Microneedles can be used for delivery of a wide range of drug substances for practically any medical condition and present a real opportunity for vaccines and medicines that are unsuitable for oral administration or conventional patch delivery. Microneedle-mediated Transdermal and Intradermal Drug Delivery covers the major aspects relating to the use of microneedle arrays in enhancing drug delivery applications. It provides an overview of the various methods employed to design and produce microneedles, from the different materials involved to the importance of application methods. It carefully and critically reviews ongoing transdermal and intradermal delivery research using microneedles and includes the outcomes of in vivo animal and human studies. Importantly, it also discusses the safety and patient acceptability studies carried out to date. Finally, the book reviews the recent patents in microneedle research and describes the ongoing developments within industry that will determine the future of microneedle-mediated transdermal and intradermal drug delivery. By an expert author team with practical experience in the design and development of drug delivery systems this is the only text that provides a comprehensive review of microneedle research in transdermal and intradermal drug delivery.
The contemporary philosopher William Desmond has many companions in thought, and one of the most important of these is Augustine. In lucid prose that draws on the riches of a vibrant philosophical-theological tradition, Renée Köhler-Ryan explores Desmond’s metaxological philosophy. She brings together philosophy, theology and literature to elaborate on the conversation that Desmond’s philosophical work in discovering how humans are constantly ‘between’ sustains with a tradition of thinkers that also includes Plato, Thomas Aquinas and Shakespeare. Whether considering how our elemental wonder at creation brings us closer to God, or how our most intimate revelations about being human happen in the interior space of prayer, reading Desmond with Augustine illuminates a porous and interdisciplinary space of inquiry. With a foreword from Desmond himself, Companions in the Between is a unique contribution to the growing body of scholarship on his thought. Köhler-Ryan’s analysis will entice any reader who wants to know more about how contemporary philosophy can contest a space where philosophers are formulaically expected to shy away from divine transcendence.
Access all of the latest advances in imaging techniques of the retina and posterior segment on your favorite eReader with Ryan's Retinal Imaging and Diagnostics eBook. 12 chapters from the landmark reference Retina, 5th Edition offer the foundations to better understand, apply, and optimize new and emerging retinal imaging technologies. Examine and evaluate the newest diagnostic technologies and approaches that are changing the management of retinal disease, including future imaging technologies which will soon become the standard. Put the very latest diagnostic imaging methods to work in your practice, including optical coherence tomography (OCT), fluoroscein angiography, indocyanine angiography autofluorescence imaging, ophthalmic ultrasound and more. Benefit from the extensive knowledge and experience of esteemed editor and ophthalmologist, the late Dr. Stephen Ryan, and a truly global perspective from the world authorities. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Compatible with Kindle®, nook®, and other popular devices.
Unequalled in scope, depth, and clinical precision, Retina, 5th Edition keeps you at the forefront of today's new technologies, surgical approaches, and diagnostic and therapeutic options for retinal diseases and disorders. Comprehensively updated to reflect everything you need to know regarding retinal diagnosis, treatment, development, structure, function, and pathophysiology, this monumental ophthalmology reference work equips you with expert answers to virtually any question you may face in practice. Benefit from the extensive knowledge and experience of esteemed editor Dr. Stephen Ryan, five expert co-editors, and a truly global perspective from 358 other world authorities across Europe, Asia, Australasia the Americas.Examine and evaluate the newest diagnostic technologies and approaches that are changing the management of retinal disease, including future technologies which will soon become the standard.Put the very latest scientific and genetic discoveries, diagnostic imaging methods, drug therapies, treatment recommendations, and surgical techniques to work in your practice.
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