential resource for corporates—public and private sectors—multinational organizations, staff training institutions, learning and development centres, consultancy firms, trainers, government and public service organizations, etc. to get a hands-on understanding of ‘How’ of developing competency framework, competency mapping and assessment centre in their organizations.
For centuries India has had Muslim rule and rulers - including female Sultans – yet, with the rise of Hindu fundamentalism, India’s Muslim history and the Muslim contribution is being obscured and downplayed. Against this background, the opportunities for Muslim women to raise their concerns over access to education rights and work opportunities, or to raise issues within Muslim personal law – including marriage, divorce and personal freedoms – are severely restricted. This new Report Muslim Women in India calls for an end to discrimination against Muslims in India and the oppression of Muslim women. The author Seema Kazi questions the way in which the rise of the Hindu right-wing has led to a tightening of the interpretations of Muslim women’s rights and freedoms, along with the subordination of Muslim women’s concerns to the demands of Muslim communal identity. This Report discusses: Muslim history in India pre- and postindependence and partition; Muslim men and women’s current position in India; Muslim women’s involvement in the wider women’s movements; and has a focus on gender, Islam and human rights. The Report concludes with an outlook for Muslims and Muslim women in India, and with a set of recommendations on some of the key issues to be addressed. Please note that the terminology in the fields of minority rights and indigenous peoples’ rights has changed over time. MRG strives to reflect these changes as well as respect the right to self-identification on the part of minorities and indigenous peoples. At the same time, after over 50 years’ work, we know that our archive is of considerable interest to activists and researchers. Therefore, we make available as much of our back catalogue as possible, while being aware that the language used may not reflect current thinking on these issues.
This book introduces some emerging functional foods that are natural resources with tremendous promise as nutraceuticals and pharmaceuticals. The author considers biodiversity and bioprospecting as a response to food security issues, drug-resistance, nutrition-poor diets and other problems, exploring the prospects of several under-utilized nutrients and bioactive repositories. Readers will discover biochemical makeups, validated health benefits, explanations of underlying mechanisms, hurdles in the path of popularity and promotion strategies. Chapters explore particular plants, seeds and fruits including the strawberry guava, opuntia fruits, the Carissa genus, grape seeds, quinoa and the milk thistle (Silybum), amongst others. They are considered as food sources where possible and from the perspective of the roles they can play in complementary and alternative medicine, such as in wound healing, antimicrobial activity, gastroprotective activity in treatment of cancers and as natural antioxidant sources. This rich compilation holds plausible solutions to a range of current issues and it endorses the much-needed goal of sustainability in terms of diet and drugs. It paves the path for further research and development on hitherto obscure natural resources. Scientists working in the area of food development, phytochemical and antioxidant analysis, bioprospecting of low-profile foods and in complementary and alternative medicine will find this work particularly valuable. It will also be of interest to the general reader with an interest in food science, food security, phytochemicals and functional food studies.
Knowledge Whizz (Revised Editi on), is a unique series that aims to off er general knowledge covering a wide range of subjects, both curricular as well as extra-curricular. These are GK books for learning, not quiz books for testing.
Knowledge Whizz (Revised Editi on), is a unique series that aims to off er general knowledge covering a wide range of subjects, both curricular as well as extra-curricular. These are GK books for learning, not quiz books for testing.
Kiran takes chances. Most people in larger companies don't like making deals because, if they go wrong, they lose their career; if they go right, their superior takes the credit. You have to live in an environment where, to make a deal successful, you have to make everyone successful or [make] everyone own the failure; you have to know what the risks are and what the [chances of] success will be. In Kiran's case, she likes to make everyone around her feel successful.' Jeremy Levin, former CEO of Teva and current chairman and CEO of Ovid Therapeutics At the age of twenty-five, Kiran Mazumdar-Shaw partnered with an Irish entrepreneur, Leslie Auchincloss, to start Biocon India in a garage in Bengaluru. Armed with just a degree in beer making, this move to industrial enzymes and commodity small molecules was as audacious as it was far-sighted. Thirty-seven years on, Biocon is India's largest research-driven biotech enterprise. And the accidental entrepreneur, Mazumdar-Shaw, is today a tough negotiator and a habitual dealmaker, casually breaking several myths about Indian women in business. Without a supportive academic ecosystem for biotechnology and in the absence of sound policymaking, Mazumdar-Shaw has tirelessly sought out global alliances and resources in her quest for ideas and molecules. To some extent, she has also plugged the brain drain of Indian scientists, making them collaborators in the fight against diabetes and cancer, and creating a space for research in India. In Mythbreaker, author Seema Singh brings alive Mazumdar-Shaw's three-decade journey through a motley cast of characters -- scientists, ministries, pharma rivals, FMCG giants -- who came together to produce a narrative that is remarkable for its randomness, luck and relentless pursuit of the next scientific breakthrough.
Plant tissue culture is commonly used to describe the in-vitro and aseptic growth of any plant part on a nutrient medium. This technology is based on three fundamental objectives,1) The plant part or explants must be isolated from the rest of plant body,2) The explants must be maintained in controlled physically (environmental) and chemically designed (nutrient medium) conditions.3) Asepsis must be maintainedIt is required for asepsis to maintain a high degree of cleanliness in the laboratory, whether the techniques are being used for simple propagation, as a method to study genetic, metabolic or development charges in a model system, or for the creation of new plant variations via genetic engineering. There are a number of basic facilities and a minimum level of organization that should be available to the people working in the laboratory. The basic facility comprises of the following.
Society is obsessed with categorising and treating individuals and groups according to their physical and non-physical differences, such as sex, gender, disability and race. This treatment can lead to the inclusion or exclusion of an individual from the tangible and intangible benefits of society. Where this practice becomes discriminatory, legal frameworks can protect human rights and ensure that people are treated with due respect for their similarities and differences. In a sporting context, the inclusion and exclusion of athletes based upon their differences is often a necessary part of the essence of competitive sporting activity, arranged around rules and categories that can have an unequal exclusionary impact on certain classes of individual. Dominant sporting cultures can also have exclusionary effects. This important and innovative book seeks to investigate the socio-legal and regulatory balance between inclusion and exclusion in competitive sport. It critically analyses a range of legal and non-legal cases concerning sport-specific inclusion and exclusion in the areas of sex, gender, disability and race, including those cases involving Oscar Pistorius, Caster Semenya and Luis Suarez, to identify the extent to which the law and sport adopt a justifiable and legitimate inclusive or exclusive approach to participation. The book explores national and international regulatory frameworks, identifying deficiencies and good practice, and concludes with recommendations for regulatory reform. Inclusion and Exclusion in Competitive Sport is important reading for anybody with an interest in the relationship between sport and wider society, sports development, sport management, sports law, or socio-legal studies.
Protocols and Applications in Enzymology provides instruction on the experimental procedures of enzyme isolation techniques, innovative screening techniques, and instrument enabled enzyme assays and their underlying principles, among other protocols. The book serves as a one-stop solution for those working with different enzyme protocols in the fields of biochemistry, microbiology, biotechnology and allied subjects. Each chapter offers a full overview of protocol key resources, materials required, quantifiable and statistical analysis, optimization and troubleshooting, safety considerations, and standards. Applications are discussed across distribution and diversity of microbial enzymes, enzyme screening, enzymes in solid state fermentations, enzyme assays, enzyme kinetics, and biotechnological uses. - Provides step-by-step instruction on enzyme protocols and applications, with actionable discussions of needed resources, materials, quantification and statistical analysis, optimization and troubleshooting, safety considerations and standards - Presents easy to read, reproducible protocols for researchers and students across academia and industry - Includes color diagrams that illustrate key concepts
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