This book addresses the major problems of leadership in groups, organizations, and societies in the twenty-first century, when rapid change, complex dilemmas, and earth-shattering consequences affect the daily lives of people in the diverse contexts of social institutions, the corporate world, domestic politics, and international terrorism and conflict. The volume convenes a group of distinguished scholars, consultants, and leaders who address significant contemporary dilemmas that test the skills and knowledge of all concerned individuals. Benjamin Disraeli said, 'I am their leader; therefore I must follow them.' This book speaks directly to that intimate connection between leaders and followers.
Christians have often admired and venerated the martyrs who died for their faith, but for a long time thought that the bodies of martyrs should remain undisturbed in their graves. Initially, the Christian attitude towards the bones of the dead, saint or not, was that of respectful distance. The Beginnings of the Cult of Relics examines how this attitude changed in the mid-fourth century. Robert Wi'niewski investigates how Christians began to believe in the power of relics, first over demons, then over physical diseases and enemies. He considers how the faithful sought to reveal hidden knowledge at the tombs of saints and why they buried the dead close to them. An essential element of this new belief was a strong conviction that the power of relics was transferred in a physical way and so the following chapters study relics as material objects. Wi'niewski analyses how contact with relics operated and how close it was. Did people touch, kiss, or look at the very bones, or just at tombs and reliquaries which contained them? When did the custom of dividing relics begin? Finally, the book deals with discussions and polemics concerning relics, and attempts to find out the strength of the opposition which this new phenomenon had to face, both within and outside Christianity, on its way to become an essential element of medieval religiosity.
There can be no doubt that alkaline phosphatase is one of the most extensively in vestigated of all enzymes. This has resulted from the ubiquity of its distribution, and from the ease and sensitivity with which its activity can be measured. Unfortunately, these wide-ranging but often superficial experimental studies have been followed up by intensive and systematic investigations in only a few limited areas of the biochemistry and chemical pathology of alkaline phosphatase. The result has been the accumulation of a scientific literature of intimidating proportions, and the inevitable rediscovery of already known facts about the enzyme. Scientists are taught early in their careers that, in the words of Sir John Herschel, "Hasty generalization is the bane of science. " Nevertheless, moments arrive in all spheres of scientific activity when generalization becomes essential, to codify and to select from the mass of data already accumulated, and to provide starting points for new developments and new lines of investigation. This is especially true in a field such as alkaline phosphatase research, in which very real dangers exist that the seeds of fundamental understanding will be lost amidst an unexamined harvest of empirical observations. The history of the study of alkaline phosphatase provides several instances when valuable generalizations have emerged. Occasionally, the conclusions drawn on the basis of available evidence were wrong; more frequently, they have stood the test of further experimentation, and always, they have provided new insights into the nature and proper ties of this enzyme.
In this book, Robert L. Kelly challenges the preconceptions that hunter-gatherers were Paleolithic relics living in a raw state of nature, instead crafting a position that emphasizes their diversity, and downplays attempts to model the original foraging lifeway or to use foragers to depict human nature stripped to its core. Kelly reviews the anthropological literature for variation among living foragers in terms of diet, mobility, sharing, land tenure, technology, exchange, male-female relations, division of labor, marriage, descent and political organization. Using the paradigm of human behavioral ecology, he analyzes the diversity in these areas and seeks to explain rather than explain away variability, and argues for an approach to prehistory that uses archaeological data to test theory rather than one that uses ethnographic analogy to reconstruct the past.
Get the tools you need to evaluate, diagnose, and treat patients with neurogenic communication disorders! Introduction to Neurogenic Communication Disorders, 8th Edition provides a solid foundation in the neurology of communication, as well as the causes, symptoms, diagnosis, assessment, and management of commonly encountered neurogenic communication disorders in adults. A concise, evidence-based approach shows how to measure and treat abnormalities such as aphasia, dysarthria, right-hemisphere syndrome, and traumatic brain injury syndrome. This edition is updated with new coverage of laboratory tests, blast-related injuries to the head, and medications for dementia. Created by neurogenic communication disorders educator Robert H. Brookshire and continued by Malcolm R. McNeil, this bestselling text will enhance your skills in the rehabilitation of clients with neurogenic communication disorders. - A clear, concise approach makes complex material easy to follow and understand. - Clinical vignettes show how to apply principles to practice and illustrate how patients are evaluated and treated. - Thought questions at the end of each chapter are based on realistic scenarios and challenge you to assess your understanding, think critically, and apply information to clinical situations. Suggested answers are included in the appendix. - Clinically relevant sidebars include related facts, information, and tips for recall or therapy. - More than 200 photographs and images include anatomic illustrations, scans using various brain imaging techniques, and examples of assessment tests. - Evidence-based practice is reinforced by the use of scientific, evidence-based rationales to support the effectiveness of treatment approaches. - Student-friendly features enhance learning with chapter outlines, critical thinking exercises, medical protocols, sample paperwork, patient transcripts, commonly used medical abbreviations, and a glossary with definitions of key vocabulary. - General Concepts summary points highlight the most important material in each chapter. - NEW content on closed-head injuries as a consequence of blast injury is included in the Traumatic Brain Injury chapter, addressing a pathophysiology often found in Iraq and Afghanistan war veterans. - UPDATED content includes new information on medications for treatment of persons with dementia, the latest laboratory tests for neurologic assessment, and the most current cognitive rehabilitation approaches. - NEW! More Thought questions in each chapter help you apply concepts to clinical situations. - Additional content on evidence-based practice includes systematic reviews and meta-analyses relating to the efficacy and effectiveness of specific treatment approaches. - Additional graphics, clinical photographs, and tables depict key information and concepts.
Principles of Stem Cell Biology and Cancer: Future Applications and Therapeutics Tarik Regad, The John van Geest Cancer Research Centre, Nottingham Trent University, UK, Thomas J. Sayers, Centre for Cancer Research, National Cancer Institute, Frederick, USA and Robert Rees The John van Geest Cancer Research Centre, Nottingham Trent University, UK The field of cancer stem cells is expanding rapidly, with many groups focusing on isolating and identifying cancer stem cell populations. Although some progress has been made developing efficient cancer therapies, targeting cancer stem cells remains one of the important challenges facing the growing stem cell research community. Principles of Stem Cell Biology and Cancer brings together original contributions from international experts in the field to present the very latest information linking stem cell biology and cancer. Divided into two parts, the book begins with a detailed introduction to stem cell biology with a focus on the characterization of these cells, progress that has been made in their identification, as well as future therapeutic applications of stem cells. The second part focuses on cancer stem cells and their role in cancer development, progression and chemo-resistance. This section of the book includes an overview of recent progress concerning therapies targeting cancer stem cells. Features: An authoritative introduction to the link between stem cell biology and cancer. Includes contributions from leading international experts in the field. Well-illustrated with full colour figures throughout. This book will prove an invaluable resource for basic and applied researchers and clinicians working on the development of new cancer treatments and therapies, providing a timely publication of high quality reviews outlining the current progress and exciting future possibilities for stem cell research.
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