Ch. 1. Toxicology 101 -- ch. 2. What's the risk -- ch. 3. The risk exercises -- ch. 4. Introduction to the immune system -- ch. 5. How the immune system develops -- ch. 6. The special conditions of pregnancy and the immune system -- ch. 7. The healthy immune system at work -- ch. 8. The dysfunctional immune system and its features -- ch. 9. Avenues for immune exposure -- ch. 10. Diseases stemming from prenatal and early life toxic exposures -- ch. 11. The disease progression matrix -- ch. 12. Categories of environmental, physical and psychological factors -- ch. 13. Prenatal strategies for preventing immune system damage -- ch. 14. Strategies to use during the first few years of life -- ch. 15. Undoing the damage of the past in adulthood -- ch. 16. Top 25 risks -- ch. 17. Other risk factors -- ch. 18. Postnatal triggers of disease - infections -- ch. 19. Postnatal triggers of disease - vaccinations -- ch. 20. Dietary factors that affect the immune system -- ch. 21. Hygiene and pets -- ch. 22. Developmental immunotoxicity testing - past, present and future
Science Sifting is designed primarily as a textbook for students interested in research and as a general reference book for existing career scientists. The aim of this book is to help budding scientists broaden their capacities to access and use information from diverse sources to the benefit of their research careers.The book describes why the capacity to access and integrate both linear and nonlinear information has been an important historic feature of pivotal scientific breakthroughs. Yet, it is a process that our students are rarely, if ever, taught in universities. This book goes beyond simply describing the features of great scientific breakthroughs. It discusses the basis for accessing and using nonlinear information in the linear research context. It also provides a series of tools and exercises that can be used to enhance access to nonlinear information for application to research and other endeavors.Topics covered include focal points in scientific breakthroughs, the use of concepts maps in research, use of different vantage points, information as patterns, fractals for the scientist, memory storage and access points, and synchronicities. Young researchers need useful tools to help with a more holistic approach to their research careers. This book provides the useful tools to support flexibility and creativity across a long-term research career.Roald Hoffmann — Winner of the 1981 Nobel Prize in Chemistry — has contributed the to Science Sifting. More information on Professor Hoffmann can be found at .
Eyeopening... Fascinating... may presage a paradigm shift in medicine.” —Kirkus Reviews (starred review) "Teeming with information and big ideas... Outstanding.” —Booklist (starred review) The origin of asthma, autism, Alzheimer's, allergies, cancer, heart disease, obesity, and even some kinds of depression is now clear. Award-winning researcher on the microbiome, professor Rodney Dietert presents a new paradigm in human biology that has emerged in the midst of the ongoing global epidemic of noncommunicable diseases. The Human Superorganism makes a sweeping, paradigm-shifting argument. It demolishes two fundamental beliefs that have blinkered all medical thinking until very recently: 1) Humans are better off as pure organisms free of foreign microbes; and 2) the human genome is the key to future medical advances. The microorganisms that we have sought to eliminate have been there for centuries supporting our ancestors. They comprise as much as 90 percent of the cells in and on our bodies—a staggering percentage! More than a thousand species of them live inside us, on our skin, and on our very eyelashes. Yet we have now significantly reduced their power and in doing so have sparked an epidemic of noncommunicable diseases—which now account for 63 percent of all human deaths. Ultimately, this book is not just about microbes; it is about a different way to view humans. The story that Dietert tells of where the new biology comes from, how it works, and the ways in which it affects your life is fascinating, authoritative, and revolutionary. Dietert identifies foods that best serve you, the superorganism; not new fad foods but ancient foods that have made sense for millennia. He explains protective measures against unsafe chemicals and drugs. He offers an empowering self-care guide and the blueprint for a revolution in public health. We are not what we have been taught. Each of us is a superorganism. The best path to a healthy life is through recognizing that profound truth.
Compendium of Scottish Silver II is the most comprehensive catalog of Scottish silver and gold published to date and is an essential reference for readers of art, antiques and history. More than 6,000 descriptions of pieces from the 14th-21st centuries are organized chronologically by category (e.g. bowls, mugs, flatware, teapots, etc.) with 54 photos introducing categories. A timeline aids readers in dating pieces and evaluating rarity, and a glossary defines decorative arts terms. Expanded from the original Compendium, a Cornell University Digital Library project, Compendium II has more than 1,000 new listings of provincial, 19th century and special collections silver. Additionally, there is a guide to interpreting Scottish hallmarks and evaluating Scottish silver designed to help the reader avoid common pitfalls.
Guide to the Edinburgh goldsmiths and apprentices. This volume includes details of their maker's marks, training, output, and demographics. The book is a must for those interested in British silver. It is also important for other silver collectors and researchers since many Edinburgh trained craftsmen immigrated elsewhere.
Chronic diseases are the leading cause of deaths worldwide and according to the World Economics Council and the Harvard School of Public Health, the cost of chronic diseases is expected to reach a staggering 48% of global gross domestic product by the year 2030. The urgency of the issue was demonstrated in 2011 when for only the second time in its existence, the U.N. General Assembly brought a health issue to the floor for consideration: chronic diseases. To date, most considerations of the issue have approached the topic from the vantage point that chronic diseases are a myriad of largely unconnected diseases and conditions arising in diverse tissues, organs and physiological systems. This book, Immunotoxicity, Immune Dysfuction, and Chronic Disease, deviates from that prior model. It considers the interconnectivity of chronic diseases with both environmental insult of the immune system and subsequent immune dysfunction and inflammatory dysregulation as the underlying basis for many, if not most, chronic diseases. This change in the perception of environment-immune linkages to chronic disease is significant and has immediate implications both for the prevention of disease as well as for the development of more effective therapeutic approaches. Rather than considering environmental factors and types of reported immune alterations (e.g., depressed humoral immunity) as is common in books involving immunotoxicity, the present book approaches the environment-immune-disease triad from the standpoint of the disease. Each chapter emphasizes one or more specific immune dysfunction-based chronic disease(s) or condition(s) (e.g., asthma, atherosclerosis, multiple sclerosis, lupus) and describes: 1) the suggested environmental risk factors, 2) the underlying immune dysfunction(s) associated with the disease and 3) the overall health consequences of the disease. This book is an early entry for a new Toxicology book series for Springer titled: Molecular and Integrative Toxicology (MaIT). The series will feature detailed research information, but in the context of a more integrative or holistic framework. As part of this framework, the chapters will contain a section on ”Key Points” as well as “Recommendations” where appropriate. The goal is to cover the most timely, state-of-the-art issues in toxicology as well as to ensure that the information is maximally accessible for research scientists, teachers, physicians and students. We are particularly grateful to the numerous chapter authors for providing comprehensive and expert disease-oriented contributions. We are also appreciative of their willingness to consider their material not as disparate pieces of what has become a major health crisis, but rather as key pieces in a network of apparently interconnected health challenges.
Science Sifting is designed primarily as a textbook for students interested in research and as a general reference book for existing career scientists. The aim of this book is to help budding scientists broaden their capacities to access and use information from diverse sources to the benefit of their research careers.The book describes why the capacity to access and integrate both linear and nonlinear information has been an important historic feature of pivotal scientific breakthroughs. Yet, it is a process that our students are rarely, if ever, taught in universities. This book goes beyond simply describing the features of great scientific breakthroughs. It discusses the basis for accessing and using nonlinear information in the linear research context. It also provides a series of tools and exercises that can be used to enhance access to nonlinear information for application to research and other endeavors.Topics covered include focal points in scientific breakthroughs, the use of concepts maps in research, use of different vantage points, information as patterns, fractals for the scientist, memory storage and access points, and synchronicities. Young researchers need useful tools to help with a more holistic approach to their research careers. This book provides the useful tools to support flexibility and creativity across a long-term research career.Roald Hoffmann — Winner of the 1981 Nobel Prize in Chemistry — has contributed the to Science Sifting. More information on Professor Hoffmann can be found at .
Compendium of Scottish Silver II is the most comprehensive catalog of Scottish silver and gold published to date and is an essential reference for readers of art, antiques and history. More than 6,000 descriptions of pieces from the 14th-21st centuries are organized chronologically by category (e.g. bowls, mugs, flatware, teapots, etc.) with 54 photos introducing categories. A timeline aids readers in dating pieces and evaluating rarity, and a glossary defines decorative arts terms. Expanded from the original Compendium, a Cornell University Digital Library project, Compendium II has more than 1,000 new listings of provincial, 19th century and special collections silver. Additionally, there is a guide to interpreting Scottish hallmarks and evaluating Scottish silver designed to help the reader avoid common pitfalls.
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