Bioinformatics, a field devoted to the interpretation and analysis of biological data using computational techniques, has evolved tremendously in recent years due to the explosive growth of biological information generated by the scientific community. Soft computing is a consortium of methodologies that work synergistically and provides, in one form or another, flexible information processing capabilities for handling real-life ambiguous situations. Several research articles dealing with the application of soft computing tools to bioinformatics have been published in the recent past; however, they are scattered in different journals, conference proceedings and technical reports, thus causing inconvenience to readers, students and researchers. This book, unique in its nature, is aimed at providing a treatise in a unified framework, with both theoretical and experimental results, describing the basic principles of soft computing and demonstrating the various ways in which they can be used for analyzing biological data in an efficient manner. Interesting research articles from eminent scientists around the world are brought together in a systematic way such that the reader will be able to understand the issues and challenges in this domain, the existing ways of tackling them, recent trends, and future directions. This book is the first of its kind to bring together two important research areas, soft computing and bioinformatics, in order to demonstrate how the tools and techniques in the former can be used for efficiently solving several problems in the latter. Sample Chapter(s). Chapter 1: Bioinformatics: Mining the Massive Data from High Throughput Genomics Experiments (160 KB). Contents: Overview: Bioinformatics: Mining the Massive Data from High Throughput Genomics Experiments (H Tang & S Kim); An Introduction to Soft Computing (A Konar & S Das); Biological Sequence and Structure Analysis: Reconstructing Phylogenies with Memetic Algorithms and Branch-and-Bound (J E Gallardo et al.); Classification of RNA Sequences with Support Vector Machines (J T L Wang & X Wu); Beyond String Algorithms: Protein Sequence Analysis Using Wavelet Transforms (A Krishnan & K-B Li); Filtering Protein Surface Motifs Using Negative Instances of Active Sites Candidates (N L Shrestha & T Ohkawa); Distill: A Machine Learning Approach to Ab Initio Protein Structure Prediction (G Pollastri et al.); In Silico Design of Ligands Using Properties of Target Active Sites (S Bandyopadhyay et al.); Gene Expression and Microarray Data Analysis: Inferring Regulations in a Genomic Network from Gene Expression Profiles (N Noman & H Iba); A Reliable Classification of Gene Clusters for Cancer Samples Using a Hybrid Multi-Objective Evolutionary Procedure (K Deb et al.); Feature Selection for Cancer Classification Using Ant Colony Optimization and Support Vector Machines (A Gupta et al.); Sophisticated Methods for Cancer Classification Using Microarray Data (S-B Cho & H-S Park); Multiobjective Evolutionary Approach to Fuzzy Clustering of Microarray Data (A Mukhopadhyay et al.). Readership: Graduate students and researchers in computer science, bioinformatics, computational and molecular biology, artificial intelligence, data mining, machine learning, electrical engineering, system science; researchers in pharmaceutical industries.
This book discusses the politics of space and identity in the borderlands of northeastern India between the early 1800s and the 1930s. Critiquing contemporary post-colonial histories where this region emerges as fragments, this book sees these perspectives as continuing to be entrapped in a civilizational approach to history writing. Beginning in the pre-colonial period where it focuses on the negotiated character of state-formation during the Mughal imperium, the book then enters the space of the colonial where it looks at some of the early interventions of the East India Company. The analysis of markets as transmitters of authority highlights an important argument that the book makes. Peasantization and the introduction of the notion of the sedentary agriculturist as the productive subject also come up for a detailed discussion, along with economic change and property settlements, which are seen as important ways through which the institution of colonial legality got entrenched in the region. Underlining the interface between the political economy and practices of cultural studies, the book also explores the connections between speech, production of counter narratives of historical memory, political culture and economy, with a focus on the cultural production of a borderland identity that was marked by hyphenated existence between proto- 'Bengal' and proto- 'Assam'.
As a comprehensive textbook in survey sampling, this book discusses the inadequacies of classic, designed-based inferential procedures and provides alternative approaches in the form of model formulations, model-design-based procedures of analysis, inference and interpretation. The book focuses on a wide range of topics which included Bayesian and Empirical Bayesian approaches, complex procedures of stratification, clustering, sampling in multi stages and phases, linear and non-linear estimation of parameters, small area estimation by spatial and chronological modelling, network and adaptive sampling methods and more. The book includes detailed case studies and exercises, making it valuable for students of statistics, specifically survey sampling.
This book analyses the impact that prolonged socio-political conflict in India has had on political and social spaces for women. Focusing in particular on Assam in the North East of India, it looks at how the conflict can be restricting, and yet can also have the potential to expand these spaces for women owing to the collapsing of boundaries of gender roles, thereby creating niche areas that may be leveraged for socio-political transformation. Based on empirical material collected from in-depth interviews with individuals on both sides of the conflict, the book locates the analysis in both a legal and political context. It examines the causes, dynamics and impact of the ethno-political conflicts in Assam, as well as the efficacy and outcomes of ‘capacity building’ programmes aimed at rehabilitating the surrendered militants as well as assisting affected women. The book goes on to look at the role played by civil society, especially the Mahila Shanti Sena (Women Peace Corp), towards conflict transformation. It highlights the preventive, mitigative and adaptive measures taken by the women and their role as agents of peace in the volatile zones of North East India. Analysing the changing role of women in conflict situations, as well as the legal measures and regulatory mechanisms in place for women in vulnerable pockets of India, this book is a useful contribution to Gender Studies, Peace and Conflict Studies, and South Asian Politics.
This book constitutes the refereed proceedings of the First International Conference on Pattern Recognition and Machine Intelligence, PReMI 2005, held in Kolkata, India in December 2005. The 108 revised papers presented together with 6 keynote talks and 14 invited papers were carefully reviewed and selected from 250 submissions. The papers are organized in topical sections on clustering, feature selection and learning, classification, neural networks and applications, fuzzy logic and applications, optimization and representation, image processing and analysis, video processing and computer vision, image retrieval and data mining, bioinformatics application, Web intelligence and genetic algorithms, as well as rough sets, case-based reasoning and knowledge discovery.
The military plays an important role in nation-building and national security. Notwithstanding special requirements of military life, the members of the armed forces should enjoy the rights guaranteed in the Constitution and other relevant international human rights treaties which India has ratified to the extent that those rights are available to other citizens of the country. The guarantee of a fair trial should apply to all proceedings under the military legal system, including summary trial and summary systems of court martial. The government must ensure the economic, social, and cultural rights of military personnel including housing, medical care, education, free legal aid and social security. Derogations of the Fundamental Rights under Article 33 should not be carried so far as to create a class of citizens who are not entitled to the benefits of the liberal interpretation of the Constitution. This book is aimed at all those who are involved in promoting, protecting, and enforcing the rights of not only the members of the armed forces, but also the other forces engaged in the security of the country. It will of relevance to parliamentarians, government officials, military authorities and members of the civil society who have a stake in the armed forces.
Based on a survey of 160 women managers from ten public sector organizations carried out between 1993 and 1996. Investigates factors affecting their career development focusing on five main variables: the sex-role orientation of these managers, leadership style, fear of success, organizational stresses and coping style. Includes a review of the literature on these issues and looks at the status of women managers in some other countries.
Would you call studying Shakespeare an exercise in futility? Or an imposition of colonialism even after the sun has sunk deep for the Britishers? Why should we wrack our brains to understand an archaic language? Why, in our post-colonial times, would we wish to know what an English dramatist of the 16th century wrote about? Well, do read his plays, despite their sometimes-archaic language, to know the answers to those questions. They have so much to tell us about the ways of men and women, of rulers and governments, of illusions and delusions, of love and war, of order and anarchy! Sounds as if I am talking about current times? You think you’re living in tempestuous times? Well, so had Shakespeare. And the times haven’t changed! Because, men and women, despite everything, haven’t changed! Don’t believe me. Find out for yourselves. Just pick up Shakespeare Then and Again: The Tempest and see this play is a mirror for us. This book is meant for Shakespearean fans as well as sceptics, students, teachers, et al. And the answers to so many questions are not blowin’ in the wind but are to be found in this play.
An invaluable tool in Bioinformatics, this unique volume provides both theoretical and experimental results, and describes basic principles of computational intelligence and pattern analysis while deepening the reader's understanding of the ways in which these principles can be used for analyzing biological data in an efficient manner. This book synthesizes current research in the integration of computational intelligence and pattern analysis techniques, either individually or in a hybridized manner. The purpose is to analyze biological data and enable extraction of more meaningful information and insight from it. Biological data for analysis include sequence data, secondary and tertiary structure data, and microarray data. These data types are complex and advanced methods are required, including the use of domain-specific knowledge for reducing search space, dealing with uncertainty, partial truth and imprecision, efficient linear and/or sub-linear scalability, incremental approaches to knowledge discovery, and increased level and intelligence of interactivity with human experts and decision makers Chapters authored by leading researchers in CI in biology informatics. Covers highly relevant topics: rational drug design; analysis of microRNAs and their involvement in human diseases. Supplementary material included: program code and relevant data sets correspond to chapters.
In response to the rise in chronic medical conditions--and the growing use of complementary and alternative therapies--among pediatric and adolescent patients, healthcare practitioners are taking a serious look at pediatric integrative medicine (PIM). Although it dovetails with current concepts of preventive medicine, wellness, and patient control, PIM is still an evolving field with its own particular challenges and opportunities. A Guide to Integrative Pediatrics for the Healthcare Professional explores its subject through the more familiar lens of integrative medicine. This concise comprehensive resource synthesizes the knowledge base on a range of therapies commonly associated with PIM, such as acupuncture, herbal remedies, clinical hypnosis, yoga, homeopathy, and therapeutic massage, with findings on their effective use with children. Case examples illustrate uses of PIM modalities with allopathic medicine to treat young patients at various developmental stages, and the authors pinpoint safety and appropriateness concerns, answer licensing questions, and note clinical areas requiring further study. The wide-ranging information contained here will help support interest in PIM at the research, training, and practice levels. Features of the Guide: An introduction to basic concepts in PIM. Trends in IM/PIM education. A survey of complementary and alternative therapies, including biologically-based, body-based, mind-body, energy-based, and alternative whole systems. Current evidence for IM in treating common pediatric conditions. The future of integrative pediatrics. References and links for further information. Offering a front-row seat to the continued expansion of the field, A Guide to Integrative Pediatrics for the Healthcare Professional is a salient text not only for pediatricians but for all healthcare practitioners tasked with improving children's wellbeing. “/p>
This book provides a unified framework that describes how genetic learning can be used to design pattern recognition and learning systems. It examines how a search technique, the genetic algorithm, can be used for pattern classification mainly through approximating decision boundaries. Coverage also demonstrates the effectiveness of the genetic classifiers vis-à-vis several widely used classifiers, including neural networks.
When Mehula begins to see a stranger invade her privacy, it sets off a chain of events that brings her estranged husband Sanjay back into her life. But gradually matters spiral out of control as she starts losing her perspective. Their teenage daughter Sona refuses to get bogged down by the turn of events and unwittingly inspires her father to re-evaluate their lives and look forward to the future with renewed hope. Meanwhile, living in the same city, Mehula’s childhood friend Priya is fighting her own demons. Repeatedly raped by her music teacher when she was a teenager, Priya tries to draw solace in her job as a sports instructor at a reputed school in Mumbai. But a visit to her childhood city Kolkata on a professional assignment forces her to confront her violent past in a manner that pushes her once again into a deep abyss – but deliverance comes from the most unexpected quarter. Set against the backdrop of a rapidly changing society, Hard Rains examines issues of companionship, disenchantment, retribution, reconciliation and loss – making it both universal and topical.
Clustering is an important unsupervised classification technique where data points are grouped such that points that are similar in some sense belong to the same cluster. Cluster analysis is a complex problem as a variety of similarity and dissimilarity measures exist in the literature. This is the first book focused on clustering with a particular emphasis on symmetry-based measures of similarity and metaheuristic approaches. The aim is to find a suitable grouping of the input data set so that some criteria are optimized, and using this the authors frame the clustering problem as an optimization one where the objectives to be optimized may represent different characteristics such as compactness, symmetrical compactness, separation between clusters, or connectivity within a cluster. They explain the techniques in detail and outline many detailed applications in data mining, remote sensing and brain imaging, gene expression data analysis, and face detection. The book will be useful to graduate students and researchers in computer science, electrical engineering, system science, and information technology, both as a text and as a reference book. It will also be useful to researchers and practitioners in industry working on pattern recognition, data mining, soft computing, metaheuristics, bioinformatics, remote sensing, and brain imaging.
When Mehula begins to see a stranger invade her privacy, it sets off a chain of events that brings her estranged husband Sanjay back into her life. But gradually matters spiral out of control as she starts losing her perspective. Their teenage daughter Sona refuses to get bogged down by the turn of events and unwittingly inspires her father to re-evaluate their lives and look forward to the future with renewed hope. Meanwhile, living in the same city, Mehula’s childhood friend Priya is fighting her own demons. Repeatedly raped by her music teacher when she was a teenager, Priya tries to draw solace in her job as a sports instructor at a reputed school in Mumbai. But a visit to her childhood city Kolkata on a professional assignment forces her to confront her violent past in a manner that pushes her once again into a deep abyss – but deliverance comes from the most unexpected quarter. Set against the backdrop of a rapidly changing society, Hard Rains examines issues of companionship, disenchantment, retribution, reconciliation and loss – making it both universal and topical.
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