During an expedition in Antarctica geologist Ben Brooks discovers by sheer coincidence a very strange small object. It's harder than diamond, and since it's lighter than air it floats around his lab. When searching government support for further research on this bizarre object it is confiscated, and a number of events start to happen. A famous NASA scientist disappears (murdered?) and Brooks and his assistant Sally have to go undercover with the object, hunted by a secret organization under the command of a grim US Army general. Brooks and Sally flee, but will they succeed to escape arrest by the FBI, the CIA, the US Army, the US Navy and the US Air Force when all of these armed forces join hands in the manhunt? And why poses such a small harmless object such a threat to the national security of the USA? Why does the US government commit third degree murder, burglary and larceny to take it away from them?
Ann Farrell notices two strange mourners at her father's funeral. At the reading of her father's legal will it appears they have played a key role in her father's mysterious past. Her determined pursuit to unveil this mystery leads her to France, where her father allegedly was a British secret agent during World War II. There she discovers the shocking truth.The story of four different eras in the life of two young men - courageous soldiers, close friends and successful barristers - their ambiguous hate/love relation gradually turning them into rancorous adversaries, the consequent aftermath of their horrible war experience that atrophied part of their soul.As the story grows, so does suspense. Why did the British Prime Minister, Winston Churchill, sacrifice two brave young men without mercy? And who is Farrell's daughter?In combat many young men lose their life or limbs, they are called war heroes. But some lose their emotional balance on the battlefield. They are called cowards
Protestant evangelical Christian schools are the fastest-growing segment of American private school education. Despite their notable individual autonomy, these schools have retained a consistent belief system and mission over several decades. Private religious schools can be traced to our nation’s earliest origins. Why is it that these unique educational institutions arose in twentieth-century America and have continued to thrive? A Christian America Restored seeks to delve into the beginnings of private Christian schools and discovers that while they are relatively new on the educational landscape of America, their roots are actually quite deep, connecting with the ongoing dreams of our nation’s conservative evangelicals.
With the 13th edition, Wintrobe’s Clinical Hematology once again bridges the gap between the clinical practice of hematology and the basic foundations of science. Broken down into eight parts, this book provides readers with a comprehensive overview of: Laboratory Hematology, The Normal Hematologic System, Transfusion Medicine, Disorders of Red Cells, Hemostasis and Coagulation; Benign Disorders of Leukocytes, The Spleen and/or Immunoglobulins; Hematologic Malignancies, and Transplantation. Within these sections, there is a heavy focus on the morphological exam of the peripheral blood smear, bone marrow, lymph nodes, and other tissues. With the knowledge about gene therapy and immunotherapy expanding, new, up-to-date information about the process and application of these therapies is included. Likewise, the editors have completely revised material on stem cell transplantation in regards to both malignant and benign disorders, graft versus host disease, and the importance of long-term follow-up of transplantation survivors.
Jesse James Hollywood grew up in L.A.'s upscale West Hills with every imaginable privilege. By the age of 19, he owned a spacious house, a tricked-out car, a closet full of designer clothes. His lifestyle of drinking, partying and getting high was bankrolled by his chosen career: drug dealing. In 2000, Ben Markowitz, another teen from a 'good family', found himself with a dope tab he couldn't pay. A standoff between dealer and druggie exploded when Hollywood, along with William Skidmore and Jesse Rugge, both 20, spotted Ben's brother, Nick, 15, walking near his parents' home. Witnesses saw the three men attack Nick, then shove him into a van and drive off. But assault and kidnapping were only the beginning... On the last night of Nick's life, he was taken to an isolated area outside Santa Barbara known as the Lizard's Mouth. There, he was shot to death and buried in a shallow grave. But the story was far from over. Because mastermind Jesse James, like his namesake, knew how to run and hide. With his handsome face at the top of the FBI's Most Wanted list, he lived in luxury until the long arm of the law reached out to pull him back home for justice...
This book focuses on an important aspect of the methods in laboratory animal inhalation toxicology. It is targeted to students in toxicology programs and scientists contemplating performing inhalation studies.
Lewin’s Gastrointestinal Pathology and Its Clinical Implications, Second Edition This comprehensive, two-volume resource highlights the practical aspects the pathology of biopsies and gross specimens, the clinical/pathological correlation, and differential diagnoses, and the ways in which these affect the management of patients with gastrointestinal disorders. The authors provide valuable insights on many important areas of gastrointestinal pathology, and openly address controversies within the specialty. This all-inclusive work stands alone in its illustrative quality and in its emphasis on the clinical implications of patient management as related to pathologic findings. The Second Edition has been completely revised to reflect two decades of advances in the field. The book’s focus on clinical/pathological correlations and differential diagnoses emphasizes their affect on patient management. Major revisions of the chapters on colitis and gastritis feature new approaches to treatment. Over 2100 full-color illustrations highlight pathologic features to sharpen diagnostic skills and guide treatment choices. NEW to the Second Edition... Completely revised content reflects two decades of advances in the field. Focus on clinical/pathological correlations and differential diagnoses emphasizes their affect on patient management Major revisions of the chapters on colitis and gastritis feature new approaches to treatment. Over 2100 full-color illustrations highlight pathologic features to sharpen diagnostic skills and guide treatment choices.
Unparalleled in scope and content, Surgical Pathology of the GI Tract, Liver, Biliary Tract and Pancreas provides the most relevant and up-to-date clinical, etiologic, molecular, and therapeutic management information for surgical pathologists in training and in practice. The fully revised 4th Edition of this award-winning title offers a wealth of information in this fast-changing field, including recent advances in molecular biology and immunohistochemistry, in a clearly written, well-structured manner that is easy to read and navigate. This one-stop reference for the entire gastrointestinal system enables you to improve turnaround time when diagnosing a specimen and to clearly report on the prognosis and therapeutic management options to surgical and medical colleagues. Covers the latest developments in molecular technologies and immunohistochemical markers to provide useful diagnostic and prognostic information and inform therapeutic decisions. Provides all the necessary tools to make a comprehensive diagnostic workup, including data from ancillary techniques and molecular findings whenever appropriate. Incorporates more than 3000 high-quality color illustrations to help you recognize and diagnose any tissue sample under the microscope. Reviews next-generation sequencing (NGS) to help identify targetable mutations in gastrointestinal tract tumors and provide more accurate classification and precision therapies. Features extensive tables, graphs, and flowcharts to help you effectively grasp complex topics and streamline your decision-making. Helps you avoid diagnostic errors with practical advice on pitfalls in differential diagnosis. Incorporates the latest WHO guidelines throughout. Winner of the 2015 BMA Medical Book Awards First Prize Award in Pathology.
In response to concerns that the educational system - from public schools through colleges, universities, and apprenticeship programs - cannot adequately prepare students for work in the new economy, Integrating School and Workplace Learning in Canada proposes alternation - a hybrid form of learning that, by combining experiential and cognitive learning skills, allows individuals to develop the relevant skills and intellectual capabilities to address and solve complex problems encountered in the workplace. Alternation involves not only a curricular balance between the theoretical and the practical but also two distinct venues for learning - the classroom and the workplace. The authors discuss cognitive and social learning, its implementation in a variety of settings, its role in smoothing the school/work transition process, and its potential to contribute to the knowledge and skills needed by the workforce. They bring a wide range of disciplinary perspectives to bear in their analyses of the principles and practices of alternation, providing historical, theoretical, and practical insights. Their analysis contributes to and extends the current debate and discussion surrounding necessary changes in our education and training practices.
The updated edition of Surgical Pathology of the GI Tract, Liver, Biliary Tract and Pancreas is designed to act as a one-stop medical reference book for the entire gastrointestinal system, providing exhaustive coverage and equipping you with all of the necessary tools to make a comprehensive diagnostic workup. You'll access thousands of high-quality illustrations and eight brand-new chapters, so you can recognize and diagnose any pathological slide you encounter. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Make a comprehensive diagnostic workup with data from ancillary techniques and molecular findings whenever appropriate. Effectively grasp complex topics and streamline decision-making by using extensive tables, graphs, and flowcharts. Avoid diagnostic errors thanks to practical advice on pitfalls in differential diagnosis. Navigate the book quickly with a "road map" featured at the beginning of each chapter. Provide the clinician with the most accurate and up-to-date diagnostic and prognostic indicators, including key molecular aspects of tumor pathology, with access to the latest classification and staging systems available. Evaluate diagnostically challenging cases using diagnostic algorithms. Stay abreast of the latest advances with eight new chapters: Autoimmune Disorders of the GI Tract; Drug Induced Disorders of the GI Tract; Molecular Diagnostics of Tubal Gut Neoplasms; Molecular Diagnostics of the Gallbladder, Extrahepatic Biliary Tree, and Pancreatic Tumors; Tumors of the Ampulla; Molecular Diagnostics of Hepatocellular Neoplasms; Approach to the Liver Biopsy, and Approach to Gastrointestinal Tract Biopsies. Remain at the forefront of your field with coverage of new molecular and genetic markers in GI neoplasms; updated knowledge on liver and biliary tree pathology; and expanded information on tumors of the ampulla. Recognize and diagnose any tissue sample under the microscope with help from over 3000 high-quality color illustrations.
Kiss & Sell: Writing for Advertising discusses different subjects and media, from print and broadcast to interactive media, as well as tactics and strategies employed by copywriters. Commentary, example and advice from leading players in the advertising world offer the aspiring professional important insight and meaningful guidance. Detailed explanations outline the aims of various work and how it was achieved. As a copywriter, your job is not to amuse or entertain, but rather to sell products. By examining the campaigns here, youll see why writing copy is as much a craft as it is an art, and, along the way, you'll learn how to succeed in this glamorous but cutthroat industry.
3 nant expression systems have been used to make MHC molecules con taining a single peptide of interest. To date, fifteen single peptide class I structures (incorporating three different HLA and two different H-2 allotypes/isotypes) and four additional class II structures (two single peptide complexes and two superantigen complexes) have been reported. These advances have enabled us to study the atomic detail of antigen presentation and the general mechanisms behind peptide binding, and begin to construct models of T cell recognition. Another area of research which has exploded over the past five years has been the identification of MHC-associated peptides. There are several methods one can use to determine the sequence identity of MHC restricted peptides. Historically, the most successful technique, albeit crude and encumbered with serious limitations, has been the use of overlapping synthetic peptides and T cell clones. Unfortunately, this method absolutely requires: (i) knowledge of the target antigen; (ii) availability of T cell clones; and (iii) a relatively short overall length for the target source protein, such that a set of overlapping pep tides can be affordably synthesized. Briefly, the entire sequence of the tar get protein is chemically synthesized using overlapping peptides which are then screened for biological activity using standard T cell presen tation assays. Despite its limitations, this method was used to identify the first immunodominant epitopes reported in the literature and con tinues to be used successfully today.
A comprehensive reference standard for the discipline, Canine and Feline Gastroenterology covers the biology, pathobiology, and diagnosis and treatment of diseases of the gastrointestinal, pancreatic, and hepatobiliary systems. An international team of experts, including 85 authors from 17 different countries, led by Robert Washabau and Michael Day, covers everything from minor problems such as adverse food reactions to debilitating inflammatory, infectious, metabolic, and neoplastic diseases of the digestive system. This authoritative text utilizes an evidence-based approach to reflect the latest science and research, complemented by principles of problem solving, algorithms to improve clinical diagnoses, and extensive full-color illustrations. For generalists and specialists alike, this gastroenterology reference should be part of every serious practitioner's professional library. - A comprehensive, 928-page reference standard covers the discipline of canine and feline gastroenterology. - An international focus is provided by 85 authors from 17 different countries, including renowned experts in veterinary gastroenterology, internal medicine, pathology, clinical pathology, radiology, and infectious disease. - Coverage of the entire breadth and depth of gastroenterology ranges from biology to pathobiology, as well as diagnosis and treatment of diseases of the gastrointestinal, pancreatic, and hepatobiliary systems. - Current information on GI microflora, immunology, cellular growth, and systems integration provides a foundation for treating clinical problems. - Coverage of diseases in dogs and cats includes the oral cavity, esophagus, stomach, small intestine, large intestine, colon, anorectum, liver and biliary tract, exocrine pancreas, peritoneum, and associated vasculature. - A focus on patient management examines the full range of procedures and techniques essential to diagnosis and treatment from clinical signs and diagnosis to nutritional support and pharmacologic management of disease. - Clear explanations of current diagnostic modalities include laboratory tests, molecular methods, diagnostic imaging, endoscopy, and histopathology, also showing how to interpret and utilize results. - A strong clinical approach emphasizes need-to-know information for managing the common and not-so-common G.I. clinical problems of everyday practice. - Full-color photographs and illustrations depict concepts, conditions, and procedures. - An evidence-based medicine perspective reflects the latest research as well as the modern practice of veterinary medicine. - Logical, coherent, and consistent internal organization makes this a reader-friendly edition. - Problem-based algorithms help in diagnosing every G.I. clinical problem from A to Z. - A stand-alone section on the pharmacologic approach to G.I. disease offers quick and easy drug reference.
Now with full-color illustrations throughout, dozens of new review questions, and state-of-the-art coverage of this fast-changing area, Pediatric Gastrointestinal and Liver Disease, 6th Edition, remains the leading text in the field. You'll find definitive guidance on diagnosis and treatment from experienced editors Drs. Robert Wyllie, Jeffrey S. Hyams, and Marsha Kay, as well as globally renowned contributors who share their knowledge and expertise on complex issues. - Features an enhanced art program with full-color anatomical figures, clinical photos, and other illustrations throughout the text. - Includes a new chapter on fecal transplantation (FCT), covering donor and recipient screening, preparation, delivery, follow-up, and safety considerations, as well as investigative uses for FCT for disorders such as IBD, IBS, and D-lactic acidosis. - Prepares you for certification and recertification with more than 400 board review-style questions, answers, and rationales – 30% new to this edition. - Includes detailed diagrams that accurately illustrate complex concepts and provide at-a-glance recognition of disease processes. - Contains numerous algorithms that provide quick and easy retrieval of diagnostic, screening, and treatment information. - Provides up-to-date information on indigenous flora and the gut microbiome and clinical correlations to treatment, as well as advancements in liver transplantation including split liver transplantation (SLT) and living donor liver transplantation (LDLT). - Details key procedures such as esophagogastroduodenoscopy and related techniques; colonoscopy and polypectomy; endoscopic retrograde cholangiopancreatography; capsule endoscopy and small bowel enteroscopy; gastrointestinal pathology; and more.
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