Discover a comprehensive exploration of recent progress in the preparation of nitroalkanes from two leading voices in the field Nitroalkanes: Synthesis, Reactivity, and Applications delivers a thorough summary of the importance of nitroalkanes in organic synthesis. The book covers their preparation, transformation into other functional groups, like carbonyls and amines, and their use in the formation of single carbon-carbon or double carbon-carbon bonds. The distinguished authors have included chapters on acyclic and cyclic alpha-nitro ketones as well as the synthesis of cyclopropanes and spiro ketals. The book provides treatments of the application of nitroalkanes for the synthesis of important heterocycles, poly-functionalized structures, natural products, and compounds of biological and pharmaceutical interest. A one-stop resource in a topic that hasn???t been fully addressed by any other book in decades, this book covers the most important synthetic routes toward nitroalkanes. Readers will also benefit from the inclusion of: A thorough introduction to the synthesis of nitroalkanes, as well as the transformation of the nitro group into other functionalities An exploration of the formation of C-C single bonds, C=C double bonds, and the breaking of C3C bonds from cyclic alpha-nitro ketones Discussions of acyclic alpha-nitro ketones, nitroalkanes as precursors of cyclopropanes, and the synthesis of spiro ketals An examination of the preparation and synthetic applications of 1,3-Dinitroalkanes Perfect for organic chemists, natural products chemists, and catalytic chemists, Nitroalkanes: Synthesis, Reactivity, and Applications will also earn a place in the libraries of medicinal chemists seeking a one-stop resource for the most recent developments in the preparation of nitroalkanes, their functionalization, and their applications.
Tonino Valerii is one of Italy's best genre film directors. Starting out as Sergio Leone's assistant on For a Few Dollars More (1965), he went on to direct spaghetti westerns that stand out among the most accomplished in their class--Day of Anger (1967), The Price of Power (1969), A Reason to Live, a Reason to Die! (1972) and My Name Is Nobody (1973). He also directed the outstanding giallo My Dear Killer (1972). This book examines Valerii's life and career in depth for the first time, with exclusive interviews with the filmmaker, scriptwriters and actors, and critical analysis of his films.
Offering a thorough, accessible overview of the basic science and clinical data regarding the virus that causes COVID-19, Molecular Biology of SARS-CoV-2 is an excellent resource for researchers, clinical scientists, physicians, and students. This volume offers in-depth, extended content that originated with Drs. Roberto Patarca’s and William A. Haseltine’s chapter in The COVID-19 Textbook, edited by Dr. Haseltine and Dr. Patarca. The greatly expanded material in this text provides a much-needed primer in this complex area.
Published in 1499 and centered on the figure of a bawd and witch, Fernando de Rojas' dark and disturbing Celestina was destined to become the most suppressed classic in Spanish literary history. Routinely ignored in Spanish letters, the book nonetheless echoes through contemporary Spanish and Latin American literature. This is the phenomenon that Celestina's Brood explores. Roberto González Echevarría, one of the most eminent and influential critics of Hispanic literature writing today, uses Rojas' text as his starting point to offer an exploration of modernity in the Hispanic literary tradition, and of the Baroque as an expression of the modern. His analysis of Celestina reveals the relentless probing of the limits of language and morality that mark the work as the beginning of literary modernity in Spanish, and the start of a tradition distinguished by a penchant for the excesses of the Baroque. González Echevarría pursues this tradition and its meaning through the works of major figures such as Cervantes, Lope de Vega, Calderón de la Barca, Alejo Carpentier, Carlos Fuentes, Gabriel García Márquez, Nicolás Guillén, and Severo Sarduy, as well as through the works of lesser-known authors. By revealing continuities of the Baroque, Celestina's Brood cuts across conventional distinctions between Spanish and Latin American literary traditions to show their profound and previously unimagined affinity.
The COVID-19 Textbook: Science, Medicine, and Public Health explores every facet of SARS-COV-2, giving the reader an understanding of what is needed to control the spread of the virus, prevent and manage its pathological effects, as well as mitigate the impact of future pandemics. Each chapter is authored by leading global experts in the field and includes topics such as molecular biology, epidemiology, pathogenesis, immunology, diagnosis, and the latest prevention and treatment approaches. Edited by renowned educator and medical researcher Dr. William A. Haseltine, physician-researcher, and chronic fatigue syndrome expert Dr. Roberto Patarca, it includes detailed references in every chapter, allowing easy access to comprehensive primary data. • Offers a timely, reliable overview authored and edited by leading global experts in the multifaceted areas covered on SARS-CoV-2 and the COVID-19 pandemic. • Serves as an authoritative and comprehensive text to be utilized by physicians, medical professionals, researchers, students, public health professionals, and policymakers.
Novel processing and searching tools for the management of new multimedia documents have developed. Multimedia Information Retrieval (MIR) is an organic system made up of Text Retrieval (TR); Visual Retrieval (VR); Video Retrieval (VDR); and Audio Retrieval (AR) systems. So that each type of digital document may be analysed and searched by the elements of language appropriate to its nature, search criteria must be extended. Such an approach is known as the Content Based Information Retrieval (CBIR), and is the core of MIR. This novel content-based concept of information handling needs to be integrated with more traditional semantics. Multimedia Information Retrieval focuses on the tools of processing and searching applicable to the content-based management of new multimedia documents. Translated from Italian by Giles Smith, the book is divided into two parts. Part one discusses MIR and related theories, and puts forward new methodologies; part two reviews various experimental and operating MIR systems, and presents technical and practical conclusions. - Gives a complete, organic picture of MIR and CBIR - Proposes a novel conceptualisation around the ideas of Information Retrieval (IR) and digital document management in the context of Library and Information Science (LIS) - Relevant for both library and information science and information technology specialists
« Un bulletin de vote est plus fort qu’une balle de fusil. » 1863, Gettysburg. C’est sur ces plaines de Pennsylvanie que le sang de plus de 50 000 Américains a coulé, permettant à l’armée nordiste de remporter une victoire capitale. Mais à quel prix ? Alors qu’il se rend sur place pour inaugurer le cimetière militaire et prononcer un discours qui fera figure d’Évangile de l’Union, Abraham Lincoln, seizième président de l’histoire des États-Unis, médite sur la fragilité de l’existence et retrace sa propre vie : de son enfance malheureuse dans les prairies du Middle West à la Maison-Blanche en passant ses grandes plaidoiries en tant qu’avocat itinérant et son engagement en politique. Par flashbacks, on suit ainsi le parcours d’un homme brillant, intègre et profondément humaniste. Découvrez la vie du plus grand président américain, tant par la taille que par le destin, réputé pour son honnêteté et son éloquence. Une plongée dans l’histoire turbulente et sanglante des États-Unis, dont certains sujets restent d’une tragique actualité.
Celui qui reçoit la victoire de Dieu. 1187. L’armée de Saladin est aux portes de Jérusalem. Voilà près de cinq ans que le Sultan mène le djihad contre les Francs, s’apprêtant à devenir le premier Musulman à reprendre la ville aux Chrétiens. Mais pour réussir ce tour de force, Saladin a dû dans un premier temps user de tout son talent politique, diplomatique et militaire pour unifier l’ensemble des peuples musulmans d’Arabie, du Caire à Mossoul, et devenir le chef légitime de l’Islam sunnite. La collection « Ils ont fait l’histoire » vous propose de découvrir le destin de l’un des plus grands héros de la culture musulmane qui, bien qu’il ait toujours farouchement combattu les occidentaux, était aussi réputé comme un dirigeant chevaleresque.
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