Richard W. Wise's Books

The World of Benjamin Cardozo

Personal Values and the Judicial Process

By: Richard Polenberg

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The World of Benjamin Cardozo

Personal Values and the Judicial Process

By: Richard Polenberg

As one of America's most influential judges, first on New York State's Court of Appeals and then on the U.S. Supreme Court, Cardozo oversaw legal transformation daily. How he arrived at his rulings, with their far-reaching consequences, becomes clear in this book, the first to explore the connections between Cardozo's life and his jurisprudence.

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Page Count

330

Publisher

Harvard University Press

Published Date

ISBN 10

0674960521

ISBN 13

9780674960527

The Clerical Guide, Or Ecclesiastical Directory

By: Richard Gilbert

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The Clerical Guide, Or Ecclesiastical Directory

By: Richard Gilbert

The Clerical Guide, Or Ecclesiastical Directory: Containing a Complete Register of the Dignities and Benefices of the Church of England, with the names of their present possessors,patrons &c. and an alphabetical list of the dignitaries and benefits clergy.

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Page Count

341

Publisher

Рипол Классик

ISBN 10

587575804X

ISBN 13

9785875758041

Contrived Competition

Regulation and Deregulation in America

By: Richard H. K. Vietor

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Contrived Competition

Regulation and Deregulation in America

By: Richard H. K. Vietor

And Bank-America, caught short with bad loans and a deep recession in the early eighties, nearly failed before Sam Armacost and then Tom Clausen achieved an amazing turnaround in the mid-1980s.

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Page Count

474

Publisher

Harvard University Press

Published Date

ISBN 10

067416962X

ISBN 13

9780674169623

Live & be Well

A Celebration of Yiddish Culture in America from the First Immigrants to the Second World War

By: Richard F. Shepard,Vicki Gold Levi

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Live & be Well

A Celebration of Yiddish Culture in America from the First Immigrants to the Second World War

By: Richard F. Shepard,Vicki Gold Levi

This book heralds and documents the rich and vibrant traditions of Yiddish-speaking immigrants and their children in the golden land, from the first arrivals until World War II. It presents the famous, infamous and the unknown and is illustrated with photographs, cartoons and theatre posters.

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Page Count

202

Publisher

Rutgers University Press

Published Date

ISBN 10

0813528127

ISBN 13

9780813528120

The Organic Chemistry of Drug Design and Drug Action

By: Richard B. Silverman,Mark W. Holladay

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The Organic Chemistry of Drug Design and Drug Action

By: Richard B. Silverman,Mark W. Holladay

The Organic Chemistry of Drug Design and Drug Action, Third Edition, represents a unique approach to medicinal chemistry based on physical organic chemical principles and reaction mechanisms that rationalize drug action, which allows reader to extrapolate those core principles and mechanisms to many related classes of drug molecules. This new edition includes updates to all chapters, including new examples and references. It reflects significant changes in the process of drug design over the last decade and preserves the successful approach of the previous editions while including significant changes in format and coverage. This text is designed for undergraduate and graduate students in chemistry studying medicinal chemistry or pharmaceutical chemistry; research chemists and biochemists working in pharmaceutical and biotechnology industries. - Updates to all chapters, including new examples and references - Chapter 1 (Introduction): Completely rewritten and expanded as an overview of topics discussed in detail throughout the book - Chapter 2 (Lead Discovery and Lead Modification): Sections on sources of compounds for screening including library collections, virtual screening, and computational methods, as well as hit-to-lead and scaffold hopping; expanded sections on sources of lead compounds, fragment-based lead discovery, and molecular graphics; and deemphasized solid-phase synthesis and combinatorial chemistry - Chapter 3 (Receptors): Drug-receptor interactions, cation-p and halogen bonding; atropisomers; case history of the insomnia drug suvorexant - Chapter 4 (Enzymes): Expanded sections on enzyme catalysis in drug discovery and enzyme synthesis - Chapter 5 (Enzyme Inhibition and Inactivation): New case histories: - for competitive inhibition, the epidermal growth factor receptor tyrosine kinase inhibitor, erlotinib and Abelson kinase inhibitor, imatinib - for transition state analogue inhibition, the purine nucleoside phosphorylase inhibitors, forodesine and DADMe-ImmH, as well as the mechanism of the multisubstrate analog inhibitor isoniazid - for slow, tight-binding inhibition, the dipeptidyl peptidase-4 inhibitor, saxagliptin - Chapter 7 (Drug Resistance and Drug Synergism): This new chapter includes topics taken from two chapters in the previous edition, with many new examples - Chapter 8 (Drug Metabolism): Discussions of toxicophores and reactive metabolites - Chapter 9 (Prodrugs and Drug Delivery Systems): Discussion of antibody–drug conjugates

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Page Count

537

Publisher

Academic Press

Published Date

ISBN 10

0123820316

ISBN 13

9780123820310

Stem Cell Therapy for Autoimmune Disease

By: Richard K. Burt

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Stem Cell Therapy for Autoimmune Disease

By: Richard K. Burt

Stem cell transplantation may be complicated by treatment-related mortality and like the immune system that it regenerates has equal potential to either create and preserve or destroy. The dual nature that defines stem cells is differentiation that ultimately leads to death and self-renewal, which leads to immortality. What types of stem cells are there? How are they collected? What are their attributes and characteristics? This textbook devotes many chapters to familiarize the reader with the basic science, clinical aspects, and new questions being raised in the field of stem cell biology. Blood stem cells for tolerance and tissue regeneration are a rapidly developing research and clinical field that is being applied to autoimmune diseases. In clinical trials, autologous hematopoietic (blood) stem cells are being used to reduce the cytopenic interval following intense immune suppressive transplant regimens. While as yet not delineated, some possible mechanisms and pathways leading to tolerance after hematopoietic stem cell transplantation are suggested in these chapters. Tissue regeneration from blood stem cells is also suggested by animal experiments on stem cell plasticity or metamoirosis (i.e., change in fate) as described within this textbook. Ongoing early clinical trials on tissue regeneration from blood stem cells are described in the chapter on stem cell therapy for cardiac and peripheral vascular disease. Whether autologous hematopoietic stem cells, through the process of mobilization and reinfusion, may be manipulated to contribute to tissue repair in autoimmune diseases is a future area for translational research.

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Page Count

1406

Publisher

CRC Press

Published Date

ISBN 10

1000724670

ISBN 13

9781000724677

Wirt County

By: Richard T. Lowe

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Wirt County

By: Richard T. Lowe

Wirt County was established by an act of the Virginia General Assembly on January 19, 1848, and was named in honor of William Wirt, a famed prosecutor representing the United States in the trial of Vice Pres. Aaron Burr, who was accused of treason. In 1859, the county's population escalated from just a few dozen to several thousand as news of the nation's first big oil boom in Burning Springs was publicized in headlines across the globe. The oil industry had a profound impact on the future of Wirt County and even played a pivotal role in West Virginia being admitted into the Union. While the heyday of the oil industry has faded, the charm of Wirt County has not--it is here where many families embrace the quiet, peaceful lifestyle that a small community offers.

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Page Count

132

Publisher

Arcadia Publishing

Published Date

ISBN 10

0738566799

ISBN 13

9780738566795

GroupWise 5.2

Administrator's Guide

By: Richard Beels,Danita Zanre,Scott Kunau

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GroupWise 5.2

Administrator's Guide

By: Richard Beels,Danita Zanre,Scott Kunau

to expand its installed base of over 5 million GroupWise users worldwide. This book offers clear explanations of administrative tasks and will help network administrators optimize the efficiency of an Intranet or groupware environment using GroupWise. The CD contains numerous administrative tools and utilities.

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Page Count

868

Publisher

Sybex

Published Date

ISBN 10

078211993X

ISBN 13

9780782119930

A Global Warming Forum

Scientific, Economic, and Legal Overview

By: Richard A. Geyer

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A Global Warming Forum

Scientific, Economic, and Legal Overview

By: Richard A. Geyer

A Global Warming Forum: Scientific, Economic, and Legal Overview provides an integrated, thematic approach to major critical aspects of the problem presented by global warming. Scientific issues; economics; natural resource management concerns; and legal, educational, and policy considerations are discussed within the context of arriving at solutions to global warming problems. Data and information is derived from diverse geographic locations, especially in the case history chapters requiring the use of integrated interdisciplinary methods. Graphs and tables are used extensively throughout the text to illustrate key concepts. A Global Warming Forum: Scientific, Economic, and Legal Overview is an excellent survey for researchers in all areas of geoscience and climate assessment, including geochemistry, oceanography, climatology, and resource management.

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Page Count

676

Publisher

CRC Press

Published Date

ISBN 10

0849344190

ISBN 13

9780849344190

Wisdom

Life's Great Treasure

By: Richard E. Simmons III

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Wisdom

Life's Great Treasure

By: Richard E. Simmons III

This book is a collection of short essays on wisdom in 12 areas of life - The Nature of Wisdom, Personal Growth and Development, Wisdom and True Freedom, Wisdom in the Search for Meaning, Business & Career Wisdom, Financial Wisdom, Relational Wisdom, Human Sexuality, Care of the Soul, Healthy Life, The Storms of Life, Facing Our Mortality.

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Page Count

252

Publisher

Union Hill PUblishing

Published Date

ISBN 10

1939358132

ISBN 13

9781939358134

Book's by Richard W. Wise

The World of Benjamin Cardozo

The World of Benjamin Cardozo

The Clerical Guide, Or Ecclesiastical Directory

The Clerical Guide, Or Ecclesiastical Directory

Contrived Competition

Contrived Competition

Live & be Well

Live & be Well

The Organic Chemistry of Drug Design and Drug Action

The Organic Chemistry of Drug Design and Drug Action

Stem Cell Therapy for Autoimmune Disease

Stem Cell Therapy for Autoimmune Disease

Wirt County

Wirt County

GroupWise 5.2

GroupWise 5.2

A Global Warming Forum

A Global Warming Forum

Wisdom

Wisdom

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