Sally Exon's Books

Domesday

Book of Judgement

By: Sally Harvey

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Domesday: Book of Judgement provides a unique study of the extraordinary eleventh-century survey, the Domesday Book. Sally Harvey depicts the Domesday Book as the written evidence of a potentially insecure conquest successfully transforming itself, by a combination of administrative insight and military might, into a permanent establishment. William I used the Domesday Inquiry to contain the new establishment and consolidate their landholding revolution within a strict fiscal and tenurial framework, with checks and balances to prevent the king's followers from taking more powers and assets than they had been allocated. In this way, the survey served as a conciliatory gesture between the conquerors and the conquered, as William I came to realise that, faced with the threat to his rule from the Danes, he needed England's native populations more than they needed him. Yes, the overlying theme of the Domesday Book is Judgment: every class of society had reason to regard the Survey's methodical and often pitiless proceedings as both a literal and a metaphorical day of account. In this volume, Sally Harvey considers the Anglo-Saxon background and the architects of the survey: the bishops, royal clerks, sheriffs, jurors, and landholders who contributed to Domesday's content and scope. She also discusses at length the core information in the Survey: coinage, revenues from landholding, fiscal concessions, and taxation, as well as some central tenurial issues. She draws the conclusion that the record, whilst consolidating William's position as king of the English, also laid the foundations for the twelfth-century treasury and exchequer. The volume newly argues that the Domesday survey also became an inquest into individual sheriffs and officials, thereby laying a foundation for reinterpreting the size of towns in England.

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358

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OUP Oxford

Published Date

ISBN 10

0191648558

ISBN 13

9780191648557

Oxford Handbook of Genetics

By: Guy Bradley-Smith,Sally Hope,Helen V. Firth,Jane A. Hurst

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Oxford Handbook of Genetics

By: Guy Bradley-Smith,Sally Hope,Helen V. Firth,Jane A. Hurst

The Oxford Handbook of Genetics provides an essential overview of this complex subject, distilled into an accessible format for primary care practitioners and junior doctors. It can be used as an aide memoire to gain advice on dealing with individual patients during the working day, or as a reference text to be read over time. Combining the expertise of leading geneticists with the knowledge of experienced general practitioners, the handbook covers the genetics core curriculum as defined by the Royal College of General Practitioners. It includes sections on elementary genetics, single gene disorders, and chromosomal problems, as well as information about the multifactorial diseases, such as ischaemic heart disease, with which practitioners are more familiar. There are also comprehensive sections on antenatal issues, and cancers. A comprehensive glossary with explanations of genetic terminology, and an extensive list of resources, make this book suitable for all healthcare professionals regardless of their level of knowledge or experience. Designed to cross the primary-secondary care interface, this unique handbook covers the gap between general health training and genetic specialist training, including specific advice about when, and how, to make a referral to a genetics service. Given the rapid growth in the genetic knowledge base, this book is designed to be both accessible and informative as a substantive educational resource for practitioners.

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486

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OUP Oxford

Published Date

ISBN 10

0191039659

ISBN 13

9780191039652

Conservation and the Genomics of Populations

By: Fred W. Allendorf,W. Chris Funk,Sally N. Aitken,Margaret Byrne,Gordon Luikart

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Conservation and the Genomics of Populations

By: Fred W. Allendorf,W. Chris Funk,Sally N. Aitken,Margaret Byrne,Gordon Luikart

The relentless loss of biodiversity is among the greatest problems facing the world today. The third edition of this established textbook provides an updated and comprehensive overview of the essential background, concepts, and tools required to understand how genetics can be used to conservespecies, reduce threat of extinction, and manage species of ecological or commercial importance. This edition is thoroughly revised to reflect the major contribution of genomics to conservation of populations and species. It includes two new chapters: "Genetic Monitoring" and a final "ConservationGenetics in Practice" chapter that addresses the role of science and policy in conservation genetics.New genomic techniques and statistical analyses are crucial tools for the conservation geneticist. This accessible and authoritative textbook provides an essential toolkit grounded in population genetics theory, coupled with basic and applied research examples from plants, animals, and microbes. Thebook examines genetic and phenotypic variation in natural populations, the principles and mechanisms of evolutionary change, evolutionary response to anthropogenic change, and applications in conservation and management.Conservation and the Genomics of Populations helps demystify genetics and genomics for conservation practitioners and early career scientists, so that population genetic theory and new genomic data can help raise the bar in conserving biodiversity in the most critical 20 year period in the historyof life on Earth. It is aimed at a global market of applied population geneticists, conservation practitioners, and natural resource managers working for wildlife and habitat management agencies. It will be of particular relevance and use to upper undergraduate and graduate students taking coursesin conservation biology, conservation genetics, and wildlife management.

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785

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Oxford University Press

Published Date

ISBN 10

0198856563

ISBN 13

9780198856566

Conservation and the Genetics of Populations

By: Fred W. Allendorf,Gordon H. Luikart,Sally N. Aitken

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Conservation and the Genetics of Populations

By: Fred W. Allendorf,Gordon H. Luikart,Sally N. Aitken

Loss of biodiversity is among the greatest problems facing the world today. Conservation and the Genetics of Populations gives a comprehensive overview of the essential background, concepts, and tools needed to understand how genetic information can be used to conserve species threatened with extinction, and to manage species of ecological or commercial importance. New molecular techniques, statistical methods, and computer programs, genetic principles, and methods are becoming increasingly useful in the conservation of biological diversity. Using a balance of data and theory, coupled with basic and applied research examples, this book examines genetic and phenotypic variation in natural populations, the principles and mechanisms of evolutionary change, the interpretation of genetic data from natural populations, and how these can be applied to conservation. The book includes examples from plants, animals, and microbes in wild and captive populations. This second edition contains new chapters on Climate Change and Exploited Populations as well as new sections on genomics, genetic monitoring, emerging diseases, metagenomics, and more. One-third of the references in this edition were published after the first edition. Each of the 22 chapters and the statistical appendix have a Guest Box written by an expert in that particular topic (including James Crow, Louis Bernatchez, Loren Rieseberg, Rick Shine, and Lisette Waits). This book is essential for advanced undergraduate and graduate students of conservation genetics, natural resource management, and conservation biology, as well as professional conservation biologists working for wildlife and habitat management agencies. Additional resources for this book can be found at: www.wiley.com/go/allendorf/populations.

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636

Publisher

John Wiley & Sons

Published Date

ISBN 10

1118408578

ISBN 13

9781118408575

Clinical Calculations - E-Book

With Applications to General and Specialty Areas

By: Joyce LeFever Kee,Sally M. Marshall,Mary Catherine Forrester,Kathryn Woods

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Clinical Calculations - E-Book

With Applications to General and Specialty Areas

By: Joyce LeFever Kee,Sally M. Marshall,Mary Catherine Forrester,Kathryn Woods

- NEW! Updated information on Antidiabetic Agents (orals and injectables) has been added throughout the text where appropriate. - NEW! Updated content on Anticoagulant Agents is housed in an all-new chapter. - NEW! Colorized abbreviations for the four methods of calculation (BF, RP, FE, and DA) appear in the Example Problems sections. - NEW! Updated content and patient safety guidelines throughout the text reflects the latest practices and procedures. - NEW! Updated practice problems across the text incorporate the latest drugs and dosages.

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4094

Publisher

Elsevier Health Sciences

Published Date

ISBN 10

0323674224

ISBN 13

9780323674225

Ghost Walls

The Story of a 17th-Century Colonial Homestead

By: Sally M. Walker

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Ghost Walls

The Story of a 17th-Century Colonial Homestead

By: Sally M. Walker

In 1638, John Lewger made a home in the wilderness of the New World, in a place called Maryland. He named his house St. John's, and for nearly eighty years, it was the center of an ambitious English plan to build a new kind of community on American soil. Men and women lived and worked within its walls. Babies were born. Last breaths drawn. St. John's walls witnessed the first stirrings of the great struggles that would dominate the continent for the next three centuries: The unimaginable wealth of the New World's crops and natural resources. The promise of religious tolerance under a new model of government. The injustice of slavery. The betrayal of native peoples. The struggle for equality between men and women. If St. John's walls could have talked, they would have spoken volumes of American history. And then the walls crumbled. One hundred years after it was built, St. John's House had been abandoned. The buildings slowly deteriorated, returning to the Maryland soil to be plowed under by generations of Maryland farmers. St. John's walls were silent for more than two centuries, little more than ghosts haunting the historical and archeological records. But they weren't lost. Not entirely. Award-winning author Sally M. Walker tells the story of how teams of scientists and historians managed to hear the ghostly echoes of St. John's House and, over the course of decades of painstaking work, made them speak their stories again.

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140

Publisher

Carolrhoda Books

Published Date

ISBN 10

1467746258

ISBN 13

9781467746250

Medieval English Benedictine Liturgy

Studies in the Formation, Structure, and Content of the Monastic Votive Office, c. 950-1540

By: Sally Elizabeth (Roper) Harper

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Medieval English Benedictine Liturgy

Studies in the Formation, Structure, and Content of the Monastic Votive Office, c. 950-1540

By: Sally Elizabeth (Roper) Harper

Originally published in 1993, Medieval English Benedictine Liturgy is a detailed study of the liturgical use of medieval monasteries in England, spanning 500 years. The study examines the major votive observances that came to fruition in the twelfth century and later and argues that these important practices affected earlier monastic observances. The book’s emphasis on Anglo-Saxon liturgy provides a bridge between the practices of the English Benedictines before and after the Conquest. The book also traces the chronological progress of three individual observances and extends where possible into the sixteenth century. The book argues that, at a broader level, while liturgy has been recognized as an indispensable part of the study of the context and use of medieval chant and polyphony.

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375

Publisher

Routledge

Published Date

ISBN 10

0429513712

ISBN 13

9780429513718

Engendering the Subject

Gender and Self-Representation in Contemporary Women's Fiction

By: Sally Robinson

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Engendering the Subject

Gender and Self-Representation in Contemporary Women's Fiction

By: Sally Robinson

Robinson sets up a dialogue between feminist critical theory and contemporary women's fiction in order to argue for a new way of reading the specificity of women's writing. Through theoretically informed readings of novels by Doris Lessing, Angela Carter, and Gayl Jones, the author argues that female subjectivity is engendered in discourse through the woman writer's strategic engagement in representational systems that rely on a singular figure of Woman for coherence. Through this engagement, women's self-representation emerges as a process through which women take up multiple and contradictory positions in relation to different hegemonic discursive systems, and through which they engender themselves as subjects. Finally, Engendering the Subject suggests how women's fiction can provide a model for a feminist practice of reading that would simultaneously work against the historical containment of Woman, and for the empowerment of women as subjects of cultural practices.

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270

Publisher

State University of New York Press

Published Date

ISBN 10

1438417551

ISBN 13

9781438417554

Quantitative Bioimaging

An Introduction to Biology, Instrumentation, Experiments, and Data Analysis for Scientists and Engineers

By: Raimund J. Ober,E. Sally Ward,Jerry Chao

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Quantitative Bioimaging

An Introduction to Biology, Instrumentation, Experiments, and Data Analysis for Scientists and Engineers

By: Raimund J. Ober,E. Sally Ward,Jerry Chao

Quantitative bioimaging is a broad interdisciplinary field that exploits tools from biology, chemistry, optics, and statistical data analysis for the design and implementation of investigations of biological processes. Instead of adopting the traditional approach of focusing on just one of the component disciplines, this textbook provides a unique introduction to quantitative bioimaging that presents all of the disciplines in an integrated manner. The wide range of topics covered include basic concepts in molecular and cellular biology, relevant aspects of antibody technology, instrumentation and experimental design in fluorescence microscopy, introductory geometrical optics and diffraction theory, and parameter estimation and information theory for the analysis of stochastic data. Key Features: Comprises four parts, the first of which provides an overview of the topics that are developed from fundamental principles to more advanced levels in the other parts. Presents in the second part an in-depth introduction to the relevant background in molecular and cellular biology and in physical chemistry, which should be particularly useful for students without a formal background in these subjects. Provides in the third part a detailed treatment of microscopy techniques and optics, again starting from basic principles. Introduces in the fourth part modern statistical approaches to the determination of parameters of interest from microscopy data, in particular data generated by single molecule microscopy experiments. Uses two topics related to protein trafficking (transferrin trafficking and FcRn-mediated antibody trafficking) throughout the text to motivate and illustrate microscopy techniques. An online appendix providing the background and derivations for various mathematical results presented or used in the text is available at http://www.routledge.com/9781138598980.

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693

Publisher

CRC Press

Published Date

ISBN 10

0429892128

ISBN 13

9780429892127

Essie's Story

The Life and Legacy of a Shoshone Teacher

By: Esther Burnett Horne,Sally McBeth

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Essie's Story

The Life and Legacy of a Shoshone Teacher

By: Esther Burnett Horne,Sally McBeth

First Bison Books printing: 1999"--T.p. verso.

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276

Publisher

U of Nebraska Press

Published Date

ISBN 10

080327324X

ISBN 13

9780803273245

Getting Justice and Getting Even

Legal Consciousness Among Working-Class Americans

By: Sally Engle Merry

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Getting Justice and Getting Even

Legal Consciousness Among Working-Class Americans

By: Sally Engle Merry

Ordinary Americans often bring family and neighborhood problems to court, seeking justice or revenge. The litigants in these local squabbles encounter law at its boundaries in the corridors of busy city courthouses, in the offices of court clerks, and in the church parlors used by mediation programs. Getting Justice and Getting Even concerns the legal consciousness of working class Americans and their experiences with court and mediation. Following cases into and through the courts, Sally Engle Merry provides an ethnographic study of local law and of the people who use it in a New England city. The litigants, primarily white, native-born, and working class, go to court because as part of mainstream America they feel entitled to use its legal system. Although neither powerful nor highly educated, they expect the law's support when they face intolerable infringements of their rights, privacy, and safety. Yet as personal problems enter the legal system and move through mediation sessions, clerk's hearings, and prosecutor's conferences, the citizen plaintiff rapidly loses control of the process. Court officials and mediators interpret and characterize the meaning of these experiences, reframing and categorizing them in different discourses. Some plaintiffs yield to these interpretations, but others resist, struggling to assert their own version of the problem. Ultimately, Merry exposes the paradox of legal entitlement. While going to court allows an individual to dominate domestic relationships, the litigant must increasingly yield control of the situation to the court that supplies that power.

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238

Publisher

University of Chicago Press

Published Date

ISBN 10

0226520692

ISBN 13

9780226520698

Music in Welsh Culture Before 1650

A Study of the Principal Sources

By: Sally Harper

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Music in Welsh Culture Before 1650

A Study of the Principal Sources

By: Sally Harper

Music in Wales has long been a neglected area. Scholars have been deterred both by the need for a knowledge of the Welsh language, and by the fact that an oral tradition in Wales persisted far later than in other parts of Britain, resulting in a limited number of sources with conventional notation. Sally Harper provides the first serious study of Welsh music before 1650 and draws on a wide range of sources in Welsh, Latin and English to illuminate early musical practice. This book challenges and refutes two widely held assumptions - that music in Wales before 1650 is impoverished and elusive, and that the extant sources are too obscure and fragmentary to warrant serious study. Harper demonstrates that there is a far wider body of source material than is generally realized, comprising liturgical manuscripts, archival materials, chronicles and retrospective histories, inventories of pieces and players, vernacular poetry and treatises. This book examines three principal areas: the unique tradition of cerdd dant (literally 'the music of the string') for harp and crwth; the Latin liturgy in Wales and its embellishment, and 'Anglicised' sacred and secular materials from c.1580, which show Welsh music mirroring English practice. Taken together, the primary material presented in this book bears witness to a flourishing and distinctive musical tradition of considerable cultural significance, aspects of which have an important impact on wider musical practice beyond Wales.

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517

Publisher

Routledge

Published Date

ISBN 10

1351557254

ISBN 13

9781351557252

Post-translational modification and regulation of oxophytodienoate reductase 3 (OPR3) (Band 14)

By: Sally Victoria Weiss

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Post-translational modification and regulation of oxophytodienoate reductase 3 (OPR3) (Band 14)

By: Sally Victoria Weiss

Oxophytodienoic acid reductases (OPRs) are flavoenzymes closely related to Old Yellow Enzyme (OYE) from Saccharomyces. The physiological role of plant OPRs could only be clarified for OPR3: OPR3 from tomato and Arabidopsis reduce the double bond of the α,β-unsaturated carbonyl group of (9S,13S)-oxophytodienoic acid (OPDA), the precursor of the phytohormone jasmonic acid (JA). OPR3 is therefore an important step for JA biosynthesis and the following JA-triggered defensive and developmental adaptations of the plant. Since the production of phytohormones, including JA, is regulated in an extremely time- and tissue specific manner, the regulatory step of JA-biosynthesis was sought. The conversion of OPDA by OPR3 was proposed as the rate-limiting step in biosynthesis as OPR3 turned out to form a self-inhibiting dimer when crystallized. In the OPR3 crystal, the L6-loop from each protomer reaches into the active site cavity of the other protomer. The dimerization-dependent block of the active site provides a hypothetical mechanism for the regulation of OPR3 activity. Interestingly, two sulfate ions were enclosed in the interacting site of the protomers, suggesting that the dimer might be stabilized in vivo by reversible sulfation or phosphorylation of the tyrosine 364(SlOPR3) or 365 (AtOPR3), respectively. The role of this hypothesized sulfation/phosphorylation was subject of this study. Neither sulfation nor phosphorylation of Y365 could be detected by mass spectrometry. Hence, studies were continued with an in vitro approach where OPR3 was expressed with sulfotyrosine incorporated co-translationally at position 365 (Y365SY). Biochemical characterization led to contradictory results: On the one hand, interaction strength of Y365SY was unaltered in comparison to wild-type OPR3, while on the other hand, activity of Y365SY was reduced. Closer examination indicated that substrate binding or product release was reduced in Y365SY. These changes could be traced back to the additional charge of the SO42—ion, which leads to a narrowing of the entrance to the active site cavity. With this finding, the proposed regulating mechanism by sulfation/phosphorylation is still valid, but independent from dimerization. In order to link this potential regulatory mechanism with a post-translational modification in vivo, an untargeted screen was performed, in which OPR3 was expressed as a fusion protein with a promiscous biotin ligase (BioID2). With this method, potentially interacting proteins were biotinylated in vivo and subsequently isolated and analyzed by MS/MS. Many candidate proteins were identified for OPR3, including kinases and phosphatases. Additionally, OPR1, OPR2 and OPR4 from Arabidopsis were also expressed as BioID2 fusion proteins in order to clarify their physiological role. The most promising results were obtained for OPR4, which was found to be association with stress granule and P-body proteins.

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265

Publisher

Cuvillier Verlag

Published Date

ISBN 10

3736966873

ISBN 13

9783736966871

Unto a Good Land

A History of the American People

By: David Edwin Harrell,John B. Boles,Sally Foreman Griffith

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Unto a Good Land

A History of the American People

By: David Edwin Harrell,John B. Boles,Sally Foreman Griffith

Unto a Good Land offers a distinctive narrative history of the American people -- from the first contacts between Europeans and North America's native inhabitants, through the creation of a modern nation, to the standing of the United States as a world power. Written by a team of distinguished historians led by David Edwin Harrell, Jr. and Edwin S. Gaustad, this textbook shows how grasping the uniqueness of the bAmerican experimentb depends on understanding the role of religion as well as social, cultural, political, and economic factors in shaping U.S. history. A common shortcoming of most United States history textbooks is that while, in recent decades, they have expanded their coverage of social and cultural history, they still tend to shortchange the role of religious ideas, practices, and movements in the American past. "Unto a Good Land addresses this shortcoming in a balanced way. The authors recognize that religion is only one of many factors that have influenced our past -- one, however, that has often been neglected in textbook accounts. This volume gives religion its appropriate place in the story. "Unprecedented coverage of the forces that have shaped the history of the United States While none of America's rich history is left out, this volume is the first U.S. history textbook to give serious attention to the religious dimension of American life. This textbook is not a religious history; instead, it offers an account of American history that includes religious ideas, practices, and movements whenever they played a shaping role. "Comprehensive and current This volume traces the American story from the earliest encounters between the first North Americaninhabitants and Europeans through the 2004 presidential election. Complete and balanced treatment is also given to issues of gender, race, and ethnicity, as well as cultural, political, and economic forces. "A clear and compelling narrative The authors are more than expert historians; they are also talented writers who recognize history to be the retelling of human life. United by a seamless narrative structure, these chapters restore the bstoryb to history. "Multiple formats specially designed for flexible classroom use "Unto a Good Land is available as a single hardcover edition or as two paperback volumes, offering maximum flexibility when adapting curriculum for one- and two-semester courses in U.S. history. The two paperback volumes can be used for U.S. history survey courses divided at 1865 or 1900 -- or at any date in between. "Informative special features to complement the text In addition to the book's exceptional narrative, an array of special features enhances the instructional value of the text and points students to resources for further study. "Includes assistance for teaching and test preparation The instructor's manual for "Unto a Good Land provides helpful suggestions for lesson plans and assignments, and the test bank provides multiple-choice and essay questions for use as study aids, quizzes, or tests. "Suitable for instruction at both secular and religious colleges and universities Drawing on their experience in both secular and religious schools, the authors have ensured that this textbook is suitable for U.S. history classes in a wide variety of settings.

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1330

Publisher

Wm. B. Eerdmans Publishing

Published Date

ISBN 10

0802837182

ISBN 13

9780802837189

Clinical Management of Thyroid Disease E-Book

By: Fredric E. Wondisford,Sally Radovick

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Clinical Management of Thyroid Disease E-Book

By: Fredric E. Wondisford,Sally Radovick

Clinical Management of Thyroid Disease is an exciting new book edited by Fredric Wondisford, MD—developer of the revolutionary new drug, Thyrotropin—and Sally Radovick, MD, with contributions from experts in the field. It fulfills the niche of a succinct, clinical resource to help you translate research into practice. This full-color volume offers valuable information on thyroid cancer and non-cancerous lesions, the effect of drugs on thyroid function, genetic disorders, and more in an accessible, easy-to-read consistent format. Presents the expertise of authors and editorial staff comprised of leaders in the field of thyroid research and clinical management for the best-qualified guidance on diagnosis and treatment. Provides a full-color, comprehensive approach that makes valuable information easy to locate and quick to read. Covers relevant topics applicable to all levels of training and expertise to serve as a detailed clinical reference on everything from the basic to the sophisticated. Captures research advances on hot topics such as thyroid cancer and non-cancerous lesions, the effect of drugs on thyroid function, and genetic disorders so that you can incorporate them into the way you treat patients.

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Page Count

435

Publisher

Elsevier Health Sciences

Published Date

ISBN 10

1437719694

ISBN 13

9781437719697

Textbook of Blood Banking and Transfusion Medicine

By: Sally V. Rudmann

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Textbook of Blood Banking and Transfusion Medicine

By: Sally V. Rudmann

This comprehensive book on transfusion practices and immunohematology offers concise, thorough guidelines on the best ways to screen donors, store blood components, ensure safety, anticipate the potentially adverse affects of blood transfusion, and more. It begins with the basics of genetics and immunology, and then progresses to the technical aspects of blood banking and transfusion. Chapters are divided into sections on: Basic Science Review; Blood Group Serology; Donation, Preparation, and Storage; Pretransfusion Testing; Transfusion Therapy; Clinical Considerations; and Safety, Quality Assurance, and Data Management. Developed specifically for medical technologists, blood bank specialists, and residents, the new edition conforms to the most current standards of the American Association of Blood Banks (AABB). Expert Opinion essays, written by well-known, frequently published experts, discuss interesting topics of research or new advances in the field. Important terms are defined in the margins of the pages on which they appear, enabling readers to easily check the meaning of an unfamiliar term where it appears in context. Margin notes highlight important concepts and points, remind readers of previously discussed topics, offer an alternative perspective, or refer readers to other sources for further information. Material conforms to the most recent AABB standards for the most accurate, up-to-date information on immunohematology. Advanced concepts, beyond what is required for entry-level practice, are set apart from the rest of the text so readers can easily differentiate between basic and advanced information. A new chapter on Hematopoietic Stem Cells and Cellular Therapy (chapter 19) provides cutting-edge coverage of cellular therapy and its relevance to blood-banking. New content has been added on molecular genetics, component therapy, and International Society of Blood Transfusion (ISBT) nomenclature, as well as the latest information on HIV, hepatitis, quality assurance, and information systems. Coverage of new technologies, such as nucleic acid technology and gel technology, keeps readers current with advances in the field.

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