Robin Whelpton's Books

Introduction to Drug Disposition and Pharmacokinetics

By: Stephen H. Curry,Robin Whelpton

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Introduction to Drug Disposition and Pharmacokinetics

By: Stephen H. Curry,Robin Whelpton

The application of knowledge of drug disposition, and skills in pharmacokinetics, are crucial to the development of new drugs and to a better understanding of how to achieve maximum benefit from existing ones. The book takes the reader from basic concepts to a point where those who wish to will be able to perform pharmacokinetic calculations and be ready to read more advanced texts and research papers. The book will be of benefit to students of medicine, pharmacy, pharmacology, biomedical sciences and veterinary science, including those who have elected to study the topic in more detail, such as via electives and special study modules. It will be of benefit to those involved in drug discovery and development, pharmaceutical and medicinal chemists, as well as budding toxicologists and forensic scientists who require the appropriate knowledge to interpret their findings and as an introductory text for clinical pharmacologists. Early chapters describe the basic principles of the topic while the later ones illustrate the application of those principles to modern approaches to drug development and clinical use. Full colour illustrations facilitate the learning experience and supporting material for course leaders and students can be found on the Companion Web Site "Another book on PK? Yes and there should be and it should be DD & PK. It is good, unique, and does fill a currently unmet need for those working in the xenobiotic arena. DD & PK is just like the perfect mystery novel—the one “you just can’t put down.” However, unlike a mystery novel which requires only one reading to find the answer, the reader of DD & PK will learn more than an answer to a single question. The reader will find many solutions to a wide variety of mysterious problems associated with the time course and actions of xenobiotics." —International Journal of Toxicology, John A. Budny, PhD, President, PharmaCal, Ltd, 2018 "This book has many innovations that make a welcome addition to the bookshelves of a wide range of pharmaceutical scientists. The effective use of ﬁgures and tables to summarize and clarify a wide range of issues is to be commended, as are the learning objectives at the start of the chapter coupled with the summary at the end providing a succinct way in understanding the objectives of the chapter and together with links to a website provides accessibility for all from the neophyte pharmacokineticist to the consultant physician. A book all in the Pharma industry should be aware of." —Int. J. of Pharmacokinetics, Howard M. Hill, ResolvPharma, 2018 "Overall, Introduction to Drug Disposition and Pharmacokinetics oﬀers its readership an in-depth view of classic pharmacokinetic concepts. This book would be an excellent choice for a pharmacokinetics elective or as an adjunctive text for an introductory course. This book reviews a wide array of clinically relevant topics and encourages the reader to apply the knowledge gained to all medi-cations. A robust and varied amount of online material is provided to enhance understanding and encourage discussion. It is likely that all readers, novice or experienced pharmacists, would ﬁnd value in this textbook." — Currents in Pharmacy Teaching and Learning, Milena McLaughlin, Midwestern University Chicago College of Pharmacy, 2018 "In summary, this is an excellent textbook for students new to the field of pharmaceutics and medical, pharmacy, and veterinary students, particularly those who envision a career in drug development research in either academia or industry." —Veterinary Pathology Review, John K. Amory, University of Washington, 2018

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340

Publisher

John Wiley & Sons

Published Date

ISBN 10

111926104X

ISBN 13

9781119261049

Electrochemical Detection in HPLC

Analysis of Drugs and Poisons

By: Robert James Flanagan,David Perrett,Robin Whelpton

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Electrochemical Detection in HPLC

Analysis of Drugs and Poisons

By: Robert James Flanagan,David Perrett,Robin Whelpton

Electrochemical Detection in HPLC: Analysis of Drugs and Poisons is the first monograph devoted to the application of this mode of analysis to the assay of exogenous compounds such as drugs in biological fluids and associated areas. The introductory chapters provide information on basic electrochemistry and HPLC-ED, and on trouble-shooting. The specialized area of thiol analysis is also discussed in detail. Salient practical details of published applications of the technique in analytical toxicology and related areas are provided in a standard format. Alternative techniques are suggested throughout. The emphasis is on the analysis of exogenous compounds, although catecholamines and other endogenous species are discussed in so far as they may be used as drugs. The practical nature of this book will make it useful to professionals working in the field. It will also be of benefit to analysts wishing to use HPLC-ED in the analysis of biological samples for analytes not specifically covered in the volume.

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Page Count

258

Publisher

Royal Society of Chemistry

Published Date

ISBN 10

0854045325

ISBN 13

9780854045327

Drug Disposition and Pharmacokinetics

Principles and Applications for Medicine, Toxicology and Biotechnology

By: Stephen H. Curry,Robin Whelpton

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Drug Disposition and Pharmacokinetics

Principles and Applications for Medicine, Toxicology and Biotechnology

By: Stephen H. Curry,Robin Whelpton

Drug Disposition and Pharmacokinetics The most up-to-date edition of a leading reference in drug disposition and pharmacokinetics In this new, fully-revised edition of Drug Disposition and Pharmacokinetics: Principles and Applications for Medicine, Toxicology and Biotechnology the authors deliver an authoritative and comprehensive discussion of the fate of drug molecules in the body, as well as its implications for pharmacological and clinical effects. The text offers a unique and balanced approach that combines discussion of the specific physical and biological factors affecting the absorption, distribution, metabolism, and excretion of drugs, with mathematical assessments of plasma and body fluid concentrations. The book assumes little prior knowledge and is an ideal reference for practicing professionals in industry as well as researchers and academics. This latest edition provides readers with a new introductory chapter, as well as new chapters covering monoclonal antibodies, the role of stereochemistry in drug disposition and pharmacokinetics, DMPK in non-human species, and the recent use of AI in drug development. Readers will also find: Thorough introductions to drug disposition, pharmacokinetics, and pharmacokinetic modeling In-depth treatments of the kinetics of drug elimination and the relationship between concentration and effect, including PK–PD modeling Comprehensive discussions of predictive pharmacokinetics and the disposition of biological molecules, including peptides and monoclonal antibodies Detailed examinations of the effects of sex, pregnancy, age, and disease, as well as drug monitoring in therapeutics and the use of AI in drug development and treatment Perfect for professionals and researchers working with the scientific aspects of drug disposition in human and veterinary medicine, toxicology, and pharmacology. Drug Disposition and Pharmacokinetics will earn a place in the libraries of students of senior-level courses in pharmacy.

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484

Publisher

John Wiley & Sons

Published Date

ISBN 10

1119589231

ISBN 13

9781119589235

Fundamentals of Analytical Toxicology

By: Robert J. Flanagan,Andrew A. Taylor,Ian D. Watson,Robin Whelpton

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Fundamentals of Analytical Toxicology

By: Robert J. Flanagan,Andrew A. Taylor,Ian D. Watson,Robin Whelpton

The analytical toxicologist may be required to detect, identify, and in many cases measure a wide variety of compounds in samples from almost any part of the body or in related materials such as residues in syringes or in soil. This book gives principles and practical information on the analysis of drugs and poisons in biological specimens, particularly clinical and forensic specimens. After providing some background information the book covers aspects of sample collection, transport, storage and disposal, and sample preparation. Analytical techniques - colour tests and spectrophotometry, chromatography and electrophoresis, mass spectrometry, and immunoassay – are covered in depth, and a chapter is devoted to the analysis of trace elements and toxic metals. General aspects of method implementation/validation and laboratory operation are detailed, as is the role of the toxicology laboratory in validating and monitoring the performance of point of care testing (POCT) devices. The book concludes with reviews of xenobiotic absorption, distribution and metabolism, pharmacokinetics, and general aspects of the interpretation of analytical toxicology results. A clearly written, practical, integrated approach to the basics of analytical toxicology. Focuses on analytical, statistical and pharmacokinetic principles rather than detailed applications. Assumes only a basic knowledge of analytical chemistry. An accompanying website provides additional material and links to related sites. Written by an experienced team of authors,Fundamentals of Analytical Toxicology is an invaluable resource for those starting out in a career in analytical toxicology across a wide range of disciplines including clinical and forensic science, food safety, and pharmaceutical development. Praise from the reviews: “This is an ambitious effort to describe in detail the many and varied aspects of the science of toxicological analysis. The 17 chapters cover every foreseeable aspect, from specimen collection through analytical techniques and quality control to pharmacological principles and interpretation of results. The authors bring together a great deal of experience in the field and have succeeded admirably in achieving their goal: "to give principles and practical information on the analysis of drugs, poisons and other relevant analytes in biological specimens...". The book is very readable and quite up-to-date, and contains many illustrative figures, charts and tables. Both the student and the practicing professional would do well to study this material carefully, as there is something here for every conceivable level of interest.” Review from Randall Baselt "This text comes highly recommended for any analytical toxicology trainee." The Bulletin of the Royal College of Pathologists “Overall, this book provides a comprehensive, thorough, clear, up to date and practical treatment of analytical toxicology at a high standard. Understanding of the text is enhanced by the use of many illustrations. Specifications, guidelines, and methods are highlighted in grey background “Boxes”. The many and up to date literature references in each chapter demonstrate the authors’ thorough work and permit easy access to deeper information. Therefore this book can be highly recommended as a valuable source of knowledge in analytical toxicology both as an introduction and for the advanced reader.” GTFCh Bulletin “Toxichem + Krimtech”, May 2008 (translated, original review in German) “Many toxicologists will add this important reference to their libraries because it competently fills a need ...” International Journal of Toxicology “The book is very well illustrated, easy to understand and pleasant to read, and contains a wealth of dedicated information.” International Journal of Environmental Analytical Chemistry

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Page Count

605

Publisher

John Wiley & Sons

Published Date

ISBN 10

0470319348

ISBN 13

9780470319345

Globalization and International Education

By: Robin Shields

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Globalization and International Education

By: Robin Shields

Considers the key international issues in education and investigates the changes stemming from the rapid social, economic and cultural transformations associated with globalization.

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Page Count

161

Publisher

A&C Black

Published Date

ISBN 10

1441135766

ISBN 13

9781441135766

Vlakplaas

Apartheid Death Squads, 1979–1994

By: Robin Binckes

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Vlakplaas

Apartheid Death Squads, 1979–1994

By: Robin Binckes

Faced with the total onslaught by its enemies, in 1979, Apartheid South Africa established Vlakplaas lit. shallow farm, a 100-hectare farm nestling in the hills outside Pretoria on the Hennops River as a secret operation under the arm of C1, a counter-terrorism division of the South African Police headed by Brigadier Schoon.The first phase of Vlakplaas operations, up until 1989, was aimed at fighting the enemy: the armed wings of the liberation movements, the African National Congresss Umkhonto we Sizwe (or MK), the Pan Africanist Congresss Azanian Peoples Liberation Army (or APLA) and the South African Communist Party. The second phase was fighting organized crime in which Vlakplaas itself seamlessly adopted the mantle of organized crime in the notorious downtown area of Johannesburgs Hillbrow. The final phase, the most destructive, was as the murky Third Force that destabilized the country in an orgy of violence in the run-up to its first democratic elections, in 1994.Operating within South Africa as well as beyond the countrys borders, it will never been known how many victims can be attributed to the Vlakplaas agenda with much of the execution taking place on the farm itself but a conservative figure of 1,000 murders and assassinations has been mooted.

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Page Count

189

Publisher

Pen and Sword

Published Date

ISBN 10

1526729229

ISBN 13

9781526729224

Fundamentals of Analytical Toxicology

Clinical and Forensic

By: Robert J. Flanagan,Eva Cuypers,Hans H. Maurer,Robin Whelpton

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Fundamentals of Analytical Toxicology

Clinical and Forensic

By: Robert J. Flanagan,Eva Cuypers,Hans H. Maurer,Robin Whelpton

Fundamentals of Analytical Toxicology is an integrated introduction to the analysis of drugs, poisons, and other foreign compounds in biological and related specimens. Assuming only basic knowledge of analytical chemistry, this invaluable guide helps trainee analytical toxicologists understand the principles and practical skills involved in detecting, identifying, and measuring a broad range of compounds in various biological samples. Clear, easy-to-read chapters provide detailed information on topics including sample collection and preparation, spectrophotometric and luminescence techniques, liquid and gas-liquid chromatography, and mass spectrometry including hyphenated techniques. This new edition contains thoroughly revised content that reflects contemporary practices and advances in analytical methods. Expanding the scope of the 1995 World Health Organization (WHO) basic analytical toxicology manual, the text includes coverage of separation science, essential pharmacokinetics, xenobiotic absorption, distribution and metabolism, clinical toxicological and substance misuse testing, therapeutic drug monitoring, trace elements and toxic metals analysis, and importantly the clinical interpretation of analytical results. Written by a prominent team of experienced practitioners, this volume: Focuses on analytical, statistical, and pharmacokinetic principles Describes basic methodology, including colour tests and immunoassay and enzyme-based assays Outlines laboratory operations, such as method validation, quality assessment, staff training, and laboratory accreditation Follows IUPAC nomenclature for chemical names and recommended International Non-proprietary Name (rINN) for drugs and pesticides Includes discussion of 'designer drugs' (novel pharmaceutical substances NPS) Fundamentals of Analytical Toxicology: Clinical and Forensic, 2nd Edition is an indispensable resource for advanced students and trainee analytical toxicologists across disciplines, such as clinical science, analytical chemistry, forensic science, pathology, applied biology, food safety, and pharmaceutical and pesticide development.

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Page Count

648

Publisher

John Wiley & Sons

Published Date

ISBN 10

1119122368

ISBN 13

9781119122364

Fundamentals of Analytical Toxicology

By: Robert J. Flanagan,Andrew A. Taylor,Ian D. Watson,Robin Whelpton

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Fundamentals of Analytical Toxicology

By: Robert J. Flanagan,Andrew A. Taylor,Ian D. Watson,Robin Whelpton

The analytical toxicologist may be required to detect, identify,and in many cases measure a wide variety of compounds in samplesfrom almost any part of the body or in related materials such asresidues in syringes or in soil. This book gives principles andpractical information on the analysis of drugs and poisons inbiological specimens, particularly clinical and forensic specimens. After providing some background information the book coversaspects of sample collection, transport, storage and disposal, andsample preparation. Analytical techniques - colour tests andspectrophotometry, chromatography and electrophoresis, massspectrometry, and immunoassay – are covered in depth, and achapter is devoted to the analysis of trace elements and toxicmetals. General aspects of method implementation/validation andlaboratory operation are detailed, as is the role of the toxicologylaboratory in validating and monitoring the performance of point ofcare testing (POCT) devices. The book concludes with reviews ofxenobiotic absorption, distribution and metabolism,pharmacokinetics, and general aspects of the interpretation ofanalytical toxicology results. A clearly written, practical, integrated approach to the basicsof analytical toxicology. Focuses on analytical, statistical and pharmacokineticprinciples rather than detailed applications. Assumes only a basic knowledge of analytical chemistry. An accompanying website provides additional material and linksto related sites. Written by an experienced team of authors,Fundamentals ofAnalytical Toxicology is an invaluable resource for thosestarting out in a career in analytical toxicology across a widerange of disciplines including clinical and forensic science, foodsafety, and pharmaceutical development. Praise from the reviews: “This is an ambitious effort to describe in detail themany and varied aspects of the science of toxicological analysis.The 17 chapters cover every foreseeable aspect, from specimencollection through analytical techniques and quality control topharmacological principles and interpretation of results. Theauthors bring together a great deal of experience in the field andhave succeeded admirably in achieving their goal: "to giveprinciples and practical information on the analysis of drugs,poisons and other relevant analytes in biological specimens...".The book is very readable and quite up-to-date, and contains manyillustrative figures, charts and tables. Both the student and thepracticing professional would do well to study this materialcarefully, as there is something here for every conceivable levelof interest.” Review from RandallBaselt "This text comes highly recommended for any analyticaltoxicology trainee." The Bulletin of the Royal College ofPathologists “Overall, this book provides a comprehensive, thorough,clear, up to date and practical treatment of analytical toxicologyat a high standard. Understanding of the text is enhanced bythe use of many illustrations. Specifications, guidelines,and methods are highlighted in grey background“Boxes”. The many and up to date literaturereferences in each chapter demonstrate the authors’ thoroughwork and permit easy access to deeper information. Thereforethis book can be highly recommended as a valuable source ofknowledge in analytical toxicology both as an introduction and forthe advanced reader.” GTFCh Bulletin“Toxichem + Krimtech”, May 2008 (translated,original review in German) “Many toxicologists will add this important referenceto their libraries because it competently fills a need...” International Journal of Toxicology “The book is very well illustrated, easy to understandand pleasant to read, and contains a wealth of dedicatedinformation.” International Journal of EnvironmentalAnalytical Chemistry

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Page Count

546

Publisher

John Wiley & Sons

Published Date

ISBN 10

0470516283

ISBN 13

9780470516287

Electrochemical Detection in HPLC

Analysis of Drugs and Poisons

By: Robert J Flanagan,David Perrett,Robin Whelpton

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Electrochemical Detection in HPLC

Analysis of Drugs and Poisons

By: Robert J Flanagan,David Perrett,Robin Whelpton

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Page Count

244

Publisher

Royal Society of Chemistry

Published Date

ISBN 10

184755072X

ISBN 13

9781847550729

Drug Disposition and Pharmacokinetics

Principles and Applications for Medicine, Toxicology and Biotechnology

By: Stephen H. Curry,Robin Whelpton

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Drug Disposition and Pharmacokinetics

Principles and Applications for Medicine, Toxicology and Biotechnology

By: Stephen H. Curry,Robin Whelpton

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Page Count

484

Publisher

John Wiley & Sons

Published Date

ISBN 10

1119589231

ISBN 13

9781119589235

Introduction to Drug Disposition and Pharmacokinetics

By: Stephen H. Curry,Robin Whelpton

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Introduction to Drug Disposition and Pharmacokinetics

By: Stephen H. Curry,Robin Whelpton

The application of knowledge of drug disposition, and skills in pharmacokinetics, are crucial to the development of new drugs and to a better understanding of how to achieve maximum benefit from existing ones. The book takes the reader from basic concepts to a point where those who wish to will be able to perform pharmacokinetic calculations and be ready to read more advanced texts and research papers. The book will be of benefit to students of medicine, pharmacy, pharmacology, biomedical sciences and veterinary science, including those who have elected to study the topic in more detail, such as via electives and special study modules. It will be of benefit to those involved in drug discovery and development, pharmaceutical and medicinal chemists, as well as budding toxicologists and forensic scientists who require the appropriate knowledge to interpret their findings and as an introductory text for clinical pharmacologists. Early chapters describe the basic principles of the topic while the later ones illustrate the application of those principles to modern approaches to drug development and clinical use. Full colour illustrations facilitate the learning experience and supporting material for course leaders and students can be found on the Companion Web Site "Another book on PK? Yes and there should be and it should be DD & PK. It is good, unique, and does fill a currently unmet need for those working in the xenobiotic arena. DD & PK is just like the perfect mystery novel—the one “you just can’t put down.” However, unlike a mystery novel which requires only one reading to find the answer, the reader of DD & PK will learn more than an answer to a single question. The reader will find many solutions to a wide variety of mysterious problems associated with the time course and actions of xenobiotics." —International Journal of Toxicology, John A. Budny, PhD, President, PharmaCal, Ltd, 2018 "This book has many innovations that make a welcome addition to the bookshelves of a wide range of pharmaceutical scientists. The effective use of figures and tables to summarize and clarify a wide range of issues is to be commended, as are the learning objectives at the start of the chapter coupled with the summary at the end providing a succinct way in understanding the objectives of the chapter and together with links to a website provides accessibility for all from the neophyte pharmacokineticist to the consultant physician. A book all in the Pharma industry should be aware of." —Int. J. of Pharmacokinetics, Howard M. Hill, ResolvPharma, 2018 "Overall, Introduction to Drug Disposition and Pharmacokinetics offers its readership an in-depth view of classic pharmacokinetic concepts. This book would be an excellent choice for a pharmacokinetics elective or as an adjunctive text for an introductory course. This book reviews a wide array of clinically relevant topics and encourages the reader to apply the knowledge gained to all medi-cations. A robust and varied amount of online material is provided to enhance understanding and encourage discussion. It is likely that all readers, novice or experienced pharmacists, would find value in this textbook." — Currents in Pharmacy Teaching and Learning, Milena McLaughlin, Midwestern University Chicago College of Pharmacy, 2018 "In summary, this is an excellent textbook for students new to the field of pharmaceutics and medical, pharmacy, and veterinary students, particularly those who envision a career in drug development research in either academia or industry." —Veterinary Pathology Review, John K. Amory, University of Washington, 2018

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Page Count

339

Publisher

John Wiley & Sons

Published Date

ISBN 10

1119261023

ISBN 13

9781119261025

My Song to My Son

By: Barbara Farrell-Moshier Brown

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My Song to My Son

By: Barbara Farrell-Moshier Brown

A song for my son, was written for you change the name and see what kids do. Imaginations are far and few have fun with them also becomes fun for you With learning or play sing kids a song it makes fun for the day. If you rock them to sleep or comfort a fall sooth a baby's belly, a song will cure it all.

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Publisher

Christian Faith Publishing, Incorporated

Published Date

ISBN 10

1098072480

ISBN 13

9781098072483

Book's by Robin Whelpton

Introduction to Drug Disposition and Pharmacokinetics

Introduction to Drug Disposition and Pharmacokinetics

Electrochemical Detection in HPLC

Electrochemical Detection in HPLC

Drug Disposition and Pharmacokinetics

Drug Disposition and Pharmacokinetics

Fundamentals of Analytical Toxicology

Fundamentals of Analytical Toxicology

Globalization and International Education

Globalization and International Education

Vlakplaas

Vlakplaas

Fundamentals of Analytical Toxicology

Fundamentals of Analytical Toxicology

Fundamentals of Analytical Toxicology

Fundamentals of Analytical Toxicology

Electrochemical Detection in HPLC

Electrochemical Detection in HPLC

Drug Disposition and Pharmacokinetics

Drug Disposition and Pharmacokinetics

Introduction to Drug Disposition and Pharmacokinetics

Introduction to Drug Disposition and Pharmacokinetics

My Song to My Son

My Song to My Son

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