DIVRethinks constitutional jurisprudence from a postmodern perspective, attempting to integrate a Kuhnian approach to intellectual transformations with a Rawlsian pragmatic approach to decision making./div
Originally published in 2004. Examining the successes and failures of three decades of environmental law, this absorbing book reconsiders some of the policies devised to remedy centuries of abuse of the planet. It acknowledges the advances made using technological standards to effect pollution control as well as rudimentary systems that regulate use of land at the local level. However, as the author observes, these systems have limitations in solving vexing problems such as sprawl and non-point source pollution, as the cost of their use can easily outweigh the benefits. He suggests a system, termed 'Green Wood in the Bundle of Sticks', that provides the necessary theoretical and historical bases to bridge the gap between the potentials of each system. Using objective criteria based on science, this system is tied to a land ownership system that also takes into account societal concerns at a broader level.
Serving to bridge the gap between differing approaches to psychology, this new text provides some of the most compelling evidence yet for the subjective presence and objective efficacy of the mental image. In this day and age of "dissociation" between physiological psychologists and other psychologists, between cognitive scientist and mentalist, between researchers and practitioners, mental imagery and its psychophysiology pose some intellectually "sticky" problems - and some promising resolutions - that should bind together differing disciplines within psychology.
This book comprehensively describes the development and practice of DNA-encoded library synthesis technology. Together, the chapters detail an approach to drug discovery that offers an attractive addition to the portfolio of existing hit generation technologies such as high-throughput screening, structure-based drug discovery and fragment-based screening. The book: Provides a valuable guide for understanding and applying DNA-encoded combinatorial chemistry Helps chemists generate and screen novel chemical libraries of large size and quality Bridges interdisciplinary areas of DNA-encoded combinatorial chemistry – synthetic and analytical chemistry, molecular biology, informatics, and biochemistry Shows medicinal and pharmaceutical chemists how to efficiently broaden available "chemical space" for drug discovery Provides expert and up-to-date summary of reported literature for DNA-encoded and DNA-directed chemistry technology and methods
An Introduction to the Standard Model of Particle Physics familiarizes readers with what is considered tested and accepted and in so doing, gives them a grounding in particle physics in general. Whenever possible, Dr. Mann takes an historical approach showing how the model is linked to the physics that most of us have learned in less challenging areas. Dr. Mann reviews special relativity and classical mechanics, symmetries, conservation laws, and particle classification; then working from the tested paradigm of the model itself, he: Describes the Standard Model in terms of its electromagnetic, strong, and weak components Explores the experimental tools and methods of particle physics Introduces Feynman diagrams, wave equations, and gauge invariance, building up to the theory of Quantum Electrodynamics Describes the theories of the Strong and Electroweak interactions Uncovers frontier areas and explores what might lie beyond our current concepts of the subatomic world Those who work through the material will develop a solid command of the basics of particle physics. The book does require a knowledge of special relativity, quantum mechanics, and electromagnetism, but most importantly it requires a hunger to understand at the most fundamental level: why things exist and how it is that anything happens. This book will prepare students and others for further study, but most importantly it will prepare them to open their minds to the mysteries that lie ahead. Ultimately, the Large Hadron Collider may prove the model correct, helping so many realize their greatest dreams ... or it might poke holes in the model, leaving us to wonder an even more exciting possibility: that the answers lie in possibilities so unique that we have not even dreamt of them.
Examines the desegregation experience, with a focus on the impact of the Supreme Court's decisions from Brown v. Board of Education in 1954, through Parents Involved v. Seattle School District in 2007. Assesses desegregation in Delaware, one of the states involved in the original Brown litigation"--Provided by publisher.
Anyone who has sat on a jury or followed a high-profile trial on television usually comes to the realization that a trial, particularly a criminal trial, is really a performance. Verdicts seem determined as much by which lawyer can best connect with the hearts and minds of the jurors as by what the evidence might suggest. In this celebration of the American trial as a great cultural achievement, Robert Burns, a trial lawyer and a trained philosopher, explores how these legal proceedings bring about justice. The trial, he reminds us, is not confined to the impartial application of legal rules to factual findings. Burns depicts the trial as an institution employing its own language and styles of performance that elevate the understanding of decision-makers, bringing them in contact with moral sources beyond the limits of law. Burns explores the rich narrative structure of the trial, beginning with the lawyers' opening statements, which establish opposing moral frameworks in which to interpret the evidence. In the succession of witnesses, stories compete and are held in tension. At some point during the performance, a sense of the right thing to do arises among the jurors. How this happens is at the core of Burns's investigation, which draws on careful descriptions of what trial lawyers do, the rules governing their actions, interpretations of actual trial material, social science findings, and a broad philosophical and political appreciation of the trial as a unique vehicle of American self-government.
Structured introduction covers everything the engineer needs to know: nature of fluids, hydrostatics, differential and integral relations, dimensional analysis, viscous flows, more. Solutions to selected problems. 760 illustrations. 1985 edition.
A fully updated and expanded edition of the bestselling guide on toxicology and its practical application • Covers the diverse chemical hazards encountered in the modern work and natural environment, and provides a practical understanding of these hazards • New chapters cover the emerging areas of toxicology such as omics, computational toxicology, and nanotoxicology • Provides clear explanations and practical understanding of the fundamentals necessary for an understanding of the effects of chemical hazards on human health and ecosystems • Includes case histories and examples from industry demonstrate the application of toxicological principles • Supplemented with numerous illustrations to clarify and summarize key points, annotated bibliographies, and a comprehensive glossary of toxicological terms
This is a self-contained introduction to the theory of information and coding. It can be used either for self-study or as the basis for a course at either the graduate or ,undergraduate level. The text includes dozens of worked examples and several hundred problems for solution.
Robert Eugene Marshak (1916-92) devoted much of his life to helping other people carry out scientific research and gather to discuss their work. In addition to his scientific statesmanship, he was an extraordinarily gifted research scientist, and many of his scientific contributions have been prophetic. This book pays homage to his creativity and continuing work, with contributions from many of the people whose lives have been influenced by him.
Chronic Gastritis and Hypochlorhydria in the Elderly provides the most current and comprehensive treatment of atrophic gastritis available. The latest theories on the pathogenesis of atrophic gastritis are examined, focusing on topics such as epidemiology and the relationship between atrophic gastritis and helicobacter pylori infection. The relationship among cell proliferation, differentiation, and gastric cancer is covered as well. The book also reviews new material on nutrient and drug bioavailability in atrophic gastritis. Chronic Gastritis and Hypochlorhydria in the Elderly will benefit gerontologists, gastroenterologists, and clinical microbiologists treating large numbers of elderly patients. It will also serve as a reference text for medical and nutritional students.
Adenomatous Polyps of the Colon: Pathobiological and Clinical Features consolidates the vast body of basic science and clinical data associated with adenomatous polyps of the colon, much of it inspired by the realization that most colorectal carcinomas seem to arise in such polyps. This book strives to evaluate these data, with particular emphasis on their implications for management of polyp-bearing subjects. Topics comprehensively explored include anatomy and histology of the normal colon; pathologic characteristics of adenomatous polyps, differential diagnosis, and grading schemes for degree of dysplasia and villosity; adenomatous polyposes; histologic and epidemiologic evidence for the malignant potential of adenomatous polyps; and detection and management, with special attention to endoscopy, endoscopic polypectomy, the malignant polyp, and post-polypectomy surveillance schedules.
This widely acclaimed book is a complete, authoritative reference on nutrition and its role in contemporary medicine, dietetics, nursing, public health, and public policy. Distinguished international experts provide in-depth information on historical landmarks in nutrition, specific dietary components, nutrition in integrated biologic systems, nutritional assessment through the life cycle, nutrition in various clinical disorders, and public health and policy issues. Modern Nutrition in Health and Disease, Eleventh Edition, offers coverage of nutrition's role in disease prevention, international nutrition issues, public health concerns, the role of obesity in a variety of chronic illnesses, genetics as it applies to nutrition, and areas of major scientific progress relating nutrition to disease.
Radiation Pathology is an up-to-date compendium of the effects of ionizing radiation on human tissues. It will be of great value to radiation oncologists, pathologists, and other professionals. The early chapters deal with basic science: physics, radiobiology, genetics, etc. The circumstances of human exposures (therapeutic, accidental, warfare) are then considered in the light of extensive epidemiological data. Acute radiation syndromes and radiation cardiogenesis are described in detail, including recent information on mechanisms of oncogenesis. For the benefit of readers who are not radiation oncologists, two chapters outline the current uses of radiation in therapy and in diagnosis, including the various applications of radionuclides. The bulk of the text deals with radiopathology and its morphologic expression. An overview orients the reader and classifies the main types of lesions. The chapters on specific organs or organ systems are consistently divided into sections to facilitate rapid retrieval of information on: normal structure, tolerance doses, experimental studies, morphology and pathogenesis, and clinical manifestations. The authors' lucid, well-organized descriptions will inform radiation oncologists about the types of injury to be expected, and will guide pathologists in making differential diagnoses.
Concise and easy to navigate, Clinical Handbook of Nephrology contains vital, everyday information on renal physiology and a wide range of topics, including diagnosis and treatment of acute and chronic kidney diseases, hypertension, electrolyte and acid-base disorders, dialysis, and kidney transplantation. This fully up-to-date reference (formerly Nephrology Pocket, a textbook originally published by Börm Bruckmeier) is ideal for physicians, nurses, dialysis center staff, medical students, and trainees, offering a practical roadmap for managing the renal disorders most likely to be encountered in clinical practice. - Contains dozens of diagnostic and treatment algorithms, tables, and charts that allow you to find answers quickly and easily at the point of care. - Allows you to easily find protocols, drug information and treatment guidelines, including the latest KDIGO (Kidney Disease Improving Global Outcomes) for the evaluation and management of chronic kidney disease, glomerulonephritis, and blood pressure management. - Provides sections on symptoms, signs, and differential diagnoses that allow you to quickly identify common differentials. - Features dedicated chapters on kidney stones, dialysis, and kidney transplantation. - Includes common labs useful for ruling out other medical causes of renal disorders.
Written by an eminent authority on interviewing techniques and resident training, Patient-Centered Interviewing: An Evidence-Based Method provides practical, how-to guidance on every aspect of physician-patient communication. Readers will hone their skills in patient-centered interviewing techniques whose effectiveness is documented by published evidence.Chapters present techniques for defining the patient's symptoms, making the doctor-centered part of the interviewing process patient-friendly, and handling specific scenarios. Also included are effective strategies for summarizing data from the interview, presenting these findings to colleagues, and using patient education materials. The book's user-friendly design features icons, boxed case vignettes, and use of color to highlight key points.
The field of counseling and psychotherapy has for years presented the puzzling spectacle of unabating enthusiasm for forms of treatment whose effectiveness cannot be objectively demonstrated. With few exceptions, statistical studies have consistently failed to show that any form of psychotherapy is followed by significantly more improvement than would be caused by the mere passage of an equivalent period of time. Despite this, practitioners of various psychotherapeutic schools have remained firmly convinced that their methods are effective. Many recipients of these forms of treatment also believe that they are being helped. The series of investigations reported in this impressive book resolve this paradoxical state of affairs. The investigators have overcome two major obstacles to progress in the past--lack of agreement on measures of improvement and difficulty of measuring active ingredients of the psychotherapy relationship. The inability of therapists of different theoretical persuasions to agree on criteria of improvement has made comparison of the results of different forms of treatment nearly impossible. The authors have solved this intractable problem by using a wide range of improvement measures and showing that, regardless of measures used in different studies, a significantly higher proportion of results favor their hypothesis than disregard it. Overall, this book represented a major advance at the time of its original publication and is of continuing importance. The research findings resolve some of the most stubborn research problems in psychotherapy, and the training program based on them points the way toward overcoming the shortage of psychotherapists.
At the beginning of the new millennium, it is opportune to raveling of the molecular pathways of impaired host - review what has been accomplished in the field of infec- fense mechanisms and the characterization of the genetic tious diseases during the last decades of the previous mutations involved, with the prospect of novel strategies century. The paradigm of the immunocompromised host for therapeutic interventions and possible corrective gene has taught much about the pathophysiology of infectious therapy. In this foreword, I will take a helicopter view of diseases, particularly with regard to immunological as- the various aspects of host defense mechanisms with pects of host defense. In the beginning, Robert Good special emphasis on genetic factors, because of their re- called immunodeficiency syndromes “experiments of na- vance for the course and outcome of infections. ture. ” In the 1960s and subsequent decades, the clinical During life, there exist phases of age-related c- and immunological aspects of immune deficiencies were promised immune functions. After birth there is a phys- studied and adequate treatment attempted. A reflection of logical immune deficiency because the production of an- these developments were the three successful meetings on bodies commences slowly upon contact of the neonate these topics in Veldhoven, The Netherlands (1980), Stir- with microorganisms and upon vaccination.
Features a comprehensive summary of the chemical, physiological, and nutritional relationships of all recognized vitamins! Maintaining the standards of excellence set forth in the previous editions, the Handbook of Vitamins, Third Edition presents a thorough examination of the fundamental characteristics, functions, and roles of vitamins in human health. Extensively updated and expanded to reflect the latest advances in analytical and separation methodologies! Offering a compendium of authoritative, current knowledge on the nature and function of each known nutrient, the Third Edition discusses.... improvements in the methodology, isolation, identification, and the synthesis of vitamins the chemistry, metabolism, and biochemical functions of vitamins vitamin interactions with environmental factors, drugs, alcohol, and smoking vitamins in disease prevention and health promotion the efficacy and hazards of high vitamin dosages and more! New sections cover... the roles vitamins play as catalysts, cellular regulators, and co-substrates biochemical markers for vitamin deficiency and groups at risk the relationship of B12 and folate metabolism to homocysteine regulation, and the possible connections of homocysteine to vascular diseases and developmental defects new roles for vitamins A, K, and D, and the role of vitamin E and flavonoids in oxidant defense Containing over 2800 literature references and 150 illustrations and tables, the Handbook of Vitamins, Third Edition serves as an indisputably valuable reference for human and animal nutritionists, dietitians, food scientists and technologists, biochemists, organic and analytical chemists, pharmacologists, toxicologists, physiologists, physicians in general practice, and makes an indispensable text for upper-level undergraduate and graduate students in these disciplines.
This text introduces upper-level undergraduates to Lie group theory and physical applications. It further illustrates Lie group theory's role in several fields of physics. 1974 edition. Includes 75 figures and 17 tables, exercises and problems.
This 8th Edition of Moss and Adams' Heart Disease in Infants, Children, and Adolescents: Including the Fetus and Young Adult, provides updated and useful information from leading experts in pediatric cardiology. Added chapters and a companion web site that includes the full text with bonus question and answer sections make this Moss and Adams’ edition a valuable resource for those who care for infants, children, adolescents, young adults, and fetuses with heart disease. Features: · Access to online questions similar to those on the pediatric cardiology board examination to prepare you for certification or recertification · Leading international experts provide state-of-the-art diagnostic and interventional techniques to keep you abreast of the latest advances in treatment of young patients · Chapters on quality of life, quality and safety, pharmacology, and research design add to this well-respected text
This advanced-level treatment describes the mathematics of catastrophe theory and its applications to problems in mathematics, physics, chemistry and engineering. 28 tables. 397 black-and-white illustrations. 1981 edition.
DIVRethinks constitutional jurisprudence from a postmodern perspective, attempting to integrate a Kuhnian approach to intellectual transformations with a Rawlsian pragmatic approach to decision making./div
This classic book provides a straightforward approach to the diagnosis and management of the dizzy patient. The purpose of this thoroughly revised and updated edition is to provide a framework for understanding the pathophysiology of diseases involving the vestibular system. The revision includes a systematic evaluation of the dizzy patient, diagnosis and management of common neurotological disorders, and a new section on symptomatic management of vertigo.
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