Suddenly I couldn't breathe. I was paralyzed from the waist down with acute poliomyelitis and I now feared my diaphragms were affected. The doctors at the rehabilitation center specializing in this nationwide epidemic had already warned my parents I would never walk, even though I felt some sensation coming back in my right leg. I could hear the muffled mechanical sounds from the next ward. In the adjoining room were the "iron lungs" for completely paralyzed children to assist with their respiration in hopes they would recover the ability to inhale before they expired. The boys I saw sent to the respirator room never came back. I knew my next stop was the dreaded "death ward". I was for years old and worried I would not live to be five.
The Facts of Prostate Cancer 2/3 of men over age 50 have low grade tumors or potential cancer cells in their prostate. Only 10% will develop clinically aggressive prostate cancer. These non-invasive exams tell if a tumor is aggressive or not with an accuracy exceeding traditional biopsy results and correlate well with prognosis according to the latest international cancer conferences. The PSA test has a poor correlation with cancer detection. The digital rectal exam is more accurate in detecting high grade tumors than the PSA level. Biopsies are random, invasive and may spread tumor cells. New non-invasive treatments are guided by advanced radiologic imaging technologies. The therapeutic effect is serially studied by MRI and 3-D sonography. While generally successful, interval exams may document an unsatisfactory response, allowing "standard" treatments to be started, if necessary, in a timely manner.
Almost all branches of chemistry and material science now interface with organometallic chemistry-the study of compounds containing carbon-metal bonds. Organometallic compounds range from species which are so reactive that they only have a transient existence at ambient temperatures to species which are thermally very stable. This widely acclaimed serial contains authoritative reviews that address all aspects of organometallic chemistry, a field which has expanded enormously since the publication of Volume 1 in 1964.
Medical ethics changed dramatically in the past 30 years because physicians and humanists actively engaged each other in discussions that sometimes led to confrontation and controversy, but usually have improved the quality of medical decision-making. Before then, medical ethics had been isolated for almost two centuries from the larger philosophical, social, and religious controversies of the time. Only in the past three decades has the dialogue resumed as physicians turned to humanists for help just when humanists wanted their work to be relevant to real-life social problems. The book tells the critical story of how the breakdown in communication between physicians and humanists occurred and how it was repaired when new developments in medicine together with a social revolution forced the leaders of these two fields to resume their dialogue.
MRI Atlas of Prostate Cancer analyses high-resolution MRI scanning and dynamic contrast-enhanced (DCE) MRI. This combination improves the diagnosis and staging of prostate cancer and may soon replace PSA testing and digital rectal examination. The first two chapters focus on normal anatomy, anatomic variations, benign disease and intraprostatic tumors. The subsequent chapters on MRI of extracapsular disease create a useful atlas of pathologic anatomy. This is the first text of its kind to show color-coded DCE-MRI scans of prostate cancer and to correlate these imaging findings with tumor grading. The chapters on the post-treatment prostate clearly display the increasing incidence of post-therapy recurrences. This book is intended for internists, radiologists, radiotherapists, oncologists, urologists, family practitioners, and general surgeons. Ultrasound, MRI, and radiotherapy technicians will find it extremely useful as a reference guide.
This volume reviews recent developments in our understanding of che~ ical signaling in vertebrates. After sections dealing with general princi ples and chemical aspects of vertebrate pheromones, it follows a taxonomic approach, progressing from fish to. mammals. The editors asked a diverse, international group of leading investigators, working on a wide array of vertebrate taxa and specific issues, to consider their efforts from compar ative, evolutionary, and ecological viewpoints. The relative number of manuscripts in each part does not necessarily reflect current intensity of research, since the editors invited speakers who together would provide a balanced and comprehensive overview, while avoiding duplication. Still, the part on mammals is the longest. Fourth in a series dating from 1977, this volume illuminates current trends and likely future developments in the field of chemical signaling in vertebrates. Going back even farther, the first chapter, a personal account of the past quarter century by Dr. Mykytowycz recalls the most important milestones, such as symposia, or the founding of societies and journals. He also credits those investigators who stand out by their seminal studies.
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