You too can follow in the steps of the great astronomers such as Hipparchus, Galileo, Kepler and Hubble, who all contributed so much to our modern understanding of the cosmos. This book gives the student or amateur astronomer the following tools to replicate some of these seminal observations from their own homes: With your own eyes: Use your own observations and measurements to discover and confirm the phenomena of the seasons, the analemma and the equation of time, the logic behind celestial coordinates, and even the precession of the equinoxes. With a consumer-grade digital camera: Record the changing brightness of an eclipsing binary star and show that a pulsating star changes color as it brightens and dims. Add an inexpensive diffraction grating to your camera and see the variety of spectral features in the stars, and demonstrate that the Sun’s spectrum is similar to one particular type of stellar spectrum. With a backyard telescope: Add a CCD imager and you can measure the scale of the Solar System and the distance to a nearby star. You could even measure the distance to another galaxy and observe the cosmological redshift of the expanding universe. Astronomical Discoveries You Can Make, Too! doesn’t just tell you about the development of astronomy; it shows you how to discover for yourself the essential features of the universe.
For the experienced amateur astronomer who is wondering if there is something useful, valuable, and permanent that can be done with his or her observational skills, the answer is, “Yes, there is!” This is THE book for the amateur astronomer who is ready to take the next step in his or her astronomical journey. Till now there has been no text that points curious amateur astronomers to the research possibilities open to them. At the 2006 meeting of the Society for Astronomical Sciences, participants agreed that the lack of such a text was a serious gap in the astronomical book market. This book plugs that hole.
Complex and unexplained phenomena tend to foster unorthodox perspectives. This publication is an example, as is a prior publication that emphasized the concept that intermediary metabolism might play a significant and determining role in hepatocyte proliferation and 1 tumorigenesis. Formulation of this hypothesis was based on an attempt to clarify several poorly understood phenomena; including the observations: 1) that xenobiotic peroxisome proliferators such as the fibrate hypolipidemic agents induce hepatocyte proliferation and carcinogenesis in rodents; 2) that benign and malignant liver tumors complicate the human syndrome of glycogen storage disease type I (glucose-6-phosphatase deficiency); and 3) that in this same syndrome, administration of glucose exerts an anti-tumor effect. Fatty acid and glucose metabolism are tightly linked in a we- established and profoundly inportant interplay. This connection, together with the fact that peroxisome proliferator-induced hepatocyte proliferation and carcinogenesis reflects inhibition of mitochondrial carnitine palmitoyltransferase-I and fatty acid oxidation, suggested the possibility that regulation of fatty acid metabolism could prove to be a pivotal determinant in the control of cell growth. In 1993, the year in which the paper cited above was published, insight into the importance of growth factors and signal transduction pathways in cell cycle regulation was increasing rapidly, but metabolic and energetic aspects of cell proliferation had attracted relatively little attention. Despite this, the concept seemed inescapable that the two seemingly distinct and unrelated determinants — signal transduction and metabolism — were integrally linked.
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