In the fall of 1980, Genentech, Inc., a little-known California genetic engineering company, became the overnight darling of Wall Street, raising over $38 million in its initial public stock offering. Lacking marketed products or substantial profit, the firm nonetheless saw its share price escalate from $35 to $89 in the first few minutes of trading, at that point the largest gain in stock market history. Coming at a time of economic recession and declining technological competitiveness in the United States, the event provoked banner headlines and ignited a period of speculative frenzy over biotechnology as a revolutionary means for creating new and better kinds of pharmaceuticals, untold profit, and a possible solution to national economic malaise. Drawing from an unparalleled collection of interviews with early biotech players, Sally Smith Hughes offers the first book-length history of this pioneering company, depicting Genentech’s improbable creation, precarious youth, and ascent to immense prosperity. Hughes provides intimate portraits of the people significant to Genentech’s science and business, including cofounders Herbert Boyer and Robert Swanson, and in doing so sheds new light on how personality affects the growth of science. By placing Genentech’s founders, followers, opponents, victims, and beneficiaries in context, Hughes also demonstrates how science interacts with commercial and legal interests and university research, and with government regulation, venture capital, and commercial profits. Integrating the scientific, the corporate, the contextual, and the personal, Genentech tells the story of biotechnology as it is not often told, as a risky and improbable entrepreneurial venture that had to overcome a number of powerful forces working against it.
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A delight from start to finish' SUNDAY TIMES 'A triumph of ingenuity' DAILY MAIL 'I loved it! ... A whiff of Shardlake and a pinch of Rumpole ... a joy' S.J. BENNETT, author of THE WINDSOR KNOT When barrister Gabriel Ward steps out of his rooms at exactly two minutes to seven on a sunny May morning in 1901, his mind is so full of his latest case – the disputed authorship of bestselling children's book Millie the Temple Church Mouse – that he scarcely registers the body of the Lord Chief Justice of England on his doorstep. But even he cannot fail to notice the judge's dusty bare feet, in shocking contrast to his flawless evening dress, nor the silver carving knife sticking out of his chest. In the shaded courtyards and ancient buildings of the Inner Temple, the hidden heart of London's legal world, murder has spent centuries confined firmly to the casebooks. Until now... The police can enter the Temple only by consent, so who better to investigate this tragic breach of law and order than a man who prizes both above all things? But murder doesn't answer to logic or reasoned argument, and Gabriel soon discovers that the Temple's heavy oak doors are hiding more surprising secrets than he'd ever imagined... Gabriel Ward will return in A CASE OF LIFE AND LIMB - available to pre-order now! 'A cunning and delightful mystery with rich, wonderful characters and period detail so vivid, you can touch it' IAN MOORE, author of DEATH AND CROISSANTS 'Sir Gabriel Ward KC is endearingly eccentric. Intriguing, engaging, and thoroughly satisfying' T.E. KINSEY, author of A QUIET LIFE IN THE COUNTRY 'A total delight! ... Intelligent, insightful mystery ... all skilfully woven together with a poignant, human story. I devoured it in one sitting!' SARAH YARWOOD-LOVETT, author of A MURDER OF CROWS
This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work. This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.
In the fall of 1980, Genentech, Inc., a little-known California genetic engineering company, became the overnight darling of Wall Street, raising over $38 million in its initial public stock offering. Lacking marketed products or substantial profit, the firm nonetheless saw its share price escalate from $35 to $89 in the first few minutes of trading, at that point the largest gain in stock market history. Coming at a time of economic recession and declining technological competitiveness in the United States, the event provoked banner headlines and ignited a period of speculative frenzy over biotechnology as a revolutionary means for creating new and better kinds of pharmaceuticals, untold profit, and a possible solution to national economic malaise. Drawing from an unparalleled collection of interviews with early biotech players, Sally Smith Hughes offers the first book-length history of this pioneering company, depicting Genentech’s improbable creation, precarious youth, and ascent to immense prosperity. Hughes provides intimate portraits of the people significant to Genentech’s science and business, including cofounders Herbert Boyer and Robert Swanson, and in doing so sheds new light on how personality affects the growth of science. By placing Genentech’s founders, followers, opponents, victims, and beneficiaries in context, Hughes also demonstrates how science interacts with commercial and legal interests and university research, and with government regulation, venture capital, and commercial profits. Integrating the scientific, the corporate, the contextual, and the personal, Genentech tells the story of biotechnology as it is not often told, as a risky and improbable entrepreneurial venture that had to overcome a number of powerful forces working against it.
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