Having received the invitation from Springer-Verlag to produce a volume on drug-induced birth defects for the Handbook of Experimental Pharmacology, we asked ourselves what new approach could we offer that would capture the state of the science and bring a new synthesis of the information on this topic to the world's literature. We chose a three-pronged approach, centered around those particular drugs for which we have a relatively well established basis for understanding how they exert their unwanted effects on the human embryo. We then supplemented this information with a series of reviews of critical biological processes involved in the established normal developmental patterns, with emphasis on what happens to the embryo when the processes are perturbed by experimental means. Knowing that the search for mechanisms in teratology has often been inhibited by the lack of understanding of how normal development proceeds, we also included chapters describing the amazing new discoveries related to the molecular control of normal morphogenesis for several organ systems in the hope that the experimental toxicologists and molecular biologists will begin to better appreciate each others questions and progress. Several times during the last two years of developing outlines, issuing invitations, reviewing chapters, and cajoling belated contributors, we have wondered whether we made the correct decision to undertake this effort.
This book contains the proceedings of the International Symposium on Alternative and Advanced Automotive Engines, held in Vancouver, B.C., on August 11 and 12, 1986. The symposium was sponsored by EXPO 86 and The University of British Columbia, and was part of the specialized periods program of EXPO 86, the 1986 world's fair held in Vancouver. Some 80 attendees were drawn from 11 countries, representing the academic, auto motive and large engine communities. The purpose of the symposium was to provide a critical review of the major alternatives to the internal combustion engine. The scope of the symposium was limited to consideration of combustion engines, so that electric power, for example, was not considered. This was not a reflec tion on the possible contribution which electric propulsion may make in the future, but rather an attempt to focus the proceedings more sharply than if all possible propulsion systems had been considered. In this way all of the contributors were able to participate in the sometimes lively discussion sessions following the presentation of each paper.
The book surveys mathematical relations between classical and quantum mechanics, gravity, time and thermodynamics from various points of view and many sources (with appropriate attribution). The emergence theme is developed with an emphasis on the meaning via mathematics. A background theme of Bohemian mechanics and connections to the quantum equivalence principle of Matone et al. is also developed in great detail. Some original work relating the quantum potential and Ricci flow is also included.
Robert A. Slade, after collecting old fishing tackle since 1958 and contributing articles on old fishing lures for a collector magazine for several years started researching and writing books in the 1990's. He published the HISTORY & COLLECTIBLE FISHING TACKLE OF WISCONSIN in 1999 which sold 4,500 copies. Bob realized that even though there have been many books published on the subject of old fishing lures that few books covered any detailed history on the old lure makers. His latest book writing project was nine years in the making and covers over 100 years of lure making history starting in 1875 and covers over 2,500 lures makers throughout all of North America. THE ENCYCLOPEDIA OF OLD FISHING LURES MADE IN NORTH AMERICA is the first publication with extensive history and patent information on old lure makers and the first to include extensive coverage on Canadian lure makers. The author traveled to 11 states and 3 Candian Providences visting collectors homes, newspaper archives, museums and other sources and has taken over 10,000 pictures in preparing the historical stories for these books. The set of books arranges for the individual and company lures makers to appear in alphabetical order. People purchasing these books can buy any one single book, a whole set, or even a book a month if they desire as the books will be printed and shipped on demand. Each book has over 400 pages of text, pictures and collector values with each book containing a table of contents and index as well as a master index for the complete set of books.
[B]ecause of the thoroughness of the literature reviews and the comprehensive coverage of the chapter topics, [this book] should be required reading for any scholar working in related areas of personality or intelligence."--PsycCRITIQUES "This book is a masterly attempt to bring order and cohesion to a field that for many years has been riven with claims and counterclaims. The editors and authors are to be congratulated for addressing a very complex task so helpfully." John Biggs, PhD Honorary Professor of Psychology University of Hong Kong "If you are interested in intellectual stylesópeople's preferred ways of processing informationóthen this book belongs on your bookshelf." Richard E. Mayer, PhD Professor of Psychology University of California, Santa Barbara "For more than half a century, the construct of styleówhether designated as cognitive, thinking or learningóhas been in or out of fashion in the history of psychology and education. The editors of the present Handbook have invigorated the style construct in the form of intellectual styles, and have brought together a distinguished international panel of chapter authors who offer up-to-date surveys of the assessment, development, correlates, and educational and organizational applications of intellectual styles. For those seeking to familiarize themselves with current theory and research in an intellectually exciting field, the present Handbook is essential." Nathan Kogan, PhD Professor Emeritus, Department of Psychology New School for Social Research, New York, NY The concept of intellectual styles has had a controversial history based on diverse philosophical and theoretical foundations. Most recently, the idea of intellectual stylesóan umbrella term that covers such closely related constructs as "cognitive styles," "learning styles," "teaching styles," and "thinking styles"óhas gained momentum as an explanation for why different people succeed in different professional and organizational settings. Previously, it was thought that high-achievers simply had more innate abilities than their less successful peers, but research has shown that individuals have different intellectual styles that are better suited for varying types of contexts and problems. Based on the most current and expansive research, this handbook is the first to provide a comprehensive review of research on the construct of intellectual style, from its foundations and development, to its relations to allied constructs, its roles in school and job performance, its applications in various populations, and its future.. This understanding of intellectual styles as a valid concept for both individuals and groups has far-reaching implications for researchers in cross-cultural psychology, multicultural education, organizational behavior and work performance, and many other academic disciplines, as well as practitioners in education and beyond. Key Features: Provides a comprehensive review of intellectual styles from multiple perspectives Written for students and scholars in diverse academic arenas, as well as practitioners in education and other fields Includes contributions from researchers from diverse disciplines, such as psychology, business, education, and health sciences
The analytical toxicologist may be required to detect, identify,and in many cases measure a wide variety of compounds in samplesfrom almost any part of the body or in related materials such asresidues in syringes or in soil. This book gives principles andpractical information on the analysis of drugs and poisons inbiological specimens, particularly clinical and forensic specimens. After providing some background information the book coversaspects of sample collection, transport, storage and disposal, andsample preparation. Analytical techniques - colour tests andspectrophotometry, chromatography and electrophoresis, massspectrometry, and immunoassay – are covered in depth, and achapter is devoted to the analysis of trace elements and toxicmetals. General aspects of method implementation/validation andlaboratory operation are detailed, as is the role of the toxicologylaboratory in validating and monitoring the performance of point ofcare testing (POCT) devices. The book concludes with reviews ofxenobiotic absorption, distribution and metabolism,pharmacokinetics, and general aspects of the interpretation ofanalytical toxicology results. A clearly written, practical, integrated approach to the basicsof analytical toxicology. Focuses on analytical, statistical and pharmacokineticprinciples rather than detailed applications. Assumes only a basic knowledge of analytical chemistry. An accompanying website provides additional material and linksto related sites. Written by an experienced team of authors,Fundamentals ofAnalytical Toxicology is an invaluable resource for thosestarting out in a career in analytical toxicology across a widerange of disciplines including clinical and forensic science, foodsafety, and pharmaceutical development. Praise from the reviews: “This is an ambitious effort to describe in detail themany and varied aspects of the science of toxicological analysis.The 17 chapters cover every foreseeable aspect, from specimencollection through analytical techniques and quality control topharmacological principles and interpretation of results. Theauthors bring together a great deal of experience in the field andhave succeeded admirably in achieving their goal: "to giveprinciples and practical information on the analysis of drugs,poisons and other relevant analytes in biological specimens...".The book is very readable and quite up-to-date, and contains manyillustrative figures, charts and tables. Both the student and thepracticing professional would do well to study this materialcarefully, as there is something here for every conceivable levelof interest.” Review from RandallBaselt "This text comes highly recommended for any analyticaltoxicology trainee." The Bulletin of the Royal College ofPathologists “Overall, this book provides a comprehensive, thorough,clear, up to date and practical treatment of analytical toxicologyat a high standard. Understanding of the text is enhanced bythe use of many illustrations. Specifications, guidelines,and methods are highlighted in grey background“Boxes”. The many and up to date literaturereferences in each chapter demonstrate the authors’ thoroughwork and permit easy access to deeper information. Thereforethis book can be highly recommended as a valuable source ofknowledge in analytical toxicology both as an introduction and forthe advanced reader.” GTFCh Bulletin“Toxichem + Krimtech”, May 2008 (translated,original review in German) “Many toxicologists will add this important referenceto their libraries because it competently fills a need...” International Journal of Toxicology “The book is very well illustrated, easy to understandand pleasant to read, and contains a wealth of dedicatedinformation.” International Journal of EnvironmentalAnalytical Chemistry
Since 1898, when Tigerstadt and Bergman first extracted renin from rabbit kidney, the reninrugs, Enzymes and Receptors of the Renin is designed to highlight molecular and clinical approaches to understanding the renin Chapter topics have been specifically chosen to cover selected contemporary, controversial and unresolved issues. A novel and uni
Fantasy Football has quickly become a multi-billion dollar industry! Finally, for the millions of fantasy footballers who play for fun and/or money, here is a serious, comprehensive guide that teaches fantasy football from its basic terminology and fundamentals to the advanced strategies and systems needed to win consistently. In Drafting To Win: The Ultimate Guide To Fantasy Football, author Robert Zarzycki finally reveals how he uses his unmatched psychological, mathematical, and football knowledge to draft players and make a long-term profit in one of today’s fastest growing hobbies. Learn How To: Select a league Rank Players Project Statistics Apply static and dynamic value-based drafting Strategize for every single round Handle being “on the clock” Significantly increase your overall chances of winning Book Quotes: "Robert''s indisputable record of success in high-stakes competition makes DRAFTING TO WIN a must-read for all serious Fantasy players." – Bob Harris, TFL Report “Robert''s accomplishments in the World Championship of Fantasy Football are unparalleled. His back-to-back finishes in the top three demonstrate his cunning understanding of how to win." -- Roger Craig, three-time Super Bowl Champion, San Francisco 49ers
With the increased use of alternative irrigation water sources on turfgrass and landscape sites, their management is becoming more complex and whole ecosystems-oriented. Yet few turfgrass managers have received formal training in the intricacies of irrigation water. Turfgrass and Landscape Irrigation Water Quality: Assessment and Management provide
Mormonism: A Guide for the Perplexed explains central facets of the Mormon faith and way of life for those wishing to gain a clearer understanding of this rapidly growing world religion. As The Church of Jesus Christ of Latter-day Saints continues to grow in the United States and especially in other countries (with a total membership of over 15 million, more than 50% of which is outside the US), and as theologians and church leaders wrestle with whether Mormonism is in fact a valid expression of modern Christianity, this distinctive religious tradition has become increasingly an object of interest and inquiry. This book is the ideal companion to the study of this perplexing and often misunderstood religion. Covering historical aspects, this guide takes a careful look at the whole of Mormonism, its tenets and practices, as well as providing an insight into a Mormon life.
Herein is a story of nine generations of Callahams beginning in Old 96 District, later Pendleton Co. SC. John and Mary (Stinson?) Callaham produced seven or eight children in Pendleton Co. Their John Jr. and Elizabeth (Dobbins) migrated to Jennings Co., IN. Later John & Eliz. migrated again to Cass Co, IN. Elizabeth gave birth to 11 children in IN. Seven remained nearby in Cass and Fulton Counties. Four children migrated. Lucinda ended in Ohio. Their two youngest sons-Alexander Washington and Andrew Morton-settled in Topeka, KS. Robert Crowe, while farming in Kansas, enlisted in the Civil War. He and his wife Jane (Thompson) produced seven sons. Chapters tell about those sons. Three sons migrated West. William Robert to WA. James Pressley & Charlie Independence to CA. Author's genealogical research into his lineage and lineages of Other Callahams in SC and VA is in appendices.
Iron is of fundamental importance for the growth, development and well being of almost all living organisms. Multiple biological systems have been developed for the uptake, utilisation, storage and homeostasis of iron in microbes, plants and mammals. e.g. Both iron deficiency and iron overload are found extensively in man: the intimate links between iron and oxidative stress are associated with a wide range of pathologies; iron has a well established role in infections by a wide range of microorganisms and parasites; there is a close link between iron requirements and cellular division with implications for cancers and other metals such as copper and zinc are closely linked with iron metabolism. The first edition of this book was published in 1991. Since then the extensive impact of molecular cell biology on the field of iron biochemistry has opened new horizons in our understanding of the transport and storage of iron and of its homeostasis. The explosive use of molecular biological techniques applied to cellular biology of iron metabolism has resulted in a rapid expansion in the literature which has led to the need for this second edition. This second edition also: Introduces many illustrations and colour photos to make the basic concepts far clearer Includes new chapters on iron and cell division and interactions of iron with other metals - particularly copper and zinc Provides additional anecdotes Incorporates an extensive and up-to-date bibliography
This is the first volume in a 4-volume set, which is the culmination of two decades of research and writing. For the first time, the natural history, migration patterns, habitat requirements, reproductive biology, and distribution of the province's birdlife are combined in one publication. This is a reprint of the original volume published in 1990 by the Royal British Columbia Museum and the Canadian Wildlife Service. No changes or updates in content have been made from the original edition.
Glaucoma affects 1% of the population over the age of 40. It is important that the practicing clinician and surgeon recognize both primary and secondary glaucoma and cases associated with other disorders. This lavishly illustrated text is authoritative and presents the reader with the whole spectrum of the disease. The book is divided into three ma
In this first outing of a new short story series by Staff Sergeant Robert Evans, Sergeant O'Quinn finds himself battling in an underground mixed martial arts fight in Iraq. Is the fight really just two men battling, or is it a setup for something far more dangerous for the American soldiers involved?
Drawing on both Christian and Latter-day Saint documents, Robert Millet clearly explains the many beliefs that Mormons hold in common with traditional Christians and also highlights differences where they exist.
Robert A. Slade, after collecting old fishing tackle since 1958 and contributing articles on old fishing lures for a collector magazine for several years started researching and writing books in the 1990's. He published the HISTORY & COLLECTIBLE FISHING TACKLE OF WISCONSIN in 1999 which sold 4,500 copies. Bob realized that even though there have been many books published on the subject of old fishing lures that few books covered any detailed history on the old lure makers. His latest book writing project was nine years in the making and covers over 100 years of lure making history starting in 1875 and covers over 2,500 lures makers throughout all of North America. THE ENCYCLOPEDIA OF OLD FISHING LURES MADE IN NORTH AMERICA is the first publication with extensive history and patent information on old lure makers and the first to include extensive coverage on Canadian lure makers. The author traveled to 11 states and 3 Candian Providences visting collectors homes, newspaper archives, museums and other sources and has taken over 10,000 pictures in preparing the historical stories for these books. The set of books arranges for the individual and company lures makers to appear in alphabetical order. People purchasing these books can buy any one single book, a whole set, or even a book a month if they desire as the books will be printed and shipped on demand. Each book has over 400 pages of text, pictures and collector values with each book containing a table of contents and index as well as a master index for the complete set of books.
This will help us customize your experience to showcase the most relevant content to your age group
Please select from below
Login
Not registered?
Sign up
Already registered?
Success – Your message will goes here
We'd love to hear from you!
Thank you for visiting our website. Would you like to provide feedback on how we could improve your experience?
This site does not use any third party cookies with one exception — it uses cookies from Google to deliver its services and to analyze traffic.Learn More.