Sandra Amberg's Books

Stand Up! Deliver

By: Sandra Amberg

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Stand Up! Deliver By: Sandra Amberg The Sisters of St. Francis on the Hill in historic Dubuque, Iowa, are working very hard to maintain their large holdings and dwindling population. Sustainability is their goal. In the forefront of the action is Sister Margaret Sorenson, age 92, whose motto “STAND UP! DELIVER” will not allow her to pass by a problem or opportunity without acting. In STAND UP! DELIVER, Sister Margaret encounters people in need whose skills and talents she is able to utilize at the convent, to everyone’s benefit. Meet the beautiful Gypsy Vanner horses and the three-year-old who can read their minds; a librarian who was raped and went into hiding; a divorced woman who only wants to farm and realize her dreams; a young couple in love who are unable to have children of their own; a history teacher writing curriculum to show the importance of horses in all aspects of life; a social worker discovering her father is a rapist; and a young boy with exceptional artistic talent and a drug-addicted mother. Like Ebru art, marbling oil on water, Sister Margaret introduces the players to each other, and with a lot of imagination, work, and prayer, she blends them to form heavenly patterns.

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Page Count

270

Publisher

Dorrance Publishing

Published Date

ISBN 10

1480990396

ISBN 13

9781480990395

Structure-based Design of Drugs and Other Bioactive Molecules

Tools and Strategies

By: Arun K. Ghosh,Sandra Gemma

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Structure-based Design of Drugs and Other Bioactive Molecules

Tools and Strategies

By: Arun K. Ghosh,Sandra Gemma

Drug design is a complex, challenging and innovative research area. Structure-based molecular design has transformed the drug discovery approach in modern medicine. Traditionally, focus has been placed on computational, structural or synthetic methods only in isolation. This one-of-akind guide integrates all three skill sets for a complete picture of contemporary structure-based design. This practical approach provides the tools to develop a high-affinity ligand with drug-like properties for a given drug target for which a high-resolution structure exists. The authors use numerous examples of recently developed drugs to present "best practice" methods in structurebased drug design with both newcomers and practicing researchers in mind. By way of a carefully balanced mix of theoretical background and case studies from medicinal chemistry applications, readers will quickly and efficiently master the basic skills of successful drug design. This book is aimed at new and active medicinal chemists, biochemists, pharmacologists, natural product chemists and those working in drug discovery in the pharmaceutical industry. It is highly recommended as a desk reference to guide students in medicinal and chemical sciences as well as to aid researchers engaged in drug design today.

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