During World War I, Germanys plan to control Europe has been thwarted on the battlefield. The Kaisers government now intends to halt the torrent of supplies from America that are sustaining Germanys enemies. A crack team of saboteurs code-named The Black Spiders has arrived in the United States. Their mission is to destroy the factories supplying the Allied armies. The United States is neutral and unprepared for this type of attack. Can the Bureau of Investigations rise to meet the challenge before The Black Spiders spin their web of destruction around America?
This book contends that Indo-European languages came to Greece, central Europe, southern Scandinavia and northern Italy no earlier than ca. 1600 BC, brought by the first military men whom Europeans had seen. That the Greek, Keltic, Italic and Germanic sub-groups of Indo-European originated in the middle of the second millennium BC is a controversial idea. Most Indo-Europeanists date the origin a thousand years earlier, and some archaeologists would place it before 5000 BC, as agriculture spread through Europe. Here Robert Drews argues that the Indo-European languages came into Europe via military conquests, and that militarism – a man’s pride in his weapons and in his status as a warrior - began with the employment of horse-drawn chariots in battle.
Cook-Deegan, a former director of the Biomedical Ethics Advisory Committee of the US Congress and an advisor to the National Center for Human Genome Research, gives a firsthand account of the struggle to launch the Human Genome Project. Using primary documents and interviews, Cook-Deegan explains scientific details, chronicles the origins of the project, covers the conflicts and partnerships between the organizations involved, and examines ethical, legal, and social issues of DNA research. Includes bandw photos. Annotation copyright by Book News, Inc., Portland, OR
This book surveys the range of well-known non-sequential phonological phenomena that are problematic for the traditional one-dimensional idealization of language. It makes a valuable contribution to phonology and phonetics, focusing on the role of these simultaneous features in the relation between phonological representations and the speech signal
Set against a backdrop of terrorism, rogue states, non-conventional warfare, and deteriorating diplomacy, this encyclopedia offers a comprehensive, multidisciplinary, up-to-date reference on the recent history and contemporary practice of arms control and nonproliferation. Arms Control: History, Theory, and Policy features in-depth, expert analysis and information on the full spectrum of issues relating to this critical topic. The first major reference on arms control in over a decade, the two-volume set covers historical context, contemporary challenges, and emerging approaches to diplomacy and human rights. Noted experts provide a full spectrum of perspectives on arms control, offering insightful analysis of arms-control agreements and the people and institutions behind them. Volume 1 provides an accessible historical overview of the subject and a more detailed conceptual analysis of the foundations of arms control. Volume 2 covers the contemporary and practical issues of arms control, focusing on global issues that arms control advocates have been forced to address with varying degrees of success: a burgeoning international trade in conventional weapons; a closely related flood of small arms and light weapons used to fuel intrastate conflicts and even genocide; and the spread of nuclear weapons to potentially unstable regions of the world.
Conducting studies of natural and man-made air contaminants is a specialized research activity that draws upon skills from a variety of disciplines including toxicology, pharmacology, industrial hygiene, and environmental health. Methods in Inhalation Toxicology describes how knowledge from these disciplines is integrated into the design and conduct of inhalation studies. Each of the vital aspects of conducting these studies is discussed in detail, including the use of animal subjects and the related quality control and ethical considerations, air purification methodology, exposure atmosphere generation and characterization, inhalation exposure systems, and real-time and post-exposure biological assessments. These methods will enable you to conduct inhalation studies, easily adding any specific measures of particular interest to your research. The book covers techniques needed to: provide suitable clean air for experiments correctly generate the particles and gases being studied select the proper exposure system monitor the exposure prepare tissues for study ensure that animals do not have confounding lung disease The helpful descriptions and detailed lists of suppliers of preferred equipment and materials will help you to perform valid, reproducible inhalation toxicology studies. Methods in Inhalation Toxicology is a perfect textbook for students in toxicology programs, as well as for scientists who conduct inhalation studies in both academic and industrial environments.
Intonation is a subject of increasing importance in fields from syntax to speech recognition. D. Robert Ladd provides an exceptionally clear presentation of the key ideas of the influential autosegmental-metrical theory of intonational phonology associated with the work of Janet Pierrehumbert. He outlines the evidence for the theory's basic tenets and relates them to the ideas of competing approaches in a way that will allow sceptics to reach an informed opinion and he presents a wealth of new material on the cross-language comparison of intonation couched in autosegmental-metrical terms. He also draws attention to problems in Pierrehumbert's version of the autosegmental-metrical theory, and offers some theoretical proposals of his own. This book will appeal to phonologists and phoneticians as an original contribution to the debates it discusses, and will be welcomed by a wide range of students and researchers as an ideal overview of recent work.
This book is about how plants get diseases, from the origins and evolution of parasites to how the great plant epidemics developed. The basic premise of the book is that the conditions favouring disease are inherent in agriculture and that diseases become destructive because of human activities. It also deals with how people have dealt with plant diseases in history. Included in the book are the natural histories of some of the most damaging plant diseases, worldwide, with discussions of why each became destructive. Diseases are grouped according to the most significant factors in the development of epidemics: in every case this is due to a human factor. Discussion of each model disease proceeds from observable facts to more complex concepts; thus, the reader with little knowledge of plant pathology should find the book easily understandable.
One morning in May 1671, a man disguised as a parson daringly attempted to seize the Crown Jewels from the Tower of London. Astonishingly, he managed to escape with the regalia and crown before being apprehended. And yet he was not executed for treason. Instead, the king granted him a generous income and he became a familiar strutting figure in the royal court's glittering state apartments.This man was Colonel Thomas Blood, a notorious turncoat and fugitive from justice. Nicknamed the 'Father of all Treasons,' he had been involved in an attempted coup d'etat in Ireland as well as countless plots to assassinate Charles II. In an age when gossip and intrigue ruled the coffee houses, the restored Stuart king decided Blood was more useful to him alive than dead. But while serving as his personal spy, Blood was conspiring with his enemies. At the same time he hired himself out as a freelance agent for those seeking to further their political ambition.In The Audacious Crimes of Colonel Blood, bestselling historian Robert Hutchinson paints a vivid portrait of a double agent bent on ambiguous political and personal motivation, and provides an extraordinary account of the perils and conspiracies that abounded in Restoration England.
Many modern geneticists attempt to elucidate the molecular basis of phenotype by utilizing a battery of techniques derived from physical chemistry on subcellular components isolated from various species of organisms. Volume 5 of the Handbook of Genetics provides explanations of the advantages and shortcomings of some of these revolutionary tech niques, and the nonspecialist is alerted to key research papers, reviews, and reference works. Much of the text deals with the structure and func tioning of the molecules bearing genetic information which reside in the nucleus and with the processing of this information by the ribosomes resid ing in the cytoplasm of eukaryotic cells. The mitochondria, which also live in the cytoplasm of the cells of all eukaryotes, now appear to be separate little creatures. These, as Lynn Margulis pointed out in Volume 1, are the colonial posterity of migrant prokaryotes, probably primitive bacteria that swam into the ancestral precursors of all eukaryotic cells and remained as symbionts. They have maintained themselves and their ways ever since, replicating their own DNA and transcribing an RNA quite different from that of their hosts. In a similar manner, the chloroplasts in all plants are self-replicating organelles presumably derived from the blue-green algae, with their own nucleic acids and ribosomes. Four chapters are devoted to the nucleic acids and the ribosomal components of both classes of these semi-independent lodgers. Finally, data from various sources on genetic variants of enzymes are tabulated for ready reference, and an evaluation of this information is attempted.
A Step-by-Step Guide to Present and Future Uses of Microarray TechnologyMicroarray technology continues to evolve, taking on a variety of forms. From the spotting of cDNA and the in situ synthesis of oligonucleotide arrays now come microarrays comprising proteins, carbohydrates, drugs, tissues, and cells. With contributions from microarray experts
The apostle Peter is a pillar of the church whose writing has been overlooked until recently when scholarship remedied this gap, significantly elevating Peter’s letters. However, one critical area has been omitted. Within the Petrine writing is a robust, empowered, and beautiful mystical theology, which makes Peter an unexpected but vital Christian mystic. In exploring his love of artwork, German theologian and priest Romano Guardini developed the Threefold Seeing, which has been brought to light by Yvonne Dohna Schlobitten of the Pontificate Gregorian University. His unique method of viewing the artist, artwork, and observer develops a way of encountering the world and word. Instead of looking at the world or the biblical text through separate vantage points, the Threefold Seeing integrates all disciplines under greater view of God, the artist of all creation. The Letters of an Unexpected Mystic employs Guardini’s Threefold Seeing to encounter the mystic Peter and the Petrine mystical theology. The result is a book that provides its readers with a means to become the Christian Karl Rahner wrote about in 1971: “The devout Christian of the future will either be a ‘mystic,’ one who has ‘experienced’ something, or he will cease to be anything at all.”
This practical laboratory manual provides an essential source of reference, information and guidance for all laboratory and clinical immunologists. It fully describes the methods used in diagnostic immunopathology, and discusses the interpretation and value of the parameters measured. It also answers important practical questions: which parameters are useful in arriving at a diagnosis; which are useful for monitoring the severity of a disease; what level of precision is achievable, and what level is useful; how do we measure accuracy, and how do we achieve inter-laboratory consistency? Each chapter has a brief introduction which provides some general comments on the procedures involved. The methods section contains detailed descriptions with helpful notes on the advantages and disadvantages of different methods and potential pitfalls. Finally, each chapter concludes with a section on clinical applications, which discusses the interpretation, value and limitations of the information obtained, and asks what alternative interpretations should be considered, and what additional information is called for.
Introductory Fourier Transform Spectroscopy discusses the subject of Fourier transform spectroscopy from a level that requires knowledge of only introductory optics and mathematics. The subject is approached through optical principles, not through abstract mathematics. The book approaches the subject matter in two ways. The first is through simple optics and physical intuition, and the second is through Fourier analysis and the concepts of convolution and autocorrelation. This dual treatment bridges the gap between the introductory material in the book and the advanced material in the journals. The book also discusses information theory, Fourier analysis, and mathematical theorems to complete derivations or to give alternate views of an individual subject. The text presents the development of optical theory and equations to the extent required by the advanced student or researcher. The book is intended as a guide for students taking advanced research programs in spectroscopy. Material is included for the physicists, chemists, astronomers, and others who are interested in spectroscopy.
As lawyers move from one firm to another or from private practice into another sphere -- and as firms restructure to meet increasing economic demands -- numerous ethical, practical, and financial questions arise. Hillman on Lawyer Mobility is your definitive guide to this fast developing area of law.Hillman analyzes and clarifies all the urgent legal and ethical ramifications in such areas as: The downsizing of law firmsDisputes over the existence of a partnershipRestrictive covenantsDisincentives to competitionOne-sided fee-sharing agreementsNotice of withdrawalSection 42 elections for withdrawing partnersFiles as property of clientsRetaining liensEnforcement of ethics standards through arbitrationCollateral c
Featuring a fresh layout, revised maps, and more detail than ever before, the seventh edition of Parker's Wine Buyer's Guide offers collectors and amateurs alike the ultimate resource to the world's best wines. Understanding that buyers on every level appreciate a good deal, Parker separates overvalued bottles from undervalued, with wine prices instantly shifting according to his evaluations. Indifferent to the wine's pedigree, Parker's eminent 100-point rating system allows for independent, consumer-oriented, inside information. The latest edition of Parker's Wine Buyer's Guide includes expanded information on Spain, Portugal, Germany, Australia, Argentina, and Chile, as well as new sections on Israel and Central Europe. As in his previous editions, Parker provides the reassurance of a simple number rating, predictions for future buying potential, and practical overviews of regions and grapes. Altogether, an indispensable resource from the man the Los Angeles Times calls “the most powerful critic of any kind.”
Dr. Robert H. Schuller's career has spanned more than five decades, and his ministry of hope has touched the hearts and souls of millions around the world. From one great story to the next, this disarmingly honest autobiography shows us a side of the great preacher that we haven't seen before. My Journey is Dr. Schuller's moving account of his rise from his family's struggling farm in a small Dutch community in Depression-era Iowa to the leadership of a multimillion-member international ministry. With warmth and candor, Schuller tells the stories of the events, the people, and the encounters that shaped his inspiring life and made him the ultimate possibility thinker. Educated in a one-room schoolhouse, Schuller knew from his earliest days that he wanted to be a preacher. He describes times as a boy on the farm when the entire family worked to survive droughts, a tornado, and the Depression. He tells about working his way through Hope College and Western Theological Seminary in Holland, Michigan, where he discovered a message of joy and hope in (of all places) the works of John Calvin. He recounts the excitement of his wedding, the challenges of his first small church in Chicago, and the dramatic story of his coming to Garden Grove, California, in 1955 to found a church in a drive-in theater. Beginning with $500 in assets and his wife, Arvella, as organist, that congregation's phenomenal growth ultimately led to the development of "Hour of Power," the first worldwide television church, and the building of the internationally acclaimed Crystal Cathedral. Dr. Schuller steps down from the pulpit to share the intimate details of the key moments that gave his life and vision their uniquely inspiring character. Using his legendary storytelling ability Dr. Schuller evokes the strict Dutch Calvinist culture of his youth, where dancing was a sin and people really kept the Sabbath. He describes his early sermons and successes evangelizing from the roof of the snack bar at the rented drive-in theater where his ministry took off, and how he was shunned by traditionalists in his denomination for daring to take Christian preaching where it had never gone before. Dr. Schuller shares insights on how his positive-thinking philosophy helped him through the difficult moments of his life, as well as the huge challenges he took on. He recounts meetings with great world teachers such as preachers Norman Vincent Peale and Billy Graham, psychiatrists Karl Menninger and Viktor Frankl, global figures Mikhail Gorbachev, William Clinton, Armand Hammer, and actor John Wayne. Dr. Schuller shares his own spiritual journey as he reflects on his personal life and relationships, charting how he blended the good news of the Gospel with the best of modern psychology. My Journey is a genuinely inspirational and quintessentially American story.
Fundamentals of Analytical Toxicology is an integrated introduction to the analysis of drugs, poisons, and other foreign compounds in biological and related specimens. Assuming only basic knowledge of analytical chemistry, this invaluable guide helps trainee analytical toxicologists understand the principles and practical skills involved in detecting, identifying, and measuring a broad range of compounds in various biological samples. Clear, easy-to-read chapters provide detailed information on topics including sample collection and preparation, spectrophotometric and luminescence techniques, liquid and gas-liquid chromatography, and mass spectrometry including hyphenated techniques. This new edition contains thoroughly revised content that reflects contemporary practices and advances in analytical methods. Expanding the scope of the 1995 World Health Organization (WHO) basic analytical toxicology manual, the text includes coverage of separation science, essential pharmacokinetics, xenobiotic absorption, distribution and metabolism, clinical toxicological and substance misuse testing, therapeutic drug monitoring, trace elements and toxic metals analysis, and importantly the clinical interpretation of analytical results. Written by a prominent team of experienced practitioners, this volume: Focuses on analytical, statistical, and pharmacokinetic principles Describes basic methodology, including colour tests and immunoassay and enzyme-based assays Outlines laboratory operations, such as method validation, quality assessment, staff training, and laboratory accreditation Follows IUPAC nomenclature for chemical names and recommended International Non-proprietary Name (rINN) for drugs and pesticides Includes discussion of 'designer drugs' (novel pharmaceutical substances NPS) Fundamentals of Analytical Toxicology: Clinical and Forensic, 2nd Edition is an indispensable resource for advanced students and trainee analytical toxicologists across disciplines, such as clinical science, analytical chemistry, forensic science, pathology, applied biology, food safety, and pharmaceutical and pesticide development.
In the 1980s, capillary electrophoresis (CE) joined high-performance liquid chromatography (HPLC) as the most powerful separation technique available to analytical chemists and biochemists. Published research using CE grew from 48 papers in the year of commercial introduction (1988) to 1200 in 1997. While only a dozen major pharmaceutical and biotech companies have reduced CE to routine practice, the applications market is showing real or potential growth in key areas, particularly in the DNA marketplace for genomic mapping and forensic identification. For drug development involving small molecules (including chiral separations), one CE instrument can replace 10 liquid chromatographs in terms of speed of analysis. CE also uses aqueous rather than organic solvents and is thus environmentally friendlier than HPLC. The second edition of Practical Capillary Electrophoresis has been extensively reorganized and rewritten to reflect modern usage in the field, with an emphasis on commercially available apparatus and reagents. This authoritative and very comprehensible treatment builds on the author's extensive experience as an instructor of short courses for the American Chemical Society and for industry. - Illustrated with detailed diagrams of electrophoretic phenomena - Offers step-by-step methods development schemes - Presents techniques for developing quantitative, robust, and precise methods - Includes an extensive troubleshooting guide - Updates and greatly expands on the first edition-more than 50% of the text is new - Written by an internationally recognized scientist who is an instructor for American Chemical Society short courses on HPCE
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