After more than 75 years, Nelson Textbook of Pediatrics remains your indispensable source for definitive, state-of-the-art answers on every aspect of pediatric care. Embracing the new advances in science as well as the time-honored art of pediatric practice, this classic reference provides the essential information that practitioners and other care providers involved in pediatric health care throughout the world need to understand to effectively address the enormous range of biologic, psychologic, and social problems that our children and youth may face. Brand-new chapters and comprehensive revisions throughout ensure that you have the most recent information on diagnosis and treatment of pediatric diseases based on the latest recommendations and methodologies. "The coverage of such a wide range of subjects relating to child health makes this textbook still the gold standard and companion for all pediatricians across the world." Reviewed by Neel Kamal, Sept 2015 "All in all, this is an excellent and detailed paediatric review textbook which represents excellent value for money..truly a textbook for the global community" Reviewed by glycosmedia.com, Sept 2015 Form a definitive diagnosis and create the best treatment plans possible using evidence-based medicine and astute clinical experiences from leading international authors-many new to this edition. A NEW two-volume layout provides superior portability and exceptional ease of use. Gain a more complete perspective. Along with a broader emphasis on imaging and molecular diagnoses and updated references, the new edition includes an increased focus on international issues to ensure relevance in pediatrics practice throughout the world. Effectively apply the latest techniques and approaches with complete updates throughout 35 new chapters, including: Innovations in Addressing Child Health and Survival in Low Income Settings; Developmental Domains and Theories of Cognition; The Reggio Emilia Educational Approach Catatonia ; Refeeding Syndrome; Altitude-associated Illness; Genetic Approaches to Rare and Undiagnosed Diseases; Healthcare?Associated Infections; Intrapartum and Peripartum Infections; Bath salts and other drugs of abuse; Small Fiber Polyneuropathy; Microbiome; Kingella kingae; Mitochondrial Neurogastrointestinal Encephalomyopathy; Nonalcoholic Fatty Liver Disease; Plagiocephaly; CNS Vasculitis; Anterior Cruciate Ligament Rupture; and Sports-Related Traumatic Brain Injury. Recognize, diagnose, and manage genetic and acquired conditions more effectively. A new Rehabilitation section with 10 new chapters, including: Evaluation of the Child for Rehabilitative Services; Severe Traumatic Brain Injury; Spinal Cord Injury and Autonomic Crisis Management; Spasticity; Birth Brachial Plexus Palsy; Traumatic and Sports-Related Injuries; Meningomyelocele; Health and Wellness for Children with Disabilities. Manage the transition to adult healthcare for children with chronic diseases through discussions of the overall health needs of patients with congenital heart defects, diabetes, and cystic fibrosis. Understand the principles of therapy and which drugs and dosages to prescribe for every disease. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
One of the main causes of failure in the treatment of cancer is the development of drug resistance by the cancer cells. The design of cancer chemotherapy has become increasingly sophisticated, yet there is no cancer treatment that is 100 percent effective against disseminated cancer. Resistance to treatment with anticancer drugs results from a variety of factors including individual variations in patients and somatic cell genetic differences in tumours, even those from the same tissue of origin. Frequently resistance is intrinsic to the cancer, but as therapy becomes more and more effective, acquired resistance has also become common.The most common reason for acquisition of resistance to a broad range of anticancer drugs is expression of one or more energy-dependent transporters that detect and eject anti-cancer drugs from cells, but other mechanisms of resistance including insensitivity to drug-induced apoptosis and induction of drug-detoxifying mechanisms probably play an important role in acquired anticancer drug resistance. Studies on mechanisms of cancer drug resistance have yielded important information on how to circumvent this resistance to improve cancer chemotherapy and have implications for pharmacokinetics of many commonly used drugs.
With an editorial team of leading experts from the American College of Emergency Physicians and the American Heart Association, this book is the first complete, clinically oriented reference textbook in emergency cardiovascular care and CPR. The book translates bench research to the clinician's bedside needs and addresses end-of-life issues. The content is appropriate for a large audience including early caregivers, emergency department and CCU nurses, students, residents, fellows, and hospitalists responsible for cardiovascular emergency situations. A companion Website will include the fully searchable text, instructional videos produced by the AHA, and links to ACC, AHA, ASE, ACEP, and ILCOR guidelines and policy statements.
What is the church? What is its mission in the world? Modern Protestantism's inability to provide a clear answer to these seemingly simple questions has resulted in vast confusion amongst pastors about the nature of their calling and has left congregations languishing without a clear reason for existence. Many of the voices and allegiances competing for the churches' attention have rushed in to fill the void, with the result that the church in modernity has frequently found itself captive to the prevailing culture. Yet from within the belly of highly culturally accommodated churches, both the German pastor-theologian Dietrich Bonhoeffer and the American theological ethicist Stanley Hauerwas were able to articulate compelling visions of churches freed from their cultural captivity in order to truly and freely serve God and neighbor. Against the complex and confusing backdrops of Nazi Germany and late twentieth- and early twenty-first-century America respectively, Bonhoeffer and Hauerwas sought to recover the ethical and political character of the Christian faith through recalling the church back to the christological center of its faith. Together they provide a rich set of complementary, and at times mutually correcting, resources for the contemporary church as it seeks to faithfully bear witness to Christ amidst the ruins of Christendom.
Yen Jaffe's Reproductive Endocrinology helps you successfully diagnose and manage the spectrum of female and male reproductive system diseases, from impaired fertility, infertility, and recurrent pregnancy loss through problems of sexual development, puberty, menstrual disturbances, fibroids, endometriosis, and reproductive aging. This trusted endocrinology reference book is ideal for fellows, endocrinologists, or as a quick reference when making daily diagnostic and therapeutic decisions. It is just the resource you need to offer your patients the best possible reproductive care. "This new edition helps the reader to stay on top of recent developments. It is a must for subspecialists in reproductive medicine and a valuable source of information in the library of any department and clinical unit involved in reproductive medicine." Reviewed by Acta Obstetricia et Gynecologica Scandinavica February 2015 "It is a must for subspecialists in reproductive medicine and a valuable source of information in the library of any department and clinical unit involved in reproductive medicine." Reviewed by Acta Obstetricia et Gynecologica Scandinavica , March 2015 Get unmatched guidance you can trust, such as fresh insights into today's field and future advances, through the knowledge gleaned from worldwide fertility experts in reproductive medicine. Further your study of Reproductive Endocrinology with a list of suggested readings at the end of each chapter. Conveniently access the fully searchable text and view all of the images online at Expert Consult. Apply the latest reproductive endocrinology advances in basic and clinical science, including molecular, cellular, and genetic concepts, and grasp their relevance to pathophysiology, diagnosis, and therapy. Maximize fertility in women and men undergoing chemotherapy and other cancer treatments, and counsel patients on environmental factors affecting reproduction. Stay on top of recent developments including the impact of obesity on fertility; ovarian tissue banking; cryopreservation; pre-implantation genetic diagnosis; ovulation induction; and risks and treatments for steroid hormone-responsive cancers. View basic anatomic structures, endocrine processes, and cell function and dysfunction with absolute clarity through full-color illustrations and new images throughout. Confidently perform procedures through expanded coverage of reproductive and infertility surgery and online videos demonstrating key techniques.
If you are passionate about participating in the recovery of preaching for the spiritual formation of God's people, then you will want to jump into this lively collection of biblically rigorous, culturally intuitive, grace-drenched sermons. Robert Dean sets the bar very high, even as he throws the gauntlet down, with these remarkable expressions of all that preaching was supposed to be and can still become. Animated by the conviction that the preached word is the playground of the Living Word, the pages of Leaps of Faith are populated by saints and sinners, pimps and prophets. Unexpectedly and delightfully, Bono works alongside Bonhoeffer, Dr. Phil learns a lesson from the Amish, and a discussion of body odor primes the senses for contemplating the mission of God. Rooted deeply in the lives of actual worshipping communities, these wonder-laden sermons from the prophetic imagination of an emerging pastor-theologian dare the reader to leap into the continuing story of the Triune God and, in doing so, discover that all of life has been taken up in the Gospel of Jesus Christ.
Long recognized as the leading text in this dynamic field, Rogers’ Textbook of Pediatric Intensive Care provides comprehensive, clear explanations of both the principles underlying pediatric critical care disease and trauma as well as how these principles are applied. Led by Drs. Donald H. Shaffner, John J. McCloskey, Elizabeth A. Hunt, and Robert C. Tasker, along with a team of 27 section editors as well as more than 250 expert global contributors, the fully revised Sixth Edition brings you completely up to date on today’s understanding, treatments, technologies, and outcomes regarding critical illness in children.
Understanding the interrelationship of business, society and government is vital to working at any level in a company of any size. This text uses a case analysis approach to explore this interrelationship in today’s high-tech global community. The authors crystallize the complex array of issues that business leaders, managers, and employees face in market and nonmarket environments, from balancing stakeholder interests and dealing with government regulations to managing crises and making socially responsible and ethical decisions. Technical concepts come to life through a variety of cases and case questions, thought-provoking personal and professional applications, ethical dilemmas, and practical exercises. Furthermore, an appendix offers approaches to case analysis and includes a case analysis table that serves as a model for students and professors. With its thorough coverage of relevant issues and skill-building elements to stimulate critical thinking, this text will prepare students to understand and confront real-world business concerns.
For over forty years Stanley Hauerwas has been writing theology that matters. In this new collection of essays, lectures, and sermons, Hauerwas continues his life's work of exploring the theological web, discovering and recovering the connections necessary for the church to bear faithful witness to Christ in our complex and changing times. Hauerwas enters into conversation with a diverse array of interlocutors as he brings new insights to bear on matters theological, delves into university matters, demonstrates how lives matter, and continues in his passionate commitment to the matter of preaching. Essays by Robert Dean illumine the connections that have made Hauerwas's theological web-slinging so significant and demonstrate why Hauerwas's sermons have a crucial role to play in the recovery of a gospel-shaped homiletical imagination.
Introduction to Environmental Forensics helps readers unravel the complexities of environmental pollution cases. It outlines techniques for identifying the source of a contaminant release, when the release occurred, and the extent of human exposure. Written by leading experts in environmental investigations, the text provides detailed information on chemical "fingerprinting" techniques applicable to ground water, soils, sediments, and air, plus an in-depth look at petroleum hydrocarbons. It gives the environmental scientist, engineer, and legal specialist a complete toolbox for conducting forensic investigations. It demonstrates the range of scientific analyses that are available to answer questions of environmental liability and support a legal argument, and provides several examples and case studies to illustrate how these methods are applied. This is a textbook that would prove useful to a range of disciplines, including environmental scientists involved in water and air pollution, contaminated land and geographical information systems; and archaeologists, hydrochemists and geochemists interested in dating sources of pollution. - Co-edited by one of the experts from the Civil Action case in Woburn, MA - Provides essential information about identifying environmental contaminants responsible for millions of deaths per year - Contains the latest information and coverage of issues crucial to both forensics investigators and environmental scientists
From scholarly journals, Trivers (anthropology and biological sciences, Rutgers U.) has selected five of his papers published between 1971 and 1976, and another five published between 1982 and 2000. He has added accounts of how they were written, and short postscripts to bring readers up to date or at least point them to more recent work on the issues discussed. Annotation (c)2003 Book News, Inc., Portland, OR (booknews.com).
This book is aimed at students in communications and signal processing who want to extend their skills in the energy area. It describes power systems and why these backgrounds are so useful to smart grid, wireless communications being very different to traditional wireline communications.
When realizing a programming language as VM, implementing behavior as part of the VM, as primitive, usually results in reduced execution times. But supporting and developing primitive functions requires more effort than maintaining and using code in the hosted language since debugging is harder, and the turn-around times for VM parts are higher. Furthermore, source artifacts of primitive functions are seldom reused in new implementations of the same language. And if they are reused, the existing API usually is emulated, reducing the performance gains. Because of recent results in tracing dynamic compilation, the trade-off between performance and ease of implementation, reuse, and changeability might now be decided adversely. In this work, we investigate the trade-offs when creating primitives, and in particular how large a difference remains between primitive and hosted function run times in VMs with tracing just-in-time compiler. To that end, we implemented the algorithmic primitive BitBlt three times for RSqueak/VM. RSqueak/VM is a Smalltalk VM utilizing the PyPy RPython toolchain. We compare primitive implementations in C, RPython, and Smalltalk, showing that due to the tracing just-in-time compiler, the performance gap has lessened by one magnitude to one magnitude.
A history of acoustics from the 19th century to the present, written by one of the pre-eminent members of the acoustical community. The book is both a review of the major scientific advances in acoustics as well as an account of famous acousticians and their discoveries, taking in the development of the Acoustical Society of America. Acoustics is distinguished by its interdisciplinary nature and the book duly explores the fields development in its relationship to other sciences. In addition to covering the history of acoustics, the book concludes with the future of acoustics. Beautifully illustrated.
In less than three decades, China has grown from playing a negligible role in international trade to being one of the world's largest exporters, a substantial importer of raw materials, intermediate outputs, and other goods, and both a recipient and source of foreign investment. Not surprisingly, China's economic dynamism has generated considerable attention and concern in the United States and beyond. While some analysts have warned of the potential pitfalls of China's rise—the loss of jobs, for example—others have highlighted the benefits of new market and investment opportunities for US firms. Bringing together an expert group of contributors, China's Growing Role in World Trade undertakes an empirical investigation of the effects of China's new status. The essays collected here provide detailed analyses of the microstructure of trade, the macroeconomic implications, sector-level issues, and foreign direct investment. This volume's careful examination of micro data in light of established economic theories clarifies a number of misconceptions, disproves some conventional wisdom, and documents data patterns that enhance our understanding of China's trade and what it may mean to the rest of the world.
Make the most effective diagnostic and therapeutic decisions quickly and efficiently! A best seller for over 25 years, The 5-Minute Clinical Consult 2019 is a practical, highly organized resource for clinicians in primary care, family medicine, emergency medicine, nursing, and pediatrics. It provides rapid access to guidance on diagnosis, treatment, medications, follow-up, and associated factors for more than 540 diseases and conditions. The 5-Minute Clinical Consult 2019 is designed to deliver maximum clinical confidence as efficiently as possible...allowing you to focus your valuable time on giving your patients the best possible care. Get quick access to all-new topics, including Advance Care Planning, Geriatric Care, and Medical Marijuana. Find the answers you need quickly thanks to an intuitive, at-a-glance format, with concise, bulleted text; hundreds of diagnostic and therapeutic algorithms; ICD-10 codes, DSM-5 criteria; and much more. Make confident decisions aided by current evidence-based designations in each topic.
This volume emphasises knowledge transfer from the lab to the field and describes collaboration technology through three lenses: Proof of Concept, Proof of Value, and Proof of Use. The contributors focus on work practices that extend collaboration into a structured form where groups can work together to solve real-world complex problems. As with the other AMIS volumes, the contributors comprise internationally known experts in the field of Information Systems. Includes online access.
This guide offers a different approach from the misleading formulae for success offered by much self-help business literature. The authors believe that in today's turbulent competitive environment, it is necessary to embrace uncertainty and set more realistic expectations.
A Special Publication of the Society of Environmental Toxicology and Chemistry (SETAC) Aquatic Mesocosm Studies in Ecological Risk Assessment discusses the methods currently used for conducting simulated field studies and provides a series of case histories in which mesocosm type studies have been used to assess the impact of pesticides on aquatic ecosystems. Specific chapters address the dosing and exposure components of such studies and how they influence experimental design. Advantages and disadvantages of various statistical designs are addressed in detail. Regulatory aspects of the design and interpretation of these studies are also covered. The book will be a superb reference for aquatic biologists, ecologists, toxicologists, environmental toxicologists, environmental chemists, and regulatory personnel.
Western Water A to Z is the first ever field guide to Western water. Reinventing this twentieth-century genre for a twenty-first-century audience, Robert R. Crifasi answers questions about rivers, water projects, the culture of water, the ecosystems water projects have created or destroyed, and the reliance of cities, farms, and industries on this critical resource. Organized as a collection of terms, the book addresses the most salient water issues and provides helpful background information regarding their origins and implications. Photographs serve a vital role in the cultural dialogue on water and stand as an equal partner to the text. Each subject is covered in about one page and is accompanied by one or two striking images from famous photographers like Margaret Bourke-White, Carleton E. Watkins, Arthur Rothstein, William Henry Jackson, and Dorothea Lang as well as Crifasi’s own work. Water often finds itself at the center of our cultural discourse in art, cinema, and literature, which play essential roles in shaping our understanding and experience of Western water. Crifasi also engages personalities that are nearly synonymous with Western water—John Wesley Powell, Elwood Mead, and Floyd Dominy, among others—to show how their lives intertwined with and often influenced the course of water development across the region. Travelers, adventurers, students, and anyone interested in water will find Western Water A to Z a handy and entertaining reference guide.
Encyclopedia of Plant and Crop Science is the first-ever single-source reference work to inclusively cover classic and modern studies in plant biology in conjunction with research, applications, and innovations in crop science and agriculture. From the fundamentals of plant growth and reproduction to developments in agronomy and agricultural science, the encyclopedia's authoritative content nurtures communication between these academically distinct yet intrinsically related fields-offering a spread of clear, descriptive, and concise entries to optimally serve scientists, agriculturalists, policy makers, students, and the general public.
Considering the history and theory of geoarchaeology, this book discusses soils and environmental interpretations; initial context and site formation; methods of discovery and spatial analyses; estimating time; and others. It is for all professionals and students interested in the field of geoarchaeology
This textbook was finalized during the worldwide COVID-19 pandemic. For years prior to the pandemic, clinical trials have shown improvement and cures of pulmonary disorders with the intravenous administration of mesenchymal stem cells. These cells are administered into the venous system, pass through the heart, and then lodge in the capillary network of the lungs where they decrease scar tissue and stimulate the regeneration of new lung tissue. The known benefits of cell therapy for pulmonary disease has been the foundation for the use of allogeneic stem cells to effectively treat (and in some cases cure) COVID-19-related lung disorders. Sadly, many of the highly qualified health care professionals caring for these critically ill patients are unfamiliar with the concept of stem cells and regenerative medicine. This unfamiliarity has resulted in patients throughout the world not receiving the benefit of these potentially life-saving treatments. The goal of this textbook is to provide a basic scientific and clinical multispecialty reference source for stem cells and regenerative medicine to be used as an extension of the American College of Regenerative Medicine.™ Chapters focus on basic science as well as the extravascular applications of regenerative medicine for all hard and soft tissues of the body including musculoskeletal and orthopedics, dental and maxillofacial surgery, and dermatology and plastic surgery. Other topics include plasma products such as PRP and PPP, tissue banking, stem cell expansion, and regulatory guidelines. It is our hope that this textbook will assist in the following areas: - Academic institutions will utilize this textbook as a reference source to educate health care professionals of the future, so that regenerative medicine is integrated into the core curriculum and foundation of medical learning. These professionals include medical doctors of all specialties, dentists and maxillofacial surgeons, veterinarians, researchers, nurses, study coordinators, physical therapists, occupational therapists, perfusionists, healthcare and life science attorneys, advocates, administrators, and policy makers. - Practicing health care professionals who have already finished their training will read this textbook with an open mind and understand more about stem cells and regenerative medicine. - To provide a foundation of accurate peer-reviewed scientific and clinical information for patient and industry advocates, as well as those involved in formulation of health care policy.
The publication of this volume completes the new edition of the sources and major analogues of all the Canterbury Tales prepared by members of the New Chaucer Society. This collection, the first to appear in over half a century, features such additions as a fresh interpretation of Chaucer's sources for the frame of the work, chapters on the sources of the General Prologue and Retractions, and modern English translations of all foreign language texts, with glosses for the Middle English. Chapters on the individual tales contain an updated survey of the present state of scholarship on their source materials. Several sources and analogues discovered during the past fifty years are found here together for the first time, and some other familiar sources are re-edited from manuscripts closer to Chaucer's copies. Besides the General Prologue and the Retractions, this volume includes chapters on the Miller, Summoner, Merchant, Physician, Shipman, Prioress, Sir Thopas, Canon's Yeoman, Manciple, the Knight and the prologues and tales of the Man of Law and Wife of Bath.Contributors: PETER BEIDLER, KENNETH A. BLEETH, LAUREL BROUGHTON, JOANNE CHARBONNEAU, WILLIAM E. COLEMAN, CAROLYN P. COLLETTE, VINCENT DI MARCO, PETER FIELD, TRAUGOTT LAWLER, ANITA OBERMEIER, ROBERT RAYMO, CHRISTINE RICHARDSON-HEY, JOHN SCATTERGOOD, NIGEL S. THOMPSON, EDWARD WHEATLEY, JOHN WITHRINGTON,
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