A handbook for navigating our troubled and precarious times intended to help readers imagine and make their world anew. In search of new knowledge practices that can help us make the world livable again, this book takes the reader on a journey across time—from the deep past to the unfolding future. The authors search beyond human knowledge to establish negotiated partnerships with forms of knowledge within the planet itself, examining how we have manipulated these historically through an anthropocentric focus. The book explores the many different kinds of knowledge, and the diversity of instruments needed to invoke and actuate the potency of human and nonhuman agencies. Four key phases in our ways of knowing are identified: material, strengthening, reconfiguring and extending, which are exemplified through case studies that take the form of worlding experiments. This pioneering work will inspire architects, artists and designers as well as students, teachers and researchers across arts and design disciplines.
Computational Mechanics of the Classical Guitar describes a new dynamic paradigm in instrument acoustics based on time-dependent transient analysis and simulation of complete musical instruments. It describes the current state of theoretical and experimental research into the guitar for engineers, instrument makers and musicians. This includes a summary of the basic equations for the mechanics of vibrating bodies and a presentation of the FDM (finite difference method) model with which the true vibrational behaviour of the instrument as an entire system can be understood for the first time. This monograph presents various new theoretical and experimental results and insights into guitar playing such as the coupling between the strings and the top plate or a description of the finger noise made when the fingers slide over the strings before plucking.
That science-fiction future in which technology would make everything very good—or very bad—has not yet arrived. From our vantage point at least, no age appears to have had a deeper faith in the inevitability and imminence of such a total technological transformation than the early twentieth century. Russia was no exception."—from the introduction In the Soviet Union, it seems, armoring oneself against the world did not suffice—it was best to become metal itself. In his engaging and accessible book, Rolf Hellebust explores the aesthetic and ideological function of the metallization of the revolutionary body as revealed in Soviet literature, art, and politics. His book shows how the significance of this modern myth goes far beyond the immediate issue of the enthusiasm with which the Bolsheviks welcomed such a symbolic transfiguration and that of our own uneasy attraction to the images of metal flesh and machine-men. Hellebust's literary examples range from the famous (Pasternak's Doctor Zhivago) to the forgotten (early Soviet proletarian poets). To these he adds a mix of non-Russian references, from creation myths to comic book superheroes, medieval alchemy to Moby-Dick. He includes readings of posters, sculpture, and political discourse as well as cross-cultural comparisons to revolutionary France, industrial-age America, and Nazi Germany. The result is a fascinating portrait of the ultimate symbols of dehumanizing modernity, as refracted through the prism of utopian humanism.
This book constitutes the refereed proceedings of the 10th Annual European Symposium on Algorithms, ESA 2002, held in Rome, Italy, in September 2002. The 74 revised full papers presented were carefully reviewed and selected from a total of 201 submissions. The papers address all current issues in Algorithmics, in particular computational biology, computational finance, computational geometry, databases and information retrieval, external memory algorithms, graph and network algorithms, graph drawing, algorithmic learning, network design, online algorithms, parallel and distributed computing, pattern matching, data compression, quantum computing, randomized algorithms, and symbolic computation.
Precise dynamic models of processes are required for many applications, ranging from control engineering to the natural sciences and economics. Frequently, such precise models cannot be derived using theoretical considerations alone. Therefore, they must be determined experimentally. This book treats the determination of dynamic models based on measurements taken at the process, which is known as system identification or process identification. Both offline and online methods are presented, i.e. methods that post-process the measured data as well as methods that provide models during the measurement. The book is theory-oriented and application-oriented and most methods covered have been used successfully in practical applications for many different processes. Illustrative examples in this book with real measured data range from hydraulic and electric actuators up to combustion engines. Real experimental data is also provided on the Springer webpage, allowing readers to gather their first experience with the methods presented in this book. Among others, the book covers the following subjects: determination of the non-parametric frequency response, (fast) Fourier transform, correlation analysis, parameter estimation with a focus on the method of Least Squares and modifications, identification of time-variant processes, identification in closed-loop, identification of continuous time processes, and subspace methods. Some methods for nonlinear system identification are also considered, such as the Extended Kalman filter and neural networks. The different methods are compared by using a real three-mass oscillator process, a model of a drive train. For many identification methods, hints for the practical implementation and application are provided. The book is intended to meet the needs of students and practicing engineers working in research and development, design and manufacturing.
This book provides a state-of-the-art assessment on a variety of biofiltration water treatment systems from studies conducted around the world. The authors collectively represent a perspective from 23 countries and include academics/researchers, biofiltration system users, designers, and manufacturers. Progress in Slow Sand and Alternative Biofiltration Processes - Further Developments and Applications offers technical information and discussion to provide perspective on the biological and physical factors affecting the performance of slow sand filtration and biological filtration processes. Chapters were submitted from the 5th International Slow Sand and Alternative Biological Filtration Conference, Nagoya, Japan in June 2014. Authors: Nobutada Nakamoto, Shinshu University, Japan, Nigel Graham, Imperial College London, UK, M. Robin Collins, University of New Hampshire, Durham, NH, USA and Rolf Gimbel,Universität Duisburg, Essen, Germany.
Between 1980 and 1996 the number of arrests has increased considerably for offenders ages 12 and under. This increase is a cost to society in two ways: the cost of the crime and the cost of multiple agencies involved with these children. Several questions have developed due to this increase: How does the juvenile justice system deal with child delinquents? Is child delinquency a predictor of serious, violent, and chronic offending? How early can we predict, and what are early warning signs? In an effort to develop answers for these questions and many more, editors Rolf Loeber and David Farrington organized a study group on Very Young offenders comprising 39 experts on juvenile delinquency and child problem behavior. Over a two-year period of intense and collaborative work these individuals have produced the book Child Delinquents: Development, Intervention, and Service Needs. Presenting empirically derived insights, Child Delinquents is the definitive statement to date on the working knowledge of prevalence, development, risk and protective factors, and optimal intervention with preteen offenders. This book is an excellent source for a broad audience of researchers, scholars, psychiatry, and practitioners at the administrative level.
The first decade of the new century proved to be a deadly one for many children and young people in the United States. Despite increased policing on the streets, higher rates of incarceration, harsher sentencing, stricter control of illegal drugs, and attempts to reduce access to firearms, FBI reports show that more than 7,300 young people between the ages of 15 and 29 were murdered in 2008 alone. It’s clear that traditional crime reduction strategies have not stemmed the rising tide of homicides perpetrated by and upon one of society’s most vulnerable populations. Innovative, practicable solutions are needed to staunch this lethal trend. Based on the findings of a unique longitudinal study, Young Homicide Offenders and Victims: Risk Factors, Prediction, and Prevention from Childhood now provides experts with unprecedented analysis of prospectively collected data on 1,517 boys and young men who grew up in Pittsburgh, Pennsylvania. Following these males from childhood into early adulthood, examining their lives and the conditions under which they grew up in a representative mid-sized American city, the study forms the basis of this unique volume designed to stimulate debate on key questions of prevention and intervention as well as dispel popular myths about the childhood and adolescent features of homicide offenders and homicide victims. Key areas of coverage include: Early childhood risk factors of young homicide offenders and victims. Insights into homicide offenders’ lives as told in their own words. The effectiveness of screening for at-risk youth. Risk factor–based prevention and intervention strategies. The impact of interventions on homicide rates. Policy implications at the local, state, and national levels. Young Homicide Offenders and Victims: Risk Factors, Prediction, and Prevention from Childhood is essential reading for researchers, practitioners, and policy makers across the fields of juvenile justice and criminology, developmental psychology, sociology, psychiatry, public health, and policy making. ------- “This book changes the game in violence research ... The analysis is masterful, the prose is readable, and the achievement is nothing short of stunning.” Richard Rosenfeld, Ph.D. / Curators Professor of Criminology and Criminal Justice, University of Missouri-St. Louis “This book will stand the test of time as a landmark homicide study.” James C. Howell, Ph.D. / Senior Research Associate, National Gang Center “This is a fascinating, pioneering book ... The authors’ sophisticated analyses demonstrate convincingly the considerable value of prospective longitudinal data for enhancing our understanding of the etiology and control of lethal violence.” Steven F. Messner, Ph.D. / Distinguished Teacher Professor, Department of Sociology, University at Albany, SUNY / President, American Society of Criminology
This two-volume work in biblical studies is a commemorative presentation to Simon John DeVries, noted Old Testament Scholar. Volume one offers a series of essays on issues in Hebrew bible studies. The topics addressed include the nature of Yahweh as God of Israel, a reexamination of the Exodus tradition, the Priestly code and practices, prophets and revelation, biblical poetry, issues in biblical linguistics, dramatic narrative in Hebrew Bible tradition and Yahweh's deliverance as redemption in Israel.
This Element is a study of how the power of imagination is, according to Kant, supposed to contribute to cognition. It is meant to be an immanent and a reconstructive endeavor, relying solely on Kant's own resources when he tries to determine what material, faculties, and operations are necessary for cognition of objects. The main discourse is divided into two sections. The first deals with Kant's views concerning the power of imagination as outlined in the A- and B- edition of the Critique of Pure Reason. The second focuses on the power of imagination in the first part of the Critique of Judgment.
Die europäische Romantik war nicht nur heterogen und intern zerstritten. Sie hatte sich auch gegen Aufklärung und Klassizismus zu verteidigen, welche um die Zeit der Französischen Revolution weiterlebten. Klassizisten betrachteten die Romantik als Anhäufung abtrünniger »neuer Schulen«, die das Monopol der Classical Tradition bedrohten. Die erbitterten Debatten in Ästhetik und Politik wurden auf beiden Seiten mit den überkommenen Strategien der klassischen »ars disputandi« geführt. Unter schwerstem satirischem Beschuss begann die Romantik, sich als eine Bewegung zu begreifen, und es entstand der problematische Gegensatz von »klassisch« und »romantisch«. Diese Konstruktion war aber unverzichtbar, um die Fronten im Wirrwarr der Stimmen zu klären, und blieb es auch in der Literatur- und Kulturwissenschaft, die auf solche Subsumptionen nicht verzichten kann. Die Classical Tradition, die das Christentum einschließt, erweist sich als ein laufender Prozess von der Antike bis heute.
While there has been great progress in the development of plant breeding over the last decade, the selection of suitable plants for human consumption began over 13,000 years ago. Since the Neolithic era, the cultivation of plants has progressed in Asia Minor, Asia, Europe, and ancient America, each specific to the locally wild plants as well as the ecological and social conditions. A handy reference for knowing our past, understanding the present, and creating the future, this book provides a comprehensive treatment of the development of crop improvement methods over the centuries. It features an extensive historical treatment of development, including influential individuals in the field, plant cultivation in various regions, techniques used in the Old World, and cropping in ancient America. The advances of scientific plant breeding in the twentieth century is extensively explored, including efficient selection methods, hybrid breeding, induced polyploidy, mutation research, biotechnology, and genetic manipulation. Finally, this book presents information on approaches to the sustainability of breeding and to cope with climatic changes as well as the growing world population.
A comprehensive history of German society in this period, providing a broad survey of its development. The volume is thematically organized and designed to give easy access to the major topics and issues of the Bismarkian and Wilhelmine eras. The statistical appendix contains a wide range of social, economic and political data. Written with the English-speaking student in mind, this book is likely to become a widely used text for this period, incorporating as it does twenty years of further research on the German Empire since the appearance of Hans-Ulrich Wehler's classic work.
Business schools are critical players in higher education, educating current and future leaders to make a difference in the world. Yet we know surprisingly little about the leaders of business schools. Leading a Business School demystifies this complex and dynamic role, offering international insights into deans’ dilemmas in different contexts and situations. It highlights the importance of deans creating challenging and supportive learning cultures to enhance business and management education, organizations and society more broadly. Written by renowned experts on the role of the dean, Julie Davies, Howard Thomas, Eric Cornuel and Rolf D. Cremer, the book traces the historical evolution of the business school deanship, the current challenges and future sources of disruption. The leadership characteristics and styles of business school deans are presented based on an examination of different dimensions of their roles. These include issues of strategic positioning, such as financial viability, prestige, size, mission, age, location and programme portfolios, as well as the influences of rankings, sector accreditations, governance structures, networks and national policies on strategy implementation. Drawing on international case studies and deans’ development programmes globally, the authors explore constraints on deans’ autonomy, university and external relations, and how business school deans add value over the period of their tenures. This candid and well-researched book is essential reading for aspiring business school leaders, those hiring and working with deans, and other higher education leaders. The Open Access version of this book, available at http://www.taylorfrancis.com, has been made available under a Creative Commons Attribution-Non Commercial-No Derivatives (CC-BY-NC-ND) 4.0 license. Funded by EFMD Global.
As the Afrika Korps withdrew after a bruising defeat at El Alamein, it became apparent that Axis forces would not be able to maintain their hold over Libya. Rommel pulled his troops back to Tunisia, digging in along the Mareth Line, and turned westwards t
This book surveys research results on the physical and mathematical modeling, as well as the numerical simulation of complex fluid and structural mechanical processes occurring in the human blood circulation system. Topics treated include continuum mechanical description; choice of suitable liquid and wall models; mathematical analysis of coupled models; numerical methods for flow simulation; parameter identification and model calibration; fluid-solid interaction; mathematical analysis of piping systems; particle transport in channels and pipes; artificial boundary conditions, and many more. The book was developed from lectures presented by the authors at the Oberwolfach Research Institute (MFO), in Oberwolfach-Walke, Germany, November, 2005.
This book examines the origins of Wilhelmine Germany's "Tirpitz Plan" of naval rearmament. The evolution of the Imperial Navy's strategic theories is compared with that of the French, British, and United States navies. Particular attention is given to the relationship between strategy and maritime law within the different national schools.
Australian Weevils: Volume IV covers the 11 smaller tribes of the weevil subfamily Entiminae (broad-nosed weevils), which comprises more than 100 genera and 700 described species in Australia. Around half of this fauna is covered in Volume IV, featuring keys to all the tribes, genera and described species as well as updated concepts and diagnoses of the tribes and summarising accounts of the taxonomy, nomenclature, distribution and known hostplants of all the genera and species. All the introduced species of Entiminae in Australia, most of which are regarded as agricultural or horticultural pests, are included, as are descriptions of 12 new genera and eight new species and identifications of about another 240 undescribed species. The book also includes an overview of the salient characters of the Entiminae, illustrated on 18 colour plates of diagnostic features needed for identifying these weevils, alongside a further 180 colour plates illustrating the habitus and genitalia of all the genera and of several other species and their diagnostic characters. The volume further includes an obituary and full publication list of the late Elwood C. Zimmerman as well as an updated list of recent literature on the Australian Entiminae and other weevils. The book is an essential reference work for researchers and students working with entimine weevils both in Australia and abroad. It is part of the Australian Weevils series.
This exciting resource introduces the core technologies that are used for Internet messaging. The book explains how Signal protocol, the cryptographic protocol that currently dominates the field of end to end encryption (E2EE) messaging, is implemented and addresses privacy issues related to E2EE messengers. The Signal protocol and its application in WhatsApp is explored in depth, as well as the different E2EE messengers that have been made available in the last decade are also presented, including SnapChat. It addresses the notion of self-destructing messages (as originally introduced by SnapChat) and the use of metadata to perform traffic analysis. A comprehensive treatment of the underpinnings of E2EE messengers, including Pretty Good Privacy (PGP) and OpenPGP as well as Secure/Multipurpose Internet Mail Extensions (S/MIME) is given to explain the roots and origins of secure messaging, as well as the evolutionary improvements to PGP/OpenPGP and S/MIME that have been proposed in the past. In addition to the conventional approaches to secure messaging, it explains the modern approaches messengers like Signal are based on. The book helps technical professionals to understand secure and E2EE messaging on the Internet, and to put the different approaches and solutions into perspective.
Compounds labeled with carbon-14 and tritium are indispensable tools for research in biomedical sciences, discovery and development of pharmaceuticals and agrochemicals. Preparation of Compounds Labeled with Tritium and Carbon-14 is a comprehensive, authoritative and up-to-date discussion of the strategies, synthetic approaches, reactions techniques, and resources for the preparation of compounds labeled with either of these isotopes. A large number of examples are presented for the use of isotopic sources and building blocks in the preparation of labeled target compounds, illustrating the range of possibilities for embedding isotopic labels in selected moieties of complex structures. Topics include: Formulation of synthetic strategies for preparing labeled compounds Isotope exchange methods and synthetic alternatives for preparing tritiated compounds In-depth discussion of carbon-14 building blocks and their utility in synthesis Preparation of enantiomerically pure isotopically labeled compounds Applications of biotransformations Preparation of Compounds Labeled with Tritium and Carbon-14 is an essential guide to the specialist strategies and tactics used by chemists to prepare compounds tagged with theradioactive atoms carbon-14 and tritium.
The current fascination with urban life has encouraged a growing interest in the 'Chicago School' of sociology by students of sociological history. It is generally accepted that the field research practised by the Chicago sociologists during the 1920s - the 'Golden Age of Chicago sociology' - used methods borrowed from anthropology. However, Rolf Lindner also argues convincingly that the orientation of urban research advocated by Robert Park, the key figure in the Chicago School and himself a former reporter, is ultimately indebted to the tradition of urban reportage. The Reportage of Urban Culture goes beyond a thorough reconstruction of the relationship between journalism and sociology. It shows how the figure of the city reporter at the turn of the century represents a new way of looking at life, and reflects a transformation in American culture, from rejecting variety to embracing it.
The International Colloquium on Automata, Languages and Programming (ICALP) is an annual conference series sponsored by the European Association for Theoretical Computer Science (EATCS). It is intended to cover all important areas of theoretical computer science, such as: computability, automata,formal languages, term rewriting, analysis of algorithms, computational geometry, computational complexity, symbolic and algebraic computation, cryptography, data types and data structures, theory of data bases and knowledge bases, semantics of programming languages, program specification, transformation and verification, foundations of logicprogramming, theory of logical design and layout, parallel and distributed computation, theory of concurrency, and theory of robotics. This volume contains the proceedings of ICALP 93, held at LundUniversity, Sweden, in July 1993. It includes five invited papers and 51 contributed papers selected from 151 submissions.
Public innovation is distinctive from private sector innovation by being set in a political system rather than a market. The roles of citizens and elected politicians as well as public servants and other stakeholders are frequently relevant. Public organizations can be creators, funders, orchestrators or sense-makers of innovations, which are carried out with the aim of benefitting society. This book provides a comprehensive insight into the theory and practice of public innovation using a wide range of research evidence about the processes, drivers and barriers, stakeholders and outcomes of innovation. Using the lens of public value, the book offers a stimulating discussion of how public innovation is valued and contested in current societies. Valuing Public Innovation aims to help develop a deeper understanding of innovation and how to use that knowledge in practical ways. This is essential reading for academics and students in the fields of innovation, organisation studies, public administration and public policy, as well as for policymakers and practitioners.
Known for depicting alienation, frustration, and the victimization of the individual by impenetrable bureaucracies, Kafka's works have given rise to the term Kafkaesque. This encyclopedia details Kafka's life and writings. Included are more than 800 alphabetically arranged entries on his works, characters, family members and acquaintances, themes, and other topics. Most of the entries cite works for further reading, and the Encyclopedia closes with a selected, general bibliography.
The format of this monograph is three essays, which we arrived at after spending a year writing over one hundred pages of what we even tually realized was a tedious reworking of old material. So we started over determined to write something new. At first we thought this approach might not work as a coherent mono graph, which is why we chose the essay format rather than chapters. As it turns out, there is a common thread—namely the directional distance function, which also gave us our title. As you shall see, the directional distance function includes traditional distance functions and efficiency measures as special cases providing a unifying framework for existing productivity and efficiency measures. It is also flexible enough to open up new areas in productivity and efficiency analysis such as environmen tal and aggregation issues. That we did not see this earlier is humbling; a student at a recent conference raised his hand and asked 'Why didn't you start with the directional distance function in the first place? In deed. This manuscript is intended to make up for our earlier oversights. This monograph contains papers coauthored with Wen-Fu Lee and Osman Zaim and one paper written by two former students, Hiroyuki Fukuyama and Bill Weber. We thank them for their contributions. An other former student, Jim Logan (Logi) read and critiqued the manu script for which we are grateful.
Philosophers have mused over them, poets have written about them and musicians have sung about them. Love, desire and passion will at some point touch everyone's life - yet they are little understood and some of the oldest mysteries of mankind. Why do people fall in love and what is love anyway? What makes people attractive? How do these emotions tie in with our physiology and how we have evolved? Lust and Love: Is it more than Chemistry? provides answers to some of these questions through the eyes of science. It takes a light hearted and entertaining approach in explaining the current scientific knowledge of why people are attracted to each other, from the first moments of meeting to how emotions change in a long lasting partnership. The book covers research from the fields of chemistry, biochemistry, neurology, psychiatry, psychology, physics and medicine while using the love story of a fictional couple to take the reader on a journey explaining the science. Additional topics on the 'tools of attraction', including the history of the lipstick, and the development of perfumes and aphrodisiacs, provide an absorbing insight into the subject. Medical treatments and conditions including contraception, erectile dysfunction and the climacteric phenomenon are also discussed. This engaging and unusual book is ideal for anyone interested in the science behind love, desire and passion.
This Brief fills a gap in criminological literature, as there are few empirically-based studies on delinquency of adolescent girls. It provides results of a longitudinal study, The Pittsburgh Girls Study (PGS), which includes 2,451 girls, followed annually from age 10-19, the ages when criminal behavior tends to emerge. This study provides the most extensive and comprehensive investigation into the criminal offending and self-reported trajectories of offending of PGS participants, along with an in-depth examination of other criminal career dimensions. In five chapters, this short volume reviews the limited extent of girls' delinquency literature, presents data on girls' offending patterns (onset, persistence, specialization, and desistence), provides insights on gender differences by comparison with the Pittsburgh Youth Study, which focused on male offenders, and explores the theoretical and practical implications of the results. By understanding the origins and onset of criminal behavior in girls, researchers can begin to understand effective interventions and crime prevention. This Brief will be of interest to researchers in criminology and criminal justice, as well as related fields such as sociology, public policy, and psychology.
The present volume finalizes the coverage of organocopper compounds. A complete formula and ligand index for the Gmelin organocopper series will appear shortly as" Organa copper Compounds" 5. The volume describes mononuclear compounds with ligands bonded by two or more carbon atoms as well as all di- to octanuclear and polymeric compounds. Mononuclear compounds with ligands bonded by one carbon atom have already been described in Vol umes 1 (published in 1985), 2 (published in 1983), and 3 (published in 1986). As structural elucidation in organocopper chemistry gained more attention only in the last few years, the terms "mononuclear", "dinuclear" etc. have been used as explained in "Organocopper Compounds" 1, 1985, pp. 3/4: all compounds are treated with their small est formula unit unless a higher nuclearity has been proved. As a consequence, most of the species treated in volumes 1 to 3 are described there because of insufficient structural information although they are alleged not to be monomeric. This way, many of the better characterized compounds appear in the present volume which is reflected by the more than eighty X-ray structure figures. Generally, nuclearity and structure are not only deter mined by the coordination properties of the ligands, but also by steric requirements, and may therefore widely differ for analogous compounds. For abbreviations and dimensions used throughout this volume, see p. X. Frankfurt am Main, July 1987 Johannes Fussel Remarks on Abbreviations and Dimensions Most compounds and reagents in this volume are presented in tables.
Infrastructures are complex networks dominated by tight interdependencies between technologies and institutions. These networks supply services crucial to modern societies, services that can be provided only if several critical functions are fulfilled. This book proposes a theoretical framework with a set of concepts to analyse rigorously how these critical functions require coordination within the technological dimension as well as within the institutional dimension. It also shows how fundamental the alignment between these two dimensions is. It argues that this alignment operates along different layers characterized successively by the structure, governance and transactions that connect technologies and institutions. These issues of coordination and alignment, at the core of the book, are substantiated through in-depth case studies of networks from the energy, water and wastewater, and transportation sectors.
Since the 1980s, strategic sealift has been formally designated as a U.S. Navy mission. With over ninety percent of all military equipment and supplies required to support U.S. military forces in combat being delivered by sea, and as globalized interests and risks continue to spread, this mission is vital to the country’s economic and national security. Despite its necessity, sealift is rarely discussed as anything other than an operations adjunct and must be carried out in an environment of unprecedented fiscal constraints. Global Reach provides a unique examination into the development and implementation of more than a century of U.S. national defense sealift policy. Presenting a comprehensive history on the evolution of sealift from the Spanish American War (1898) to Operation Enduring Freedom/Iraqi Freedom (2002–12), Herberger, Gaulden, and Marshall reflect on what has and has not worked in that time from both a legal and operational perspective. As international demands grow and change, so too must the sealift policies that are directly tied to how the nation will address them. With its thorough history and cogent analysis, Global Reach provides the context necessary to understand this complex, important topic, but also lays out a roadmap for how the U.S. can continue to meet and respond to the increasing challenges of the years to come.
Spheroid Culture in Cancer Research describes the various techniques now available for establishing spheroid tissue culture, including spheroid culture from normal tissues and from tumor cell lines. The book also describes how the spheroid system can be used to study interactions between normal and malignant cells. Microenvironmental conditions in spheroids and how this micromilieu may promote cellular heterogeneity and histiotypic structures not observed in corresponding monolayer cultures are discussed. The biological importance of oxygen tension, pH gradients, diffusions of nutrients, and cell-cell communication in spheroids are also examined. The book will be profoundly important to researchers in experimental chemotherapy, radiotherapy, immunotherapy, and hyperthermia.
The book is based on documentary and biographical materials that have only recently become available. As the narrative follows the Institute for Social Research from Frankfurt am Main to Geneva, New York, and Los Angeles, and then back to Frankfurt, Wiggershaus continually ties the evolution of the school to the changing intellectual and political contexts in which it operated.
A guide to designing school library media centers that provides information on addressing the unique ergonomic and technology needs of children, controling costs using proven bidding and evaluation methods, understanding the technical drawings and language used in architecture, and other related topics.
The International Council for Industrial and Applied Mathematics (ICIAM) is the worldwide organization of societies which are dedicated primarily or significantly to applied and/or industrial mathematics. The ICIAM Congresses, held every 4 years, are run under the auspices of the Council with the aim to advance the applications of mathematics in all parts of the world. The Sixth ICIAM Congress was held in Zurich, Switzerland, July 16-20, 2007, and was attended by more than 3000 scientists from 47 countries. This volume collects the invited lectures of this Congress, the appreciations of the ICIAM Prize winners' achievements, and the Euler Lecture celebrating the 300th anniversary of Euler. The authors of these papers are leading researchers in their fields, rigorously selected by a distinguished international program committee. The book presents an overview of contemporary applications of mathematics, new perspectives, and open problems. Topics embrace analysis of and numerical methods for: linear and nonlinear partial differential equations multiscale modeling nonlinear problems involving integral operators controllability and observability asymptotic solutions of Hamilton-Jacobi equations contact problems in solid mechanics topology optimization of structures dissipation inequalities in systems theory greedy algorithms sampling in function space order-value optimization parabolic partial differential equations and deterministic games Moreover, particular applications involve risk in financial markets, radar imaging, brain dynamics, and complex geometric optics applied to acoustics and electromagnetics.
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