This book follows the genealogy of the Tasker and Blackburn families who originated in the area around Goole in Yorkshire. There were branches of the Tasker family in Rawcliffe, Airmyn, Hook, Cowick and Snaith. The Blackburn family farmed at Spaldington and Holme on Spalding Moor, near Howden in the East Riding, before moving to Goole Fields. Later, members of both families lived in Goole itself. The title of the book reflects these movements. But Taskers and Blackburns married into other families, and many of them moved away. There were sizeable branches in Hull, Todmorden and other parts of Yorkshire, and one large branch as far away as Seaham Harbour in County Durham. The book includes these side branches too. The family tree on the front cover provides an overview of the content. This book is available at a discount through the print-on-demand publisher www.lulu.com
Advances in cancer genomics are transforming our understanding of cancer, and have profound implications for its prevention, diagnosis, and treatment. Evolutionary dynamics suggests that as few as two mutations can cause transformation of normal cells into cancer stem cells. A process of Darwinian selection, involving a further three or more mutations, taking place over a period of years, can then result in progression to a life-threatening tumour. In many cases the immune response can recognise and eliminate the mutant cells, but most advanced tumours have mutations that activate immune checkpoints and enable the tumour to hide from the immune system. For the most hard-to-treat tumours, future progress will require molecular diagnostics to detect cancer-causing mutations in healthy subjects, and new drugs or vaccines that prevent the progression process. Chapters of this book deal with the signalling pathways that control cell division, and changes in these pathways in cancer cells. Three cell cycle checkpoints that are often mutated in cancer are analysed in detail. A discussion of chronic myeloid leukaemia illustrates the role of reactive oxygen species in driving progression from a chronic to an acute condition. A single drug that suppresses reactive oxygen can prevent disease progression and turn an otherwise deadly disease into a condition that can be managed to enable many years of normal life. Another chapter discusses chronic myelomonocytic leukaemia, a disease that involves both genetic and epigenetic change. Tumour progression is discussed as a multi-stage process in which cancer stem cells evolve into genetically unstable, invasive, metastatic, drug-resistant growths. Each of these stages can act as targets for drugs or immunomodulators, but the future of cancer treatment lies in understanding tumour dynamics, and arresting malignancy at the earliest possible stage. Evolutionary dynamics is a primarily mathematical technique, but the target readership will be tumour biologists, clinicians, and drug developers. Computational detail is provided in an online supplement, but the main text emphasises the implications of the dynamics for an understanding of tumour biology and does not require mathematical expertise.
Building upon the strengths of the first edition while continuing to extend the influence and reach of organizational behavior (OB), the Second Edition of this groundbreaking reference/ text analyzes OB from a business marketing perspective-offering a thorough treatment of central, soon-to-be central, contiguous, and emerging topics of OB to facilitate greater viability and demand of OB practice. New edition incorporates more comparative perspectives throughout! Contributing to the dynamic, interdisciplinary state of OB theory and practice, the Handbook of Organizational Behavior, Second Edition comprehensively covers strategic and critical issues of the OB field with descriptive analyses and full documentation details the essential principles defining core OB such as organizational design, structure, culture, leadership theory, and risk taking advances solutions to setting operational definitions throughout the field comparatively discusses numerous situations and variables to provide clarity to mixed or inconclusive research findings utilizes cross-cultural approaches to examine recent issues concerning race, ethnicity, and gender reevaluates value standards and paradigms of change in OB investigates cross-national examples of OB development, including case studies from the United States and India and much more! Written by 45 worldwide specialists and containing over 3500 references, tables, drawings, and equations, the Handbook of Organizational Behavior, Second Edition is a definitive reference for public administrators, consultants, organizational behavior specialists, behavioral psychologists, political scientists, and sociologists, as well as a necessary and worthwhile text for upper-level undergraduate and graduate students taking organizational behavior courses in the departments of public administration, psychology, management, education, and sociology.
Building upon the strengths of the first edition while continuing to extend the influence and reach of organizational behavior (OB), the Second Edition of this groundbreaking reference/ text analyzes OB from a business marketing perspective-offering a thorough treatment of central, soon-to-be central, contiguous, and emerging topics of OB to facilitate greater viability and demand of OB practice. New edition incorporates more comparative perspectives throughout! Contributing to the dynamic, interdisciplinary state of OB theory and practice, the Handbook of Organizational Behavior, Second Edition comprehensively covers strategic and critical issues of the OB field with descriptive analyses and full documentation details the essential principles defining core OB such as organizational design, structure, culture, leadership theory, and risk taking advances solutions to setting operational definitions throughout the field comparatively discusses numerous situations and variables to provide clarity to mixed or inconclusive research findings utilizes cross-cultural approaches to examine recent issues concerning race, ethnicity, and gender reevaluates value standards and paradigms of change in OB investigates cross-national examples of OB development, including case studies from the United States and India and much more! Written by 45 worldwide specialists and containing over 3500 references, tables, drawings, and equations, the Handbook of Organizational Behavior, Second Edition is a definitive reference for public administrators, consultants, organizational behavior specialists, behavioral psychologists, political scientists, and sociologists, as well as a necessary and worthwhile text for upper-level undergraduate and graduate students taking organizational behavior courses in the departments of public administration, psychology, management, education, and sociology.
Society for Educational Studies Annual Book Prize winner: 2nd Prize This ground-breaking volume draws upon a rich and variegated range of methodologies to understand more fully the practices, policies and resources available in and to religious education in British schools. The descriptions, explanations and analyses undertaken here draw on an innovative combination of policy work, ethnography, Delphi methods, Actor Network Theory, questionnaires, textual analysis as well as theological and philosophical insight. It traces the evolution of religious education in a post-religious age from the creation of policy to the everyday experiences of teachers and students in the classroom. It begins by analysing the way in which policy has evolved since the 1970s with an examination of the social forces that have shaped curriculum development. It goes on to explore the impact and intentions of a diverse group of stakeholders with sometimes competing accounts of the purposes of religious educations. It then examines the manner in which policy is, or is not, enacted in the classroom. Finally, it explores contradictions and confusions, successes and failures, and the ways in which wider public debates enter the classroom. The book also exposes the challenge religious education teachers have in using the language of religion.
From the deadly shores of North Africa to the invasion of Sicily to the fierce jungle hell of the Pacific, the contribution of the World War II Ranger Battalions far outweighed their numbers. They were ordinary men on an extraordinary mission, experiencing the full measure of the fear, exhaustion, and heroism of combat in nearly every major invasion of the war. Whether spearheading a landing force or scouting deep behind enemy lines, these highly motivated, highly trained volunteers led the way for other soldiers -- they were Rangers. With first-person interviews, in-depth research, and a complete appendix naming every Ranger known to have served, author Robert Black, a Ranger himself, has made the battles of WWII come to life through the struggles of the men who fought to win the greatest war the world has ever seen.
The most comprehensive reference on voice care and science ever published! Substantially revised and updated since the previous edition published in 2005, Professional Voice: The Science and Art of Clinical Care, Fourth Edition provides the latest advances in the field of voice care and science. In three volumes, it covers basic science, clinical assessment, nonsurgical treatments, and surgical management. Twenty new chapters have been added. These include an in-depth chapter on pediatric voice disorders, chapters detailing how hormonal contraception, autoimmune disorders, and thyroid disorders affect the voice, as well as chapters on the evolution of technology in the voice care field, and advances in imaging of the voice production system. The appendices also have been updated. They include a summary of the phonetic alphabet in five languages, clinical history and examination forms, a special history form translated into 15 languages, sample reports from a clinical voice evaluation, voice therapy exercise lists, and others. The multidisciplinary glossary remains an invaluable resource. Key Features With contributions from a Who's Who of voice across multiple disciplines120 chapters covering all aspects of voice science and clinical careFeatures case examples plus practical appendices including multi-lingual forms and sample reports and exercise listsComprehensive indexMultidisciplinary glossary What's New Available in print or electronic format20 new chaptersExtensively revised and reorganized chaptersMany more color photographs, illustrations, and case examplesFully updated comprehensive glossaryMajor revisions with extensive new information and illustrations, especially on voice surgery, reflux, and structural abnormalities New Chapters 1. Formation of the Larynx: From Hox Genes to Critical Periods 2. High-Speed Digital Imaging 3. Evolution of Technology 4. Magnetic Resonance Imaging of the Voice Production System 5. Pediatric Voice Disorders 6. The Vocal Effects of Thyroid Disorders and Their Treatment 7. The Effects of Hormonal Contraception on the Voice 8. Cough and the Unified Airway 9. Autoimmune Disorders 10. Respiratory Behaviors and Vocal Tract Issues in Wind Instrumentalists 11. Amateur and Professional Child Singers: Pedagogy and Related Issues 12. Safety of Laryngology Procedures Commonly Performed in the Office 13. The Professional Voice Practice 14. Medical-Legal Implications of Professional Voice Care 15. The Physician as Expert Witness 16. Laryngeal Neurophysiology 17. The Academic Practice of Medicine 18. Teamwork 19. Medical Evaluation Prior to Voice Lessons 20. Why Study Music? Intended Audiences Individuals While written primarily for physicians and surgeons, this comprehensive work is also designed to be used by (and written in language accessible to) speech-language pathologists, singing voice specialists, acting voice specialists, voice teachers, voice/singing performers, nurses, nurse practitioners, physician assistants, and others involved in the care and maintenance of the human voice. Libraries It is a must-have reference for medical and academic libraries at institutions with otolaryngology, speech-language pathology, music, nursing and other programs related to the human voice.
Kathleen Erickson, M.D. works part time in THE CLINIC caring for young women whose needs range from counseling, to birth control, and to therapeutic abortion. Kathleen, a 38 year old widow with two children, is a very active pro-choice obstetrician and gynecologist. As such she receives many threats to her life, including a gunshot wound in the middle of the night. She is sued for malpractice after performing a legal therapeutic abortion. A charge of manslaughter is added when the plaintiffs attorney discovers that all signed permits for the surgery have disappeared. The major frustration in her life is that of exposing a traitor, a Judas in THE CLINIC, whose hidden aim is to eliminate all abortion clinics by law or bombing. The final pages disclose this Judas as a most unlikely individual.
Around Dansville illustrates the history of an important and proud community. Clara Barton lived in Dansville for a decade, and the first American Red Cross chapter was founded here in 1881. The town's famous spa drew many notable Americans, and the first dry cereal and a center for healthy living were developed here. A wide range of products, including shoes of all sizes and giant boilers, were made here and shipped across the country. Around Dansville is a tribute to this rich and colorful past. Around Dansville illustrates the history of an important and proud community. Clara Barton lived in Dansville for a decade, and the first American Red Cross chapter was founded here in 1881. The town's famous spa drew many notable Americans, and the first dry cereal and a center for healthy living were developed here. A wide range of products, including shoes of all sizes and giant boilers, were made here and shipped across the country. Around Dansville is a tribute to this rich and colorful past.
The bestselling treatment planning system for mental health professionals The Addiction Treatment Planner, Fifth Edition provides all the elements necessary to quickly and easily develop formal treatment plans that satisfy the demands of HMOs, managed care companies, third-party payors, and state and federal agencies. New edition features empirically supported, evidence-based treatment interventions Organized around 43 behaviorally based presenting problems, including substance use, eating disorders, schizoid traits, and others Over 1,000 prewritten treatment goals, objectives, and interventions—plus space to record your own treatment plan options Easy-to-use reference format helps locate treatment plan components by behavioral problem Includes a sample treatment plan that conforms to the requirements of most third-party payors and accrediting agencies including CARF, The Joint Commission (TJC), COA, and the NCQA
Trivia Why's will make you trivia wise with these great features: 1) Over 2,000 questions with multiple-choice answers are each accompanied by a related factoid. Why is this answer correct (and not that one)? Why else is this person famous (or infamous)? Why was this event historically significant? 2) By cycling through six standard genus categories, this book makes an excellent supplement to your favorite trivia board game while providing a healthy variety of topics for your reading pleasure. Answers are hidden from view while the questions are being read and appear in the same block on the same side of the book two pages later. 3) Every question and answer has been carefully researched for accuracy and recently updated to include the latest available data. Since trivia is a moving target, however, updates and corrections will be posted to the triviawhys.com web site.
Western Water A to Z is the first ever field guide to Western water. Reinventing this twentieth-century genre for a twenty-first-century audience, Robert R. Crifasi answers questions about rivers, water projects, the culture of water, the ecosystems water projects have created or destroyed, and the reliance of cities, farms, and industries on this critical resource. Organized as a collection of terms, the book addresses the most salient water issues and provides helpful background information regarding their origins and implications. Photographs serve a vital role in the cultural dialogue on water and stand as an equal partner to the text. Each subject is covered in about one page and is accompanied by one or two striking images from famous photographers like Margaret Bourke-White, Carleton E. Watkins, Arthur Rothstein, William Henry Jackson, and Dorothea Lang as well as Crifasi’s own work. Water often finds itself at the center of our cultural discourse in art, cinema, and literature, which play essential roles in shaping our understanding and experience of Western water. Crifasi also engages personalities that are nearly synonymous with Western water—John Wesley Powell, Elwood Mead, and Floyd Dominy, among others—to show how their lives intertwined with and often influenced the course of water development across the region. Travelers, adventurers, students, and anyone interested in water will find Western Water A to Z a handy and entertaining reference guide.
Long recognized as the leading text in this dynamic field, Rogers’ Textbook of Pediatric Intensive Care provides comprehensive, clear explanations of both the principles underlying pediatric critical care disease and trauma as well as how these principles are applied. Led by Drs. Donald H. Shaffner, John J. McCloskey, Elizabeth A. Hunt, and Robert C. Tasker, along with a team of 27 section editors as well as more than 250 expert global contributors, the fully revised Sixth Edition brings you completely up to date on today’s understanding, treatments, technologies, and outcomes regarding critical illness in children.
This work provides in-depth analysis of the origins of landscape ecology and its close alignment with the understanding of scale, the causes of landscape pattern, and the interactions of spatial pattern with a variety of ecological processes. The text covers the quantitative approaches that are applied widely in landscape studies, with emphasis on their appropriate use and interpretation. The field of landscape ecology has grown rapidly during this period, its concepts and methods have matured, and the published literature has increased exponentially. Landscape research has enhanced understanding of the causes and consequences of spatial heterogeneity and how these vary with scale, and they have influenced the management of natural and human-dominated landscapes. Landscape ecology is now considered mainstream, and the approaches are widely used in many branches of ecology and are applied not only in terrestrial settings but also in aquatic and marine systems. In response to these rapid developments, an updated edition of Landscape Ecology in Theory and Practice provides a synthetic overview of landscape ecology, including its development, the methods and techniques that are employed, the major questions addressed, and the insights that have been gained.”
Obtain all the core knowledge in pain management you need from one of the most trusted resources in the field. The new edition of Practical Management of Pain gives you completely updated, multidisciplinary overview of every aspect of pain medicine, including evaluation, diagnosis of pain syndromes, rationales for management, treatment modalities, and much more. In print and online, it is all the expert guidance necessary to offer your patients the best possible relief. "In summary, this is the best explanation of what lies behind MRI that I have read, taking what can be a dry subject and making it readily understandable and really interesting. I would recommend it to anyone starting their MRI training and anyone trying to teach MRI to others." Reviewed by RAD Magazine, June 2015 Understand and apply the latest developments in pain medicine with brand-new chapters covering disability assessment, central post-stroke pain, chronic widespread pain, and burn pain. Effectively ease your patients' pain with today's best management techniques, including joint injections, ultrasound-guided therapies, and new pharmacologic agents (such as topical analgesics). Access up-to-the-minute knowledge on all aspects of pain management, from general principles to specific management techniques, with contributions from renowned experts in the field. Read the full text and view all the images online at expertconsult.com. Understand and apply the latest developments in pain management with brand-new chapters covering disability assessment, central post-stroke pain, widespread chronic pain, and burn pain. Effectively ease your patients' pain with today's best management techniques, including joint injections, ultrasound-guided therapies, and new pharmacologic agents (such as topical analgesics).
Written by one of the most prolific and respected researchers in food safety, this volume describes molecular techniques for the detection and discrimination of major infectious bacteria associated with foods. Each chapter deals with a specific organism and techniques applied to that organism. Particular focus is placed on genes associated with pathogenicity used in the polymerase chain reaction (PCR) including real-time PCR for specific detection of pathogenic bacteria and the inherent limitations of such methodology with certain pathogens. Methods for extracting microorganisms from complex food matrices andDNA purification techniques are also emphasized.
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