With the 13th edition, Wintrobe’s Clinical Hematology once again bridges the gap between the clinical practice of hematology and the basic foundations of science. Broken down into eight parts, this book provides readers with a comprehensive overview of: Laboratory Hematology, The Normal Hematologic System, Transfusion Medicine, Disorders of Red Cells, Hemostasis and Coagulation; Benign Disorders of Leukocytes, The Spleen and/or Immunoglobulins; Hematologic Malignancies, and Transplantation. Within these sections, there is a heavy focus on the morphological exam of the peripheral blood smear, bone marrow, lymph nodes, and other tissues. With the knowledge about gene therapy and immunotherapy expanding, new, up-to-date information about the process and application of these therapies is included. Likewise, the editors have completely revised material on stem cell transplantation in regards to both malignant and benign disorders, graft versus host disease, and the importance of long-term follow-up of transplantation survivors.
This textbook offers a comprehensive undergraduate course in real analysis in one variable. Taking the view that analysis can only be properly appreciated as a rigorous theory, the book recognises the difficulties that students experience when encountering this theory for the first time, carefully addressing them throughout. Historically, it was the precise description of real numbers and the correct definition of limit that placed analysis on a solid foundation. The book therefore begins with these crucial ideas and the fundamental notion of sequence. Infinite series are then introduced, followed by the key concept of continuity. These lay the groundwork for differential and integral calculus, which are carefully covered in the following chapters. Pointers for further study are included throughout the book, and for the more adventurous there is a selection of "nuggets", exciting topics not commonly discussed at this level. Examples of nuggets include Newton's method, the irrationality of π, Bernoulli numbers, and the Gamma function. Based on decades of teaching experience, this book is written with the undergraduate student in mind. A large number of exercises, many with hints, provide the practice necessary for learning, while the included "nuggets" provide opportunities to deepen understanding and broaden horizons.
The Problem of the Unknown Component: Theory and Applications addresses the issue of designing a component that, combined with a known part of a system, conforms to an overall specification. The authors tackle this problem by solving abstract equations over a language. The most general solutions are studied when both synchronous and parallel composition operators are used. The abstract equations are specialized to languages associated with important classes of automata used for modeling systems. The book is a blend of theory and practice, which includes a description of a software package with applications to sequential synthesis of finite state machines. Specific topologies interconnecting the components, exact and heuristic techniques, and optimization scenarios are studied. Finally the scope is enlarged to domains like testing, supervisory control, game theory and synthesis for special omega languages. The authors present original results of the authors along with an overview of existing ones.
This revised edition of this unique textbook is specifically designed for statistics and probability courses taught to students of forestry and related disciplines. It introduces probability, statistical techniques, data analysis, hypothesis testing, experimental design, sampling methods, nonparametric tests and statistical quality control, using examples drawn from a forestry, wood science and conservation context. The book now includes several new practical exercises for students to practice data analysis and experimental design themselves. It has been updated throughout, and its scope has been broadened to reflect the evolving and dynamic nature of forestry, bringing in examples from conservation science, recreation and urban forestry.
What if something as seemingly academic as the so-called science wars were to determine how we live? This eye-opening book reveals how little we've understood about the ongoing pitched battles between the sciences and the humanities--and how much may be at stake. James Brown's starting point is C. P. Snow's famous book, Two Cultures and the Scientific Revolution, which set the terms for the current debates. But that little book did much more than identify two new, opposing cultures, Brown contends: It also claimed that scientists are better qualified than nonscientists to solve political and social problems. In short, the true significance of Snow's treatise was its focus on the question of who should rule--a question that remains vexing, pressing, and politically explosive today. In Who Rules in Science? Brown takes us through the various engagements in the science wars--from the infamous "Sokal affair" to angry confrontations over the nature of evidence, the possibility of objectivity, and the methods of science--to show how the contested terrain may be science, but the prize is political: Whoever wins the science wars will have an unprecedented influence on how we are governed. Brown provides the most comprehensive and balanced assessment yet of the science wars. He separates the good arguments from the bad, and exposes the underlying message: Science and social justice are inextricably linked. His book is essential reading if we are to understand the forces making and remaking our world.
The second edition of this established text contains everything students need to know about written communication. Includes advice on writing essays, letters, preparing a dissertation and on how to find out information for a project or essay
Log buildings are embedded deeply into North American history and culture. For more than one thousand years, builders have been weaving logs into homes, shelters, barns, and churches. Today, however, the buildings where we live and work are rarely handmade from natural materials. In this context, handcrafted, scribe-fitted natural log buildings are an attractive and uplifting alternative to conventional buildings and building materials. This book tells you what you need to know to build your own log home and also reveals the deep rhythms and patterns of log construction. Author Robert Chambers shows how to take naturally shaped, tapered, round logs and scribe-fit them one to another so that they look like they actually grew together in the woods. The Log Construction Manual is filled with information available nowhere else, including the Log Selection Rules, Chambers's brilliantly simple method for choosing which log to use next; instructions for building hip and valley log rafters and roof trusses from full-round logs; step-by-step directions for laying out the sill logs for virtually any floor plan, including hexagons, prows, and more; state-of-the-art compression-fit saddle notches and underscribing to keep fits tight over time; details on scribing and cutting long grooves and corner notches just like the pros; and more. Chambers also offers advice on organizing and financing a log home project and has loads of experience to share on cutting costs and avoiding common pitfalls. He presents practical ideas for saving money and controlling costs. Although handcrafted log homes are expensive to buy, they are within reach for many as owner-managed building projects. Writtenconcisely with great care in explaining important details, the Log Construction Manual brings clarity, insight, depth, and even humor to the log builder's craft. This is a comprehensive book for log home owner-builders, beginners as well as professionals.
Detailed, self-contained treatment examines modern abstract methods in partial differential equations, especially abstract evolution equations. Suitable for graduate students with some previous exposure to classical partial differential equations. 1969 edition.
This book is intended for science and engineering majors who are required to take calculus and are looking for a more intuitive way of understanding it. This is a non-rigorous infinitesimal approach which focuses on differentials of variables that represent physical quantities rather than derivatives as limits of of mathematical functions. In science variables are related in equations so this is the focus rather than on dependent and independent variables of functions. These methods were originally conceived by G. Leibniz over 300 years ago and have been used successfully by scientists ever since.
Comprehensive in scope and thoroughly up to date, Wintrobe’s Clinical Hematology, 15th Edition, combines the biology and pathophysiology of hematology as well as the diagnosis and treatment of commonly encountered hematological disorders. Editor-in-chief Dr. Robert T. Means, Jr., along with a team of expert section editors and contributing authors, provide authoritative, in-depth information on the biology and pathophysiology of lymphomas, leukemias, platelet destruction, and other hematological disorders as well as the procedures for diagnosing and treating them. Packed with more than 1,500 tables and figures throughout, this trusted text is an indispensable reference for hematologists, oncologists, residents, nurse practitioners, and pathologists.
This book describes the essential tools and techniques of statistical signal processing. At every stage theoretical ideas are linked to specific applications in communications and signal processing using a range of carefully chosen examples. The book begins with a development of basic probability, random objects, expectation, and second order moment theory followed by a wide variety of examples of the most popular random process models and their basic uses and properties. Specific applications to the analysis of random signals and systems for communicating, estimating, detecting, modulating, and other processing of signals are interspersed throughout the book. Hundreds of homework problems are included and the book is ideal for graduate students of electrical engineering and applied mathematics. It is also a useful reference for researchers in signal processing and communications.
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