This book focuses on the fundamentals of the use of biologics in asthma, describing the rationale, principles, mechanisms of action, and indications. It offers an excellent balance between basic science and the analysis of clinical trials, updating readers with new developments that are changing the global scenario for targeted biological anti-asthma therapies, especially with regard to more severe disease. A range of therapies are considered, from the humanized monoclonal anti-IgE antibody omalizumab, widely approved as add-on treatment for inadequately controlled disease, through to emerging biologics for which evidence supportive of efficacy is accumulating, including anti-IL-5, anti-IL-4, and anti-IL-13 therapies. One aspect to emerge is the variability in individual response, which suggests a need for characterization of different asthma subtypes to permit the effective implementation of phenotype-targeted treatments. This book will be of interest for pulmonologists, clinical immunologists, and physicians seeking sound information on these therapies, but also for scientists and pharmacologists wishing to enhance their knowledge of the therapeutic implications of the cellular and molecular mechanisms that underlie severe, uncontrolled asthma.
A Prosopography to Martial’s Epigrams is the first dictionary of all the characters and personal names found in the work of Marcus Valerius Martialis, containing nearly 1,000 comprehensive entries. Each of them compiles and analyses all the relevant information regarding the characters themselves, as well as the literary implications of their presence in Martial’s poems. Unlike other works of this kind, the book encompasses not only real people, whose positive existence is beyond doubt, but also fictional characters invented by the poet or inherited from the cultural and literary tradition. Its entries provide the passages of the epigrams where the respective characters appear; the general category to which they belong; the full name (in the case of historical characters); onomastic information, especially about frequency, meaning, and etymology; other literary or epigraphical sources; a prosopographical sketch; a discussion of relevant manuscript variants; and a bibliography. Much attention is paid to the literary portrayal of each character and the poetic usages of their names. This reference work is a much needed tool and is intended as a stimulus for further research.
L'attenzione avvolge di senso ogni cosa.L'attenzione disvela la bellezza racchiusa nello scrigno segreto dell'essenza.L'attenzione permette di fare merletti con i fili penduli dei brandelli di realtà che ci circondano.L'attenzione decripta codici che da millenari arcani governano il mondo.L'attenzione è richiesta al degustatore quando incontra un nettare divino.....
L'attenzione avvolge di senso ogni cosa.L'attenzione disvela la bellezza racchiusa nello scrigno segreto dell'essenza.L'attenzione permette di fare merletti con i fili penduli dei brandelli di realtà che ci circondano.L'attenzione decripta codici che da millenari arcani governano il mondo.L'attenzione è richiesta al degustatore quando incontra un nettare divino.....
L'attenzione avvolge di senso ogni cosa.L'attenzione disvela la bellezza racchiusa nello scrigno segreto dell'essenza.L'attenzione permette di fare merletti con i fili penduli dei brandelli di realtà che ci circondano.L'attenzione decripta codici che da millenari arcani governano il mondo.L'attenzione è richiesta al degustatore quando incontra un nettare divino.....
This book focuses on the fundamentals of the use of biologics in asthma, describing the rationale, principles, mechanisms of action, and indications. It offers an excellent balance between basic science and the analysis of clinical trials, updating readers with new developments that are changing the global scenario for targeted biological anti-asthma therapies, especially with regard to more severe disease. A range of therapies are considered, from the humanized monoclonal anti-IgE antibody omalizumab, widely approved as add-on treatment for inadequately controlled disease, through to emerging biologics for which evidence supportive of efficacy is accumulating, including anti-IL-5, anti-IL-4, and anti-IL-13 therapies. One aspect to emerge is the variability in individual response, which suggests a need for characterization of different asthma subtypes to permit the effective implementation of phenotype-targeted treatments. This book will be of interest for pulmonologists, clinical immunologists, and physicians seeking sound information on these therapies, but also for scientists and pharmacologists wishing to enhance their knowledge of the therapeutic implications of the cellular and molecular mechanisms that underlie severe, uncontrolled asthma.
This will help us customize your experience to showcase the most relevant content to your age group
Please select from below
Login
Not registered?
Sign up
Already registered?
Success – Your message will goes here
We'd love to hear from you!
Thank you for visiting our website. Would you like to provide feedback on how we could improve your experience?
This site does not use any third party cookies with one exception — it uses cookies from Google to deliver its services and to analyze traffic.Learn More.