In 1543, Nicolaus Copernicus publicly defended his hypothesis that the earth is a planet and the sun a body resting near the center of a finite universe. But why did Copernicus make this bold proposal? And why did it matter? The Copernican Question reframes this pivotal moment in the history of science, centering the story on a conflict over the credibility of astrology that erupted in Italy just as Copernicus arrived in 1496. Copernicus engendered enormous resistance when he sought to protect astrology by reconstituting its astronomical foundations. Robert S. Westman shows that efforts to answer the astrological skeptics became a crucial unifying theme of the early modern scientific movement. His interpretation of this long sixteenth century, from the 1490s to the 1610s, offers a new framework for understanding the great transformations in natural philosophy in the century that followed.
The Third Edition (formerly titled International Public Health) brings together contributions from the world's leading authorities into a single comprehensive text. It thoroughly examines the wide range of global health challenges facing low and middle income countries today and the various approaches nations adopt to deal with them. These challenges include measurement of health status, infectious and chronic diseases, injuries, nutrition, reproductive health, global environmental health and complex emergencies. This thorough revision also explores emerging health systems, their financing, and management, and the roles of nation states, international agencies, the private sector and nongovernmental organizations in promoting health. Your students will come away with a clear understanding of how globalization is impacting on global health, and of the relationship between health and economic development.
With more than 1100 computer-generated figures, line drawings, and photographs, Atlas of Immunology clearly demonstrates thata picture is worth a thousand words. Written for students, basic scientists, and clinicians, this second edition provides a thorough and up-to-date treatment of all the concepts needed to comprehend contemporary imm
Now with full-color illustrations throughout, dozens of new review questions, and state-of-the-art coverage of this fast-changing area, Pediatric Gastrointestinal and Liver Disease, 6th Edition, remains the leading text in the field. You'll find definitive guidance on diagnosis and treatment from experienced editors Drs. Robert Wyllie, Jeffrey S. Hyams, and Marsha Kay, as well as globally renowned contributors who share their knowledge and expertise on complex issues. - Features an enhanced art program with full-color anatomical figures, clinical photos, and other illustrations throughout the text. - Includes a new chapter on fecal transplantation (FCT), covering donor and recipient screening, preparation, delivery, follow-up, and safety considerations, as well as investigative uses for FCT for disorders such as IBD, IBS, and D-lactic acidosis. - Prepares you for certification and recertification with more than 400 board review-style questions, answers, and rationales – 30% new to this edition. - Includes detailed diagrams that accurately illustrate complex concepts and provide at-a-glance recognition of disease processes. - Contains numerous algorithms that provide quick and easy retrieval of diagnostic, screening, and treatment information. - Provides up-to-date information on indigenous flora and the gut microbiome and clinical correlations to treatment, as well as advancements in liver transplantation including split liver transplantation (SLT) and living donor liver transplantation (LDLT). - Details key procedures such as esophagogastroduodenoscopy and related techniques; colonoscopy and polypectomy; endoscopic retrograde cholangiopancreatography; capsule endoscopy and small bowel enteroscopy; gastrointestinal pathology; and more.
By 1940, immunological mechanisms had been proved to have fundamental influ ences on a great number and variety of skin reactions, and skin diseases had brought to light a great number of fundamental immunological mechanisms that were basic to a wide range of different diseases, dermatological and nondermato logical. The preeminence of dermatological research in the advancement of immu nological knowledge should not astonish anyone. For the skin is not only the most easily accessible tissue for producing and studying immunological reactions, it is also the great organ of protection that meets the first onslaughts of inimical environmental forces and agents-potential enemies, both living and dead. And protection is in essence what immunology is all about. To get an idea of the long-established role that testing the skin and the study of its many reactions has played in advancing general immunology, one need recall only smallpox vaccination; tuberculin testing; testing with fungal extracts; skin testing in hay fever, asthma, and serum sickness; skin tests with toxins and toxoids; the patch test; the passive transfer of skin-adhering antibodies (reagins); skin sensitization by simple chemicals; and similar dermatological procedures that have exerted their influence on medical and scientific disciplines far beyond dermatology.
Stress and Immunity introduces and updates the status of research on stress and immunity. Clinical aspects of stress and immunity are presented in the first 17 chapters and include discussions regarding the influence of depression disorders on immune functions and stress interrelationships with cancer, AIDS, Chronic Fatigue Syndrome, and Herpes Simplex infections. There is also a review of physical exercise and immunity. The second half of the book is devoted to discussions regarding basic research being conducted in the field of stress and immunity. This includes discussions on the interrelationships of the central nervous system and the immune system and research on stress hormones (e.g., enkephalins, endorphins) as they interrelate with the immune system. In addition, animal models for the study of stress and immunity are discussed. Psychiatrists, neurologists, psychologists, clinical psychologists, internists, immunologists, and researchers in psychosomatic disorders should consider this an essential reference volume.
Sicily is the largest island in the Mediterranean Sea, one of the most varied in appearance, and least insular in terms of cultural development. It has often been described as a meeting place of cultures, where East meets West.
Pseudomonas aeruginosa the Opportunist provides an in depth analysis of clinically relevant pathogenetic mechanisms and selected disease states. The book presents the most current discussion of pathogenic mechanisms logically arranged from the microbiology of the Pseudomonadaceae and initial mucosal adherence, progessing to microcolony formation and release of a wide assortment of virulence factors, and closing with the contribution of host cells to the disease process. Cellular and molecular disease mechanisms are covered, including genetic regulation of virulence-associated bacterial products. Future research trends are highlighted as well. Pseudomonas aeruginosa the Opportunist is an excellent reference for bacteriologists, clinical investigators, and practicing clinicians representing a variety of specialties, including ophthalmology, pediatrics, and transplantation.
The Atlas of Immunology is a unique pictorial reference, containing more than 1000 illustrations depicting essentially every important concept in understanding immunology. Diagrams are included for all levels of understanding; some show basic ideas, while others provide a more detailed treatment for specialists.
Based on the study of over 500 surviving manuscript school books, this comprehensive 2001 study of the curriculum of school education in medieval and Renaissance Italy contains some surprising conclusions. Robert Black's analysis finds that continuity and conservatism, not innovation, characterize medieval and Renaissance teaching. The study of classical texts in medieval Italian schools reached its height in the twelfth century; this was followed by a collapse in the thirteenth century, an effect on school teaching of the growth of university education. This collapse was only gradually reversed in the two centuries that followed: it was not until the later 1400s that humanists began to have a significant impact on education. Scholars of European history, of Renaissance studies, and of the history of education will find that this deeply researched and broad-ranging book challenges much inherited wisdom about education, humanism and the history of ideas.
Providing a substantive approach to the issue, Management of Library and Archival Security: From the Outside Looking In gives librarians and collection directors practical and helpful suggestions for developing policies and procedures to minimize theft. In addition, this text prepares you to deal with the aftermath of a robbery or natural disaster that destroys priceless materials. Through expert opinions and advice, Management of Library and Archival Security will teach you how to protect and secure invaluable collections and the finances invested in them. In addition, Management of Library and Archival Security offers numerous suggestions for preserving collections from environmental hazards and natural disasters. Contributors discuss several possible scenarios leading to the loss or destruction of library or archive materials and offer numerous measures of protection, including: implementing timely inventory standards, using approved marketing practices, keeping good user records, and having knowledge of insurance coverage making a recovery plan that deals with the impact of a theft and how it may affect staff and the actual workings of a department or archive knowing who to contact after a theft, such as local enforcement agencies, federal officials, and listing the theft on the Library Security Officer Listserv (LSO) to alert local and national libraries and collectors to the crime incorporating internal audits in a university setting to prevent crime and ensure accounting and administration controls are effective and efficient instituting a preservation program for collections, which includes temperature control of the indoor environment, studying the building design for weaknesses or potential dangers, reformatting deteriorating materials, and limiting the handling of materials making plans for the aftermath of a disaster, such as creating methods for risk assessment, developing collection priorities, and making rehabilitation policies for materials The chapters in Management of Library and Archival Security offer unique insight from a former F.B.I. agent with extensive experience in library thefts, a preservation specialist, and an archivist with extensive conservation experience in order to provide you with all of the information you need to safeguard library and archive collections against theft, environmental conditions, natural disasters, and resultant financial loss.
From the beginning, immunologists have maintained a unique nomenclature that has often mystified and even baffled their colleagues in other fields, causing them to liken immunology to a black box. With more than 1200 illustrations, the Illustrated Dictionary of Immunology, Third Edition provides immunologists and nonimmunologists a single-volume resource for the many terms encountered in contemporary immunological literature. Encyclopedic in scope and including more than 1200 illustrations, the content ranges from photographs of historical figures to molecular structures of recently characterized cytokines, the major histocompatibility complex molecules, immunoglobulins, and molecules of related interest to immunologists. These descriptive illustrations provide a concise and thorough understanding of the subject. To reflect modern advances, the third edition includes entries on immunopharmacology, newly described interleukins, comparative immunology, immunity to infectious diseases, and expanded definitions in all of the immunological subspecialities. Providing unprecedented breadth and detail, this readily accessible book is not only a pictorial reference but also a primary resource.
Careers in Psychology, Sixth Edition helps students navigate and plan for their futures by offering exposure to the rich careers in each subfield of psychology and prompting students to consider the what, why and how of each option. With salary insights, career guidance, and job search tips post-graduation, the authors equip students to make informed choices about their future careers.
At the beginning of the new millennium, it is opportune to raveling of the molecular pathways of impaired host - review what has been accomplished in the field of infec- fense mechanisms and the characterization of the genetic tious diseases during the last decades of the previous mutations involved, with the prospect of novel strategies century. The paradigm of the immunocompromised host for therapeutic interventions and possible corrective gene has taught much about the pathophysiology of infectious therapy. In this foreword, I will take a helicopter view of diseases, particularly with regard to immunological as- the various aspects of host defense mechanisms with pects of host defense. In the beginning, Robert Good special emphasis on genetic factors, because of their re- called immunodeficiency syndromes “experiments of na- vance for the course and outcome of infections. ture. ” In the 1960s and subsequent decades, the clinical During life, there exist phases of age-related c- and immunological aspects of immune deficiencies were promised immune functions. After birth there is a phys- studied and adequate treatment attempted. A reflection of logical immune deficiency because the production of an- these developments were the three successful meetings on bodies commences slowly upon contact of the neonate these topics in Veldhoven, The Netherlands (1980), Stir- with microorganisms and upon vaccination.
This best-selling resource has a worldwide reputation as the leader in its field. Focusing on human immunology and biology, while also reporting on scientific experimentation and advancement, it provides comprehensive coverage of state-of-the-art basic science as well as authoritative guidance on the practical aspects of day-to-day diagnosis and management. This new edition includes 700 full-color illustrations and a new, more accessible format to make finding information a snap for the busy practitioner. Includes a glossary of allergy and immunology for quick and easy reference. Contains keypoints and clinical pearls highlighted to find important information quickly. links to useful online resources both for you and for your patients. Offers contributions from hundreds of international authorities for world-class expertise in overcoming any clinical challenge. Contains 400 new illustrations, 700 in all, to better illustrate complex immunology. Covers the very latest in the field, including hot topics such as food allergy and immunotherapy. Includes the latest guidelines from The National Asthma Education and Prevention Program (NAEPP). Utilizes a new, more user-friendly full-color format for easier reference.
This widely acclaimed book is a complete, authoritative reference on nutrition and its role in contemporary medicine, dietetics, nursing, public health, and public policy. Distinguished international experts provide in-depth information on historical landmarks in nutrition, specific dietary components, nutrition in integrated biologic systems, nutritional assessment through the life cycle, nutrition in various clinical disorders, and public health and policy issues. Modern Nutrition in Health and Disease, Eleventh Edition, offers coverage of nutrition's role in disease prevention, international nutrition issues, public health concerns, the role of obesity in a variety of chronic illnesses, genetics as it applies to nutrition, and areas of major scientific progress relating nutrition to disease.
This book is a comprehensive, easy-to-read discussion of the organ-specific autoimmune endocrine diseases emphasizing new contributions and trends for research and management. It begins with a brief chapter introducing the general principles of immunology, followed by discussions covering topics such as immunogenetics and animal models and how they can be applied toward interpreting human autoimmune endocrine diseases, autoimmune thyroid diseases, insulin-dependent diabetes mellitus hypophysitis, and Addison's disease. The book also discusses future trends toward gaining an understanding of these disorders and possible therapeutic principles. It is well-illustrated and will prove to be a useful reference source for internists, endocrinologists, and postgraduate students interested in human autoimmune endocrine diseases.
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