Being a systematic treatment of the modern theory of stochastic integrals and stochastic differential equations, the theory is developed within the martingale framework, which was developed by J.L. Doob and which plays an indispensable role in the modern theory of stochastic analysis.A considerable number of corrections and improvements have been made for the second edition of this classic work. In particular, major and substantial changes are in Chapter III and Chapter V where the sections treating excursions of Brownian Motion and the Malliavin Calculus have been expanded and refined. Sections discussing complex (conformal) martingales and Kahler diffusions have been added.
Increasing knowledge and information about the relationship between food and health have led to new insights into the effects of physiologically functional food factors on reducing the risk of life style-related diseases. These insights have contributed to the development of functional food science as a partner of existing nutritional and food sciences. This partner is already a matter of global concern, coming to occupy a central position of bioscience and bioindustry in many countries of the world. The main theme of the conference was Food factors: physiologic functions and disease risk reduction with comprised a variety of subthemes: Nutrigenomics, Mineral functions, Carbohydrate functions, Functional proteins and peptides, Probiotics and immunology, Oxidative stress and biomarkers, Cancer prevention, Antioxidative factors, Functional foods and FOSHU, Anti-inflammation and anti-infection, Calorie and health, Food safety and epidemiology, Food technology and industry for health.
Japan's technology support system has played a crucial role in developing firms technological capability and stimulating their innovation. How has it been done, and why is it effective? The research findings presented here show that what has worked best in Japan is inter-firm cooperative learning, which requires the support of public technology institutions to promote cooperation, disseminate technology, and facilitate innovation. Among the many books published about Japanese technology policies and corporate management, this is the first to show definitively that cooperative learning is important in a wide spectrum of firms, whether or not they are keiretsu-affiliated. With a caveat on the limitations of the Japanese system from an institutional perspective, the countrys techno-governance structure is revealed to be more effective in assembly-oriented industries than in those that are basic-science oriented and employ rapidly changing technology.
Bald nach Erscheinen des Bandes "Geschwülste" "Geschwiilste" 1956 1956 wurde wurde deutlich, deutlich, daß daB dies dies nur ein Anfang gewesen sein konnte. Die grundlegenden Beitrage Beiträge dieses Bandes spiegelten den Wissensstand am Beginn des 6. Jahrzehnts wider. Sie waren wahrscheinlich zugleich die letzten echten Handbuchbeitrage Handbuchbeiträge zu diesem Thema: umfassend und enzyklopadisch enzyklopädisch vollständig vollstandig und trotzdem als Ganzes lesbar, verfaßt verfaBt von den damals besten Sachkennern in Deutschland. Inzwischen hat sich das Handbuch der Allgemeinen Pathologie gewandelt. Entsprechend der Weitung des Faches vergrößerten vergroBerten sich die Themen. Neben den Bänden Banden tiber über die die Organe Organe zum zum Hilfsmechanismus Hilfsmechanismus des des Stoffwechsels, Stoffwechsels, tiber über die die Zelle, Zelle, das das Altern Altern usw. usw. nahm sich der Geschwulstband vergleichsweise bescheiden aus. Das steht im Gegensatz zur Stellung des Geschwulstproblems in der Allgemeinen Pathologie. Die Krebsforschung erfuhr gerade in den letzten beiden Jahrzehnten einen vorher nicht geahnten Aufschwung, so daß daB eine eine enzyklopädische enzyklopadische Zusammenfassung Zusammenfassung heute heute den den Umfang Umfang des des gesamten gesamten Handbuches Handbuches einnehmen einnehmen würde wtirde -- wenn wenn sich sich jemand fände, rande, das das zu zu versuchen. versuchen. Und wenn der letzte Band gedruckt wäre, ware, ware wäre der erste hoffnungslos veraltet.
Annotation "Horizons in Cancer Research" presents original research results on the leading edge of cancer. Each article has been carefully selected in an attempt to present substantial research results across a broad spectrum. This book presents the latest research in the field of cancer research, including a global overview on cancer biology; increased risk of cancer with exposure to chemical pollutants; organotin-containing polyethers as anticancer drugs; and stem cell and gene therapy as potential treatment applications.
This book presents original research results on the leading edge of cancer. Topics discussed include the etiology and treatment of gallbladder cancer; HPV vaccine and cervical cancer; docetaxel therapy and applications; metastatic cancer pain management for the bone, spine and liver; the effects of cytoskeletal structure change induced by docetaxel on gene expression; nutrition and breast cancer; and docetaxel's effect on ovarian function and in the management of patients with head and neck squamous cell carcinoma.
This book presents original results on the leading edge of cancer research. Topics discussed include oral cancer cachexia; the immunological mechanisms of cachexia; research in gynecologic oncology today; advances in cellular understanding of muscle wasting in cachexia; and next generation sequencing developments in cancer research by bioinformatics approaches.
Progression of colorectal cancer (CRC) is a main cause of its morbidity and mortality. CRC progression is characterized by increased growth of the primary carcinoma as well as lymphatic and haematogenic spread. The microenvironment of primary or circulating and disseminated tumor cells seems to be essential in all steps of the metastatic process of CRC. Therefore, the authors suggest that cancer-associated cellular stroma evolving from the extracellular matrix should be crucially integrated with CRC diagnosis, staging and treatment.Following this, a short review focuses on the immunohistochemical findings and the molecular signaling pathways during the development from chronic inflammation to Kaposi's sarcoma formation. Kaposi's sarcoma is a multifocal neoplasm characterized by deregulated neoangiogenesis, proliferation of spindle cells with infiltrated inflammatory cells and erythrocytes in the skin and visceral organs.The papillary thyroid carcinoma from tall cells (tall cell variant, TCV) was first described by Hawk and Hazard in 1976. 162 such cases were published in the world literature prior to 2000. This is a rare tumor with a frequency of 1-2 cases per million people in Europe and the US. Taking into account the histological pattern, immunophenotype and the results of molecular genetic research, additional differential diagnostic criteria for papillary thyroid cancer from tall cells with transformation into anaplastic carcinoma have been proposed.Cervical cancer is mainly caused by infection with high-risk types of human papillomavirus (HPV), especially type 16. In this collection, the authors present a study which reveals that HPV16E6 protein induces COX-2 gene and protein expression through PI3K/Akt signaling pathway in association with the increase of PGE2-EP4 receptor leading to promote carcinogenesis.False positive and false negative diagnoses in focal carcinomas of the prostate represents one of the most common and significant problems in daily practice. Thus, the authors conclude with a summary of the criteria of greatest value to establish the diagnosis of carcinoma when only some neoplastic glands are found. These focal adenocarcinomas have been termed limited, minimal, minimal volume carcinoma and microcarcinomas. Although most are unique, they may occasionally be found in other sites on the same biopsy, in subsequent biopsies, or in prostatectomy products.
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