Choosing Web 2.0 Tools for Learning and Teaching in a Digital World provides practical strategies and examples to effectively integrate Web 2.0 tools to support the inquiry process in the school library program and the classroom curriculum. Targeted for school librarians, this book addresses the questions: What is digital literacy? How is learning different in a digital world? And the most important questions, what are the best strategies, resources, and tools to support effective teaching and learning in a digital environment? The first two chapters of the book provide the important context for school librarians: research on student learning behaviors in a digital environment, Web 2.0 background and characteristics, and alignment with the new AASL Standards for the Twenty-first Century Learner and the Stripling Inquiry Process. Grades 4-12.
Sally Cornelison draws upon contemporary visual, literary, and archival sources and diverse methodologies to interpret how the persona of St. Antoninus and the intercessory effectiveness of his relic cult were advertised to a broad audience of viewers and devotees during the Renaissance. Tracing the history of St. Antoninus' burial sites from 1459 until 1589, this interdisciplinary study demonstrates that the saint's cult was a key element of Florence's sacred cityscape.
Describes nineteen different bird families with advice on ways to attract each family with nesting sights, shrub cover, and a variety of specific plant suggestions.
Since precolonial times, agriculture has been deeply woven into the fabric of Pennsylvania's history and culture. Pennsylvania Farming presents the first history of Pennsylvania agriculture in more than sixty years, and offers a completely new perspective. Sally McMurry goes beyond a strictly economic approach and considers the diverse forces that helped shape the farming landscape, from physical factors to cultural repertoires to labor systems. Above all, the people who created and worked on Pennsylvania's farms are placed at the center of attention. More than 150 photographs inform the interpretation, which offers a sweeping look at the evolution of Pennsylvania's agricultural landscapes right up to the present day.
Loss of biodiversity is among the greatest problems facing the world today. Conservation and the Genetics of Populations gives a comprehensive overview of the essential background, concepts, and tools needed to understand how genetic information can be used to conserve species threatened with extinction, and to manage species of ecological or commercial importance. New molecular techniques, statistical methods, and computer programs, genetic principles, and methods are becoming increasingly useful in the conservation of biological diversity. Using a balance of data and theory, coupled with basic and applied research examples, this book examines genetic and phenotypic variation in natural populations, the principles and mechanisms of evolutionary change, the interpretation of genetic data from natural populations, and how these can be applied to conservation. The book includes examples from plants, animals, and microbes in wild and captive populations. This second edition contains new chapters on Climate Change and Exploited Populations as well as new sections on genomics, genetic monitoring, emerging diseases, metagenomics, and more. One-third of the references in this edition were published after the first edition. Each of the 22 chapters and the statistical appendix have a Guest Box written by an expert in that particular topic (including James Crow, Louis Bernatchez, Loren Rieseberg, Rick Shine, and Lisette Waits). This book is essential for advanced undergraduate and graduate students of conservation genetics, natural resource management, and conservation biology, as well as professional conservation biologists working for wildlife and habitat management agencies. Additional resources for this book can be found at: www.wiley.com/go/allendorf/populations.
Oxophytodienoic acid reductases (OPRs) are flavoenzymes closely related to Old Yellow Enzyme (OYE) from Saccharomyces. The physiological role of plant OPRs could only be clarified for OPR3: OPR3 from tomato and Arabidopsis reduce the double bond of the α,β-unsaturated carbonyl group of (9S,13S)-oxophytodienoic acid (OPDA), the precursor of the phytohormone jasmonic acid (JA). OPR3 is therefore an important step for JA biosynthesis and the following JA-triggered defensive and developmental adaptations of the plant. Since the production of phytohormones, including JA, is regulated in an extremely time- and tissue specific manner, the regulatory step of JA-biosynthesis was sought. The conversion of OPDA by OPR3 was proposed as the rate-limiting step in biosynthesis as OPR3 turned out to form a self-inhibiting dimer when crystallized. In the OPR3 crystal, the L6-loop from each protomer reaches into the active site cavity of the other protomer. The dimerization-dependent block of the active site provides a hypothetical mechanism for the regulation of OPR3 activity. Interestingly, two sulfate ions were enclosed in the interacting site of the protomers, suggesting that the dimer might be stabilized in vivo by reversible sulfation or phosphorylation of the tyrosine 364(SlOPR3) or 365 (AtOPR3), respectively. The role of this hypothesized sulfation/phosphorylation was subject of this study. Neither sulfation nor phosphorylation of Y365 could be detected by mass spectrometry. Hence, studies were continued with an in vitro approach where OPR3 was expressed with sulfotyrosine incorporated co-translationally at position 365 (Y365SY). Biochemical characterization led to contradictory results: On the one hand, interaction strength of Y365SY was unaltered in comparison to wild-type OPR3, while on the other hand, activity of Y365SY was reduced. Closer examination indicated that substrate binding or product release was reduced in Y365SY. These changes could be traced back to the additional charge of the SO42—ion, which leads to a narrowing of the entrance to the active site cavity. With this finding, the proposed regulating mechanism by sulfation/phosphorylation is still valid, but independent from dimerization. In order to link this potential regulatory mechanism with a post-translational modification in vivo, an untargeted screen was performed, in which OPR3 was expressed as a fusion protein with a promiscous biotin ligase (BioID2). With this method, potentially interacting proteins were biotinylated in vivo and subsequently isolated and analyzed by MS/MS. Many candidate proteins were identified for OPR3, including kinases and phosphatases. Additionally, OPR1, OPR2 and OPR4 from Arabidopsis were also expressed as BioID2 fusion proteins in order to clarify their physiological role. The most promising results were obtained for OPR4, which was found to be association with stress granule and P-body proteins.
This is the first book in English to provide a comprehensive examination of the hospital movement that arose and prospered in northern Italy between the twelfth and fifteenth centuries. Throughout this flourishing urbanised area hundreds of independent semi-religious facilities appeared, offering care for the ill, the poor and pilgrims en route to holy sites in Rome and the eastern Mediterranean. Over three centuries they became mechanisms for the appropriation of civic authority and political influence in the communities they served, and created innovative experiments in healthcare and poor relief which are the precursors to modern social welfare systems. Will appeal to students and lecturers in medieval, social, religious, and urban history and includes a detailed appendix that will assist researchers in the field.
The relentless loss of biodiversity is among the greatest problems facing the world today. The third edition of this established textbook provides an updated and comprehensive overview of the essential background, concepts, and tools required to understand how genetics can be used to conserve species, reduce threat of extinction, and manage species of ecological or commercial importance. This edition is thoroughly revised to reflect the major contribution of genomics to conservation of populations and species. It includes two new chapters: "Genetic Monitoring" and a final "Conservation Genetics in Practice" chapter that addresses the role of science and policy in conservation genetics. New genomic techniques and statistical analyses are crucial tools for the conservation geneticist. This accessible and authoritative textbook provides an essential toolkit grounded in population genetics theory, coupled with basic and applied research examples from plants, animals, and microbes. The book examines genetic and phenotypic variation in natural populations, the principles and mechanisms of evolutionary change, evolutionary response to anthropogenic change, and applications in conservation and management. Conservation and the Genomics of Populations helps demystify genetics and genomics for conservation practitioners and early career scientists, so that population genetic theory and new genomic data can help raise the bar in conserving biodiversity in the most critical 20 year period in the history of life on Earth. It is aimed at a global market of applied population geneticists, conservation practitioners, and natural resource managers working for wildlife and habitat management agencies. It will be of particular relevance and use to upper undergraduate and graduate students taking courses in conservation biology, conservation genetics, and wildlife management.
The ultimate reference resource for successful Christian writers, The Christian Writers' Market Guide 2002 includes listings of over 1,200 markets for books, articles, stories, poetry, and greeting cards. Topical listings tell writers which magazine and book publishers are interested in various topics, while additional sections provide market analysis, lists of literary agents, editorial services, writers' conferences and groups, writing contests, writing resources, and much more.
This 1998 version of this well-known reference tool for Christian writers points them to over 1000 markets for their work, provides e-mail addresses, gives dates and venues of conferences, and informs about editorial services, agents, and much more.
Choosing Web 2.0 Tools for Learning and Teaching in a Digital World provides practical strategies and examples to effectively integrate Web 2.0 tools to support the inquiry process in the school library program and the classroom curriculum. Targeted for school librarians, this book addresses the questions: What is digital literacy? How is learning different in a digital world? And the most important questions, what are the best strategies, resources, and tools to support effective teaching and learning in a digital environment? The first two chapters of the book provide the important context for school librarians: research on student learning behaviors in a digital environment, Web 2.0 background and characteristics, and alignment with the new AASL Standards for the Twenty-first Century Learner and the Stripling Inquiry Process. Grades 4-12.
Glorious East End saga from the author of SALT OF THE EARTH A nostalgic saga set in Cheshire which continues the story of Becky Taylor - the gutsy heroine introduced in SALT OF THE EARTH - and her family as they struggle against the odds to find happiness.
When a box of toys is left, abandoned in the park, the toys really don't know what to make of it! Should they wait to be rescued and taken back to the 'land of lounge' or should they all scramble out and try to save themselves. Fortunately for them they are saved from making a decision with the intervention of two very nice mice. But the night is young, and their adventures are only about to begin. A touching book featuring the adventures and exploits of a mismatched group of friends who learn to live in harmony.
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